Daniel J O'Sullivan

Summary

Affiliation: University of Minnesota
Country: USA

Publications

  1. ncbi request reprint Expression of the cationic antimicrobial peptide lactoferricin fused with the anionic peptide in Escherichia coli
    Ha Kun Kim
    Department of Genetic Engineering, Paichai University, 439 6, Doma dong, Seo Ku, Daejon, 302 735, South Korea
    Appl Microbiol Biotechnol 72:330-8. 2006
  2. pmc Comparative genomic analysis of the gut bacterium Bifidobacterium longum reveals loci susceptible to deletion during pure culture growth
    Ju Hoon Lee
    Department of Food Science and Nutrition, Center for Microbial and Plant Genomics, University of Minnesota, 1500 Gortner Ave, St Paul, MN 55108, USA
    BMC Genomics 9:247. 2008
  3. pmc Effect of a synbiotic yogurt on levels of fecal bifidobacteria, clostridia, and enterobacteria
    Amrita Palaria
    Department of Food Science and Nutrition, Center for Microbial and Plant Genomics, University of Minnesota, St Paul, Minnesota, USA
    Appl Environ Microbiol 78:933-40. 2012
  4. ncbi request reprint Screening of intestinal microflora for effective probiotic bacteria
    D J O'Sullivan
    Department of Food Science and Nutrition, University of Minnesota, 1334 Eckles Avenue, St Paul, Minnesota 55108, USA
    J Agric Food Chem 49:1751-60. 2001
  5. ncbi request reprint Genomics can advance the potential for probiotic cultures to improve liver and overall health
    Daniel J O'Sullivan
    Department of Food Science and Nutrition, Center for Microbial and Plant Genomics, Cargill Building for Microbial and Plant Genomics, St Paul, Minnesota 55108, USA
    Curr Pharm Des 14:1376-81. 2008
  6. pmc Sequence analysis of two cryptic plasmids from Bifidobacterium longum DJO10A and construction of a shuttle cloning vector
    Ju Hoon Lee
    Cargill Building for Microbial and Plant Genomics, 1500 Gortner Ave, St Paul, MN 55108
    Appl Environ Microbiol 72:527-35. 2006
  7. pmc Comparative sequence analysis of plasmids from Lactobacillus delbrueckii and construction of a shuttle cloning vector
    Ju Hoon Lee
    Department of Food Science and Nutrition and Center for Microbial and Plant Genomics, University of Minnesota, Cargill Building for Microbial and Plant Genomics, St Paul, MN 55108, USA
    Appl Environ Microbiol 73:4417-24. 2007
  8. ncbi request reprint Characterization of the promoter regions involved in galactose- and nisin-mediated induction of the nisA gene in Lactococcus lactis ATCC 11454
    Sailaja Chandrapati
    Department of Food Science and Nutrition, University of Minnesota, St Paul, MN 55108, USA
    Mol Microbiol 46:467-77. 2002
  9. doi request reprint Developing an efficient and reproducible conjugation-based gene transfer system for bifidobacteria
    Wilfredo Dominguez
    Department of Food Science and Nutrition, Cargill Building for Microbial and Plant Genomics, Microbial and Plant Genomics Institute, University of Minnesota, 1500 Gortner Avenue, St Paul, MN 55108 1038, USA
    Microbiology 159:328-38. 2013
  10. pmc Genomic insights into bifidobacteria
    Ju Hoon Lee
    Department of Food Science and Nutrition, Microbial and Plant Genomics Institute, University of Minnesota, 1500 Gortner Ave, St Paul, MN 55108, USA
    Microbiol Mol Biol Rev 74:378-416. 2010

Collaborators

  • Ju Hoon Lee
  • Xiulan Li
  • Haiping Li
  • Marco Ventura
  • Wilfredo Dominguez
  • Amrita Palaria
  • Julie M Yang
  • Ha Kun Kim
  • Trevor G Phister
  • Sailaja Chandrapati
  • Ivy Johnson-Kanda
  • Joon Sik Kim
  • Nadya Matvienko
  • Soon Kwang Hong
  • Cheol Ho Yun
  • Patricio J Deurraza
  • Dae Sik Chun
  • Dae Kyung Kang
  • Larry L McKay

Detail Information

Publications16

  1. ncbi request reprint Expression of the cationic antimicrobial peptide lactoferricin fused with the anionic peptide in Escherichia coli
    Ha Kun Kim
    Department of Genetic Engineering, Paichai University, 439 6, Doma dong, Seo Ku, Daejon, 302 735, South Korea
    Appl Microbiol Biotechnol 72:330-8. 2006
    ..The recombinant lactoferricin showed antimicrobial activity and disrupted bacterial membrane permeability, as the native lactoferricin peptide does...
  2. pmc Comparative genomic analysis of the gut bacterium Bifidobacterium longum reveals loci susceptible to deletion during pure culture growth
    Ju Hoon Lee
    Department of Food Science and Nutrition, Center for Microbial and Plant Genomics, University of Minnesota, 1500 Gortner Ave, St Paul, MN 55108, USA
    BMC Genomics 9:247. 2008
    ..However, clinical feeding studies with exogenous bifidobacteria show they don't remain in the intestine, suggesting they may lose competitive fitness when grown outside the gut...
  3. pmc Effect of a synbiotic yogurt on levels of fecal bifidobacteria, clostridia, and enterobacteria
    Amrita Palaria
    Department of Food Science and Nutrition, Center for Microbial and Plant Genomics, University of Minnesota, St Paul, Minnesota, USA
    Appl Environ Microbiol 78:933-40. 2012
    ..While this synbiotic yogurt can increase bifidobacterial numbers and decrease clostridial numbers (but not enterobacterial numbers) in some individuals, it cannot modulate these microbial groups in the majority of individuals...
  4. ncbi request reprint Screening of intestinal microflora for effective probiotic bacteria
    D J O'Sullivan
    Department of Food Science and Nutrition, University of Minnesota, 1334 Eckles Avenue, St Paul, Minnesota 55108, USA
    J Agric Food Chem 49:1751-60. 2001
    ..This review will detail these scientific approaches and how their impact will improve criteria for selection of probiotic bacteria...
  5. ncbi request reprint Genomics can advance the potential for probiotic cultures to improve liver and overall health
    Daniel J O'Sullivan
    Department of Food Science and Nutrition, Center for Microbial and Plant Genomics, Cargill Building for Microbial and Plant Genomics, St Paul, Minnesota 55108, USA
    Curr Pharm Des 14:1376-81. 2008
    ..The genomics era is now providing the tools to more effectively understand probiotic interactions in the intestine. This will lead to a new generation of exciting probiotics in the future...
  6. pmc Sequence analysis of two cryptic plasmids from Bifidobacterium longum DJO10A and construction of a shuttle cloning vector
    Ju Hoon Lee
    Cargill Building for Microbial and Plant Genomics, 1500 Gortner Ave, St Paul, MN 55108
    Appl Environ Microbiol 72:527-35. 2006
    ..This is the first cloning vector for bifidobacteria that does not utilize RCR and should be useful for the stable introduction of heterologous genes into these dominant inhabitants of the large intestine...
  7. pmc Comparative sequence analysis of plasmids from Lactobacillus delbrueckii and construction of a shuttle cloning vector
    Ju Hoon Lee
    Department of Food Science and Nutrition and Center for Microbial and Plant Genomics, University of Minnesota, Cargill Building for Microbial and Plant Genomics, St Paul, MN 55108, USA
    Appl Environ Microbiol 73:4417-24. 2007
    ..coli, L. delbrueckii subsp. bulgaricus, S. thermophilus, and Lactococcus lactis. This shuttle cloning vector provides a new tool for molecular analysis of Lactobacillus delbrueckii and other lactic acid bacteria...
  8. ncbi request reprint Characterization of the promoter regions involved in galactose- and nisin-mediated induction of the nisA gene in Lactococcus lactis ATCC 11454
    Sailaja Chandrapati
    Department of Food Science and Nutrition, University of Minnesota, St Paul, MN 55108, USA
    Mol Microbiol 46:467-77. 2002
    ..As this effectively made the Leloir pathway redundant, it points to some component of this pathway as the specific inducer of the nisA promoter...
  9. doi request reprint Developing an efficient and reproducible conjugation-based gene transfer system for bifidobacteria
    Wilfredo Dominguez
    Department of Food Science and Nutrition, Cargill Building for Microbial and Plant Genomics, Microbial and Plant Genomics Institute, University of Minnesota, 1500 Gortner Avenue, St Paul, MN 55108 1038, USA
    Microbiology 159:328-38. 2013
    ....
  10. pmc Genomic insights into bifidobacteria
    Ju Hoon Lee
    Department of Food Science and Nutrition, Microbial and Plant Genomics Institute, University of Minnesota, 1500 Gortner Ave, St Paul, MN 55108, USA
    Microbiol Mol Biol Rev 74:378-416. 2010
    ..animalis subsp. lactis strains, which exhibit the least potential for a gut habitat and are believed to have evolved from the B. animalis species during adaptation to dairy fermentation environments...
  11. pmc Transcription analysis of a lantibiotic gene cluster from Bifidobacterium longum DJO10A
    Ju Hoon Lee
    Department of Food Science and Nutrition, Microbial and Plant Genomics Institute, University of Minnesota, 1500 Gortner Ave, St Paul, MN 55108, USA
    Appl Environ Microbiol 77:5879-87. 2011
    ..Understanding the transcription regulation of this lanA gene is the first step toward enabling production of this novel and potentially interesting lantibiotic in broth cultures...
  12. pmc Heterologous expression of the Lactococcus lactis bacteriocin, nisin, in a dairy Enterococcus strain
    Haiping Li
    Department of Food Science and Nutrition, University of Minnesota, 1334 Eckles Avenue, St Paul, MN 55108, USA
    Appl Environ Microbiol 68:3392-400. 2002
    ..strain N12beta depended on autoinduction via signal transduction. However, the amount of external inducing signal required was significantly greater than the amount needed for autoinduction in L. lactis...
  13. doi request reprint Contribution of the Actinobacteria to the growing diversity of lantibiotics
    Xiulan Li
    Department of Food Science and Nutrition, Microbial and Plant Genomics Institute, University of Minnesota, St Paul, MN 55108, USA
    Biotechnol Lett 34:2133-45. 2012
    ..In addition, a phylogenetic classification system based on the full prepropeptide sequences showed remarkable consistency with current classification systems and may provide a more rapid and convenient means for classifying lantibiotics...
  14. pmc Identification of bacilysin, chlorotetaine, and iturin a produced by Bacillus sp. strain CS93 isolated from pozol, a Mexican fermented maize dough
    Trevor G Phister
    Department of Food Science and Nutrition, University of Minnesota, St Paul, Minnesota 55108, USA
    Appl Environ Microbiol 70:631-4. 2004
    ..The three compounds were iturin, bacilysin, and chlorotetaine. Production of these compounds by CS93 could account for the medicinal properties attributed to pozol...
  15. pmc Involvement of the LlaKR2I methylase in expression of the AbiR bacteriophage defense system in Lactococcus lactis subsp. lactis biovar diacetylactis KR2
    Julie M Yang
    Department of Food Science and Nutrition, Cargill Building for Microbial and Plant Genomics, University of Minnesota, 1500 Gortner Avenue, Saint Paul, MN 55108, USA
    J Bacteriol 188:1920-8. 2006
    ..This new role for the LlaKR2I methylase offers a unique snapshot into the evolution of the cell cycle-regulated methylases from an existing R/M system...
  16. pmc Prophage-like elements in bifidobacteria: insights from genomics, transcription, integration, distribution, and phylogenetic analysis
    Marco Ventura
    Alimentary Pharmabiotic Centre and Department of Microbiology, Biosciences Institute, National University of Ireland, Western Road, Cork, Ireland
    Appl Environ Microbiol 71:8692-705. 2005
    ..Interestingly, a gene predicted to encode an extracellular beta-glucosidase carried within the Bbr-1 prophage-like element was shown to be transcribed...