Genomes and Genes
PETER AB ORLEAN
Affiliation: University of Illinois
- Gpi1, a Saccharomyces cerevisiae protein that participates in the first step in glycosylphosphatidylinositol anchor synthesisS D Leidich
Department of Biochemistry, University of Illinois at Urbana Champaign, Urbana, Illinois 61801, USA
J Biol Chem 271:27829-37. 1996..These findings indicate that GPIs have key roles in the morphogenesis and development of S. cerevisiae...
- Thematic review series: lipid posttranslational modifications. GPI anchoring of protein in yeast and mammalian cells, or: how we learned to stop worrying and love glycophospholipidsPeter Orlean
Department of Microbiology, University of Illinois at Urbana Champaign, Urbana, IL 61801, USA
J Lipid Res 48:993-1011. 2007..GPI biosynthesis is essential for viability in yeast and for embryonic development in mammals. In this review, we describe the biosynthesis of mammalian and yeast GPIs, their transfer to protein, and their subsequent processing...
- GLYCOLIPID ANCHORS AND GLUCOSAMINE SACCHARIDES IN YEASTSPeter Orlean; Fiscal Year: 1999..The consequences of reduced or excessive expression of SpChs1 on growth of fission yeast should provide clues as to how chitin synthase-like proteins and their product function in vertebrate embryogenesis. ..
- GLYCOLIPID ANCHORING AND O-GLYCOSYLATION IN YEASTPeter Orlean; Fiscal Year: 1993..These studies will allow evaluation of O- mannosylation as a potential target for the selective action of an antifungal agent...
- PATHWAYS FOR GLYCOSYLPHOSPHATIDYLINOSITOL ASSEMBLYPeter Orlean; Fiscal Year: 2003..Detailed searches of genome sequence databases have also identified genes encoding candidate GPI synthetic enzymes, whose role in GPI assembly will be explored by creating yeast mutants in them. ..