Research Topics
| Padraig E O'SuilleabhainSummaryAffiliation: University of Texas Southwestern Medical Center Country: USA Publications
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Detail Information
Publications
Proprioception in Parkinson's disease is acutely depressed by dopaminergic medicationsP O'Suilleabhain
Department of Neurology, University of Texas, Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390 9036, USA
J Neurol Neurosurg Psychiatry 71:607-10. 2001..This study tested for effects on proprioception of dopaminergic drugs, and for associations between such effects and drug induced dyskinesias...
Elevated plasma homocysteine level in patients with Parkinson disease: motor, affective, and cognitive associationsPadraig E O'Suilleabhain
Department of Neurology, The University of Texas Southwestern Medical Center at Dallas, Dallas, TX 75390, USA
Arch Neurol 61:865-8. 2004..An Hcy elevation is prevalent in patients with Parkinson disease (PD) in part because levodopa metabolism produces Hcy. The clinical relevance of an elevated Hcy level in patients with PD is unknown...- Clinical course in Parkinson's disease with elevated homocysteinePadraig E O'Suilleabhain
Department of Neurology, Southwestern Medical Center at Dallas, University of Texas, 5323 Harry Hines Boulevard, Dallas, TX 75390 9036, USA
Parkinsonism Relat Disord 12:103-7. 2006..03). We conclude that hyperhomocysteinemia does not predict significantly worse progression over 2 years in early PD. The data raised the possibility of higher mortality, but the number of deaths was small... - Movement disorders after head injury: diagnosis and managementPadraig O'Suilleabhain
Department of Neurology, University of Texas Southwestern Medical School, Dallas, 75390, USA
J Head Trauma Rehabil 19:305-13. 2004..Reversible causes such as medications or metabolic derangements are occasionally identifiable. Some of these adventitious movements can be improved using neuroactive drugs, botulinum toxin injections, or stereotactic brain surgery... - Tremor response to polarity, voltage, pulsewidth and frequency of thalamic stimulationPadraig E O'Suilleabhain
Department of Neurology, UT Southwestern Medical School, Dallas, TX, USA
Neurology 60:786-90. 2003..The relative impacts of these programmable variables have not previously been quantified... - Contributions of dopaminergic drugs and disease severity to daytime sleepiness in Parkinson diseasePadraig E O'Suilleabhain
Clinical Center for Movement Disorders, Department of Neurology, University of Texas Southwestern Medical School, Dallas, TX, USA
Arch Neurol 59:986-9. 2002..Excessive daytime somnolence is a common report among patients who have Parkinson disease (PD). The relative contributions of disease severity and of the various dopaminergic drugs are unclear... - Randomized trial comparing primidone initiation schedules for treating essential tremorPadraig O'Suilleabhain
Department of Neurology, University of Texas Southwestern Medical Center, Dallas, Texas, USA
Mov Disord 17:382-6. 2002..If anything, compliance tended to be worse when compared with the tablet formulation, though the study was under-powered to reject the null hypothesis of equivalence... - Modest increase in plasma homocysteine follows levodopa initiation in Parkinson's diseasePadraig E O'Suilleabhain
Department of Neurology, University of Texas Southwestern Medical School, Dallas, Texas, USA
Mov Disord 19:1403-8. 2004..Levodopa elevates tHcy and lowers vitamin B12 concentration to modest degrees. The clinical implications, if any, have not yet been determined... 
A stereotactic near-infrared probe for localization during functional neurosurgical procedures: further experienceCole A Giller
Baylor Radiosurgery Center, Baylor University Medical Center, Dallas, TX 75246, USA
J Neurosurg 110:263-73. 2009..In the current study they extend and further validate this technology...- Autonomic dysfunction in Parkinson's diseaseRichard B Dewey
Department of Neurology, University of Texas Southwestern Medical School, 5323 Harry Hines Boulevard, Dallas, TX 75390, USA
Neurol Clin 22:S127-39. 2004 - Medical management of motor fluctuationsRichard B Dewey
University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390 9036, USA
Neurol Clin 26:S15-27, v. 2008..This article briefly reviews the medical options for managing motor fluctuations that are in common use in the United States or that are expected to be available soon... - An unusual variant of the dorsal midbrain syndrome in MS: clinical characteristics and pathophysiologic mechanismsElliot M Frohman
Department of Neurology, University of Texas Southwestern Medical Center at Dallas, Dallas, TX 75390, USA
Mult Scler 10:322-5. 2004..We consider the pathophysiologic mechanisms responsible for our observations and review important details of the dorsal midbrain ocular motor circuitry... - Ventralis intermedius thalamotomy can succeed when ventralis intermedius thalamic stimulation fails: report of 2 cases for tremorCole A Giller
Department of Neurological Surgery and Neurology, University of Texas Southwestern Medical Center, Dallas 75235, USA
Stereotact Funct Neurosurg 79:51-6. 2002..These cases illustrate that the effects of deep brain stimulation might not be those of simple inhibition, and that thalamotomy should be considered when deep brain stimulation does not succeed... - A new measure of dysconjugacy in INO: the first-pass amplitudeElliot M Frohman
Department of Neurology, University of Texas Southwestern Medical Center at Dallas, 5323 Harry Hines Blvd, Dallas, TX 75235, USA
J Neurol Sci 210:65-71. 2003.... - Attitudes and performance of third- vs fourth-year neurology clerkship studentsRichard B Dewey
Department of Neurology, University of Texas Southwestern Medical School, Dallas, TX 75390 9036, USA
Arch Neurol 67:548-51. 2010..To compare student performance, attitudes, and career plans based on whether the neurology clerkship was taken in the third or fourth year... - Cardiac valve regurgitation with pergolide compared with nonergot agonists in Parkinson diseaseRichard B Dewey
Department of Neurology and Division of Cardiology, University of Texas Southwestern Medical Center at Dallas, Dallas, TX 75390 9036, USA
Arch Neurol 64:377-80. 2007.... - Management of motor complications in Parkinson's diseaseRichard B Dewey
Department of Neurology, UT Southwestern Medical Center, University of Texas Southwestern Medical School, 5323 Harry Hines Blvd, Dallas, TX 75390-9036, USA
Neurology 62:S3-7. 2004..The unmet need for treatment of "off" episodes suggests the potential utility of an agent such as apomorphine injectable, which can reliably trigger an "on" response within 10-15 minutes of injection... - Impact of belief in neuroprotection on therapeutic intervention in Parkinson's diseaseRodger J Elble
Department of Neurology, Southern Illinois University School of Medicine, Springfield, Illinois, USA
Mov Disord 25:1082-6. 2010..We found the investigators' level of confidence in these agents had no effect on the time to symptomatic therapy or on the change in UPDRS during 12 months of treatment... - Risk factors for pathologic gambling and other compulsions among Parkinson's disease patients taking dopamine agonistsAsha Singh
Department of Neurology, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, Texas 75390 9036, USA
J Clin Neurosci 14:1178-81. 2007..Follow-up of the pathologic gamblers 1 year after intervention, which was cessation of the dopamine agonist in most cases, found ongoing but controlled gambling in five and complete cessation within 4 months in the remainder... - Adult polyglucosan body disease associated with lewy bodies and tremorJaya R Trivedi
Department of Neurology, University of Texas Southwestern Medical Center, Dallas, 75390, USA
Arch Neurol 60:764-6. 2003..Although polyglucosan bodies were seen in substantia nigra, it is most likely that our patient had coexisting Parkinson disease... - Distinguishing neurogenic from non-neurogenic detrusor overactivity: a urodynamic assessment of lower urinary tract symptoms in patients with and without Parkinson's diseaseGina A Defreitas
Department of Urology, University of Texas Southwestern Medical Center, Dallas, Texas 75390-9110, USA
Urology 62:651-5. 2003..DO owing to Parkinson's disease occurs earlier during filling compared with non-neurogenic DO, especially in women. The duration and severity of Parkinson's disease are not predictive of the nature or severity of UDS abnormalities...