Daniel J O'Sullivan

Summary

Affiliation: University of Minnesota
Country: USA

Publications

  1. ncbi Expression of the cationic antimicrobial peptide lactoferricin fused with the anionic peptide in Escherichia coli
    Ha-Kun Kim
    Department of Genetic Engineering, Paichai University, 439-6, Doma-dong, Seo-Ku, Daejon, 302-735, South Korea
    Appl Microbiol Biotechnol 72:330-8. 2006
  2. ncbi Comparative genomic analysis of the gut bacterium Bifidobacterium longum reveals loci susceptible to deletion during pure culture growth
    Ju Hoon Lee
    Department of Food Science and Nutrition, Center for Microbial and Plant Genomics, University of Minnesota, 1500 Gortner Ave, St Paul, MN 55108, USA
    BMC Genomics 9:247. 2008
  3. ncbi Effect of a synbiotic yogurt on levels of fecal bifidobacteria, clostridia, and enterobacteria
    Amrita Palaria
    Department of Food Science and Nutrition, Center for Microbial and Plant Genomics, University of Minnesota, St Paul, Minnesota, USA
    Appl Environ Microbiol 78:933-40. 2012
  4. ncbi Genomics can advance the potential for probiotic cultures to improve liver and overall health
    Daniel J O'Sullivan
    Department of Food Science and Nutrition, Center for Microbial and Plant Genomics, Cargill Building for Microbial and Plant Genomics, St Paul, Minnesota 55108, USA
    Curr Pharm Des 14:1376-81. 2008
  5. ncbi Screening of intestinal microflora for effective probiotic bacteria
    D J O'Sullivan
    Department of Food Science and Nutrition, University of Minnesota, 1334 Eckles Avenue, St Paul, Minnesota 55108, USA
    J Agric Food Chem 49:1751-60. 2001
  6. ncbi Sequence analysis of two cryptic plasmids from Bifidobacterium longum DJO10A and construction of a shuttle cloning vector
    Ju Hoon Lee
    Cargill Building for Microbial and Plant Genomics, 1500 Gortner Ave, St Paul, MN 55108
    Appl Environ Microbiol 72:527-35. 2006
  7. ncbi Comparative sequence analysis of plasmids from Lactobacillus delbrueckii and construction of a shuttle cloning vector
    Ju Hoon Lee
    Department of Food Science and Nutrition and Center for Microbial and Plant Genomics, University of Minnesota, Cargill Building for Microbial and Plant Genomics, St Paul, MN 55108, USA
    Appl Environ Microbiol 73:4417-24. 2007
  8. ncbi Genomic insights into bifidobacteria
    Ju Hoon Lee
    Department of Food Science and Nutrition, Microbial and Plant Genomics Institute, University of Minnesota, 1500 Gortner Ave, St Paul, MN 55108, USA
    Microbiol Mol Biol Rev 74:378-416. 2010
  9. ncbi Transcription analysis of a lantibiotic gene cluster from Bifidobacterium longum DJO10A
    Ju Hoon Lee
    Department of Food Science and Nutrition, Microbial and Plant Genomics Institute, University of Minnesota, 1500 Gortner Ave, St Paul, MN 55108, USA
    Appl Environ Microbiol 77:5879-87. 2011
  10. ncbi Contribution of the Actinobacteria to the growing diversity of lantibiotics
    Xiulan Li
    Department of Food Science and Nutrition, Microbial and Plant Genomics Institute, University of Minnesota, St Paul, MN 55108, USA
    Biotechnol Lett 34:2133-45. 2012

Collaborators

Detail Information

Publications11

  1. ncbi Expression of the cationic antimicrobial peptide lactoferricin fused with the anionic peptide in Escherichia coli
    Ha-Kun Kim
    Department of Genetic Engineering, Paichai University, 439-6, Doma-dong, Seo-Ku, Daejon, 302-735, South Korea
    Appl Microbiol Biotechnol 72:330-8. 2006
    ..The recombinant lactoferricin showed antimicrobial activity and disrupted bacterial membrane permeability, as the native lactoferricin peptide does...
  2. ncbi Comparative genomic analysis of the gut bacterium Bifidobacterium longum reveals loci susceptible to deletion during pure culture growth
    Ju Hoon Lee
    Department of Food Science and Nutrition, Center for Microbial and Plant Genomics, University of Minnesota, 1500 Gortner Ave, St Paul, MN 55108, USA
    BMC Genomics 9:247. 2008
    ..However, clinical feeding studies with exogenous bifidobacteria show they don't remain in the intestine, suggesting they may lose competitive fitness when grown outside the gut...
  3. ncbi Effect of a synbiotic yogurt on levels of fecal bifidobacteria, clostridia, and enterobacteria
    Amrita Palaria
    Department of Food Science and Nutrition, Center for Microbial and Plant Genomics, University of Minnesota, St Paul, Minnesota, USA
    Appl Environ Microbiol 78:933-40. 2012
    ..While this synbiotic yogurt can increase bifidobacterial numbers and decrease clostridial numbers (but not enterobacterial numbers) in some individuals, it cannot modulate these microbial groups in the majority of individuals...
  4. ncbi Genomics can advance the potential for probiotic cultures to improve liver and overall health
    Daniel J O'Sullivan
    Department of Food Science and Nutrition, Center for Microbial and Plant Genomics, Cargill Building for Microbial and Plant Genomics, St Paul, Minnesota 55108, USA
    Curr Pharm Des 14:1376-81. 2008
    ..The genomics era is now providing the tools to more effectively understand probiotic interactions in the intestine. This will lead to a new generation of exciting probiotics in the future...
  5. ncbi Screening of intestinal microflora for effective probiotic bacteria
    D J O'Sullivan
    Department of Food Science and Nutrition, University of Minnesota, 1334 Eckles Avenue, St Paul, Minnesota 55108, USA
    J Agric Food Chem 49:1751-60. 2001
    ..This review will detail these scientific approaches and how their impact will improve criteria for selection of probiotic bacteria...
  6. ncbi Sequence analysis of two cryptic plasmids from Bifidobacterium longum DJO10A and construction of a shuttle cloning vector
    Ju Hoon Lee
    Cargill Building for Microbial and Plant Genomics, 1500 Gortner Ave, St Paul, MN 55108
    Appl Environ Microbiol 72:527-35. 2006
    ..This is the first cloning vector for bifidobacteria that does not utilize RCR and should be useful for the stable introduction of heterologous genes into these dominant inhabitants of the large intestine...
  7. ncbi Comparative sequence analysis of plasmids from Lactobacillus delbrueckii and construction of a shuttle cloning vector
    Ju Hoon Lee
    Department of Food Science and Nutrition and Center for Microbial and Plant Genomics, University of Minnesota, Cargill Building for Microbial and Plant Genomics, St Paul, MN 55108, USA
    Appl Environ Microbiol 73:4417-24. 2007
    ..coli, L. delbrueckii subsp. bulgaricus, S. thermophilus, and Lactococcus lactis. This shuttle cloning vector provides a new tool for molecular analysis of Lactobacillus delbrueckii and other lactic acid bacteria...
  8. ncbi Genomic insights into bifidobacteria
    Ju Hoon Lee
    Department of Food Science and Nutrition, Microbial and Plant Genomics Institute, University of Minnesota, 1500 Gortner Ave, St Paul, MN 55108, USA
    Microbiol Mol Biol Rev 74:378-416. 2010
    ..animalis subsp. lactis strains, which exhibit the least potential for a gut habitat and are believed to have evolved from the B. animalis species during adaptation to dairy fermentation environments...
  9. ncbi Transcription analysis of a lantibiotic gene cluster from Bifidobacterium longum DJO10A
    Ju Hoon Lee
    Department of Food Science and Nutrition, Microbial and Plant Genomics Institute, University of Minnesota, 1500 Gortner Ave, St Paul, MN 55108, USA
    Appl Environ Microbiol 77:5879-87. 2011
    ..Understanding the transcription regulation of this lanA gene is the first step toward enabling production of this novel and potentially interesting lantibiotic in broth cultures...
  10. ncbi Contribution of the Actinobacteria to the growing diversity of lantibiotics
    Xiulan Li
    Department of Food Science and Nutrition, Microbial and Plant Genomics Institute, University of Minnesota, St Paul, MN 55108, USA
    Biotechnol Lett 34:2133-45. 2012
    ..In addition, a phylogenetic classification system based on the full prepropeptide sequences showed remarkable consistency with current classification systems and may provide a more rapid and convenient means for classifying lantibiotics...
  11. ncbi Prophage-like elements in bifidobacteria: insights from genomics, transcription, integration, distribution, and phylogenetic analysis
    Marco Ventura
    Alimentary Pharmabiotic Centre and Department of Microbiology, Biosciences Institute, National University of Ireland, Western Road, Cork, Ireland
    Appl Environ Microbiol 71:8692-705. 2005
    ..Interestingly, a gene predicted to encode an extracellular beta-glucosidase carried within the Bbr-1 prophage-like element was shown to be transcribed...