BERT W O'MALLEY

Summary

Affiliation: University of Pennsylvania
Country: USA

Publications

  1. ncbi request reprint Transoral robotic surgery (TORS) for base of tongue neoplasms
    BERT W O'MALLEY
    Department of Otorhinolaryngology Head and Neck Surgery, University of Pennsylvania, 3400 Spruce Street, Philadelphia, PA 19104, USA
    Laryngoscope 116:1465-72. 2006
  2. doi request reprint Transoral robotic surgery for parapharyngeal space tumors
    BERT W O'MALLEY
    Department of Otorhinolaryngology, Head and Neck Surgery, University of Pennsylvania, Philadelphia, PA 19104, USA
    ORL J Otorhinolaryngol Relat Spec 72:332-6. 2010
  3. ncbi request reprint Robotic skull base surgery: preclinical investigations to human clinical application
    BERT W O'MALLEY
    Department of Otorhinolaryngology, Head and Neck Surgery, University of Pennsylvania Health System, Philadelphia, PA 19104, USA
    Arch Otolaryngol Head Neck Surg 133:1215-9. 2007
  4. ncbi request reprint Transoral robotic surgery (TORS): glottic microsurgery in a canine model
    BERT W O'MALLEY
    Department of Otorhinolaryngology Head and Neck Surgery, The University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
    J Voice 20:263-8. 2006
  5. ncbi request reprint Robotic anterior and midline skull base surgery: preclinical investigations
    BERT W O'MALLEY
    Department of Otorhinolaryngology Head and Neck Surgery, University of Pennsylvania, Philadelphia, PA 19104, USA
    Int J Radiat Oncol Biol Phys 69:S125-8. 2007
  6. pmc Molecular disruption of RAD50 sensitizes human tumor cells to cisplatin-based chemotherapy
    Waleed M Abuzeid
    Department of Otorhinolaryngology Head and Neck Surgery, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA
    J Clin Invest 119:1974-85. 2009
  7. doi request reprint Cytotoxicity and antiangiogenesis by fibroblast growth factor 2-targeted Ad-TK cancer gene therapy
    Koichiro Saito
    Department of Otorhinolaryngology Head and Neck Surgery, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA
    Laryngoscope 119:665-74. 2009
  8. doi request reprint Transoral robotic surgery: a multicenter study to assess feasibility, safety, and surgical margins
    Gregory S Weinstein
    Department of Otorhinolaryngology Head and Neck Surgery, University of Pennsylvania, Philadelphia, Pennsylvania, USA
    Laryngoscope 122:1701-7. 2012
  9. doi request reprint Chitosan glycerophosphate-based semirigid dexamethasone eluting biodegradable stent
    Benjamin S Bleier
    Department of Otorhinolaryngology Head and Neck Surgery, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania, USA
    Am J Rhinol Allergy 23:76-9. 2009
  10. ncbi request reprint Head and neck squamous cell carcinoma targeted chemosensitization
    Mindy R Figures
    Department of Otorhinolaryngology Head and Neck Surgery, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
    Otolaryngol Head Neck Surg 141:177-83. 2009

Collaborators

Detail Information

Publications77

  1. ncbi request reprint Transoral robotic surgery (TORS) for base of tongue neoplasms
    BERT W O'MALLEY
    Department of Otorhinolaryngology Head and Neck Surgery, University of Pennsylvania, 3400 Spruce Street, Philadelphia, PA 19104, USA
    Laryngoscope 116:1465-72. 2006
    ..To develop a minimally invasive surgical technique for the treatment of base of tongue neoplasms using the optical and technical advantages of robotic surgical instrumentation...
  2. doi request reprint Transoral robotic surgery for parapharyngeal space tumors
    BERT W O'MALLEY
    Department of Otorhinolaryngology, Head and Neck Surgery, University of Pennsylvania, Philadelphia, PA 19104, USA
    ORL J Otorhinolaryngol Relat Spec 72:332-6. 2010
    ..To evaluate the outcomes of patients with parapharyngeal space (PPS) tumors treated with a transoral robotic surgery (TORS) approach...
  3. ncbi request reprint Robotic skull base surgery: preclinical investigations to human clinical application
    BERT W O'MALLEY
    Department of Otorhinolaryngology, Head and Neck Surgery, University of Pennsylvania Health System, Philadelphia, PA 19104, USA
    Arch Otolaryngol Head Neck Surg 133:1215-9. 2007
    ..To develop a minimally invasive surgical technique for the treatment of parapharyngeal space and infratemporal fossa skull base neoplasms using the technical and optical advantages of robotic surgical instrumentation...
  4. ncbi request reprint Transoral robotic surgery (TORS): glottic microsurgery in a canine model
    BERT W O'MALLEY
    Department of Otorhinolaryngology Head and Neck Surgery, The University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
    J Voice 20:263-8. 2006
    ..We hypothesize that bimanual, three-dimensional robotic surgery will prove valuable for glottic microsurgical procedures...
  5. ncbi request reprint Robotic anterior and midline skull base surgery: preclinical investigations
    BERT W O'MALLEY
    Department of Otorhinolaryngology Head and Neck Surgery, University of Pennsylvania, Philadelphia, PA 19104, USA
    Int J Radiat Oncol Biol Phys 69:S125-8. 2007
    ..To develop a minimally invasive surgical technique to access the midline and anterior skull base using the optical and technical advantages of robotic surgical instrumentation...
  6. pmc Molecular disruption of RAD50 sensitizes human tumor cells to cisplatin-based chemotherapy
    Waleed M Abuzeid
    Department of Otorhinolaryngology Head and Neck Surgery, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA
    J Clin Invest 119:1974-85. 2009
    ..This strategy is potentially applicable to several types of malignant tumors that demonstrate chemoresistance and may positively impact the treatment of these patients...
  7. doi request reprint Cytotoxicity and antiangiogenesis by fibroblast growth factor 2-targeted Ad-TK cancer gene therapy
    Koichiro Saito
    Department of Otorhinolaryngology Head and Neck Surgery, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA
    Laryngoscope 119:665-74. 2009
    ....
  8. doi request reprint Transoral robotic surgery: a multicenter study to assess feasibility, safety, and surgical margins
    Gregory S Weinstein
    Department of Otorhinolaryngology Head and Neck Surgery, University of Pennsylvania, Philadelphia, Pennsylvania, USA
    Laryngoscope 122:1701-7. 2012
    ....
  9. doi request reprint Chitosan glycerophosphate-based semirigid dexamethasone eluting biodegradable stent
    Benjamin S Bleier
    Department of Otorhinolaryngology Head and Neck Surgery, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania, USA
    Am J Rhinol Allergy 23:76-9. 2009
    ..The purpose of this study was to optimize the chitosan formulation to produce a pliable sheet, to assess the innate longevity and inflammatory potential of the polymer, and to study the in vivo rate of dexamethasone release over time...
  10. ncbi request reprint Head and neck squamous cell carcinoma targeted chemosensitization
    Mindy R Figures
    Department of Otorhinolaryngology Head and Neck Surgery, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
    Otolaryngol Head Neck Surg 141:177-83. 2009
    ....
  11. doi request reprint Transoral robotic surgery of the skull base: a cadaver and feasibility study
    John Y K Lee
    Department of Neurosurgery, University of Pennsylvania, Philadelphia, PA 19104, USA
    ORL J Otorhinolaryngol Relat Spec 72:181-7. 2010
    ..The goal of this study was to determine the potential role as well as the current limitations of the da Vinci Surgical System robot in transoral surgery of the skull base...
  12. doi request reprint Selective neck dissection and deintensified postoperative radiation and chemotherapy for oropharyngeal cancer: a subset analysis of the University of Pennsylvania transoral robotic surgery trial
    Gregory S Weinstein
    Department of Otorhinolaryngology, Head and Neck Surgery, University of Pennsylvania Health System, Philadelphia, Pennsylvania 19104, USA
    Laryngoscope 120:1749-55. 2010
    ....
  13. doi request reprint Enhanced local dendritic cell activity and tumor-specific immunoresponse in combined radiofrequency ablation and interleukin-2 for the treatment of human head and neck cancer in a murine orthotopic model
    Koichiro Saito
    Department of Otorhinolaryngology Head and Neck Surgery, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA
    Head Neck 33:359-67. 2011
    ..However, induced immune response is weak and requires additional immunotherapy for optimized RFA treatment against cancer...
  14. ncbi request reprint Da Vinci Robot-assisted transoral odontoidectomy for basilar invagination
    John Y K Lee
    Department of Neurosurgery, University of Pennsylvania, Philadelphia, PA 19104, USA
    ORL J Otorhinolaryngol Relat Spec 72:91-5. 2010
    ..These problems, and the corollary aversion to the procedure felt by many neurosurgeons, led our group to investigate an alternative approach...
  15. ncbi request reprint Combination nonviral interleukin-2 gene immunotherapy for head and neck cancer: from bench top to bedside
    BERT W O'MALLEY
    Department of Otorhinolaryngology Head and Neck Surgery, The University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA
    Laryngoscope 115:391-404. 2005
    ....
  16. doi request reprint Transoral robotic surgery of craniocervical junction and atlantoaxial spine: a cadaveric study
    John Y K Lee
    Department of Neurosurgery, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
    J Neurosurg Spine 12:13-8. 2010
    ..The goal of this study was to determine the potential role and current limitations of the da Vinci surgical robot in transoral decompression of craniocervical junction (CCJ)...
  17. ncbi request reprint Transoral robotic surgery: radical tonsillectomy
    Gregory S Weinstein
    Department of Otorhinolaryngology, Head and Neck Surgery, University of Pennsylvania Health System, Philadelphia, PA 19104, USA
    Arch Otolaryngol Head Neck Surg 133:1220-6. 2007
    ..To describe and show the feasibility of a new surgical technique for transoral robotic surgery (TORS) radical tonsillectomy...
  18. ncbi request reprint Robot-assisted pharyngeal and laryngeal microsurgery: results of robotic cadaver dissections
    Neil G Hockstein
    Department of Otorhinolaryngology Head and Neck Surgery, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
    Laryngoscope 115:1003-8. 2005
    ..Robotic surgery has significant potential in pharyngeal and microlaryngeal surgery. We demonstrate the use of a surgical robot in pharyngeal and microlaryngeal surgery in a cadaver...
  19. ncbi request reprint Transoral robotic surgery in head and neck cancer: what radiologists need to know about the cutting edge
    Laurie A Loevner
    Departments of Radiology and Otorhinolaryngology Head and Neck Surgery, Perelman School of Medicine at Hospital of the University of Pennsylvania, 3400 Spruce St, 219 Dulles Bldg, Philadelphia, PA 19104
    Radiographics 33:1759-79. 2013
    ..Knowledge of the expected postoperative imaging appearances, so that they can be distinguished from recurrent disease and second primary tumors, is essential for all radiologists involved in the care of these patients. ..
  20. ncbi request reprint Transoral robotic surgery and adjuvant therapy for oropharyngeal carcinomas and the influence of p16 INK4a on treatment outcomes
    Harry Quon
    Department of Radiation Oncology, Philadelphia, Pennsylvania 19104, USA
    Laryngoscope 123:635-40. 2013
    ..To determine the prognostic influence of p16(INK4a) immunohistochemistry on the survival of resectable oropharyngeal carcinomas (OPSCC)...
  21. doi request reprint Transoral robotic surgery for advanced oropharyngeal carcinoma
    Gregory S Weinstein
    Department of Otorhinolaryngology Head and Neck Surgery, University of Pennsylvania Medical Center, Philadelphia, PA 19104, USA
    Arch Otolaryngol Head Neck Surg 136:1079-85. 2010
    ..To determine the oncologic and functional outcomes in patients undergoing primary transoral robotic surgery followed by adjuvant therapy as indicated with a minimum of 18-month follow-up for advanced oropharyngeal carcinoma...
  22. doi request reprint Transoral robotic surgery: does the ends justify the means?
    Gregory S Weinstein
    Department of Otorhinolaryngology Head and Neck Surgery, The University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
    Curr Opin Otolaryngol Head Neck Surg 17:126-31. 2009
    ..Transoral robotic surgery is in its infancy, but, indeed, there have been some questions raised about the role of these innovative robotic surgical techniques...
  23. ncbi request reprint Pilot study of postoperative reirradiation, chemotherapy, and amifostine after surgical salvage for recurrent head-and-neck cancer
    Mitchell Machtay
    Department of Radiation Oncology, University of Pennsylvania Medical Center, Philadelphia, PA, USA
    Int J Radiat Oncol Biol Phys 59:72-7. 2004
    ..We designed a prospective protocol to determine the feasibility, toxicity, and preliminary efficacy of a regimen of postoperative reirradiation, chemotherapy and the radioprotector amifostine after salvage head-and-neck surgery...
  24. doi request reprint Robotics and telesurgery in otolaryngology
    Jason G Newman
    Department of Otorhinolaryngology Head and Neck Surgery, The University of Pennsylvania Health System, 811 Spruce Street, Philadelphia, PA 19107, USA
    Otolaryngol Clin North Am 44:1317-31, viii. 2011
    ..They address procedures such as oropharyngeal transoral robotic surgery (TORS), laryngeal TORS, and thyroidectomy, and also note the role of robotics in teaching...
  25. doi request reprint Transoral robotic surgery and human papillomavirus status: Oncologic results
    Marc A Cohen
    Department of Otorhinolaryngology Head and Neck Surgery, University of Pennsylvania Medical Center, Philadelphia, Pennsylvania, USA
    Head Neck 33:573-80. 2011
    ..The purpose of this study was to assess HPV-related outcomes after transoral robotic surgery (TORS) with adjuvant therapy as indicated...
  26. doi request reprint Retinoblastoma RB94 enhances radiation treatment of head and neck squamous cell carcinoma
    Koji Araki
    Department of Otorhinolaryngology Head and Neck Surgery, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
    Clin Cancer Res 14:3514-9. 2008
    ..To assess whether adenovirus-mediated retinoblastoma 94 (Ad-RB94) transgene expression enhances efficacy of radiation therapy (XRT) of human head and neck squamous cell carcinoma (HNSCC)...
  27. doi request reprint Postoperative adjuvant therapy after transoral robotic resection for oropharyngeal carcinomas: rationale and current treatment approach
    Harry Quon
    Department of Radiation Oncology, University of Pennsylvania, Philadelphia, PA, USA
    ORL J Otorhinolaryngol Relat Spec 73:121-30. 2011
    ....
  28. doi request reprint The predictive and therapeutic value of thymidine phosphorylase and dihydropyrimidine dehydrogenase in capecitabine (Xeloda)-based chemotherapy for head and neck cancer
    Koichiro Saito
    Department of Otorhinolaryngology Head and Neck Surgery, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA
    Laryngoscope 119:82-8. 2009
    ....
  29. ncbi request reprint Endonasal laser tissue welding: first human experience
    Benjamin S Bleier
    Department of Otorhinolaryngology Head and Neck Surgery, Hospital of the University of Pennsylvania, Philadelphia, PA, USA
    Am J Rhinol Allergy 24:244-6. 2010
    ..The objective of this study is to assess the safety and technical feasibility of endoscopic LTW in human sinonasal mucosa...
  30. doi request reprint Transoral robotic surgery alone for oropharyngeal cancer: an analysis of local control
    Gregory S Weinstein
    Department of Otorhinolaryngology Head and Neck Surgery, University of Pennsylvania Medical Center, Philadelphia, USA
    Arch Otolaryngol Head Neck Surg 138:628-34. 2012
    ..To evaluate local control following transoral robotic surgery (TORS) with the da Vinci Surgical System (Intuitive Surgical Inc) as a single treatment modality for oropharyngeal squamous cell carcinoma (OSCC)...
  31. ncbi request reprint Transoral robotic surgery: supraglottic laryngectomy in a canine model
    Gregory S Weinstein
    Department of Otorhinolaryngology Head and Neck Surgery, The University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
    Laryngoscope 115:1315-9. 2005
    ..To develop a technique for computer enhanced robotic transoral supraglottic partial laryngectomy in the canine model...
  32. doi request reprint A novel orthotopic mouse model of head and neck cancer with molecular imaging
    Nishant P Reddy
    Department of Otorhinolaryngology Head and Neck Surgery, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
    Laryngoscope 121:1202-7. 2011
    ..We developed a novel orthotopic mouse model of HNC with a stable cell line expressing a red fluorescent protein gene to compare a molecular imaging tumor quantification with traditional caliper measurement...
  33. ncbi request reprint Assessment of intraoperative safety in transoral robotic surgery
    Neil G Hockstein
    Department of Otorhinolaryngology Head and Neck Surgery, University of Pennsylvania, Philadelphia, Pennsylvania, USA
    Laryngoscope 116:165-8. 2006
    ..We hypothesize that these particular risks of transoral surgery are similar with robotic assistance compared with conventional transoral surgery...
  34. doi request reprint A regulated delivery system for inner ear drug application
    Shayanne A Lajud
    Department of Otorhinolaryngology Head and Neck Surgery, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, United States
    J Control Release 166:268-76. 2013
    ..To evaluate this effect, we tested gentamicin (GENT) in the inner ear following CGP delivery with/without regulation...
  35. doi request reprint Hypoglossal nerve palsy missed and misinterpreted: the hidden skull base
    Kim O Learned
    Division of Neuroradiology, Department of Radiology, University of Pennsylvania School of Medicine, Philadelphia, PA, USA
    J Comput Assist Tomogr 36:718-24. 2012
    ..Understanding radiological patterns of tongue denervation is important to prevent misinterpretation. Close evaluation of the skull base is critical as hypoglossal palsies resulting from pathology here are often overlooked...
  36. ncbi request reprint Transoral robot-assisted lingual tonsillectomy and uvulopalatopharyngoplasty for obstructive sleep apnea
    Jonathan M Lee
    Department of Otorhinolaryngology Head and Neck Surgery, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
    Ann Otol Rhinol Laryngol 121:635-9. 2012
    ..We assessed the use of transoral robot-assisted lingual tonsillectomy and uvulopalatopharyngoplasty for the surgical management of tongue base obstruction in patients with obstructive sleep apnea...
  37. doi request reprint Molecular imaging assisted surgery improves survival in a murine head and neck cancer model
    Shunsuke Miyamoto
    Department of Otorhinolaryngology Head and Neck Surgery, University of Pennsylvania Health System, Philadelphia, PA 19104, USA
    Int J Cancer 131:1235-42. 2012
    ..The hurdles in applying this technique in clinical practice are still considerable, and further research and development is warranted...
  38. ncbi request reprint Transoral robotic surgery: supraglottic partial laryngectomy
    Gregory S Weinstein
    Department of Otorhinolaryngology Head and Neck Surgery, University of Pennsylvania, Philadelphia, Pennsylvania, USA
    Ann Otol Rhinol Laryngol 116:19-23. 2007
    ..We assessed the feasibility of performing transoral supraglottic partial laryngectomy with robotic instrumentation...
  39. ncbi request reprint Informed consent in sinus surgery: link between demographics and patient desires
    Rodney J Taylor
    Department of Otorhinolaryngology Head and Neck Surgery, University of Maryland School of Medicine, Baltimore, Maryland, USA
    Laryngoscope 115:826-31. 2005
    ..To evaluate and understand differences in expectations according to patient demographics during the informed consent process for functional endoscopic sinus surgery (FESS)...
  40. doi request reprint The chemopreventive and clinically used agent curcumin sensitizes HPV (-) but not HPV (+) HNSCC to ionizing radiation, in vitro and in a mouse orthotopic model
    STEPHEN TUTTLE
    Department of Radiation Oncology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA
    Cancer Biol Ther 13:575-84. 2012
    ..We therefore propose that curcumin and RT should be considered as a first line treatment of HPV (-) HNSCC...
  41. doi request reprint Current management of juvenile nasopharyngeal angiofibroma: a tertiary center experience 1999-2007
    Benjamin S Bleier
    Department of Otorhinolaryngology Head and Neck Surgery, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania 19104 4206, USA
    Am J Rhinol Allergy 23:328-30. 2009
    ..The purpose of this study was to report on a series of patients presenting with JNA in an effort to further define an optimal treatment algorithm and improve outcomes...
  42. doi request reprint Endoscopic resection of advanced anterior skull base lesions: oncologically safe?
    Marc A Cohen
    Department of Otorhinolaryngology, Head and Neck Surgery, University of Pennsylvania Medical Center, Philadelphia, PA 19104, USA
    ORL J Otorhinolaryngol Relat Spec 71:123-8. 2009
    ..2) Understand the difference in patient morbidity with endoscopic surgery compared to traditional CFR...
  43. ncbi request reprint Organ preservation therapy using induction plus concurrent chemoradiation for advanced resectable oropharyngeal carcinoma: a University of Pennsylvania Phase II Trial
    Mitchell Machtay
    Department of Radiation Oncology, University of Pennsylvania Medical Center, Philadelphia 19104, USA
    J Clin Oncol 20:3964-71. 2002
    ..To determine the efficacy, feasibility, and toxicity of a new regimen for locally advanced oropharyngeal carcinoma...
  44. doi request reprint A pilot study of respiratory inductance plethysmography as a safe, noninvasive detector of jet ventilation under general anesthesia
    Joshua H Atkins
    Department of Anesthesiology and Critical Care, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
    Anesth Analg 111:1168-75. 2010
    ..We performed an observational pilot study of respiratory inductance plethysmography as a detector of jet ventilation...
  45. ncbi request reprint Impact of age on clinical care pathway length of stay after complex head and neck resection
    Sarah H Kagan
    University of Pennsylvania School of Nursing, 420 Guardian Drive, Philadelphia, Pennsylvania 19104 6096, USA
    Head Neck 24:545-8; discussion 545. 2002
    ..Aggregate clinical results for 43 patients, enrolled in the CCP from June 1996-July 1997, are described. Patient age, comorbid status, and postoperative complications are analyzed with respect to impact on LOS...
  46. ncbi request reprint Clinical care pathway for head and neck cancer: a valuable tool for decreasing resource utilization
    Kristin M Gendron
    Department of Otorhinolaryngology Head and Neck Surgery, 3400 Spruce St, 5 Ravdin, Philadelphia, PA 19104, USA
    Arch Otolaryngol Head Neck Surg 128:258-62. 2002
    ..To evaluate the durability over time of the reduction of resource utilization after implementing a clinical care pathway (CCP) for head and neck cancer surgery...
  47. ncbi request reprint A phase I study of SPI-077 (Stealth liposomal cisplatin) concurrent with radiation therapy for locally advanced head and neck cancer
    David I Rosenthal
    Department of Radiation Oncology, Head and Neck Surgery, Hospital of the University of Pennsylvania, Philadelphia 19104, USA
    Invest New Drugs 20:343-9. 2002
    ..We performed a Phase I study of Stealth liposomal cisplatin (SPI-077) concurrent with RT for head and neck squamous cell carcinoma (HNSCC)...
  48. ncbi request reprint Design and impact of intraoperative pathways for head and neck resection and reconstruction
    Ara A Chalian
    Department of Otorhinolaryngology Head and Neck Surgery, Hospital of the University of Pennsylvania, Philadelphia 19104 4283, USA
    Arch Otolaryngol Head Neck Surg 128:892-6. 2002
    ....
  49. pmc Surfactants in the management of rhinopathologies
    Philip L Rosen
    Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
    Am J Rhinol Allergy 27:177-80. 2013
    ..Because of these unique physical properties several in vitro, ex vivo, and human trials have examined the role of surfactants as stand-alone or adjunct therapy in recalcitrant chronic rhinosinusitis (CRS)...
  50. doi request reprint Safety evaluation of sinus surfactant solution on respiratory cilia function
    Alexander G Chiu
    Department of Otorhinolaryngology Head and Neck Surgery, University of Pennsylvania, Philadelphia, PA, USA
    Int Forum Allergy Rhinol 1:280-3. 2011
    ..This study evaluates the safety of this solution on respiratory cilia function...
  51. doi request reprint Novel adenoviral gene delivery system targeted against head and neck cancer
    Daqing Li
    Department of Otorhinolaryngology Head and Neck Surgery, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA
    Laryngoscope 118:650-8. 2008
    ..Here, we present a novel recombinant adenovirus vector (Ad5-Flag-LDS) that demonstrated a marked targeting bias against Hsp47, a biomarker for head and neck squamous cell carcinoma (HNSCC)...
  52. doi request reprint Comparison of endoscopic and microscopic removal of pituitary adenomas: single-surgeon experience and the learning curve
    BERT W O'MALLEY
    Departments of Otorhinolaryngology, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania, USA
    Neurosurg Focus 25:E10. 2008
    ..They also attempted to determine the learning curve associated with a surgical team converting to endoscopic techniques...
  53. doi request reprint Anesthetic considerations for transoral robotic surgery
    John J Chi
    Department of Otorhinolaryngology Head and Neck Surgery, University of Pennsylvania School of Medicine, Philadelphia, 19104, USA
    Anesthesiol Clin 28:411-22. 2010
    ..This article focuses on TORS and the goal of which is to provide the anesthesiologist with a foundation for caring for the TORS patient in the perioperative period...
  54. ncbi request reprint Robotic microlaryngeal surgery: a technical feasibility study using the daVinci surgical robot and an airway mannequin
    Neil G Hockstein
    Department of Otorhinolaryngology Head and Neck Surgery, University of Pennsylvania, Philadelphia, Pennsylvania, USA
    Laryngoscope 115:780-5. 2005
    ..The purpose of this study is to demonstrate the technical feasibility of robot-assisted microlaryngeal surgery...
  55. ncbi request reprint Importance of the treatment package time in surgery and postoperative radiation therapy for squamous carcinoma of the head and neck
    David I Rosenthal
    Department of Radiation Oncology, Hospital of the University of Pennsylvania, 3400 Spruce Street, 2 Donner, Philadelphia, PA 19104, USA
    Head Neck 24:115-26. 2002
    ..Patients were also divided into intermediate- and high-risk groups on the basis of eligibility for RTOG 95-01. Univariate (logrank) and multivariate analyses were performed...
  56. ncbi request reprint Maintenance of hemostasis in transoral robotic surgery
    Neil G Hockstein
    Department of Otorhinolaryngology Head and Neck Surgery, The University of Pennsylvania, Philadelphia, PA, USA
    ORL J Otorhinolaryngol Relat Spec 67:220-4. 2005
    ..One potential limitation is the management of bleeding in transoral pharyngeal and laryngeal surgery, which is critical to prevent both intravascular volume loss and aspiration...
  57. pmc Patterns and levels of hypoxia in head and neck squamous cell carcinomas and their relationship to patient outcome
    Sydney M Evans
    Department of Radiation Oncology, School of Medicine, University of Pennsylvania, Philadelphia, PA 19104 6072, USA
    Int J Radiat Oncol Biol Phys 69:1024-31. 2007
    ..EF5, a 2-nitroimidazole hypoxia marker, was used to study the presence, levels, and prognostic significance of hypoxia in primary head and neck squamous cell tumors...
  58. pmc Surgical treatment of a clival-C2 atypical teratoid/rhabdoid tumor
    Gregory G Heuer
    Department of Neurosurgery, Children s Hospital of Philadelphia, University of Pennsylvania Medical Center, Philadelphia, Pennsylvania 19104 4399, USA
    J Neurosurg Pediatr 5:75-9. 2010
    ..The conus tumor was resected and found to be consistent with the primary tumor. Several months later the patient presented with disseminated intrathecal disease and ultimately died 42 months after the initial resection...
  59. ncbi request reprint Voice rehabilitation after external partial laryngeal surgery
    Anthony Sparano
    Department of Otorhinolaryngology Head and Neck Surgery, The University of Pennsylvania Medical Center, 3400 Spruce Street, Ravdin 5, Philadelphia, PA 19104, USA
    Otolaryngol Clin North Am 37:637-53. 2004
    ..Because the spectrum of these changes maybe broad, the role of professional rehabilitation therapy has taken an involved, multidisciplinary approach, with an integrated understanding of anticipated and potential functional outcomes...
  60. ncbi request reprint Accuracy of magnetic resonance imaging in predicting absence of fixation of head and neck cancer to the prevertebral space
    Wendy C Hsu
    Department of Radiology, University of Pennsylvania Medical Center, 3400 Spruce Street, Philadelphia, PA 19104, USA
    Head Neck 27:95-100. 2005
    ....
  61. ncbi request reprint Relative risk of stroke in head and neck carcinoma patients treated with external cervical irradiation
    Jeffrey C Haynes
    Department of Radiation Oncology, University of Pennsylvania Medical Center, Philadelphia, Pennsylvania 19104, USA
    Laryngoscope 112:1883-7. 2002
    ..To determine the rate of cerebrovascular events (stroke) in patients irradiated to high doses for squamous cell carcinoma of the head and neck...
  62. ncbi request reprint Parotidectomy in the treatment of aggressive cutaneous malignancies
    Stephen Y Lai
    Department of Otorhinolaryngology Head and Neck Surgery, University of Pennsylvania Medical Center, 5 Silverstein Ravdin, 3400 Spruce St, Philadelphia, PA 19104, USA
    Arch Otolaryngol Head Neck Surg 128:521-6. 2002
    ..Aggressive nonmelanoma skin cancer (ANMSC) of the head and neck may require parotidectomy because of neurotropic spread, direct invasion of the parotid gland, or parotid metastasis...
  63. ncbi request reprint Preliminary investigation of symptom distress in the head and neck patient population: validation of a measurement instrument
    Heather A Jones
    Department of Radiation Oncology, University of Pennsylvania School of Medicine, Philadelphia, PA, USA
    Am J Clin Oncol 29:158-62. 2006
    ..Thus, the specific aim of this pilot study was to estimate the reliability and validity of a modified version of a symptom distress scale used to assess the qualitative difference in symptom distress between the 2 populations...
  64. doi request reprint Parapharyngeal space tumors: another consideration for otalgia and temporomandibular disorders
    Courtney C Grosskopf
    Department of Oral Medicine, University of Pennsylvania School of Dental Medicine, Philadelphia, Pennsylvania, USA
    Head Neck 35:E153-6. 2013
    ..Parapharyngeal space (PPS) tumors are rare, accounting for 0.5% of all head and neck neoplasms. PPS tumors are difficult to diagnose due to limited presenting signs and symptoms and because of their location deep within the neck...
  65. doi request reprint Endoscopic closure of CSF rhinorrhea: 193 cases over 21 years
    Caroline A Banks
    Department of Otorhinolaryngology Head and Neck Surgery, University of Pennsylvania Health System, Philadelphia, PA, USA
    Otolaryngol Head Neck Surg 140:826-33. 2009
    ..Endoscopic repair of cerebrospinal fluid (CSF) leaks has become a routine approach. This study describes endoscopic closure of a large series over 21 years, focusing on management, surgical technique, and long-term outcomes...
  66. doi request reprint A novel controlled local drug delivery system for inner ear disease
    David P Paulson
    Department of Otorhinolaryngology Head and Neck Surgery, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA
    Laryngoscope 118:706-11. 2008
    ..This system focuses on a single local application to the inner ear via the round window membrane...
  67. ncbi request reprint Microvascular reconstruction of cranial base defects: An evaluation of complication and survival rates to justify the use of this repair
    Jason Newman
    Department of Otorhinolaryngology, Head and Neck Surgery, University of Pennsylvania, Philadelphia, PA 19104, USA
    Arch Otolaryngol Head Neck Surg 132:381-4. 2006
    ....
  68. ncbi request reprint Characterization CSMD1 in a large set of primary lung, head and neck, breast and skin cancer tissues
    Changqing Ma
    Department of Otorhinolaryngology, Head and Neck Surgery, University of Pennsylvania, Philadelphia, PA 19104, USA
    Cancer Biol Ther 8:907-16. 2009
    ..We also show that deletions of CSMD1 and aberrant splicing contribute to altered CSMD1 function in vivo...
  69. ncbi request reprint Low-grade mucoepidermoid carcinoma of the subglottis treated with organ-preservation surgery
    Daniel L Monin
    Department of Otorhinolaryngology Head and Neck Surgery Hospital of the University of Pennsylvania, Philadelphia, USA
    Ear Nose Throat J 85:332-6. 2006
    ..At follow-up 15 months postoperatively, the patient remained disease-free, and laryngeal function was intact...
  70. ncbi request reprint Identification of a gene signature for rapid screening of oral squamous cell carcinoma
    Amy F Ziober
    Department of Otorhinolaryngology Head and Neck Surgery, Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania Health System, Philadelphia, Pennsylvania 19104, USA
    Clin Cancer Res 12:5960-71. 2006
    ..e., practitioner's or dentist's office) by minimally trained personnel...
  71. ncbi request reprint Genome-wide profiling of oral squamous cell carcinoma by array-based comparative genomic hybridization
    Anthony Sparano
    Department of Otorhinolaryngology, Head and Neck, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
    Laryngoscope 116:735-41. 2006
    ..The status of 512 commonly altered cancer genes was assessed and evaluated as potential correlates of tumor behavior...
  72. ncbi request reprint Nonsurgical treatment of laryngeal cancer
    Gregory S Weinstein
    N Engl J Med 350:1049-53; author reply 1049-53. 2004
  73. ncbi request reprint Larynx preservation with supracricoid partial laryngectomy with cricohyoidoepiglottopexy. Correlation of videostroboscopic findings and voice parameters
    Gregory S Weinstein
    Department of Otorhinolaryngology Head and Neck Surgery, The University of Pennsylvania Medical Center, Philadelphia 19104, USA
    Ann Otol Rhinol Laryngol 111:1-7. 2002
    ..Patients with lower periodicity and symmetry scores tended to have lower jitter and shimmer percentages...
  74. ncbi request reprint American Society of Clinical Oncology clinical practice guideline for the use of larynx-preservation strategies in the treatment of laryngeal cancer
    David G Pfister
    American Society of Clinical Oncology, Alexandria, VA, VA 22314, USA
    J Clin Oncol 24:3693-704. 2006
    ..This guideline is intended for use by oncologists in the care of patients outside of clinical trials...
  75. ncbi request reprint Supracricoid partial laryngectomy: an organ-preservation surgery for laryngeal malignancy
    F Christopher Holsinger
    Department of Head and Neck Surgery, The University of Texas M D Anderson Cancer Center, 1515 Holcombe Boulevard, Box 441, Houston, TX, USA
    Curr Probl Cancer 29:190-200. 2005
  76. ncbi request reprint Technical refinements in the supracricoid partial laryngectomy to optimize functional outcomes
    F Christopher Holsinger
    Department of Head and Neck Surgery, The University of Texas, MD Anderson Cancer Center, Houston, TX 77030 4009, USA
    J Am Coll Surg 201:809-20. 2005
  77. ncbi request reprint Tympanomastoid suture and digastric muscle in cadaver and live parotidectomy
    Robert L Witt
    Christiana Care Health Systems, Wilmington, Delaware 19806, USA
    Laryngoscope 115:574-7. 2005
    ..To prove that the tympanomastoid suture (TMS) is a significantly closer and less variable anatomic landmark to the facial nerve than the posterior-superior margin of the posterior belly of the digastric muscle (PBD) in parotid surgery...