T Ono

Summary

Affiliation: University of California
Country: USA

Publications

  1. ncbi request reprint Xeroderma pigmentosum variant heterozygotes show reduced levels of recovery of replicative DNA synthesis in the presence of caffeine after ultraviolet irradiation
    T Itoh
    Department of Molecular and Cell Biology, Division of Biochemistry and Molecular Biology, University of California, Berkeley, California 94720 3206, USA
    J Invest Dermatol 115:981-5. 2000
  2. ncbi request reprint Reinvestigation of the classification of five cell strains of xeroderma pigmentosum group E with reclassification of three of them
    T Itoh
    Department of Cell Genetics, Institute of Molecular Embryology and Genetics, Kumamoto University School of Medicine, Kumamoto, Japan
    J Invest Dermatol 114:1022-9. 2000
  3. ncbi request reprint A case of malignant melanoma: disease progression correlated with serum levels of 5-S-Cysteinyldopa (5-S-CD) and intercellular adhesion molecule-1 (ICAM-1)
    Z Ye
    Department of Dermatology, Kumamoto University School of Medicine, Japan
    J Dermatol 22:370-5. 1995
  4. ncbi request reprint Immunohistochemical demonstration of carcinoembryonic antigen and related antigens in various cutaneous keratinous neoplasms and verruca vulgaris
    K Egawa
    Department of Dermatology, Kumamoto University School of Medicine, 1 1 1 Honjo, Kumamoto 860, Japan
    Br J Dermatol 139:178-85. 1998
  5. ncbi request reprint Differential expression of MART-1 in primary and metastatic melanoma lesions
    T Kageshita
    Department of Dermatology, Kumamoto University School of Medicine, Japan
    J Immunother 20:460-5. 1997
  6. ncbi request reprint Pigmented viral warts: a clinical and histopathological study including human papillomavirus typing
    K Egawa
    Department of Dermatology, University School of Medicine, Kumamoto, Japan
    Br J Dermatol 138:381-9. 1998
  7. ncbi request reprint Human papillomavirus 57 identified in a plantar epidermoid cyst
    K Egawa
    Department of Dermatology, Kumamoto University School of Medicine, Japan
    Br J Dermatol 138:510-4. 1998
  8. ncbi request reprint Serum levels of sICAM-1 and 5-S-cysteinyldopa as markers of melanoma progression
    S Hirai
    Department of Dermatology, Kumamoto University School of Medicine, Japan
    Melanoma Res 7:58-62. 1997
  9. ncbi request reprint Multiple giant molluscum contagiosa with cyst formation
    K Egawa
    Department of Dermatology, Kumamoto University School of Medicine, Japan
    Am J Dermatopathol 17:414-6. 1995
  10. ncbi request reprint Molecular genetic analysis of HLA class II alleles in Japanese patients with melanoma
    T Kageshita
    Department of Dermatology, Kumamoto University School of Medicine, Japan
    Tissue Antigens 49:466-70. 1997

Collaborators

Detail Information

Publications24

  1. ncbi request reprint Xeroderma pigmentosum variant heterozygotes show reduced levels of recovery of replicative DNA synthesis in the presence of caffeine after ultraviolet irradiation
    T Itoh
    Department of Molecular and Cell Biology, Division of Biochemistry and Molecular Biology, University of California, Berkeley, California 94720 3206, USA
    J Invest Dermatol 115:981-5. 2000
    ..These results suggest that xeroderma pigmentosum variant heterozygotes can be identified by their sensitivity to ultraviolet irradiation in the presence of nontoxic levels of caffeine...
  2. ncbi request reprint Reinvestigation of the classification of five cell strains of xeroderma pigmentosum group E with reclassification of three of them
    T Itoh
    Department of Cell Genetics, Institute of Molecular Embryology and Genetics, Kumamoto University School of Medicine, Kumamoto, Japan
    J Invest Dermatol 114:1022-9. 2000
    ....
  3. ncbi request reprint A case of malignant melanoma: disease progression correlated with serum levels of 5-S-Cysteinyldopa (5-S-CD) and intercellular adhesion molecule-1 (ICAM-1)
    Z Ye
    Department of Dermatology, Kumamoto University School of Medicine, Japan
    J Dermatol 22:370-5. 1995
    ..These values may be useful markers of disease progression for malignant melanoma, because the material is easily, frequently, and non-invasively obtained at regular intervals...
  4. ncbi request reprint Immunohistochemical demonstration of carcinoembryonic antigen and related antigens in various cutaneous keratinous neoplasms and verruca vulgaris
    K Egawa
    Department of Dermatology, Kumamoto University School of Medicine, 1 1 1 Honjo, Kumamoto 860, Japan
    Br J Dermatol 139:178-85. 1998
    ....
  5. ncbi request reprint Differential expression of MART-1 in primary and metastatic melanoma lesions
    T Kageshita
    Department of Dermatology, Kumamoto University School of Medicine, Japan
    J Immunother 20:460-5. 1997
    ....
  6. ncbi request reprint Pigmented viral warts: a clinical and histopathological study including human papillomavirus typing
    K Egawa
    Department of Dermatology, University School of Medicine, Kumamoto, Japan
    Br J Dermatol 138:381-9. 1998
    ..The homogeneous intracytoplasmic inclusion bodies might also play a part in the darkening of the lesions. This is the first report dealing with the pigmentary disorder associated with specific types of HPV...
  7. ncbi request reprint Human papillomavirus 57 identified in a plantar epidermoid cyst
    K Egawa
    Department of Dermatology, Kumamoto University School of Medicine, Japan
    Br J Dermatol 138:510-4. 1998
    ..To our knowledge, this is the first case report of an epidermoid cyst, in which a different type of virus from HPV 60 was identified. Histological features of the cyst were also different those of HPV 60-associated epidermoid cysts...
  8. ncbi request reprint Serum levels of sICAM-1 and 5-S-cysteinyldopa as markers of melanoma progression
    S Hirai
    Department of Dermatology, Kumamoto University School of Medicine, Japan
    Melanoma Res 7:58-62. 1997
    ..Analysis of both sICAM-1 and 5-S-CD levels in serum will contribute greatly to monitoring the clinical course of melanoma patients...
  9. ncbi request reprint Multiple giant molluscum contagiosa with cyst formation
    K Egawa
    Department of Dermatology, Kumamoto University School of Medicine, Japan
    Am J Dermatopathol 17:414-6. 1995
    ..In one lesion, histological features suggesting a follicular origin of the cyst were seen...
  10. ncbi request reprint Molecular genetic analysis of HLA class II alleles in Japanese patients with melanoma
    T Kageshita
    Department of Dermatology, Kumamoto University School of Medicine, Japan
    Tissue Antigens 49:466-70. 1997
    ..In addition, there was no correlation between these antigens and clinical parameters. These results indicate that HLA class II alleles may not contribute to a strong susceptibility to melanoma in the Japanese...
  11. ncbi request reprint A case of viral warts with particular fibrillar intracytoplasmic inclusion bodies
    K Egawa
    Department of Dermatology, Kumamoto University School of Medicine, Kumamoto, Japan
    Dermatology 200:275-8. 2000
    ..We consider that this cytopathic effect could correspond to an HPV genotype which has not yet been characterized...
  12. ncbi request reprint Low frequency of neutralizing antibodies against natural interferon-beta during adjuvant therapy for Japanese patients with melanoma
    T Kageshita
    Department of Dermatology, Kumamoto University School of Medicine, Japan
    J Dermatol Sci 19:208-12. 1999
    ..This difference may be related to ethnic group of patients, treatment schedule, pharmacological preparation of IFN-beta and/or technical assay system used in each study...
  13. ncbi request reprint Increased serum levels of 5-S-cysteinyldopa and intercellular adhesion molecule-1 in a patient with a uterine amelanotic metastasis from a primary vaginal malignant melanoma
    Y Suenaga
    Department of Obstetrics and Gynecology, Kumamoto University School of Medicine, Kumamoto, 860 8556, Japan
    Gynecol Oncol 72:107-10. 1999
    ..The serum level of ICAM-1 was beyond the normal limit at the time of recurrence. Both the serum 5-S-CD and the ICAM-1 levels became elevated after recurrence and appeared to be correlated with disease progression...
  14. ncbi request reprint Hypercalcaemia in melanoma patients associated with increased levels of parathyroid hormone-related protein
    T Kageshita
    Department of Dermatology, Kumamoto University School of Medicine, Japan
    Melanoma Res 9:69-73. 1999
    ..Analysis of the serum PTH-rP level will contribute to the monitoring of the clinical course of patients with advanced stage melanoma...
  15. ncbi request reprint The carcinoembryonic antigen (CEA) family (CD66) expressed in melanocytic naevi is not expressed in blue naevuscell naevi in dendritic type
    K Egawa
    Department of Dermatology, Kumamoto University School of Medicine, Honjo, Japan
    J Cutan Pathol 27:351-8. 2000
    ..Although sporadic reports have regarded the expression of the carcinoembryonic antigen (CEA) family in melanoma, there has been no information about the expression in precursor lesions of melanoma such as melanocytic naevi and blue naevi...
  16. ncbi request reprint Clinical significance of MART-1 and HLA-A2 expression and CD8+ T cell infiltration in melanocytic lesions in HLA-A2 phenotype patients
    T Kageshita
    Department of Dermatology, Kumamoto University School of Medicine, 1 1 Honjo, 860 0811, Kumamoto, Japan
    J Dermatol Sci 25:36-44. 2001
    ..These findings suggest both MART-1 and HLA-A2 expression in melanoma lesions should be analyzed for selection of patients eligible for MART-1 based immunotherapy and monitoring for emergence of melanoma cells resistant to T cell therapy...
  17. ncbi request reprint Two cases of nevus comedonicus: successful treatment of keratin plugs with a pore strip
    Y Inoue
    Department of Dermatology, Kumamoto University School of Medicine, 1 1 1, Honjo, Kumamoto 860 0811, Japan
    J Am Acad Dermatol 43:927-9. 2000
    ..Nevus comedonicus is an uncommon condition of unknown cause. We used a pore strip cosmetic pack to eliminate the keratin plugs in 2 patients with nevus comedonicus, producing excellent results...
  18. ncbi request reprint Regressing Merkel cell carcinoma-a case showing replacement of tumour cells by foamy cells
    K Maruo
    Department of Dermatology, Kumamoto University School of Medicine, Kumamoto 860 0811, Japan
    Br J Dermatol 142:1184-9. 2000
    ..Histopathological analysis of the completely regressed tumour revealed that the tumour cells were completely replaced by numerous foamy cells. This is the first report demonstrating the histopathological features of regressing MCC...
  19. ncbi request reprint Nucleotide sequence of the third cytokine LD78 gene and mapping of all three LD78 gene loci to human chromosome 17
    M Hirashima
    Molecular Genetic Laboratory, Chemo Sero Therapeutic Research Institute, Kumamoto, Japan
    DNA Seq 3:203-12. 1992
    ..The mechanism of generation of the three LD78 genes is discussed...
  20. ncbi request reprint Phosphorylation of myristoylated alanine-rich C kinase substrate (MARCKS) by proline-directed protein kinases and its dephosphorylation
    H Yamamoto
    Department of Pharmacology, Kumamoto University School of Medicine, Japan
    J Neurochem 65:802-9. 1995
    ..These results suggest that cdc2 kinase and TPKII regulate the functions of MARCKS in different ways from protein kinase C...
  21. ncbi request reprint Molecular nature of ultraviolet B light-induced deletions in the murine epidermis
    M Horiguchi
    Division of Genetics and Mutagenesis, National Institute of Health Sciences, 1-18-1 Kamiyoga, Setagaya-ku, Tokyo 158-8501, Japan
    Cancer Res 61:3913-8. 2001
    ..These results suggest that UVB irradiation induces deletions in the murine epidermis, and most of the deletions are generated through end-joining of double strand breaks in DNA...
  22. ncbi request reprint Mice with only rat mtDNA are required as models of mitochondrial diseases
    M Yamaoka
    Institute of Biological Sciences, University of Tsukuba, Ibaraki, 305-8572, Japan
    Biochem Biophys Res Commun 282:707-11. 2001
    ....
  23. pmc Phosphorothioate oligonucleotides, suramin and heparin inhibit DNA-dependent protein kinase activity
    Y Hosoi
    Department of Radiation Oncology, Faculty of Medicine, University of Tokyo, Tokyo, Japan
    Br J Cancer 86:1143-9. 2002
    ..Our present observations suggest that suramin may possibly result in sensitisation of cells to ionising radiation by inactivation of DNA-dependent protein kinase and the impairment of double-stranded breaks repair...
  24. ncbi request reprint Molecular nature of mutations induced by irradiation with repeated low doses of X-rays in spleen, liver, brain and testis of lacZ-transgenic mice
    T Ono
    Department of Cell Biology, Graduate School of Medicine, Tohoku University, Seiryo machi 2 1, Aoba ku, Sendai, 980 8575 Japan
    Int J Radiat Biol 79:635-41. 2003
    ..To investigate the molecular characteristics of mutations induced by repeated low doses of X-rays in spleen, liver, brain and testis of mice...