Research Topics
Species | D B OllilaSummaryAffiliation: University of North Carolina Country: USA Publications
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Detail Information
Publications
Distance to diagnosing provider as a measure of access for patients with melanomaKaryn B Stitzenberg
Department of Surgery, School of Medicine, University of North Carolina at Chapel Hill, 3010 Old Clinic Bldg, CB 7213, Chapel Hill, NC 27599 7213, USA
Arch Dermatol 143:991-8. 2007..To examine the effect of travel distance and other sociodemographic factors on access to a diagnosing provider for patients with melanoma...
Breast cancer sentinel node metastases: histopathologic detection and clinical significanceD B Ollila
Department of Surgery, University of North Carolina at Chapel Hill, NC 27599 7210, USA
Cancer Control 8:407-14. 2001..This review addresses the handling and pathologic examination of the sentinel node (SN), the clinical significance of tumor within the SN, and the risk factors for non-SN tumor involvement...
Metastatic melanoma cells in the sentinel node cannot be ignoredDavid W Ollila
Department of Surgery, Division of Surgical Oncology and Endocrine Surgery, The University of North Carolina at Chapel Hill, Chapel Hill, NC 27599 7213, USA
J Am Coll Surg 208:924-9; discussion 929-30. 2009..We hypothesize that all patients with metastatic melanoma cells in the sentinel node have potentially life-threatening disease...
Feasibility of breast preserving therapy with single fraction in situ radiotherapy delivered intraoperativelyDavid W Ollila
Department of Surgery, UNC Lineberger Comprehensive Cancer Center, The University of North Carolina at Chapel Hill, 3010 Old Clinic Building, CB 7213, Chapel Hill, NC 27599 7213, USA
Ann Surg Oncol 14:660-9. 2007..We adapted the technique of Veronesi to deliver IORT prior to tumor excision to improve delivery to the region at risk and reduce the volume of normal tissue irradiated...
Complete metastasectomy in patients with stage IV metastatic melanomaDavid W Ollila
Division of Surgical Oncology and Endocrine Surgery, University of North Carolina at Chapel Hill School of Medicine, 3010 Old Clinic Building, Chapel Hill, NC 27599, USA
Lancet Oncol 7:919-24. 2006..This Review will present data lending support to the idea that if complete surgical metastasectomy is technically feasible, then surgery should be the first option for properly selected patients with stage IV melanoma...
Surgical management of distant metastasesDavid W Ollila
Division of Surgical Oncology and Endocrine Surgery, University of North Carolina at Chapel Hill, School of Medicine, 3010 Old Clinic Building, Chapel Hill, NC 27599 7213, USA
Surg Oncol Clin N Am 15:385-98. 2006..Until novel drug therapies show efficacy and significantly prolong survival in patients who have stage IV disease, careful consideration should be given to a complete metastectomy if technically feasible...
Lymphatic mapping and sentinel lymphadenectomy prior to neoadjuvant chemotherapy in patients with large breast cancersDavid W Ollila
Division of Surgical Oncology, Department of Surgery, University of North Carolina, Chapel Hill, NC 27599, USA
Am J Surg 190:371-5. 2005..LM/SL in patients with large breast cancers is controversial. We examined the accuracy of LM/SL prior to neoadjuvant chemotherapy in patients with large (>3.5 cm) breast cancers...
Rationale for complete metastasectomy in patients with stage IV metastatic melanomaDavid W Ollila
Division of Surgical Oncology and Endocrine Surgery, The University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, North Carolina, USA
J Surg Oncol 104:420-4. 2011..This review article will present data supporting the position that if a complete metastasectomy is technically feasible, then surgery should be strongly considered the first option for properly selected patients with stage IV melanoma...
Axillary lymph node count is lower after neoadjuvant chemotherapyHeather Neuman
Department of Surgery, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA
Am J Surg 191:827-9. 2006..6/170 or 4%, P = .003). CONCLUSIONS: A low lymph node count is more common in patients after treatment with neoadjuvant chemotherapy and should not be assumed to represent an incomplete ALND...
Indications for lymphatic mapping and sentinel lymphadenectomy in patients with thin melanoma (Breslow thickness < or =1.0 mm)Karyn B Stitzenberg
Division of Surgical Oncology, Department of Surgery, 3010 Old Clinic Building, CB#7213, University of North Carolina, Chapel Hill, NC 27599-7213, USA
Ann Surg Oncol 11:900-6. 2004....
Extracapsular extension of the sentinel lymph node metastasis: a predictor of nonsentinel node tumor burdenKaryn B Stitzenberg
Department of Surgery, University of North Carolina, 3010 Old Clinic Building, Chapel Hill, NC 27599, USA
Ann Surg 237:607-12; discussion 612-3. 2003..CONCLUSIONS: ECE of the SN metastasis is a strong predictor of NSN tumor involvement. All patients with ECE of the SN metastasis should undergo mandatory completion ALND...
In vivo intraoperative radiotherapy: a novel approach to radiotherapy for early stage breast cancerKaryn B Stitzenberg
Department of Surgery, University of North Carolina, Chapel Hill, NC, USA
Ann Surg Oncol 14:1515-6. 2007..We are investigating the feasibility of partial breast irradiation using a single fraction of IORT delivered to the tumor in vivo prior to surgical resection...
Influence of provider and practice characteristics on melanoma careKaryn B Stitzenberg
Department of Surgery, University of North Carolina, 3010 Old Clinic Building, CB 7213, Chapel Hill, NC 27599 7213, USA
Am J Surg 193:206-12. 2007..The purpose of this study is to describe the structure of melanoma care in North Carolina by examining services provided by different providers and the overall coordination of care...
The triple negative paradox: primary tumor chemosensitivity of breast cancer subtypesLisa A Carey
Division of Hematology Oncology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599 7305, USA
Clin Cancer Res 13:2329-34. 2007..Gene expression analysis identifies several breast cancer subtypes. We examined the relationship of neoadjuvant chemotherapy response to outcome among these breast cancer subtypes...
Number of nevi and early-life ambient UV exposure are associated with BRAF-mutant melanomaNancy E Thomas
Department of Dermatology, University of North Carolina, Chapel Hill, NC 27599, USA
Cancer Epidemiol Biomarkers Prev 16:991-7. 2007..The association of BRAF mutations with early-life UV exposure provides evidence in support of childhood sun protection for melanoma prevention...
Method of detection of initial recurrence of stage II/III cutaneous melanoma: analysis of the utility of follow-up stagingMichael O Meyers
Department of Surgery and The Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599 7213, USA
Ann Surg Oncol 16:941-7. 2009..The purpose of this study was to determine the impact of routine imaging on the method of detection of first recurrence in patients with stage II and sentinel lymph node-positive stage III melanoma...
Postoperative hypocalcemia after parathyroidectomy for renal hyperparathyroidism in the era of cinacalcetMichael O Meyers
Department of Surgery, University of North Carolina School of Medicine at Chapel Hill, CB 7213, 105 Manning Drive, P O Box 1031, Chapel Hill, NC 27599 7213, USA
Am Surg 75:843-7. 2009..This may be useful to inform physicians and patients of expectations postoperatively, although it is not likely to alter management...
Age and Breslow depth are associated with a positive sentinel lymph node in patients with cutaneous melanocytic tumors of uncertain malignant potentialMichael O Meyers
Department of Surgery, University of North Carolina School of Medicine at Chapel Hill, Chapel Hill, NC 27599 7213, USA
J Am Coll Surg 211:744-8. 2010..However, it is unclear whether this is required in all patients. We present our experience with sentinel lymphadenectomy in these patients and examine the clinical and pathologic variables associated with a positive SLN...
Long-term outcome of neoadjuvant therapy for locally advanced breast carcinoma: effective clinical downstaging allows breast preservation and predicts outstanding local control and survivalWilliam G Cance
Department of Surgery, Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, 27599, USA
Ann Surg 236:295-302; discussion 302-3. 2002..The authors determined the rate of breast preservation, the disease-free and overall survival, and the factors associated with locoregional and distant recurrent disease...
Tandem BRAF mutations in primary invasive melanomasNancy E Thomas
Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, North Carolina, USA
J Invest Dermatol 122:1245-50. 2004..The finding of tandem mutations in thin melanomas makes it more likely that they arise as a simultaneous rather than sequential event...
Staged sentinel lymph node biopsy before mastectomy facilitates surgical planning for breast cancer patientsNancy Klauber-Demore
Division of Surgical Oncology, University of North Carolina at Chapel Hill, 3010 Old Clinic Bldg, CB No 7213, Chapel Hill, NC 27599, USA
Am J Surg 190:595-7. 2005..The purpose of this study was to determine how performing an SLN biopsy (SLNB) before the definitive operation would influence subsequent surgical procedures...
High-resolution axillary ultrasound is a poor prognostic test for determining pathologic lymph node status in patients undergoing neoadjuvant chemotherapy for locally advanced breast cancerNancy Klauber-Demore
Department of Surgery, University of North Carolina at Chapel Hill, 3010 Old Clinic Bldg, CB No 7213, Chapel Hill, NC 27599, USA
Am J Surg 188:386-9. 2004..The purpose of this study was to evaluate the efficacy of high-resolution axillary ultrasound in detecting axillary lymph node metastases after neoadjuvant chemotherapy in patients with locally advanced breast cancer...
Cutaneous melanoma: update on prevention, screening, diagnosis, and treatmentErika L Rager
Department of Surgery, University of North Carolina at Chapel Hill, School of Medicine, Chapel Hill, North Carolina, USA
Am Fam Physician 72:269-76. 2005..Preventive strategies for melanoma should emphasize seeking shade when outdoors, wearing protective clothing, and avoiding exposure during the peak sunlight hours...
Size of residual lymph node metastasis after neoadjuvant chemotherapy in locally advanced breast cancer patients is prognosticNancy Klauber-Demore
Department of Surgery, University of North Carolina at Chapel Hill, 27599, USA
Ann Surg Oncol 13:685-91. 2006..We examined the residual lymph node metastasis size in patients after treatment with neoadjuvant chemotherapy to determine the relevance of metastasis size on outcome...
Population-based analysis of lymphatic mapping and sentinel lymphadenectomy utilization for intermediate thickness melanomaKaryn B Stitzenberg
Department of Surgery, University of North Carolina, Chapel Hill, North Carolina 2755 7590, USA
J Surg Oncol 93:100-7; discussion 107-8. 2006..We hypothesize that a significant portion of these patients are not undergoing LM/SL. We explore factors that influence use of LM/SL...
American Joint Committee on Cancer tumor-node-metastasis stage after neoadjuvant chemotherapy and breast cancer outcomeLisa A Carey
Division of Hematology Oncology, Department of Medicine, University of North Carolina, Chapel Hill, NC 27599 7305, USA
J Natl Cancer Inst 97:1137-42. 2005....
Cytokeratin immunohistochemical validation of the sentinel node hypothesis in patients with breast cancerKaryn B Stitzenberg
Department of Surgery, University of North Carolina, Chapel Hill 27599, USA
Am J Clin Pathol 117:729-37. 2002..node most likely to harbor metastatic tumor Standardization of the handling, sectioning, and staining of the SN is necessary as lymphatic mapping and sentinel lymphadenectomy become integrated into the care of patients with breast cancer..
Experienced radio-guided surgery teams can successfully perform minimally invasive radio-guided parathyroidectomy without intraoperative parathyroid hormone assaysAbigail S Caudle
Department of Surgery, University of North Carolina, Chapel Hill, USA
Am Surg 72:785-9; discussion 790. 2006..This correlates with reported success rates of 95 per cent to 100 per cent using iPTH. We conclude that minimally invasive parathyroidectomy can be successfully performed without using iPTH assays...
Successful minimally invasive parathyroidectomy for primary hyperparathyroidism without using intraoperative parathyroid hormone assaysDavid W Ollila
Division of Surgical Oncology, University of North Carolina, 3010 Old Clinic Building, CB #7213, Chapel Hill, NC 27599, USA
Am J Surg 191:52-6. 2006..We conclude that MIP can be performed successfully without using iPTH assays...
Prophylaxis and screening options: recommendations for young women with BRCA mutationsJonathan C Samuel
Division of Surgical Oncology, University of North Carolina at Chapel Hill, 3010 Old Clinic Building, CB 7213, 27599-7213, USA
Breast Dis 23:31-5. 2005....
Prolonged survival after complete resection of disseminated melanoma and active immunotherapy with a therapeutic cancer vaccineEddy C Hsueh
Sonya Valley Ghidossi Vaccine Laboratory, John Wayne Cancer Institute, Santa Monica, CA 90404, USA
J Clin Oncol 20:4549-54. 2002..These findings suggest that adjuvant active specific immunotherapy should be considered after cytoreductive surgery for advanced melanoma...
Sentinel lymph node biopsy during pregnancy: initial clinical experienceMatthew M Mondi
Surgical Oncology Services, Wake Forest University, Winston Salem, North Carolina, USA
Ann Surg Oncol 14:218-21. 2007....
Phase I pilot clinical trial of human IgM monoclonal antibody to ganglioside GM3 in patients with metastatic melanomaReiko F Irie
Department of Biotechnology Sciences, John Wayne Cancer Institute, Saint John s Health Center, 2200 Santa Monica Blvd, CA 90404, Santa Monica, USA
Cancer Immunol Immunother 53:110-7. 2004..All patients received a 48-h continuous infusion of L612 HuMAb at a dose of 960 mg, 1,440 mg, or 1,920 mg. Five of these patients received a second infusion and one patient received a third infusion, all with the previous dose...
