Henry Ou

Summary

Affiliation: University of Washington
Country: USA

Publications

  1. pmc "In-bone" utricle cultures--a simplified, atraumatic technique for in situ cultures of the adult mouse (Mus musculus) utricle
    Henry C Ou
    Virginia Merrill Bloedel Hearing Research Center, Department of Otolaryngology Head and Neck Surgery, University of Washington, Seattle, WA 98195, USA
    Otol Neurotol 34:353-9. 2013
  2. pmc Screening for chemicals that affect hair cell death and survival in the zebrafish lateral line
    Henry Ou
    Virginia Merrill Bloedel Hearing Research Center, University of Washington, Box 357923, Seattle, WA 98195 7923, USA
    Hear Res 288:58-66. 2012
  3. pmc Quinoline ring derivatives protect against aminoglycoside-induced hair cell death in the zebrafish lateral line
    Henry C Ou
    Virginia Merrill Bloedel Hearing Research Center, University of Washington, Box 357923, Seattle, WA 98195 7293, USA
    J Assoc Res Otolaryngol 13:759-70. 2012
  4. doi request reprint Assessing the immunization status of pediatric cochlear implant recipients using a state-maintained immunization registry
    Henry Ou
    Childhood Communication Center, Seattle Children s Hospital, Seattle, WA, USA
    Otolaryngol Head Neck Surg 143:487-91. 2010
  5. pmc Cisplatin-induced hair cell loss in zebrafish (Danio rerio) lateral line
    Henry C Ou
    Virginia Merrill Bloedel Hearing Research Center, University of Washington, Box 357923, Seattle, WA 98195, USA
    Hear Res 233:46-53. 2007
  6. pmc Drug screening for hearing loss: using the zebrafish lateral line to screen for drugs that prevent and cause hearing loss
    Henry C Ou
    Virginia Merrill Bloedel Hearing Research Center, University of Washington, Box 357923, Seattle, WA 98195, USA
    Drug Discov Today 15:265-71. 2010
  7. pmc Identification of FDA-approved drugs and bioactives that protect hair cells in the zebrafish (Danio rerio) lateral line and mouse (Mus musculus) utricle
    Henry C Ou
    Virginia Merrill Bloedel Hearing Research Center, University of Washington, Box 357923, Seattle, WA 98195, USA
    J Assoc Res Otolaryngol 10:191-203. 2009
  8. pmc Chemical screening for hair cell loss and protection in the zebrafish lateral line
    Allison B Coffin
    Virginia Merrill Bloedel Hearing Research Center, University of Washington, Seattle, Washington 98195 7923, USA
    Zebrafish 7:3-11. 2010
  9. pmc Using the zebrafish lateral line to screen for ototoxicity
    Lynn L Chiu
    Department of Otolaryngology Head and Neck Surgery, University of Washington, Box 356515, Seattle, WA 98195, USA
    J Assoc Res Otolaryngol 9:178-90. 2008
  10. doi request reprint Polymerase chain reaction for pathogen identification in persistent pediatric cervical lymphadenitis
    Peter Choi
    Department of Otolaryngology Head and Neck Surgery, University of Washington, Seattle, WA, USA
    Arch Otolaryngol Head Neck Surg 135:243-8. 2009

Collaborators

Detail Information

Publications10

  1. pmc "In-bone" utricle cultures--a simplified, atraumatic technique for in situ cultures of the adult mouse (Mus musculus) utricle
    Henry C Ou
    Virginia Merrill Bloedel Hearing Research Center, Department of Otolaryngology Head and Neck Surgery, University of Washington, Seattle, WA 98195, USA
    Otol Neurotol 34:353-9. 2013
    ..The "in-bone" method of culturing utricles described here is a reliable and atraumatic technique for culturing mature mouse hair cells and studying hair cell death and protection...
  2. pmc Screening for chemicals that affect hair cell death and survival in the zebrafish lateral line
    Henry Ou
    Virginia Merrill Bloedel Hearing Research Center, University of Washington, Box 357923, Seattle, WA 98195 7923, USA
    Hear Res 288:58-66. 2012
    ..In this review, we focus on the results of our previous screens and the evolving methodology of our screens for chemicals that protect hair cells, and chemicals that damage hair cells using the zebrafish lateral line...
  3. pmc Quinoline ring derivatives protect against aminoglycoside-induced hair cell death in the zebrafish lateral line
    Henry C Ou
    Virginia Merrill Bloedel Hearing Research Center, University of Washington, Box 357923, Seattle, WA 98195 7293, USA
    J Assoc Res Otolaryngol 13:759-70. 2012
    ..However, all eight protective drugs were found to reduce the uptake of aminoglycosides into hair cells. Subsequent experiments suggest that reduction of uptake is the primary mechanism of protection among the quinoline drugs...
  4. doi request reprint Assessing the immunization status of pediatric cochlear implant recipients using a state-maintained immunization registry
    Henry Ou
    Childhood Communication Center, Seattle Children s Hospital, Seattle, WA, USA
    Otolaryngol Head Neck Surg 143:487-91. 2010
    ....
  5. pmc Cisplatin-induced hair cell loss in zebrafish (Danio rerio) lateral line
    Henry C Ou
    Virginia Merrill Bloedel Hearing Research Center, University of Washington, Box 357923, Seattle, WA 98195, USA
    Hear Res 233:46-53. 2007
    ..These data demonstrate the feasibility and repeatability of cisplatin damage protocols in the zebrafish lateral line and set the stage for future evaluations of modulation of cisplatin-induced hair cell death...
  6. pmc Drug screening for hearing loss: using the zebrafish lateral line to screen for drugs that prevent and cause hearing loss
    Henry C Ou
    Virginia Merrill Bloedel Hearing Research Center, University of Washington, Box 357923, Seattle, WA 98195, USA
    Drug Discov Today 15:265-71. 2010
    ..The identification of multiple drugs and drug-like compounds that inhibit multiple hair cell death pathways might enable the development of protective cocktails to achieve complete hair cell protection...
  7. pmc Identification of FDA-approved drugs and bioactives that protect hair cells in the zebrafish (Danio rerio) lateral line and mouse (Mus musculus) utricle
    Henry C Ou
    Virginia Merrill Bloedel Hearing Research Center, University of Washington, Box 357923, Seattle, WA 98195, USA
    J Assoc Res Otolaryngol 10:191-203. 2009
    ....
  8. pmc Chemical screening for hair cell loss and protection in the zebrafish lateral line
    Allison B Coffin
    Virginia Merrill Bloedel Hearing Research Center, University of Washington, Seattle, Washington 98195 7923, USA
    Zebrafish 7:3-11. 2010
    ..We discuss chemical screens to identify compounds that induce hair cell loss and others that protect hair cells from known toxins and the potential application of these screens to human medicine...
  9. pmc Using the zebrafish lateral line to screen for ototoxicity
    Lynn L Chiu
    Department of Otolaryngology Head and Neck Surgery, University of Washington, Box 356515, Seattle, WA 98195, USA
    J Assoc Res Otolaryngol 9:178-90. 2008
    ..This study represents an important step in validating the use of the zebrafish lateral line as a screening tool for the identification of potentially ototoxic drugs...
  10. doi request reprint Polymerase chain reaction for pathogen identification in persistent pediatric cervical lymphadenitis
    Peter Choi
    Department of Otolaryngology Head and Neck Surgery, University of Washington, Seattle, WA, USA
    Arch Otolaryngol Head Neck Surg 135:243-8. 2009
    ..To study routine culture-negative persistent cervical lymphadenitis in children treated surgically during a 10-year period (December 26, 1997, to October 1, 2007) at a single institution...