G M Ortiz

Summary

Affiliation: University of California
Country: USA

Publications

  1. pmc Structured antiretroviral treatment interruptions in chronically HIV-1-infected subjects
    G M Ortiz
    Gladstone Institute of Virology and Immunology, University of California, San Francisco, CA 94141 9100, USA
    Proc Natl Acad Sci U S A 98:13288-93. 2001
  2. pmc Residual viral replication during antiretroviral therapy boosts human immunodeficiency virus type 1-specific CD8+ T-cell responses in subjects treated early after infection
    Gabriel M Ortiz
    Aaron Diamond AIDS Research Center, The Rockefeller University, New York, New York 10016, USA
    J Virol 76:411-5. 2002
  3. ncbi request reprint The relationship between T cell proliferative responses and plasma viremia during treatment of human immunodeficiency virus type 1 infection with combination antiretroviral therapy
    J M Binley
    The Aaron Diamond AIDS Research Center, The Rockefeller University, New York, NY 10016, USA
    J Infect Dis 181:1249-63. 2000
  4. ncbi request reprint Emergence of drug-resistant HIV-1 variants in patients undergoing structured treatment interruptions
    Becky Schweighardt
    Gladstone Institute of Virology and Immunology, University of California, San Francisco, CA, USA
    AIDS 16:2342-4. 2002
  5. ncbi request reprint A cytostatic drug improves control of HIV-1 replication during structured treatment interruptions: a randomized study
    Felipe Garcia
    Infectious Diseases Unit, Clinic Institute of Infectious Diseases and Immunology, Institut d Investigacions Biomediques August Pi i Sunyer, Hospital Clinic, Faculty of Medicine, University of Barcelona, Spain
    AIDS 17:43-51. 2003
  6. pmc Dual pressure from antiretroviral therapy and cell-mediated immune response on the human immunodeficiency virus type 1 protease gene
    Annika C Karlsson
    Gladstone Institute of Virology and Immunology, University of California, San Francisco, California 94141, USA
    J Virol 77:6743-52. 2003
  7. ncbi request reprint Changes in CD4+ T-cell differentiation phenotype during structured treatment interruption in patients with chronic HIV-1 infection
    Thomas H Alexander
    Duke University Medical Center, Durham, NC 27705, USA
    J Acquir Immune Defic Syndr 34:475-81. 2003
  8. ncbi request reprint Relevance of HIV-1-specific CD4+ helper T-cell responses during structured treatment interruptions in patients with CD4+ T-cell nadir above 400/mm3
    Montserrat Plana
    Clinic Institute of Infectious Diseases and Immunology, IDIBAPS, Hospital Clinic, Faculty of Medicine, University of Barcelona, Spain
    J Acquir Immune Defic Syndr 36:791-9. 2004

Detail Information

Publications8

  1. pmc Structured antiretroviral treatment interruptions in chronically HIV-1-infected subjects
    G M Ortiz
    Gladstone Institute of Virology and Immunology, University of California, San Francisco, CA 94141 9100, USA
    Proc Natl Acad Sci U S A 98:13288-93. 2001
    ..Despite increases in antiviral immunity, no control of VL was observed. Future studies of STI should proceed with caution...
  2. pmc Residual viral replication during antiretroviral therapy boosts human immunodeficiency virus type 1-specific CD8+ T-cell responses in subjects treated early after infection
    Gabriel M Ortiz
    Aaron Diamond AIDS Research Center, The Rockefeller University, New York, New York 10016, USA
    J Virol 76:411-5. 2002
    ..HIV-1-specific CD8+ T cells can increase in number after HAART in subjects treated early after infection who have episodes of transient viremia...
  3. ncbi request reprint The relationship between T cell proliferative responses and plasma viremia during treatment of human immunodeficiency virus type 1 infection with combination antiretroviral therapy
    J M Binley
    The Aaron Diamond AIDS Research Center, The Rockefeller University, New York, NY 10016, USA
    J Infect Dis 181:1249-63. 2000
    ..Thus, CD4+ T cell responses can sometimes be regenerated if viral load is suppressed to allow some immune recovery and if antigenic stimulation is later provided...
  4. ncbi request reprint Emergence of drug-resistant HIV-1 variants in patients undergoing structured treatment interruptions
    Becky Schweighardt
    Gladstone Institute of Virology and Immunology, University of California, San Francisco, CA, USA
    AIDS 16:2342-4. 2002
    ..We concluded that the repeated abrupt termination and resumption of certain antiretroviral drug regimens during STI therapy may lead to the development of drug resistance in chronically HIV-infected individuals...
  5. ncbi request reprint A cytostatic drug improves control of HIV-1 replication during structured treatment interruptions: a randomized study
    Felipe Garcia
    Infectious Diseases Unit, Clinic Institute of Infectious Diseases and Immunology, Institut d Investigacions Biomediques August Pi i Sunyer, Hospital Clinic, Faculty of Medicine, University of Barcelona, Spain
    AIDS 17:43-51. 2003
    ....
  6. pmc Dual pressure from antiretroviral therapy and cell-mediated immune response on the human immunodeficiency virus type 1 protease gene
    Annika C Karlsson
    Gladstone Institute of Virology and Immunology, University of California, San Francisco, California 94141, USA
    J Virol 77:6743-52. 2003
    ..Our results indicate that both HIV type 1-specific CD8(+) T cells and antiretroviral drugs provide complex pressures on the same amino acid sequence of the HIV protease gene and, thus, can influence viral sequence evolution...
  7. ncbi request reprint Changes in CD4+ T-cell differentiation phenotype during structured treatment interruption in patients with chronic HIV-1 infection
    Thomas H Alexander
    Duke University Medical Center, Durham, NC 27705, USA
    J Acquir Immune Defic Syndr 34:475-81. 2003
    ..These results suggest that interruptions should be avoided whenever possible in patients on HAART with high plasma HIV-1 RNA set-points...
  8. ncbi request reprint Relevance of HIV-1-specific CD4+ helper T-cell responses during structured treatment interruptions in patients with CD4+ T-cell nadir above 400/mm3
    Montserrat Plana
    Clinic Institute of Infectious Diseases and Immunology, IDIBAPS, Hospital Clinic, Faculty of Medicine, University of Barcelona, Spain
    J Acquir Immune Defic Syndr 36:791-9. 2004
    ..To analyze the dynamics of both HIV-1-specific CD4 and CD8 T-cell responses during structured treatment interruptions (STIs) in chronically HIV-1-infected (CHI) patients and to correlate them with the viral set point achieved...