H A Orr

Summary

Affiliation: University of Rochester
Country: USA

Publications

  1. pmc Testing natural selection vs. genetic drift in phenotypic evolution using quantitative trait locus data
    H A Orr
    Department of Biology, University of Rochester, Rochester, New York 14627, USA
    Genetics 149:2099-104. 1998
  2. pmc Genetic analysis of the hybrid male rescue locus of Drosophila
    H A Orr
    Department of Biology, University of Rochester, Rochester, New York 14627, USA
    Genetics 155:225-31. 2000
  3. pmc Haldane's sieve and adaptation from the standing genetic variation
    H A Orr
    Department of Biology, University of Rochester, Rochester, NY 14627, USA
    Genetics 157:875-84. 2001
  4. ncbi request reprint The evolution of postzygotic isolation: accumulating Dobzhansky-Muller incompatibilities
    H A Orr
    Department of Biology, University of Rochester, New York 14627, USA
    Evolution 55:1085-94. 2001
  5. pmc Complex epistasis and the genetic basis of hybrid sterility in the Drosophila pseudoobscura Bogota-USA hybridization
    H A Orr
    Department of Biology, University of Rochester, Rochester, New York 14627, USA
    Genetics 158:1089-100. 2001
  6. ncbi request reprint The evolutionary genetics of adaptation: a simulation study
    H A Orr
    Department of Biology, University of Rochester, NY 14627, USA
    Genet Res 74:207-14. 1999
  7. ncbi request reprint Adaptation and the cost of complexity
    H A Orr
    Department of Biology, University of Rochester, New York 14627, USA
    Evolution 54:13-20. 2000
  8. pmc The rate of adaptation in asexuals
    H A Orr
    Department of Biology, University of Rochester, New York 14627, USA
    Genetics 155:961-8. 2000
  9. pmc Dobzhansky-Muller incompatibilities and adaptation to a shared environment
    R L Unckless
    Department of Biology, University of Rochester, Rochester, NY 14627, USA
    Heredity (Edinb) 102:214-7. 2009
  10. pmc The developmental genetics of hybrid inviability: a mitotic defect in Drosophila hybrids
    H A Orr
    Department of Biology, University of Rochester, NY 14627, USA
    Genetics 145:1031-40. 1997

Detail Information

Publications13

  1. pmc Testing natural selection vs. genetic drift in phenotypic evolution using quantitative trait locus data
    H A Orr
    Department of Biology, University of Rochester, Rochester, New York 14627, USA
    Genetics 149:2099-104. 1998
    ..Rejection of the null hypothesis implies a role for directional natural selection. This test is applicable to any character in any organism in which QTL analysis can be performed...
  2. pmc Genetic analysis of the hybrid male rescue locus of Drosophila
    H A Orr
    Department of Biology, University of Rochester, Rochester, New York 14627, USA
    Genetics 155:225-31. 2000
    ..These findings support previous claims that hybrid embryonic and larval lethalities are genetically distinct and suggest that Hmr(mel) is at least one of the proximate causes of hybrid larval inviability...
  3. pmc Haldane's sieve and adaptation from the standing genetic variation
    H A Orr
    Department of Biology, University of Rochester, Rochester, NY 14627, USA
    Genetics 157:875-84. 2001
    ..autosomal loci. Last, we suggest a test to determine whether adaptation used new mutations or previously deleterious alleles from the standing genetic variation...
  4. ncbi request reprint The evolution of postzygotic isolation: accumulating Dobzhansky-Muller incompatibilities
    H A Orr
    Department of Biology, University of Rochester, New York 14627, USA
    Evolution 55:1085-94. 2001
    ..Our analyses of data from Drosophila and Bombina suggest that p is generally very small, on the order of 10(-6) or less...
  5. pmc Complex epistasis and the genetic basis of hybrid sterility in the Drosophila pseudoobscura Bogota-USA hybridization
    H A Orr
    Department of Biology, University of Rochester, Rochester, New York 14627, USA
    Genetics 158:1089-100. 2001
    ..Indeed, a maximum likelihood analysis suggests that roughly 15 hybrid male steriles separate the Bogota and USA subspecies. Only a subset of these would act in F1 hybrids...
  6. ncbi request reprint The evolutionary genetics of adaptation: a simulation study
    H A Orr
    Department of Biology, University of Rochester, NY 14627, USA
    Genet Res 74:207-14. 1999
    ..The results show that adaptation towards a fixed optimum is generally characterized by an exponential effects trend...
  7. ncbi request reprint Adaptation and the cost of complexity
    H A Orr
    Department of Biology, University of Rochester, New York 14627, USA
    Evolution 54:13-20. 2000
    ..The present results also suggest that one can define an effective number of dimensions characterizing an adapting species...
  8. pmc The rate of adaptation in asexuals
    H A Orr
    Department of Biology, University of Rochester, New York 14627, USA
    Genetics 155:961-8. 2000
    ..In the course of this work, I derive an approximation to the probability of fixation of a favorable mutation in an asexual genome or nonrecombining chromosome region in which both favorable and deleterious mutations occur...
  9. pmc Dobzhansky-Muller incompatibilities and adaptation to a shared environment
    R L Unckless
    Department of Biology, University of Rochester, Rochester, NY 14627, USA
    Heredity (Edinb) 102:214-7. 2009
    ..This precludes the development of a DMI, which requires different substitutions in the two populations...
  10. pmc The developmental genetics of hybrid inviability: a mitotic defect in Drosophila hybrids
    H A Orr
    Department of Biology, University of Rochester, NY 14627, USA
    Genetics 145:1031-40. 1997
    ..melanogaster and autosomal gene(s) from D. melanogaster's sister species...
  11. ncbi request reprint The unexpected recovery of hybrids in a Drosophila species cross: a genetic analysis
    H A Orr
    Department of Biology, University of Rochester, NY 14627, USA
    Genet Res 67:11-8. 1996
    ..melanogaster males. Genetic analysis of the difference between D. simulans strains that produce many versus few hybrid females shows that recovery of hybrid females depends on autosomal, maternally acting gene(s)...
  12. ncbi request reprint Mapping and characterization of a 'speciation gene' in Drosophila
    H A Orr
    Center for Population Biology, University of California, Davis 95616
    Genet Res 59:73-80. 1992
    ..Hms is zygotically acting, and the D. simulans allele of hms is completely recessive. Furthermore, complementation tests suggest that hms is not an allele of any known locus in D. melanogaster...
  13. pmc Does hybrid lethality depend on sex or genotype?
    H A Orr
    Genetics 152:1767-9. 1999