Trevor J Orchard

Summary

Affiliation: University of Pittsburgh
Country: USA

Publications

  1. pmc Haptoglobin genotype and the rate of renal function decline in the diabetes control and complications trial/epidemiology of diabetes interventions and complications study
    Trevor J Orchard
    Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
    Diabetes 62:3218-23. 2013
  2. pmc The association of skin intrinsic fluorescence with type 1 diabetes complications in the DCCT/EDIC study
    Trevor J Orchard
    Corresponding author Trevor J Orchard
    Diabetes Care 36:3146-53. 2013
  3. pmc In the absence of renal disease, 20 year mortality risk in type 1 diabetes is comparable to that of the general population: a report from the Pittsburgh Epidemiology of Diabetes Complications Study
    T J Orchard
    Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA 15213, USA
    Diabetologia 53:2312-9. 2010
  4. ncbi request reprint Type 1 diabetes and coronary artery disease
    Trevor J Orchard
    MBBCh, MMedSci, Diabetes and Lipid Research Bldg, 3512 Fifth Ave, Pittsburgh, PA 15213, USA
    Diabetes Care 29:2528-38. 2006
  5. ncbi request reprint Nephropathy in type 1 diabetes: a manifestation of insulin resistance and multiple genetic susceptibilities? Further evidence from the Pittsburgh Epidemiology of Diabetes Complication Study
    Trevor J Orchard
    Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, DLR Building, 35123 Fifth Avenue, Pittsburgh, PA 15213, USA
    Kidney Int 62:963-70. 2002
  6. ncbi request reprint Lipid and blood pressure treatment goals for type 1 diabetes: 10-year incidence data from the Pittsburgh Epidemiology of Diabetes Complications Study
    T J Orchard
    Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, 3512 Fifth Avenue, Pittsburgh, PA 15213, USA
    Diabetes Care 24:1053-9. 2001
  7. pmc Augmentation pressure and subendocardial viability ratio are associated with microalbuminuria and with poor renal function in type 1 diabetes
    Catherine T Prince
    Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, 3512 Fifth Avenue, Pittsburgh, PA 15213, USA
    Diab Vasc Dis Res 7:216-24. 2010
  8. pmc Haptoglobin genotype and renal function decline in type 1 diabetes
    Tina Costacou
    Department of Epidemiology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
    Diabetes 58:2904-9. 2009
  9. pmc Cause-specific mortality trends in a large population-based cohort with long-standing childhood-onset type 1 diabetes
    Aaron M Secrest
    Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
    Diabetes 59:3216-22. 2010
  10. ncbi request reprint Novel predictors of overt nephropathy in subjects with type 1 diabetes. A nested case control study from the Pittsburgh Epidemiology of Diabetes Complications cohort
    Aklilu A Yishak
    Department of Medicine, University of Pittsburgh School of Medicine, and Veterans Pittsburgh Health Care System of Pittsburgh, Pittsburgh, PA 15213, USA
    Nephrol Dial Transplant 21:93-100. 2006

Research Grants

  1. EPIDEMIOLOGY OF DIABETIC COMPLICATIONS--PHASE II
    Trevor Orchard; Fiscal Year: 2001
  2. EPIDEMIOLOGY OF DIABETIC COMPLICATIONS--PHASE II
    Trevor Orchard; Fiscal Year: 2002
  3. EPIDEMIOLOGY OF DIABETIC COMPLICATIONS--PHASE II
    Trevor Orchard; Fiscal Year: 2002
  4. EPIDEMIOLOGY OF DIABETIC COMPLICATIONS--PHASE II
    Trevor Orchard; Fiscal Year: 2003
  5. EPIDEMIOLOGY OF DIABETIC COMPLICATIONS--PHASE II
    Trevor Orchard; Fiscal Year: 2003
  6. Epidemiology of Diabetes Complication:Phase II
    Trevor Orchard; Fiscal Year: 2004
  7. Progression of Cardiovascular Disease in TID: CADRE/EDC
    Trevor Orchard; Fiscal Year: 2004
  8. Epidemiology of Diabetes Complication:Phase II
    Trevor Orchard; Fiscal Year: 2005
  9. Progression of Cardiovascular Disease in TID: CADRE/EDC
    Trevor Orchard; Fiscal Year: 2005
  10. Epidemiology of Diabetes Complication:Phase II
    Trevor Orchard; Fiscal Year: 2006

Detail Information

Publications105 found, 100 shown here

  1. pmc Haptoglobin genotype and the rate of renal function decline in the diabetes control and complications trial/epidemiology of diabetes interventions and complications study
    Trevor J Orchard
    Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
    Diabetes 62:3218-23. 2013
    ..We conclude that the HP genotype is significantly associated with the development of reduced GFR and ESRD in the DCCT/EDIC study. ..
  2. pmc The association of skin intrinsic fluorescence with type 1 diabetes complications in the DCCT/EDIC study
    Trevor J Orchard
    Corresponding author Trevor J Orchard
    Diabetes Care 36:3146-53. 2013
    ..To determine whether skin intrinsic fluorescence (SIF) is associated with long-term complications of type 1 diabetes (T1D) and, if so, whether it is independent of chronic glycemic exposure and previous intensive therapy...
  3. pmc In the absence of renal disease, 20 year mortality risk in type 1 diabetes is comparable to that of the general population: a report from the Pittsburgh Epidemiology of Diabetes Complications Study
    T J Orchard
    Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA 15213, USA
    Diabetologia 53:2312-9. 2010
    ....
  4. ncbi request reprint Type 1 diabetes and coronary artery disease
    Trevor J Orchard
    MBBCh, MMedSci, Diabetes and Lipid Research Bldg, 3512 Fifth Ave, Pittsburgh, PA 15213, USA
    Diabetes Care 29:2528-38. 2006
  5. ncbi request reprint Nephropathy in type 1 diabetes: a manifestation of insulin resistance and multiple genetic susceptibilities? Further evidence from the Pittsburgh Epidemiology of Diabetes Complication Study
    Trevor J Orchard
    Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, DLR Building, 35123 Fifth Avenue, Pittsburgh, PA 15213, USA
    Kidney Int 62:963-70. 2002
    ..The pathogenesis of diabetic nephropathy remains unclear, although previous reports implicate a wide range of putative genetic and metabolic factors...
  6. ncbi request reprint Lipid and blood pressure treatment goals for type 1 diabetes: 10-year incidence data from the Pittsburgh Epidemiology of Diabetes Complications Study
    T J Orchard
    Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, 3512 Fifth Avenue, Pittsburgh, PA 15213, USA
    Diabetes Care 24:1053-9. 2001
    ..The objective of this study was to determine at which levels of LDL and HDL cholesterol, triglycerides, and blood pressure the relative risks of type 1 diabetic complications increase significantly...
  7. pmc Augmentation pressure and subendocardial viability ratio are associated with microalbuminuria and with poor renal function in type 1 diabetes
    Catherine T Prince
    Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, 3512 Fifth Avenue, Pittsburgh, PA 15213, USA
    Diab Vasc Dis Res 7:216-24. 2010
    ....
  8. pmc Haptoglobin genotype and renal function decline in type 1 diabetes
    Tina Costacou
    Department of Epidemiology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
    Diabetes 58:2904-9. 2009
    ....
  9. pmc Cause-specific mortality trends in a large population-based cohort with long-standing childhood-onset type 1 diabetes
    Aaron M Secrest
    Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
    Diabetes 59:3216-22. 2010
    ..Little is known concerning the primary cause(s) of mortality in type 1 diabetes responsible for the excess mortality seen in this population...
  10. ncbi request reprint Novel predictors of overt nephropathy in subjects with type 1 diabetes. A nested case control study from the Pittsburgh Epidemiology of Diabetes Complications cohort
    Aklilu A Yishak
    Department of Medicine, University of Pittsburgh School of Medicine, and Veterans Pittsburgh Health Care System of Pittsburgh, Pittsburgh, PA 15213, USA
    Nephrol Dial Transplant 21:93-100. 2006
    ..Predictors of diabetic nephropathy are only partly known and traditional risk factors do not adequately explain disease risk. We thus examined novel risk factors for overt nephropathy (ON) in type 1 diabetes...
  11. pmc Are hemoglobin levels elevated in type 1 diabetes?
    Baqiyyah N Conway
    Department of Epidemiology, University of Pittsburgh, Pittsburgh, Pennsylvantia, USA
    Diabetes Care 33:341-3. 2010
    ..8 g/dl. We thus explored whether hemoglobin concentrations are generally higher in type 1 diabetes...
  12. pmc Sex differences in the development of kidney disease in individuals with type 1 diabetes mellitus: a contemporary analysis
    Tina Costacou
    Department of Epidemiology, University of Pittsburgh, PA, USA
    Am J Kidney Dis 58:565-73. 2011
    ..Kidney disease in patients with type 1 diabetes historically has been believed to be more prevalent in men. Because recent data do not reflect this pattern, we evaluated whether a sex difference persists...
  13. doi request reprint Haptoglobin genotype: a determinant of cardiovascular complication risk in type 1 diabetes
    Tina Costacou
    Department of Epidemiology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
    Diabetes 57:1702-6. 2008
    ..We investigated the association between the haptoglobin genotype and the incidence of coronary artery disease (CAD) in a cohort of individuals with childhood-onset type 1 diabetes...
  14. pmc Prediction of proliferative diabetic retinopathy with hemoglobin level
    Baqiyyah N Conway
    University of Pittsburgh, Pittsburgh, Pennsylvania 15213, USA
    Arch Ophthalmol 127:1494-9. 2009
    ..To investigate the role of hemoglobin (HGB) level in predicting proliferative diabetic retinopathy (PDR)...
  15. ncbi request reprint The 30-year natural history of type 1 diabetes complications: the Pittsburgh Epidemiology of Diabetes Complications Study experience
    Georgia Pambianco
    Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Diabetes and Lipid Research Building, 3512 Fifth Avenue, Pittsburgh, PA 15213, USA
    Diabetes 55:1463-9. 2006
    ..Although some type 1 diabetes complications (mortality, renal failure, and neuropathy) are declining, others (CAD, overt nephropathy, and proliferative retinopathy) show less favorable changes by 30 years...
  16. ncbi request reprint Identifying genetic susceptibilities to diabetes-related complications among individuals at low risk of complications: An application of tree-structured survival analysis
    Tina Costacou
    Department of Epidemiology, University of Pittsburgh, Pittsburgh, PA, USA
    Am J Epidemiol 164:862-72. 2006
    ..05). Tree-structured survival analysis may help identify genetic predispositions among individuals who, despite low risk, develop diabetes-related complications...
  17. ncbi request reprint Sequence of progression of albuminuria and decreased GFR in persons with type 1 diabetes: a cohort study
    Tina Costacou
    Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA 15213, USA
    Am J Kidney Dis 50:721-32. 2007
    ..We determined the sequence of kidney disease stages (microalbuminuria, macroalbuminuria, low estimated glomerular filtration rate [eGFR], and end-stage renal disease [ESRD]) and characterized those without albuminuria before a low eGFR...
  18. pmc Lipoprotein-associated phospholipase A2, C-reactive protein, and coronary artery disease in individuals with type 1 diabetes and macroalbuminuria
    Rachel G Miller
    University of Pittsburgh, Department of Epidemiology, Graduate School of Public Health, Pittsburgh, PA, USA
    Diab Vasc Dis Res 7:47-55. 2010
    ..40, p=0.05), but not 2/2 (HR=0.66, p=0.27), genotype. The association between Lp-PLA(2) activity and CAD differs by CRP and haptoglobin genotype in this group of persons with type 1 diabetes and macroalbuminuria...
  19. doi request reprint Translating the Diabetes Prevention Program: a comprehensive model for prevention training and program delivery
    M Kaye Kramer
    Department of Epidemiology, University of Pittsburgh Graduate School of Public Health, Pittsburgh, Pennsylvania 15213, USA
    Am J Prev Med 37:505-11. 2009
    ..A universal framework for translation of multiple aspects of the DPP intervention, including training, support, and evaluation is needed to enhance treatment fidelity in a variety of settings...
  20. ncbi request reprint Insulin resistance-related factors, but not glycemia, predict coronary artery disease in type 1 diabetes: 10-year follow-up data from the Pittsburgh Epidemiology of Diabetes Complications Study
    Trevor J Orchard
    Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pennsylvania, USA
    Diabetes Care 26:1374-9. 2003
    ..To determine the independent risk factors for coronary artery disease (CAD) in type 1 diabetes by type of CAD at first presentation...
  21. pmc Progression of coronary artery calcium in type 1 diabetes mellitus
    Tina Costacou
    Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
    Am J Cardiol 100:1543-7. 2007
    ..Thus, weight control, in addition to lipid and renal management, may help retard atherosclerosis progression in persons with type 1 DM...
  22. pmc All-cause mortality trends in a large population-based cohort with long-standing childhood-onset type 1 diabetes: the Allegheny County type 1 diabetes registry
    Aaron M Secrest
    Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
    Diabetes Care 33:2573-9. 2010
    ..Although management of type 1 diabetes improved dramatically in the 1980s, the effect on mortality is not clear...
  23. pmc Associations between socioeconomic status and major complications in type 1 diabetes: the Pittsburgh epidemiology of diabetes complication (EDC) Study
    Aaron M Secrest
    Department of Epidemiology, University of Pittsburgh, Pittsburgh, PA 15213, USA
    Ann Epidemiol 21:374-81. 2011
    ..To understand the effect of socioeconomic status (SES) on the risk of complications in type 1 diabetes (T1D), we explored the relationship between SES and major diabetes complications in a prospective, observational T1D cohort study...
  24. pmc Pulse wave analysis and cardiac autonomic neuropathy in type 1 diabetes: a report from the Pittsburgh Epidemiology of Diabetes Complications Study
    Aaron M Secrest
    Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, 3512 Fifth Avenue, Pittsburgh, PA 15213, USA
    Diabetes Technol Ther 13:1264-8. 2011
    ....
  25. ncbi request reprint Markers of endothelial dysfunction in the prediction of coronary artery disease in type 1 diabetes. The Pittsburgh Epidemiology of Diabetes Complications Study
    Tina Costacou
    Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA, USA
    J Diabetes Complications 19:183-93. 2005
    ..13, 95% Cl=1.03-1.24; HRs are per standard deviation increase) but not hard CAD. Study results suggest that E-selectin may enhance CAD prediction beyond traditional risk factors or markers of oxidative stress in Type 1 diabetes...
  26. pmc Pulse wave analysis and prevalent cardiovascular disease in type 1 diabetes
    Catherine T Prince
    Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA, United States
    Atherosclerosis 213:469-74. 2010
    ..Pulse wave analysis (PWA) arterial stiffness indices have been associated with cardiovascular disease (CVD) risk factors and outcomes in various populations, but little is known regarding these relationships in T1D...
  27. ncbi request reprint Influences on screening for chronic diabetes complications in type 1 diabetes
    Rashida R Dorsey
    Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
    Dis Manag 9:93-101. 2006
    ..Our data indicate that efforts to rectify this should focus on men and those who do not monitor blood glucose, and should involve primary care practitioners...
  28. ncbi request reprint Double-edged relationship between adiposity and coronary artery calcification in type 1 diabetes
    Baqiyyah Conway
    Department of Epidemiology, Graduate School of Public Health, The University of Pittsburgh, Pittsburgh, PA 15217, USA
    Diab Vasc Dis Res 4:332-9. 2007
    ..This double-edged association emphasises the complex relationship between adiposity and cardiovascular risk in diabetes...
  29. doi request reprint Impact of patient level factors on the improvement of the ABCs of diabetes
    Gretchen A Piatt
    Division of Endocrinology and Metabolism, University of Pittsburgh, PA, USA
    Patient Educ Couns 82:266-70. 2011
    ..To determine which patient factors contribute to improvements in the ABCs of diabetes following a multi-faceted diabetes care intervention...
  30. pmc Cardiovascular autonomic neuropathy, HDL cholesterol, and smoking correlate with arterial stiffness markers determined 18 years later in type 1 diabetes
    Catherine T Prince
    Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
    Diabetes Care 33:652-7. 2010
    ..This association persists after adjustment for potential confounders as well as for baseline HbA(1), HDL cholesterol, and smoking history, which were also associated with these PWA measures...
  31. ncbi request reprint Incidence of ESRD and survival after renal replacement therapy in patients with type 1 diabetes: a report from the Allegheny County Registry
    Rimei Nishimura
    Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA, USA
    Am J Kidney Dis 42:117-24. 2003
    ..Little information is available regarding the long-term incidence of end-stage renal disease (ESRD) and survival after the introduction of renal replacement therapy (RRT) in patients with type 1 diabetes...
  32. pmc Free fatty acids are associated with pulse pressure in women, but not men, with type 1 diabetes mellitus
    Baqiyyah Conway
    Department of Epidemiology, The University of Pittsburgh, Pittsburgh, PA 15213, USA
    Metabolism 58:1215-21. 2009
    ..This finding might help explain the loss of the sex difference in CVD in T1D...
  33. pmc Cost-effectiveness analysis of efforts to reduce risk of type 2 diabetes and cardiovascular disease in southwestern Pennsylvania, 2005-2007
    Kenneth J Smith
    University of Pittsburgh, Pittsburgh, Pennsylvania 15213, USA
    Prev Chronic Dis 7:A109. 2010
    ..We assessed the cost-effectiveness of a community-based, modified Diabetes Prevention Program (DPP) designed to reduce risk factors for type 2 diabetes and cardiovascular disease...
  34. doi request reprint A novel approach to diabetes prevention: evaluation of the Group Lifestyle Balance program delivered via DVD
    M Kaye Kramer
    University of Pittsburgh, Graduate School of Public Health, Pittsburgh, PA 15213, USA
    Diabetes Res Clin Pract 90:e60-3. 2010
    ..Results suggest that GLB-DVD with remote support may provide an effective alternative for GLB delivery...
  35. ncbi request reprint Antioxidants and coronary artery disease among individuals with type 1 diabetes: Findings from the Pittsburgh Epidemiology of Diabetes Complications Study
    Tina Costacou
    Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA 15213, USA
    J Diabetes Complications 20:387-94. 2006
    ..Oxidative stress has been implicated in the development of diabetes and cardiovascular disease. We evaluated the effect of serum antioxidants and total antioxidant reserve (TAR) on coronary artery disease (CAD) incidence in type 1 diabetes...
  36. ncbi request reprint The socioeconomic correlates of global complication prevalence in type 1 diabetes (T1D): a multinational comparison
    Michael G Walsh
    Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, DLR Building, 3512 Fifth Avenue, 2nd Floor, Pittsburgh, PA 15213, USA
    Diabetes Res Clin Pract 70:143-50. 2005
    ..In conclusion, health system performance, social distribution of wealth and purchasing power may play important roles in explaining the geographic variation of diabetes complications...
  37. pmc Predictors of and survival after incident stroke in type 1 diabetes
    Aaron M Secrest
    Department of Epidemiology, University of Pittsburgh, Pittsburgh, PA 15260, USA
    Diab Vasc Dis Res 10:3-10. 2013
    ..03). These risk factors merit careful evaluation and management to prevent stroke in T1DM, which occurs at least 20 years earlier than in the general population...
  38. ncbi request reprint Developing and validating a diabetes database in a large health system
    Janice C Zgibor
    University of Pittsburgh, Department of Epidemiology, Graduate School of Public Health, Pittsburgh, United States
    Diabetes Res Clin Pract 75:313-9. 2007
    ..Most registries are built based on membership with an insurer or other selection criteria. Little, if any data exist on registries representing demographically heterogeneous populations...
  39. ncbi request reprint Lower-extremity arterial calcification as a correlate of coronary artery calcification
    Tina Costacou
    Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA, USA
    Metabolism 55:1689-96. 2006
    ..Thus, factors related to the calcification process in addition to vascular risk factors may play a role in determining the extent of CAC...
  40. ncbi request reprint Cardiovascular disease risk prediction in type 1 diabetes: accounting for the differences
    Kristine Ruppert
    Department of Epidemiology, University of Pittsburgh Graduate School of Public Health, Pittsburgh, PA, United States
    Diabetes Res Clin Pract 78:234-7. 2007
    ..005), non-HDLc (p=0.0005), WHR (p=0.003), and estimated glucose disposal rate (p=0.002) were associated. Risk factors not considered by the Framingham risk equation may account for the lack of fit and should be examined further...
  41. pmc Retinal vessel diameter and the incidence of coronary artery disease in type 1 diabetes
    Rachel G Miller
    University of Pittsburgh, Department of Epidemiology, Graduate School of Public Health, Pittsburgh, Pennsylvania 15213, USA
    Am J Ophthalmol 147:653-60. 2009
    ..To examine the relationship between retinal vessel diameter and coronary artery disease (CAD) incidence in type 1 diabetes (T1D) using data from the Pittsburgh Epidemiology of Diabetes Complications (EDC) Study...
  42. pmc Development of a coronary heart disease risk prediction model for type 1 diabetes: the Pittsburgh CHD in Type 1 Diabetes Risk Model
    Janice C Zgibor
    University of Pittsburgh, Department of Epidemiology, Graduate School of Public Health, USA
    Diabetes Res Clin Pract 88:314-21. 2010
    ..To create a coronary heart disease (CHD) risk prediction model specific to type 1 diabetes...
  43. pmc Association of socioeconomic status with mortality in type 1 diabetes: the Pittsburgh epidemiology of diabetes complications study
    Aaron M Secrest
    Department of Epidemiology, University of Pittsburgh, Pittsburgh, PA 15213, USA
    Ann Epidemiol 21:367-73. 2011
    ..Socioeconomic status (SES) as a risk factor for mortality in type 1 diabetes (T1D) has not been adequately studied prospectively...
  44. ncbi request reprint Postpartum adiponectin concentration, insulin resistance and metabolic abnormalities among women with pregnancy-induced disturbances
    Tina Costacou
    University of Pittsburgh, Department of Epidemiology, Pittsburgh, PA 15213, USA
    Prev Cardiol 11:106-15. 2008
    ..5 microg/mL provided the optimal cutoff to distinguish those with or without MS. Thus, a lower postpartum adiponectin concentration identifies women at increased cardiovascular risk regardless of pregnancy history...
  45. ncbi request reprint Adiponectin: good, bad, or just plain ugly?
    Tina Costacou
    Department of Epidemiology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
    Kidney Int 74:549-51. 2008
    ..However, studies in humans have reported inverse as well as positive associations between adiponectin concentrations and disease states. This Commentary discusses the apparent conflict in the literature...
  46. ncbi request reprint Has control of hypercholesterolemia and hypertension in type 1 diabetes improved over time?
    Janice C Zgibor
    Department of Epidemiology, University of Pittsburgh, PA, USA
    Diabetes Care 28:521-6. 2005
    ..To determine the extent to which patients' awareness, treatment, and control of hypertension and hypercholesterolemia have changed over time and to examine factors associated with awareness and treatment in a type 1 diabetes population...
  47. ncbi request reprint Changes in glycaemic control and risk of coronary artery disease in type 1 diabetes mellitus: findings from the Pittsburgh Epidemiology of Diabetes Complications Study (EDC)
    C T Prince
    Department of Epidemiology, University of Pittsburgh Graduate School of Public Health, 3512 Fifth Avenue, Second Floor, Pittsburgh, PA 15213, USA
    Diabetologia 50:2280-8. 2007
    ....
  48. ncbi request reprint All-cause mortality in a population-based type 1 diabetes cohort in the U.S. Virgin Islands
    Raynard E Washington
    Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA, United States Electronic address
    Diabetes Res Clin Pract 103:504-9. 2014
    ..S. Virgin Islands (USVI). As such, the objective of this study was to estimate type 1 diabetes mortality in a population-based registry sample in the USVI...
  49. doi request reprint Incidence of type 1 and type 2 diabetes in youth in the U.S. Virgin Islands, 2001-2010
    Raynard E Washington
    Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA 15213, USA
    Pediatr Diabetes 14:280-7. 2013
    ..To report the annual incidence of type 1 and type 2 diabetes among youth and to describe characteristics of youth diagnosed with diabetes in the U.S. Virgin Islands (USVI)...
  50. pmc Differential effect of glycemia on the incidence of hypertension by sex: the epidemiology of diabetes complications study
    Tina Costacou
    Department of Epidemiology, University of Pittsburgh, Pittsburgh, PA, USA
    Diabetes Care 36:77-83. 2013
    ..We thus sought to confirm these observations and, given sex differences in other type 1 diabetes complications and risk factors, assessed whether any such associations differ by sex...
  51. pmc Improvements in the life expectancy of type 1 diabetes: the Pittsburgh Epidemiology of Diabetes Complications study cohort
    Rachel G Miller
    Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA, USA
    Diabetes 61:2987-92. 2012
    ....
  52. pmc Regional adiposity and risk for coronary artery disease in type 1 diabetes: does having greater amounts of gluteal-femoral adiposity lower the risk?
    Christina M Shay
    Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA, USA
    Diabetes Res Clin Pract 89:288-95. 2010
    ..Evidence suggests that the degree of gluteal-femoral adiposity may be inversely associated with coronary artery disease (CAD) risk; however, this association has not been evaluated in type 1 diabetes (T1D)...
  53. ncbi request reprint Influence of health care providers on the development of diabetes complications: long-term follow-up from the Pittsburgh Epidemiology of Diabetes Complications Study
    Janice C Zgibor
    Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania 15213, USA
    Diabetes Care 25:1584-90. 2002
    ..To quantify total diabetes care received (generalist or specialist) from diagnosis onward and its association with the incidence of diabetes complications in a representative cohort of patients with type 1 diabetes...
  54. ncbi request reprint Deficiencies of cardiovascular risk prediction models for type 1 diabetes
    Janice C Zgibor
    Department of Epidemiology, University of Pittsburgh Graduate School of Public Health, USA
    Diabetes Care 29:1860-5. 2006
    ..Therefore, our objective was to examine the accuracy of Framingham and UKPDS models for predicting coronary heart disease (CHD) in a type 1 diabetic cohort...
  55. ncbi request reprint The prediction of major outcomes of type 1 diabetes: a 12-year prospective evaluation of three separate definitions of the metabolic syndrome and their components and estimated glucose disposal rate: the Pittsburgh Epidemiology of Diabetes Complications S
    Georgia Pambianco
    Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
    Diabetes Care 30:1248-54. 2007
    ....
  56. ncbi request reprint ACE inhibitors and calcium channel blockers: patterns of use and associations with mortality in type 1 diabetes
    Brad A Sobolewski
    University of Pittsburgh School of Medicine, 3512 5th Avenue, Pittsburgh, PA 15213, USA
    Diabetes Res Clin Pract 65:37-43. 2004
    ..To determine the frequency of ACE-I and Calcium channel blockers (CCB) use in type 1 diabetes (T1D), and associations of these medications with mortality...
  57. ncbi request reprint Lipoprotein subclass measurements by nuclear magnetic resonance spectroscopy improve the prediction of coronary artery disease in Type 1 diabetes. A prospective report from the Pittsburgh Epidemiology of Diabetes Complications Study
    S S Soedamah-Muthu
    Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA, USA
    Diabetologia 46:674-82. 2003
    ..To examine whether nuclear magnetic resonance lipoprotein spectroscopy improves the prediction of coronary artery disease in patients with Type 1 diabetes, independently of conventional lipid and other risk factors...
  58. pmc Frontal gray matter atrophy in middle aged adults with type 1 diabetes is independent of cardiovascular risk factors and diabetes complications
    Timothy M Hughes
    Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania
    J Diabetes Complications 27:558-64. 2013
    ..g. fronto-subcortical networks; and if these differences are explained by cardiovascular risk factors and diabetes complications...
  59. pmc Control of lipids at baseline in the Bypass Angioplasty Revascularization Investigation 2 Diabetes (BARI 2D) trial
    Georgia Pambianco
    Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA, USA
    Prev Cardiol 12:9-18. 2009
    ..Geographic variation was seen and was not fully accounted for by demographic or treatment characteristics (all P values < .05)...
  60. pmc High-density lipoprotein cholesterol in diabetes: is higher always better?
    Tina Costacou
    Department of Epidemiology, University of Pittsburgh, PA 15213, USA
    J Clin Lipidol 5:387-94. 2011
    ..To what degree this is true in type 1 diabetes is unknown, although cardiovascular risk is increased despite elevated mean HDL-C...
  61. doi request reprint When are type 1 diabetic patients at risk for cardiovascular disease?
    Trevor J Orchard
    Department of Epidemiology, University of Pittsburgh, 3512 Fifth Avenue, Pittsburgh, PA 15213, USA
    Curr Diab Rep 10:48-54. 2010
    ..This article also briefly discusses recent data on general cardiovascular risk factors and provides updated comments concerning the association of coronary artery disease with other diabetes complications, especially renal disease...
  62. ncbi request reprint Middle-aged premenopausal women with type 1 diabetes have lower bone mineral density and calcaneal quantitative ultrasound than nondiabetic women
    Elsa S Strotmeyer
    Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, 130 North Bellefield Ave, Room 519, Pittsburgh, PA 15213, USA
    Diabetes Care 29:306-11. 2006
    ..To determine whether middle-aged premenopausal women with type 1 diabetes had more self-reported fractures and lower bone mineral density (BMD) compared with nondiabetic women...
  63. ncbi request reprint Translating the chronic care model into the community: results from a randomized controlled trial of a multifaceted diabetes care intervention
    Gretchen A Piatt
    Department of Epidemiology, University of Pittsburgh, PA 15213, USA
    Diabetes Care 29:811-7. 2006
    ..To determine whether using the chronic care model (CCM) in an underserved community leads to improved clinical and behavioral outcomes for people with diabetes...
  64. pmc Skin intrinsic fluorescence correlates with autonomic and distal symmetrical polyneuropathy in individuals with type 1 diabetes
    Baqiyyah N Conway
    Division of Epidemiology, Vanderbilt University, Nashville, Tennessee, USA
    Diabetes Care 34:1000-5. 2011
    ....
  65. ncbi request reprint Effect of lipid reduction on the progression of renal disease: a meta-analysis
    L F Fried
    Renal Electrolyte Division, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15213, USA
    Kidney Int 59:260-9. 2001
    ..We examined the effects of antilipemic agents on glomerular filtration rate and proteinuria or albuminuria in patients with renal disease...
  66. ncbi request reprint The association between a family history of type 2 diabetes and coronary artery disease in a type 1 diabetes population
    J R Erbey
    Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pennsylvania, USA
    Diabetes Care 21:610-4. 1998
    ..Because the etiologies of type 1 and type 2 diabetes are different, it is possible that some CAD in type 1 diabetes may be related to the coexistence of type 2 diabetes susceptibility (i.e., insulin resistance)...
  67. ncbi request reprint The association of diabetes specialist care with health care practices and glycemic control in patients with type 1 diabetes: a cross-sectional analysis from the Pittsburgh epidemiology of diabetes complications study
    J C Zgibor
    Department of Medicine, University of Pittsburgh, Pennsylvania, USA
    Diabetes Care 23:472-6. 2000
    ..To determine whether diabetes care characteristics and glycemic control differ by use of specialist care in a representative cohort of patients with type 1 diabetes...
  68. ncbi request reprint Lipid modulation in insulin-dependent diabetes mellitus: effect on microvascular outcomes
    L F Fried
    Renal Electrolyte Division, University of Pittsburgh School of Medicine, 938 Scaife Hall, 3550 Terrace Street, Pittsburgh, PA 15213, USA
    J Diabetes Complications 15:113-9. 2001
    ..In conclusion, treatment with simvastatin may have a beneficial effect on early nephropathy and diabetic neuropathy, justifying a fully powered trial. However, this would be difficult under current treatment guidelines...
  69. ncbi request reprint Hypotheses, design, and methods for the Bypass Angioplasty Revascularization Investigation 2 Diabetes (BARI 2D) Trial
    Maria Mori Brooks
    Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania 15261, USA
    Am J Cardiol 97:9G-19G. 2006
    ....
  70. ncbi request reprint Polycystic ovarian syndrome (PCOS): a significant contributor to the overall burden of type 2 diabetes in women
    Evelyn O Talbott
    Department of Epidemiology, University of Pittsburgh Graduate School of Public Health, Pittsburgh, Pennsylvania 15261, USA
    J Womens Health (Larchmt) 16:191-7. 2007
    ..g., PCOS) to the burden of type 2 diabetes in the total population of middle-aged women...
  71. ncbi request reprint IDDM incidence in a multiracial population. The Hawaii IDDM Registry, 1980-1990
    S L Patrick
    World Health Organization Collaborating Center for Diabetes Research, Registries and Training, Department of Epidemiology, University of Pittsburgh Graduate School of Public Health, Pittsburgh, Pennsylvania, USA
    Diabetes Care 20:983-7. 1997
    ..Because of the multiracial population living in Hawaii, it is an ideal state in which to study the effect of migration on IDDM incidence...
  72. ncbi request reprint The prospective association between adiponectin and coronary artery disease among individuals with type 1 diabetes. The Pittsburgh Epidemiology of Diabetes Complications Study
    T Costacou
    Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA, USA
    Diabetologia 48:41-8. 2005
    ..We assessed the prospective association between adiponectin concentration and coronary artery disease in individuals with type 1 diabetes...
  73. ncbi request reprint The relationship between physical activity and lipoprotein subclasses in postmenopausal women: the influence of hormone therapy
    Kelley K Pettee
    Department of Epidemiology, Internal Medicine, Department of Medicine, University of Pittsburgh, Pittsburgh, PA, USA
    Menopause 14:115-22. 2007
    ..This study's objective was to determine if the association between physical activity and lipids and lipoprotein subclasses in postmenopausal women varies by hormone therapy (HT) use...
  74. ncbi request reprint Subclinical atherosclerosis and estimated glucose disposal rate as predictors of mortality in type 1 diabetes
    Jon C Olson
    Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA, USA
    Ann Epidemiol 12:331-7. 2002
    ....
  75. ncbi request reprint Cognitive efficiency declines over time in adults with Type 1 diabetes: effects of micro- and macrovascular complications
    C M Ryan
    Western Psychiatric Institute and Clinic, University of Pittsburgh School of Medicine, 3811 O Hara Street, Pittsburgh, PA 15213, USA
    Diabetologia 46:940-8. 2003
    ....
  76. ncbi request reprint Waist to hip ratio and psychosocial factors in adults with insulin-dependent diabetes mellitus: the Pittsburgh Epidemiology of Diabetes Complications study
    C E Lloyd
    Department of Epidemiology, University of Pittsburgh, PA, USA
    Metabolism 45:268-72. 1996
    ....
  77. ncbi request reprint Mortality trends in type 1 diabetes. The Allegheny County (Pennsylvania) Registry 1965-1999
    R Nishimura
    Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pennsylvania, USA
    Diabetes Care 24:823-7. 2001
    ..This improvement is consistent with the introduction of HbA1 testing, home blood glucose monitoring, and improved blood pressure therapy in the 1980s...
  78. ncbi request reprint Excess mortality in Black compared with White patients with Type 1 diabetes: an examination of underlying causes
    Z Bosnyak
    Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, and Department of Pediatrics, Children s Hospital of Pittsburgh, PA 15213, USA
    Diabet Med 22:1636-41. 2005
    ..Excess mortality in Type 1 diabetes has previously been found among Black individuals. The aim of the present study was therefore to determine underlying causes...
  79. ncbi request reprint A multinational comparison of complications assessment in type 1 diabetes: the DiaMond substudy of complications (DiaComp) level 2
    Michael G Walsh
    Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
    Diabetes Care 27:1610-7. 2004
    ....
  80. ncbi request reprint Improving adherence to a cholesterol-lowering diet: a behavioral intervention study
    Lora E Burke
    University of Pittsburgh School of Nursing, 415 Victoria Building, Pittsburgh, PA 15261, USA
    Patient Educ Couns 57:134-42. 2005
    ..The study's findings confirm that the telephone is a useful tool to deliver adherence-enhancing interventions...
  81. ncbi request reprint Glycemia (or, in women, estimated glucose disposal rate) predict lower extremity arterial disease events in type 1 diabetes
    Jon C Olson
    Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA, USA
    Metabolism 51:248-54. 2002
    ..In women, the model with eGDR showed a significantly better fit. Glycemia, insulin resistance, hypertension and renal disease are powerful predictors of symptomatic lower extremity arterial disease in type 1 diabetes...
  82. pmc Adiposity and mortality in type 1 diabetes
    B Conway
    Department of Epidemiology, The University of Pittsburgh, Pittsburgh, PA 15217, USA
    Int J Obes (Lond) 33:796-805. 2009
    ..As intensified insulin therapy (IIT) may promote weight gain, the impact of weight gain in T1D is of importance. We therefore assessed the association of adiposity with mortality in 655 EDC participants during 20 years of follow-up...
  83. ncbi request reprint Do plasminogen activator inhibitor (PAI-1) or tissue plasminogen activator PAI-1 complexes predict complications in Type 1 diabetes: the Pittsburgh Epidemiology of Diabetes Complications Study
    Z Bosnyak
    Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, PA 15213, USA
    Diabet Med 20:147-51. 2003
    ....
  84. ncbi request reprint Clinical factors associated with resistance to microvascular complications in diabetic patients of extreme disease duration: the 50-year medalist study
    Hillary A Keenan
    Joslin Diabetes Center, One Joslin Place, Boston, MA 02215, USA
    Diabetes Care 30:1995-7. 2007
  85. ncbi request reprint Prevention Conference VI: Diabetes and Cardiovascular Disease: Writing Group III: risk assessment in persons with diabetes
    Rita F Redberg
    Circulation 105:e144-52. 2002
  86. ncbi request reprint Cross-cultural comparisons of anxiety and depression in adults with type 1 diabetes
    Cathy E Lloyd
    Birmingham Heartlands Hospital and University of Birmingham, Birmingham, UK
    Diabetes Metab Res Rev 19:401-7. 2003
    ..The aim of this study was to examine cross-cultural differences in prevalence and correlates of symptoms of anxiety and depression in two studies, one in the United Kingdom and one in the United States...
  87. pmc The effect of intensive glycemic treatment on coronary artery calcification in type 1 diabetic participants of the Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications (DCCT/EDIC) Study
    Patricia A Cleary
    Diabetes Unit, Massachusetts General Hospital, 32 Fruit St, Boston, MA 02114 2698, USA
    Diabetes 55:3556-65. 2006
    ..Prior intensive diabetes treatment during the DCCT was associated with less atherosclerosis, largely because of reduced levels of A1C during the DCCT...
  88. pmc Modifications of coronary risk factors
    Jeanine Albu
    The New York Obesity Research Center, St Luke s Roosevelt Hospital Center, University Hospital of Columbia University, College of Physicians and Surgeons, Columbia University, New York, New York 10025, USA
    Am J Cardiol 97:41G-52G. 2006
    ....
  89. pmc Discontinuing hormone replacement therapy: attenuating the effect on CVD risk with lifestyle changes
    Kelley K Pettee
    Department of Exercise and Wellness, Arizona State University, 7350 E Unity Drive, Mesa, AZ 85212, USA
    Am J Prev Med 32:483-9. 2007
    ..Concern about the potential risks associated with hormone replacement therapy (HRT) has left post-menopausal women and healthcare providers searching for safe and effective means for cardiovascular disease (CVD) risk factor reduction...
  90. pmc Multiple superoxide dismutase 1/splicing factor serine alanine 15 variants are associated with the development and progression of diabetic nephropathy: the Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications G
    Hussam Al-Kateb
    Program in Genetics and Genome Biology, The Hospital for Sick Children, TMDT Building East Tower, Rm 15 707, 101 College St, Toronto, Ontario, Canada
    Diabetes 57:218-28. 2008
    ..Despite familial clustering of nephropathy and retinopathy severity in type 1 diabetes, few gene variants have been consistently associated with these outcomes...
  91. ncbi request reprint The effect of rosiglitazone on overweight subjects with type 1 diabetes
    Trevor J Orchard
    Diabetes Care 29:746-7; author reply 747. 2006
  92. ncbi request reprint A multinational assessment of complications in type 1 diabetes: the DiaMond substudy of complications (DiaComp) level 1
    Michael G Walsh
    Division of Epidemiology, Department of Environmental Medicine, New York University Medical Center School of Medicine, 530 First Avenue, New York, NY 10016, USA
    Diab Vasc Dis Res 3:84-92. 2006
    ..However, the healthcare practice variables that were measured contributed little toward explaining this variation...
  93. pmc Intensive diabetes treatment and cardiovascular disease in patients with type 1 diabetes
    David M Nathan
    N Engl J Med 353:2643-53. 2005
    ..We studied whether the use of intensive therapy as compared with conventional therapy during the Diabetes Control and Complications Trial (DCCT) affected the long-term incidence of cardiovascular disease...
  94. pmc The effect of metformin and intensive lifestyle intervention on the metabolic syndrome: the Diabetes Prevention Program randomized trial
    Trevor J Orchard
    Diabetes Prevention Program Coordinating Center, The Biostatistics Center, George Washington University, Rockville, Maryland 20852, USA
    Ann Intern Med 142:611-9. 2005
    ..The metabolic syndrome is a high-risk state for diabetes and cardiovascular disease. Little is known about its prevalence and prevention in those with impaired glucose tolerance...
  95. ncbi request reprint Depressive symptomatology and coronary heart disease in Type I diabetes mellitus: a study of possible mechanisms
    Leslie S Kinder
    Stanford Center for Research in Disease Prevention, School of Medicine, Stanford University, USA
    Health Psychol 21:542-52. 2002
    ..Future research should clarify causal pathways between depressive symptomatology, behavioral and physiological processes, and CHD...
  96. ncbi request reprint Ischemic ECG changes predict coronary artery disease in type 1 diabetes
    Jon C Olson
    Int J Cardiol 98:511. 2005
  97. ncbi request reprint The relationship of fasting serum radioimmune insulin levels to incident coronary heart disease in an insulin-treated diabetic cohort
    Richard A Kronmal
    Department of Biostatistics, University of Washington, Seattle, Washington 98115, USA
    J Clin Endocrinol Metab 89:2852-8. 2004
    ..These observational findings should be confirmed through larger prospective studies, given their implications for insulin therapy...
  98. ncbi request reprint Late diabetes complications and non-dipping phenomenon in patients with Type 1 diabetes
    Peter Stella
    4th Department of Medicine, St Imre Hospital, Budapest, Hungary
    Diabetes Res Clin Pract 71:14-20. 2006
    ..Previous analyses also suggest however that nephropathy is a major predictor of subsequent CAN...
  99. pmc Performance of whole-genome amplified DNA isolated from serum and plasma on high-density single nucleotide polymorphism arrays
    Daniel T Croft
    Clinical Breast Care Project, Windber Research Institute, Windber, PA, USA
    J Mol Diagn 10:249-57. 2008
    ....
  100. ncbi request reprint Survival after pancreas transplantation in patients with diabetes and preserved kidney function
    Jeffrey M Venstrom
    Transplantation and Autoimmunity Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20892, USA
    JAMA 290:2817-23. 2003
    ..Whether transplantation offers a survival advantage over conventional therapies for diabetes is unknown...

Research Grants37

  1. EPIDEMIOLOGY OF DIABETIC COMPLICATIONS--PHASE II
    Trevor Orchard; Fiscal Year: 2001
    ..The investigators state that this study will continue to advance our knowledge of the pathogenesis and prediction of complications of diabetes and lead to appropriate preventive strategies. ..
  2. EPIDEMIOLOGY OF DIABETIC COMPLICATIONS--PHASE II
    Trevor Orchard; Fiscal Year: 2002
    ..The investigators state that this study will continue to advance our knowledge of the pathogenesis and prediction of complications of diabetes and lead to appropriate preventive strategies. ..
  3. EPIDEMIOLOGY OF DIABETIC COMPLICATIONS--PHASE II
    Trevor Orchard; Fiscal Year: 2002
    ..The investigators state that this study will continue to advance our knowledge of the pathogenesis and prediction of complications of diabetes and lead to appropriate preventive strategies. ..
  4. EPIDEMIOLOGY OF DIABETIC COMPLICATIONS--PHASE II
    Trevor Orchard; Fiscal Year: 2003
    ..The investigators state that this study will continue to advance our knowledge of the pathogenesis and prediction of complications of diabetes and lead to appropriate preventive strategies. ..
  5. EPIDEMIOLOGY OF DIABETIC COMPLICATIONS--PHASE II
    Trevor Orchard; Fiscal Year: 2003
    ..The investigators state that this study will continue to advance our knowledge of the pathogenesis and prediction of complications of diabetes and lead to appropriate preventive strategies. ..
  6. Epidemiology of Diabetes Complication:Phase II
    Trevor Orchard; Fiscal Year: 2004
    ..This study will continue to advance our knowledge of diabetes complications and lead to appropriate preventive strategies. ..
  7. Progression of Cardiovascular Disease in TID: CADRE/EDC
    Trevor Orchard; Fiscal Year: 2004
    ..This study will help advance our knowledge of CAD in T1D and hopefully lead to appropriate preventative strategies. ..
  8. Epidemiology of Diabetes Complication:Phase II
    Trevor Orchard; Fiscal Year: 2005
    ..This study will continue to advance our knowledge of diabetes complications and lead to appropriate preventive strategies. ..
  9. Progression of Cardiovascular Disease in TID: CADRE/EDC
    Trevor Orchard; Fiscal Year: 2005
    ..This study will help advance our knowledge of CAD in T1D and hopefully lead to appropriate preventative strategies. ..
  10. Epidemiology of Diabetes Complication:Phase II
    Trevor Orchard; Fiscal Year: 2006
    ..This study will continue to advance our knowledge of diabetes complications and lead to appropriate preventive strategies. ..
  11. Progression of Cardiovascular Disease in TID: CADRE/EDC
    Trevor Orchard; Fiscal Year: 2006
    ..This study will help advance our knowledge of CAD in T1D and hopefully lead to appropriate preventative strategies. ..
  12. DIABETES PREVENTION PROGRAM
    Trevor Orchard; Fiscal Year: 2007
    ..women, and in older subjects in the DPP. The current application is for 5 years of funding, although the some of the goals of the projects described will require a 10-year study. ..
  13. Epidemiology of Diabetes Complication:Phase II
    Trevor Orchard; Fiscal Year: 2007
    ..This study will continue to advance our knowledge of diabetes complications and lead to appropriate preventive strategies. ..
  14. Progression of Cardiovascular Disease in TID: CADRE/EDC
    Trevor Orchard; Fiscal Year: 2007
    ..This study will help advance our knowledge of CAD in T1D and hopefully lead to appropriate preventative strategies. ..
  15. EPIDEMIOLOGY OF DIABETIC COMPLICATIONS--PHASE II
    Trevor Orchard; Fiscal Year: 2000
    ..The investigators state that this study will continue to advance our knowledge of the pathogenesis and prediction of complications of diabetes and lead to appropriate preventive strategies. ..
  16. EPIDEMIOLOGY OF DIABETIC COMPLICATIONS
    Trevor Orchard; Fiscal Year: 1993
    ..In this way, we will identify the risk factors responsible for complications prospectively and be able to examine the interrelationships of IDDM complications. This should lead to the development of appropriate preventive strategies...
  17. EPIDEMIOLOGY OF DIABETIC COMPLICATIONS
    Trevor Orchard; Fiscal Year: 1992
    ..In this way, we will identify the risk factors responsible for complications prospectively and be able to examine the interrelationships of IDDM complications. This should lead to the development of appropriate preventive strategies...
  18. EPIDEMIOLOGY OF DIABETIC COMPLICATIONS--PHASE II
    Trevor Orchard; Fiscal Year: 1999
    ..The investigators state that this study will continue to advance our knowledge of the pathogenesis and prediction of complications of diabetes and lead to appropriate preventive strategies. ..
  19. EPIDEMIOLOGY OF DIABETIC COMPLICATIONS
    Trevor Orchard; Fiscal Year: 1990
    ..In this way, we will identify the risk factors responsible for complications prospectively and be able to examine the interrelationships of IDDM complications. This should lead to the development of appropriate preventive strategies...
  20. EPIDEMIOLOGY OF DIABETIC COMPLICATIONS
    Trevor Orchard; Fiscal Year: 1991
    ..In this way, we will identify the risk factors responsible for complications prospectively and be able to examine the interrelationships of IDDM complications. This should lead to the development of appropriate preventive strategies...
  21. Epidemiology of Diabetes Complication:Phase II
    Trevor Orchard; Fiscal Year: 2007
    ..This study will continue to advance our knowledge of diabetes complications and lead to appropriate preventive strategies. ..