Research Topics
| Christopher OlsenSummaryAffiliation: University of Wisconsin Country: USA Publications
Research Grants
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Detail Information
Publications
DNA vaccination against influenza viruses: a review with emphasis on equine and swine influenzaC W Olsen
Department of Pathobiological Sciences, School of Veterinary Medicine, University of Wisconsin Madison, 2015 Linden Drive West, Madison, WI 53706, USA
Vet Microbiol 74:149-64. 2000..In addition, studies of interleukin-6 DNA co-administration in mice clearly demonstrate the potential for this approach to enhance vaccine efficacy and protection...
Triple reassortant H3N2 influenza A viruses, Canada, 2005Christopher W Olsen
Department of Pathobiological Sciences, School of Veterinary Medicin, University of Wisconsin Madison, Madison, Wisconsin 53706, USA
Emerg Infect Dis 12:1132-5. 2006..These are human/classical swine/avian reassortants similar to viruses that emerged in US pigs in 1998 but with a distinct human-lineage neuraminidase gene...
The dual DVM/MPH degree at the University of Wisconsin--Madison: a uniquely interdisciplinary collaborationChristopher W Olsen
Department of Pathobiological Sciences, School of Veterinary Medicine, University of Wisconsin Madison, Madison, WI 53706, USA
J Vet Med Educ 35:177-81. 2008..Nine MPH students over the first three years of admissions have been individuals affiliated with veterinary medicine (five DVM students and four post-graduate veterinarians)...
The emergence of novel swine influenza viruses in North AmericaChristopher W Olsen
Department of Pathobiological Sciences, School of Veterinary Medicine, University of Wisconsin Madison, 2015 Linden Drive, Madison, WI 53706, USA
Virus Res 85:199-210. 2002..Research on these novel viruses may offer important clues to the genetic basis for interspecies transmission of influenza viruses...
Serologic evidence of H1 swine Influenza virus infection in swine farm residents and employeesChristopher W Olsen
University of Wisconsin Madison, Madison, Wisconsin 53706, USA
Emerg Infect Dis 8:814-9. 2002..Because pigs can play a role in generating genetically novel influenza viruses, swine farmers may represent an important sentinel population to evaluate the emergence of new pandemic influenza viruses...
Characterization of a swine-like reassortant H1N2 influenza virus isolated from a wild duck in the United StatesChristopher W Olsen
Department of Pathobiological Sciences, School of Veterinary Medicine, University of Wisconsin Madison, 2015 Linden Drive, Madison, WI 53717, USA
Virus Res 93:115-21. 2003..The recovery of Dk/NC from a wild bird raises concerns for further widespread distribution of these H1N2 viruses via waterfowl migration...
Creating a center for global health at the University of Wisconsin-MadisonCynthia Haq
Family Medicine and Population Health Sciences, University of Wisconsin Center for Global Health, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin 53705, USA
Acad Med 83:148-53. 2008....
Acute respiratory distress syndrome and fatal interstitial pneumonia associated with equine influenza in a neonatal foalSimon F Peek
Section of Large Animal Internal Medicine, Department of Medical Sciences, School of Veterinary Medicine, University of Wisconsin, Madison, WI 53706, USA
J Vet Intern Med 18:132-4. 2004
Characterization of avian H3N3 and H1N1 influenza A viruses isolated from pigs in CanadaAlexander I Karasin
Department of Pathobiological Sciences, School of Veterinary Medicine, University of Wisconsin-Madison, 2015 Linden Dr, Madison, WI 53706, USA
J Clin Microbiol 42:4349-54. 2004..The isolation of these viruses reemphasizes the potential for interspecies transmission of influenza viruses from waterfowl to pigs in North America...
Use of real-time reverse transcriptase polymerase chain reaction assay and cell culture methods for detection of swine influenza A virusesGabriele A Landolt
Department of Pathobiological Sciences, School of Veterinary Medicine, University of Wisconsin, Madison, WI 53706, USA
Am J Vet Res 66:119-24. 2005..Some viruses were isolated in only MDCK or Mv1Lu cells, indicating that use of >1 cell line may be required to isolate a broad range of influenza A viruses...
Effects of DNA dose, route of vaccination, and coadministration of porcine interleukin-6 DNA on results of DNA vaccination against influenza virus infection in pigsDiane L Larsen
Department of Pathological Sciences, School of Veterinary Medicine, University of Wisconsin, Madison 53706, USA
Am J Vet Res 63:653-9. 2002..However, HA DNA vaccination of pigs, with or without coadministration of pIL-6 DNA, induced strong priming of the humoral immune system...
Comparison of the pathogenesis of two genetically different H3N2 influenza A viruses in pigsGabriele A Landolt
Department of Pathobiological Sciences, School of Veterinary Medicine, University of Wisconsin-Madison, 53706, USA
J Clin Microbiol 41:1936-41. 2003..In addition, infection with the triple-reassortant virus was associated with moderate to severe gross pathological and histological pulmonary lesions, while infection with the wholly human virus induced only mild pulmonary changes...
Genetic characterization of H1N2 influenza A viruses isolated from pigs throughout the United StatesAlexander I Karasin
Department of Pathobiological Sciences, School of Veterinary Medicine, University of Wisconsin, Madison 53706, USA
J Clin Microbiol 40:1073-9. 2002....
Identification of amino acids in the HA of H3 influenza viruses that determine infectivity levels in primary swine respiratory epithelial cellsMarc G Busch
Department of Pathobiological Sciences, School of Veterinary Medicine, University of Wisconsin Madison, 2015 Linden Drive, Madison, WI, USA
Virus Res 133:269-79. 2008..In particular, amino acid 138 is the dominant factor in determining infectivity levels in SRECs...
Restricted infectivity of a human-Lineage H3N2 influenza A virus in pigs is hemagglutinin and neuraminidase gene dependentGabriele A Landolt
Department of Pathobiological Sciences, School of Veterinary Medicine, University of Wisconsin-Madison, 2015 Linden Drive, Madison, WI 53706, USA
J Clin Microbiol 44:297-301. 2006..The results further support the premise that a barrier exists to human influenza virus infection in pigs, which may limit the role of pigs in pandemic virus creation through reassortment of human and avian influenza viruses...
Maternal influenza infection during pregnancy impacts postnatal brain development in the rhesus monkeySarah J Short
Department of Psychology, Harlow Center for Biological Psychology, University of Wisconsin, Madison, Wisconsin, USA
Biol Psychiatry 67:965-73. 2010..However, to verify the relevance of these findings to humans, research is needed in a primate species with more advanced prenatal corticogenesis...
Amino acid 226 in the hemagglutinin of H4N6 influenza virus determines binding affinity for alpha2,6-linked sialic acid and infectivity levels in primary swine and human respiratory epithelial cellsAllen C Bateman
Department of Pathobiological Sciences, School of Veterinary Medicine, University of Wisconsin Madison, Madison, Wisconsin 53706, USA
J Virol 82:8204-9. 2008..Using specific neuraminidases, we found that irrespective of their relative binding preferences, all of the influenza viruses examined utilized SAalpha2,6Gal to infect swine and human cells...
Identification of human H1N2 and human-swine reassortant H1N2 and H1N1 influenza A viruses among pigs in Ontario, Canada (2003 to 2005)Alexander I Karasin
Department of Pathobiological Sciences, School of Veterinary Medicine, University of Wisconsin--Madison, 2015 Linden Dr, Madison, WI 53706, USA
J Clin Microbiol 44:1123-6. 2006..These isolates demonstrate that human-lineage H1N2 viruses are infectious for pigs and that viruses with a human PB1/swine PA/swine PB2 polymerase complex can replicate in pigs...
Glycan analysis and influenza A virus infection of primary swine respiratory epithelial cells: the importance of NeuAc{alpha}2-6 glycansAllen C Bateman
Department of Pathobiological Sciences, School of Veterinary Medicine, University of Wisconsin Madison, Madison, Wisconsin 53706, USA
J Biol Chem 285:34016-26. 2010....
Swine workers and swine influenza virus infectionsGregory C Gray
University of Iowa College of Public Health, Iowa City, Iowa, USA
Emerg Infect Dis 13:1871-8. 2007..Study data suggest that swine workers and their nonswine-exposed spouses are at increased risk of zoonotic influenza virus infections...
Up to new tricks - a review of cross-species transmission of influenza A virusesGabriele A Landolt
Department of Clinical Sciences, Colorado State University, 300 West Drake Road, Fort Collins, CO 80523, USA
Anim Health Res Rev 8:1-21. 2007..This review summarizes the current knowledge of influenza ecology, and the viral factors that are thought to determine influenza A virus species specificity...
Cases of swine influenza in humans: a review of the literatureKendall P Myers
Center for Emerging Infectious Diseases, Department of Epidemiology, College of Public Health, University of Iowa, Iowa City, IA, USA
Clin Infect Dis 44:1084-8. 2007..Because prior studies have shown that persons who work with swine are at increased risk of zoonotic influenza virus infection, it is prudent to include them in pandemic planning efforts...
Transmission of equine influenza virus to dogsP C Crawford
College of Veterinary Medicine, University of Florida, Gainesville, FL 32611, USA
Science 310:482-5. 2005..Evidence of infection in pet dogs suggests that this infection may also become enzootic in this population...
Are swine workers in the United States at increased risk of infection with zoonotic influenza virus?Kendall P Myers
Center for Emerging Infectious Diseases, Department of Epidemiology, University of Iowa College of Public Health, Iowa City, IA 52242, USA
Clin Infect Dis 42:14-20. 2006..Pigs have an important role in interspecies transmission of the virus. We examined multiple swine-exposed human populations in the nation's number 1 swine-producing state for evidence of previous swine influenza virus infection...
Receptor-binding properties of swine influenza viruses isolated and propagated in MDCK cellsAlexandra S Gambaryan
Chumakov Institute of Poliomyelitis and Viral Encephalitides, Russian Academy of Medical Sciences, 142782 Moscow, Russia
Virus Res 114:15-22. 2005....
Research Grants
- Host range restriction of human influenza virusesChristopher Olsen; Fiscal Year: 2007..abstract_text> ..
- Host range restriction of human influenza virusesChristopher Olsen; Fiscal Year: 2009..abstract_text> ..
