Research Topics
| John P O'ReardonSummaryAffiliation: University of Pennsylvania Country: USA Publications
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Publications
A randomized, placebo-controlled trial of sertraline in the treatment of night eating syndromeJohn P O'Reardon
Department of Psychiatry, University of Pennsylvania, Rm 4005, 3535 Market St, Philadelphia, PA 19104, USA
Am J Psychiatry 163:893-8. 2006..The authors assessed the efficacy of sertraline in the treatment of night eating syndrome...
Acute coronary syndrome (Takotsubo cardiomyopathy) following electroconvulsive therapy in the absence of significant coronary artery disease: case report and review of the literatureJohn P O'Reardon
ECT Service, Department of Psychiatry, University of Pennsylvania School of Medicine, Philadelphia, PA, USA
J ECT 24:277-80. 2008..This case illustrates the importance of careful workup of chest pain in the setting of ECT, even if electrocardiogram findings seem unremarkable initially...
Electroconvulsive therapy in a 96-year-old patient with severe aortic stenosis: a case report and review of the literatureJohn P O'Reardon
ECT Service, Department of Psychiatry, University of Pennsylvania School of Medicine, Philadelphia, PA, USA
J ECT 24:96-8. 2008..This case illustrates that neither age nor aortic stenosis by itself precludes ECT in the setting of severe depression. Rather, in each case, a careful weighing of the risks both of proceeding with and withholding ECT is warranted...
Unexpected reduction in migraine and psychogenic headaches following rTMS treatment for major depression: a report of two casesJohn P O'Reardon
University of Pennsylvania, Transcranial Magnetic Stimulation Laboratory, Philadelphia, PA, USA
CNS Spectr 12:921-5. 2007..In these subjects, rTMS was, in fact, associated with relief of depressive symptoms and preexisting headache pain. This indicates that rTMS may be beneficial for both disorders in some patients...
Propofol for the management of emergence agitation after electroconvulsive therapy: review of a case seriesJohn P O'Reardon
ECT Service and Training Program, Department of Psychiatry, Hospital of the University of Pennsylvania, Philadelphia, PA, USA
J ECT 22:247-52. 2006..Although further study is needed, these results suggest that propofol may be a very valuable additional agent for the ECT clinician in the management of PIA, which is a common entity in the setting of ECT...
Patients with a major depressive episode responding to treatment with repetitive transcranial magnetic stimulation (rTMS) are resistant to the effects of rapid tryptophan depletionJohn P O'Reardon
Laboratory for Transcranial Magnetic Stimulation, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
Depress Anxiety 24:537-44. 2007..Responders to rTMS are resistant to the mood perturbing effects of RTD. This suggests that rTMS does not depend on the central availability of serotonin to exert antidepressant effects in major depression...
Acute and maintenance electroconvulsive therapy for treatment of severe major depression during the second and third trimesters of pregnancy with infant follow-up to 18 months: case report and review of the literatureJohn P O'Reardon
ECT Service, Department of Psychiatry, University of Pennsylvania School of Medicine, Philadelphia, PA USA
J ECT 27:e23-6. 2011..Development of the child has been assessed as fully normal in all follow-up visits with the pediatrician out to 18 months...
Long-term maintenance therapy for major depressive disorder with rTMSJohn P O'Reardon
Department of Psychiatry, University of Pennsylvania, Ste 4005, 3535 Market Street, Philadelphia, PA 19104, USA
J Clin Psychiatry 66:1524-8. 2005..We describe long-term maintenance therapy for major depressive disorder with rTMS...
Night eating syndrome : diagnosis, epidemiology and managementJohn P O'Reardon
Division of Mood and Anxiety Disorders, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA
CNS Drugs 19:997-1008. 2005..One clinical trial has reported efficacy with the SSRI sertraline. Other treatments, such as the anticonvulsant topiramate, phototherapy and other SSRIs, may also offer future promise...
Clinical trial of sertraline in the treatment of night eating syndromeJohn P O'Reardon
Department of Psychiatry, Weight and Eating Disorders Program, University of Pennsylvania, Philadelphia, 19104, USA
Int J Eat Disord 35:16-26. 2004..To test the efficacy of sertraline in the treatment of night eating syndrome...
Circadian rhythm profiles in women with night eating syndromeNamni Goel
University of Pennsylvania School of Medicine, Philadelphia, PA, USA
J Biol Rhythms 24:85-94. 2009..Indeed, bright light therapy has shown efficacy in reducing night eating in case studies and should be evaluated in controlled clinical trials...
Cognitive behavior therapy for night eating syndrome: a pilot studyKelly C Allison
Department of Psychiatry, University of Pennsylvania School of Medicine, 3535 Market Street, 3rd Floor, Philadelphia, PA 19104 3309, USA
Am J Psychother 64:91-106. 2010..02). This first clinical trial of CBT for NES shows significant improvements in the core aspects of NES and weight reduction, suggesting the need for a controlled treatment trial...
A paradigm for facilitating pharmacotherapy at a distance: sertraline treatment of the night eating syndromeAlbert J Stunkard
Department of Psychiatry Weight and Eating Disorders Program, University of Pennsylvania School of Medicine, Philadelphia, USA
J Clin Psychiatry 67:1568-72. 2006..To test a novel method of facilitating pharmacotherapy at a distance and assess the effectiveness of sertraline for the treatment of night eating syndrome (NES)...
A descriptive study of non-obese persons with night eating syndrome and a weight-matched comparison groupJennifer D Lundgren
University of Pennsylvania School of Medicine, 3535 Market Street, Philadelphia, PA 19104, USA
Eat Behav 9:343-51. 2008....
Development of criteria for a diagnosis: lessons from the night eating syndromeAlbert J Stunkard
Department of Psychiatry, Center for Weight and Eating Disorders, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
Compr Psychiatry 50:391-9. 2009..In conclusion, research on NES supports the validity of the diagnosis and its inclusion in DSM-V...
The Night Eating Questionnaire (NEQ): psychometric properties of a measure of severity of the Night Eating SyndromeKelly C Allison
University of Pennsylvania School of Medicine Center for Weight and Eating Disorders, 3535 Market Street, Ste 3021, Philadelphia, PA 19104 3309, United States
Eat Behav 9:62-72. 2008..Study 3 compared scores from obese bariatric surgery candidates with and without NES and found appropriate discriminant validity of the NEQ. The NEQ appears to be an efficient, valid measure of severity for NES...
Proposed diagnostic criteria for night eating syndromeKelly C Allison
Department of Psychiatry, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104 3309, USA
Int J Eat Disord 43:241-7. 2010..To propose criteria for diagnosis of the night eating syndrome (NES)...
Prevalence of the night eating syndrome in a psychiatric populationJennifer D Lundgren
Department of Psychiatry Weight and Eating Disorders Program, University of Pennsylvania, 3535 Market St, Suite 3123, Philadelphia, PA 19104 3309, USA
Am J Psychiatry 163:156-8. 2006..This study assessed the prevalence of night eating syndrome and its comorbid psychopathology in a psychiatric population...
Evaluation of diagnostic criteria for night eating syndrome using item response theory analysisKelly C Allison
University of Pennsylvania School of Medicine, Department of Psychiatry, Center for Weight and Eating Disorders, 3535 Market St, 3rd Floor, Philadelphia, PA 19104 3309, USA
Eat Behav 9:398-407. 2008..Behavioral factors were identified as useful discriminators of NES. Future work should also examine psychological factors in conjunction with those identified here...
Cognitive therapy vs medications in the treatment of moderate to severe depressionRobert J Derubeis
Department of Psychology, University of Pennsylvania, Philadelphia, PA 19104, USA
Arch Gen Psychiatry 62:409-16. 2005..There is substantial evidence that antidepressant medications treat moderate to severe depression effectively, but there is less data on cognitive therapy's effects in this population...
Pregnancy and depression: exploring a new potential treatment optionDeborah R Kim
Perinatal Psychiatry Clinic, Department of Psychiatry, University of Pennsylvania, 3535 Market Street, 2nd Floor, Philadelphia, PA 19104, USA
Curr Psychiatry Rep 11:443-6. 2009..In this article, we propose that a novel device technology known as repetitive transcranial magnetic stimulation should be systematically studied as a potential treatment option for women with major depressive disorder during pregnancy...
Effectiveness and safety of vagus nerve stimulation for severe treatment-resistant major depression in clinical practice after FDA approval: outcomes at 1 yearPilar Cristancho
Mood and Anxiety Disorders Treatment and Research Program, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
J Clin Psychiatry 72:1376-82. 2011..To describe the outcomes of a consecutive series of depressed patients treated with vagus nerve stimulation (VNS) following US Food and Drug Administration (FDA) approval of this intervention...
Transcranial magnetic stimulation (TMS) in the treatment of attention-deficit/hyperactivity disorder in adolescents and young adults: a pilot studyLaurel Weaver
TMS Treatment and Research Program, Department of Psychiatry, University of Pennsylvania, Philadelphia, PA 19104, USA
J ECT 28:98-103. 2012..We tested its safety and efficacy in young persons with a diagnosis of attention-deficit/hyperactivity disorder (ADHD)...
The night eating syndrome: a progress reportAlbert J Stunkard
Weight and Eating Disorders Program, Department of Psychiatry, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
Appetite 45:182-6. 2005..A case study and an open-label trial with SSRIs suggest that they may treat NES effectively. Randomized controlled trials are needed...
Neuroendocrine profiles associated with energy intake, sleep, and stress in the night eating syndromeKelly C Allison
University of Pennsylvania School of Medicine, Department of Psychiatry, Weight and Eating Disorders Program, 3535 Market Street, Suite 3021, Philadelphia, Pennsylvania 19104, USA
J Clin Endocrinol Metab 90:6214-7. 2005..Night eating syndrome (NES) is characterized by evening hyperphagia and frequent awakenings with ingestion of food. It is associated with obesity and depressed mood. Greater understanding of hormonal influences on NES is desirable...
Effectiveness of transcranial magnetic stimulation in clinical practice post-FDA approval in the United States: results observed with the first 100 consecutive cases of depression at an academic medical centerK Ryan Connolly
Philadelphia VA Medical Center, Department of Behavioral Health, Philadelphia, PA 19104, USA
J Clin Psychiatry 73:e567-73. 2012....
Guidelines for the management of depression during pregnancyDeborah R Kim
Department of Psychiatry, University of Pennsylvania, 3535 Market Street, 2nd Floor, Philadelphia, PA 19104, USA
Curr Psychiatry Rep 12:279-81. 2010..Guidelines regarding the treatment of depression during pregnancy were recently published by the American Psychiatric Association and the American College of Obstetricians and Gynecologists. We provide a commentary on these guidelines...
A case of delayed onset of threatened premature labor in association with electroconvulsive therapy in the third trimester of pregnancyAngeliki Pesiridou
ECT Service, Department of Psychiatry, University of Pennsylvania, Philadelphia, PA, USA
J ECT 26:228-30. 2010..Patients and treatment team need to be aware of this possibility, particularly when ECT is conducted on an outpatient basis...
Clinical approach to agitation after electroconvulsive therapy: a case report and literature reviewJohn G Augoustides
Department of Anesthesia, University of Pennsylvania, PA 19104 4283, USA
J ECT 18:213-7. 2002..The clinical management of this challenging presentation is discussed, including both the anesthetic and psychiatric approaches...
Uncommon but serious complications associated with electroconvulsive therapy: recognition and management for the clinicianMario A Cristancho
Department of Psychiatry, University of Pennsylvania, 3535 Market Street, 2nd Floor, Philadelphia, PA 19104, USA
Curr Psychiatry Rep 10:474-80. 2008..Understanding such complications and their management strategies avoids unnecessary treatment discontinuation due to manageable ECT complications...
A survey of patient acceptability of repetitive transcranial magnetic stimulation (TMS) during pregnancyDeborah R Kim
Department of Psychiatry, University of Pennsylvania, Philadelphia, PA 19104, United States
J Affect Disord 129:385-90. 2011..Given the novelty of TMS, we sought to assess whether patient acceptability would be a barrier to enrolling pregnant women in TMS studies...
Customized anesthetic preservation of ictal threshold in electroconvulsive therapy: role of adjunctive remifentanil with etomidateJohn G Augoustides
Department of Anesthesia Cardiothoracic Section, Hospital of University of Pennsylvania, Philadelphia, PA 19104 4283, USA
J ECT 21:128-31. 2005..Anesthesiologists should be aware of factors influencing the seizure duration and, keeping in mind the coexisting medical conditions of the patient, adjustments should be made to get the best possible outcome...
An open label pilot study of transcranial magnetic stimulation for pregnant women with major depressive disorderDeborah R Kim
Department of Psychiatry, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
J Womens Health (Larchmt) 20:255-61. 2011..We present the results of an open label pilot study examining treatment with transcranial magnetic stimulation (TMS) in pregnant women with MDD...
Electroconvulsive therapy for treatment of major depression in a 100-year-old patient with severe aortic stenosis: a 5-year follow-up reportJohn P O'Reardon
ECT Service, Department of Psychiatry, University of Pennsylvania School of Medicine, Philadelphia, PA, USA
J ECT 27:227-30. 2011..Each case needs to be evaluated on its merits. To our knowledge, this case represents the oldest patient in the literature where ECT has been administered safely for such an extended period in the setting of severe aortic stenosis...
Pharmacologic and therapeutic strategies in treatment-resistant depression. Introduction and clinical presentationsJohn P O'Reardon
Treatment Resistant Depression Clinic, University of Pennsylvania, Philadelphia, USA
CNS Spectr 14:4-6. 2009
Efficacy of duloxetine for the treatment of depression: relationship to most recent antidepressant trialTimothy Petersen
Department of Psychiatry, Massachusetts General Hospital, Boston, MA, USA
Psychopharmacol Bull 41:34-45. 2008..To describe and examine, in a sample of depressed outpatients, the relationship between level of response to a previous SSRI or SNRI antidepressant trial and subsequent response to duloxetine hydrochloride...
Neonatal outcomes with the use of lamotrigine for bipolar disorder in pregnancy and breastfeeding: a case series and review of the literatureLaura Wakil
Department of Psychiatry, University of Pennsylvania, Philadelphia, PA, USA
Psychopharmacol Bull 42:91-8. 2009..We present three cases of women exposed to lamotrigine during pregnancy and breastfeeding, with follow up of their infants until 15-18 months of development...
Transcranial magnetic stimulation in the treatment of major depressive disorder: a comprehensive summary of safety experience from acute exposure, extended exposure, and during reintroduction treatmentPhilip G Janicak
Department of Psychiatry, Rush University Medical Center, Chicago, IL 60612, USA
J Clin Psychiatry 69:222-32. 2008..We examined the acute efficacy of TMS in a randomized sham-controlled trial, under open-label conditions, and its durability of benefit...
Transcranial magnetic stimulation in the treatment of psychiatric disordersDeborah R Kim
Perinatal Psychiatry Clinic, Department of Psychiatry, University of Pennsylvania, 3535 Market Street, 2nd Floor, Philadelphia, PA 19104, USA
Curr Psychiatry Rep 11:447-52. 2009..In this article, we describe TMS and its neurobiologic basis, as well as the efficacy and safety data of TMS with regard to a range of psychiatric disorders...
Durability of clinical benefit with transcranial magnetic stimulation (TMS) in the treatment of pharmacoresistant major depression: assessment of relapse during a 6-month, multisite, open-label studyPhilip G Janicak
Department of Psychiatry, Rush University Medical Center, Chicago, Illinois 60612, USA
Brain Stimul 3:187-99. 2010..Although transcranial magnetic stimulation (TMS) can be an effective acute antidepressant treatment, few studies systematically examine persistence of benefit...
Transcranial magnetic stimulation: a device intended for the psychiatrist's office, but what is its future clinical role?Dhwani B Shah
TMS Laboratory, Philadelphia, PA 19104, USA
Expert Rev Med Devices 5:559-66. 2008..TMS is a promising form of neuromodulation therapy that will most likely become a significant part of clinical practice in the future...
Rethinking the treatment paradigm for bipolar depression: the importance of long-term managementClaudia F Baldassano
Department of Psychiatry, University of Pennsylvania Medical Center, Philadelphia, PA 19104, USA
CNS Spectr 9:11-8. 2004..To date, three agents--lithium, lamotrigine, and olanzapine--have been shown to have prophylactic benefits in treating this highly recurrent disorder...
