Alison Oliveto

Summary

Affiliation: University of Arkansas for Medical Sciences
Country: USA

Publications

  1. pmc Effects of prototypic calcium channel blockers in methadone-maintained humans responding under a naloxone discrimination procedure
    Alison Oliveto
    Department of Psychiatry and Behavioral Sciences, University of Arkansas for Medical Sciences, 4301 W Markham St, Little Rock, AR 72205, USA
    Eur J Pharmacol 715:424-35. 2013
  2. ncbi request reprint Efficacy of dose and contingency management procedures in LAAM-maintained cocaine-dependent patients
    Alison Oliveto
    Department of Psychiatry, Yale School of Medicine and the VA CT Healthcare System, West Haven, CT, USA
    Drug Alcohol Depend 79:157-65. 2005
  3. pmc Sertraline delays relapse in recently abstinent cocaine-dependent patients with depressive symptoms
    Alison Oliveto
    University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA
    Addiction 107:131-41. 2012
  4. pmc Randomized, double blind, placebo-controlled trial of disulfiram for the treatment of cocaine dependence in methadone-stabilized patients
    Alison Oliveto
    Psychiatry Dept, University of Arkansas for Medical Sciences, Slot 843, 4301 W Markham St, Little Rock, AR 72205, USA
    Drug Alcohol Depend 113:184-91. 2011
  5. pmc Behavioral effects of gamma-hydroxybutyrate in humans
    Alison Oliveto
    Department of Psychiatry and Behavioral Sciences, University of Arkansas for Medical Sciences, 4301 W Markham St, Little Rock, AR 72205, USA
    Behav Pharmacol 21:332-42. 2010
  6. ncbi request reprint Desipramine and contingency management for cocaine and opiate dependence in buprenorphine maintained patients
    Thomas Kosten
    Department of Psychiatry, Yale University School of Medicine, VA New England MIRECC, VA Caonnecticut Healthcare System, 950 Campbell Avenue, Bldg 35, West Haven, CT 06516, USA
    Drug Alcohol Depend 70:315-25. 2003
  7. ncbi request reprint Clinical efficacy of citalopram alone or augmented with bupropion in methadone-stabilized patients
    James Poling
    Yale University School of Medicine, VA Connecticut Healthcare System, West Haven, CT 06516, USA
    Am J Addict 16:187-94. 2007
  8. ncbi request reprint Comorbid major depressive disorder as a prognostic factor in cocaine-abusing buprenorphine-maintained patients treated with desipramine and contingency management
    Gerardo Gonzalez
    Department of Psychiatry, Yale University School of Medicine, and VA Connecticut Healthcare System, West Haven, Connecticut 06516, USA
    Am J Drug Alcohol Abuse 29:497-514. 2003
  9. ncbi request reprint Clinical efficacy of gabapentin versus tiagabine for reducing cocaine use among cocaine dependent methadone-treated patients
    Gerardo Gonzalez
    Department of Psychiatry, Yale University, New Haven, CT 06511, USA
    Drug Alcohol Depend 87:1-9. 2007
  10. ncbi request reprint Tiagabine increases cocaine-free urines in cocaine-dependent methadone-treated patients: results of a randomized pilot study
    Gerardo Gonzalez
    Department of Psychiatry, Yale University School of Medicine, West Haven, CT, USA
    Addiction 98:1625-32. 2003

Research Grants

  1. Opioid Antagonist Discrimination: A Model of Withdrawal
    ALISON OLIVETO BEAUDOIN; Fiscal Year: 2007
  2. Disulfiram for Cocaine Abuse in Methadone - Patients
    ALISON OLIVETO BEAUDOIN; Fiscal Year: 2007
  3. Disulfiram for Cocaine Abuse in Metadone - Patients
    Alison Oliveto; Fiscal Year: 2010
  4. Disulfiram for Cocaine Abuse in Methadone- Patients
    ALISON OLIVETO BEAUDOIN; Fiscal Year: 2005
  5. Behavioral Effects of GHB in Healthy Volunteers
    ALISON OLIVETO BEAUDOIN; Fiscal Year: 2003
  6. Opioid Antagonist Discrimination: A Model of Withdrawal
    Alison Oliveto; Fiscal Year: 2011

Detail Information

Publications28

  1. pmc Effects of prototypic calcium channel blockers in methadone-maintained humans responding under a naloxone discrimination procedure
    Alison Oliveto
    Department of Psychiatry and Behavioral Sciences, University of Arkansas for Medical Sciences, 4301 W Markham St, Little Rock, AR 72205, USA
    Eur J Pharmacol 715:424-35. 2013
    ..These results suggest that CCBs with different chemical structures can be differentiated behaviorally, and that diltiazem and verapamil do not attenuate the discriminative stimulus effects of naloxone in humans at the doses tested...
  2. ncbi request reprint Efficacy of dose and contingency management procedures in LAAM-maintained cocaine-dependent patients
    Alison Oliveto
    Department of Psychiatry, Yale School of Medicine and the VA CT Healthcare System, West Haven, CT, USA
    Drug Alcohol Depend 79:157-65. 2005
    ..These results suggest that an efficacious maintenance dose is necessary for contingencies to be effective in facilitating both opioid and cocaine abstinence...
  3. pmc Sertraline delays relapse in recently abstinent cocaine-dependent patients with depressive symptoms
    Alison Oliveto
    University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA
    Addiction 107:131-41. 2012
    ..Whether the selective serotonin re-uptake inhibitor sertraline at 200 mg/day delays relapse in recently abstinent cocaine-dependent individuals...
  4. pmc Randomized, double blind, placebo-controlled trial of disulfiram for the treatment of cocaine dependence in methadone-stabilized patients
    Alison Oliveto
    Psychiatry Dept, University of Arkansas for Medical Sciences, Slot 843, 4301 W Markham St, Little Rock, AR 72205, USA
    Drug Alcohol Depend 113:184-91. 2011
    ..This study examined the dose-related efficacy of disulfiram for treating cocaine dependence in methadone-stabilized cocaine dependent participants...
  5. pmc Behavioral effects of gamma-hydroxybutyrate in humans
    Alison Oliveto
    Department of Psychiatry and Behavioral Sciences, University of Arkansas for Medical Sciences, 4301 W Markham St, Little Rock, AR 72205, USA
    Behav Pharmacol 21:332-42. 2010
    ..These initial findings suggest that GHB at doses of 0.32-3.2 g/70 kg produces dissociative, sedating and some stimulant-like effects in humans without a history of sedative abuse...
  6. ncbi request reprint Desipramine and contingency management for cocaine and opiate dependence in buprenorphine maintained patients
    Thomas Kosten
    Department of Psychiatry, Yale University School of Medicine, VA New England MIRECC, VA Caonnecticut Healthcare System, 950 Campbell Avenue, Bldg 35, West Haven, CT 06516, USA
    Drug Alcohol Depend 70:315-25. 2003
    ..DMI and CM had independent and additive effects in facilitating cocaine-free urines in buprenorphine maintained patients. The antidepressant appeared to enhance responsiveness to CM reinforcement...
  7. ncbi request reprint Clinical efficacy of citalopram alone or augmented with bupropion in methadone-stabilized patients
    James Poling
    Yale University School of Medicine, VA Connecticut Healthcare System, West Haven, CT 06516, USA
    Am J Addict 16:187-94. 2007
    ..The results indicate that neither citalopram nor citalopram augmented with bupropion were more effective than placebo in the treatment of opioid abuse...
  8. ncbi request reprint Comorbid major depressive disorder as a prognostic factor in cocaine-abusing buprenorphine-maintained patients treated with desipramine and contingency management
    Gerardo Gonzalez
    Department of Psychiatry, Yale University School of Medicine, and VA Connecticut Healthcare System, West Haven, Connecticut 06516, USA
    Am J Drug Alcohol Abuse 29:497-514. 2003
    ..The ND cocaine-abusing, opiate-dependent patients may be more responsive to the anticraving effects of DMI...
  9. ncbi request reprint Clinical efficacy of gabapentin versus tiagabine for reducing cocaine use among cocaine dependent methadone-treated patients
    Gerardo Gonzalez
    Department of Psychiatry, Yale University, New Haven, CT 06511, USA
    Drug Alcohol Depend 87:1-9. 2007
    ..GABAergic medications appear to reduce the reinforcing effects of cocaine by attenuating cocaine-induced dopamine release. This study evaluated gabapentin and tiagabine compared to placebo in reducing cocaine taking behavior...
  10. ncbi request reprint Tiagabine increases cocaine-free urines in cocaine-dependent methadone-treated patients: results of a randomized pilot study
    Gerardo Gonzalez
    Department of Psychiatry, Yale University School of Medicine, West Haven, CT, USA
    Addiction 98:1625-32. 2003
    ..We sought to evaluate the safety and efficacy of the GABAergic agent tiagabine in reducing cocaine use among methadone-treated patients...
  11. ncbi request reprint Desipramine treatment for cocaine dependence in buprenorphine- or methadone-treated patients: baseline urine results as predictor of response
    Thomas Kosten
    Department of Psychiatry, Yale University School of Medicine, VA Connecticut Healthcare System, West Haven, CT 06516, USA
    Am J Addict 14:8-17. 2005
    ..The CU+ patients showed a treatment effect of DMI. This DMI effect was significant in patients maintained on BUP but not on Meth...
  12. pmc Sex and opioid maintenance dose influence response to naloxone in opioid-dependent humans: a retrospective analysis
    Mohit P Chopra
    Department of Psychiatry and Behavioral Sciences, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA
    Pharmacol Biochem Behav 90:787-96. 2008
    ..These results suggest that those on a lower MMD, especially women, experience a more intense, but short-lived, response to naloxone, whereas those on a higher MMD experience a more modest, but longer-lasting effect...
  13. ncbi request reprint Depression predicts higher rates of heroin use on desipramine with buprenorphine than with methadone
    Thomas Kosten
    Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA
    Am J Addict 13:191-201. 2004
    ..Cocaine-free urines showed no association with depression. This poor outcome with desipramine and buprenorphine suggests that this medication combination is not indicated in depressed opioid-dependent patients...
  14. ncbi request reprint Progesterone effects on cocaine use in male cocaine users maintained on methadone: a randomized, double-blind, pilot study
    Mehmet Sofuoglu
    Department of Psychiatry, Yale University School of Medicine, Veterans Affairs Connecticut Healthcare System, Connecticut, USA
    Exp Clin Psychopharmacol 15:453-60. 2007
    ..60 vs. 0.73; U=4837, p<.04). These preliminary findings do not support the efficacy of progesterone in male cocaine users. The efficacy of progesterone in female cocaine users remains to be determined in future studies...
  15. ncbi request reprint Utility of crossover designs in clinical trials: efficacy of desipramine vs. placebo in opioid-dependent cocaine abusers
    Alan Feingold
    Department of Psychiatry, Yale University School of Medicine, VA Connecticut Healthcare System, West Haven 06516, USA
    Am J Addict 11:111-23. 2002
    ....
  16. ncbi request reprint Isradipine and dextromethorphan in methadone-maintained humans under a naloxone discrimination procedure
    Alison Oliveto
    CT and VA Connecticut Healthcare System, Yale University, New Haven, 950 Campbell Avenue, Psychiatry 116A 4, Building 36, West Haven, CT 06516, USA
    Eur J Pharmacol 491:157-68. 2004
    ..These results suggest that isradipine attenuates and dextromethorphan enhances some of the behavioral effects of naloxone in opioid-dependent humans...
  17. ncbi request reprint Ketoconazole increases cocaine and opioid use in methadone maintained patients
    Thomas R Kosten
    Department of Psychiatry 151D, Yale University School of Medicine, VA Connecticut Healthcare System, West Haven, CT 06516, USA
    Drug Alcohol Depend 66:173-80. 2002
    ..Thus, in agreement with the negative results from acute dosing studies in primates and humans, chronic ketoconazole treatment does not appear to reduce cocaine or opioid use in humans maintained on methadone...
  18. doi request reprint Clinical efficacy of sertraline alone and augmented with gabapentin in recently abstinent cocaine-dependent patients with depressive symptoms
    Michael J Mancino
    From the Department of Psychiatry, University of Arkansas for Medical Sciences, Little Rock, AR Department of Psychiatry, VA Boston Healthcare System, Brockton, MA Department of Biostatistics, University of Arkansas for Medical Sciences, Little Rock, AR and Department of Psychiatry, Baylor College of Medicine and Michael E DeBakey VA Medical Center, Houston, TX
    J Clin Psychopharmacol 34:234-9. 2014
    ..This study's aim was to determine if treatment with sertraline (SERT) or SERT plus gabapentin (GBP) improved treatment retention, depressive symptoms, and/or cocaine use...
  19. ncbi request reprint Effects of reducing contingency management values on heroin and cocaine use for buprenorphine- and desipramine-treated patients
    Thomas Kosten
    Department of Psychiatry, Yale University School of Medicine, VA New England MIRECC, West Haven, CT 06516, USA
    Addiction 98:665-71. 2003
    ..The 'escalating CM' was eliminated during months 4-6 to assess any reduction in drug-free urines...
  20. ncbi request reprint D-cycloserine-Naloxone interactions in opioid-dependent humans under a novel-response naloxone discrimination procedure
    Alison Oliveto
    Department of Psychiatry, Yale School of Medicine and Veterans Affairs Connecticut Healthcare System, West Haven, Connecticut 06516, USA
    Exp Clin Psychopharmacol 11:237-46. 2003
    ..Naloxone attenuated D-cycloserine-induced increases in systolic blood pressure. These results suggest that D-cycloserine at doses up to 500 mg/70 kg may have some limited usefulness in relieving symptoms of opioid withdrawal...
  21. pmc Effect of PTSD diagnosis and contingency management procedures on cocaine use in dually cocaine- and opioid-dependent individuals maintained on LAAM: a retrospective analysis
    Michael J Mancino
    Department of Psychiatry, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA
    Am J Addict 19:169-77. 2010
    ..This suggests that CM may help improve the potentially worse outcomes in opioid- and cocaine-dependent individuals with PTSD compared to those without PTSD. (Am J Addict 2010;00:1-9)...
  22. ncbi request reprint Effects of naltrexone and isradipine, alone or in combination, on cocaine responses in humans
    Mehmet Sofuoglu
    Department of Psychiatry, School of Medicine, Yale University, New Haven, CT, USA
    Pharmacol Biochem Behav 75:801-8. 2003
    ..These results suggest that isradipine alone or in combination with naltrexone attenuates some of the physiological effects of cocaine...
  23. pmc Characterizing methamphetamine withdrawal in recently abstinent methamphetamine users: a pilot field study
    Michael J Mancino
    Department of Psychiatry, Psychiatric Research Institute, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA
    Am J Drug Alcohol Abuse 37:131-6. 2011
    ..Methamphetamine dependence has become a significant problem, but methamphetamine withdrawal symptoms have not been well studied...
  24. ncbi request reprint Combating opiate dependence: a comparison among the available pharmacological options
    Gerardo Gonzalez
    Department of Psychiatry, Yale University School of Medicine, West Haven, CT 06516, USA
    Expert Opin Pharmacother 5:713-25. 2004
    ....
  25. ncbi request reprint Cue-induced brain activity changes and relapse in cocaine-dependent patients
    Thomas R Kosten
    Department of Psychiatry, Yale University School of Medicine, VA Connecticut Healthcare System, West Haven, CT 06516, USA
    Neuropsychopharmacology 31:644-50. 2006
    ..This physiological activation was a better predictor of relapse than subjective reports of craving, and may be a useful target for treatment development...
  26. ncbi request reprint Treatment of heroin (diamorphine) addiction: current approaches and future prospects
    Gerardo Gonzalez
    Department of Psychiatry, Division of Substance Abuse, Yale University School of Medicine, VA Connecticut Healthcare System, West Haven, Connecticut 06516, USA
    Drugs 62:1331-43. 2002
    ..This new approach may facilitate the expansion of treatment while reducing the potential for medication diversion and intravenous use...
  27. pmc Effects of Disulfiram on QTc Interval in Non-Opioid-Dependent and Methadone-Treated Cocaine-Dependent Patients
    Thomas S Atkinson
    From the Department of Psychiatry and Behavioral Sciences, College of Medicine, University of Arkansas for Medical Sciences, Little Rock
    J Addict Med 7:243-8. 2013
    ..Thus, the effects of disulfiram on QTc interval in a subset of cocaine-dependent patients participating in a 14-week, randomized, double-blind, placebo-controlled clinical trial of disulfiram were prospectively determined...
  28. ncbi request reprint Butorphanol and nalbuphine in opioid-dependent humans under a naloxone discrimination procedure
    Alison Oliveto
    Substance Abuse Center, Department of Psychiatry, Yale University School of Medicine, 34 Park Street, New Haven, CT 06519, USA
    Pharmacol Biochem Behav 71:85-96. 2002
    ..These results suggest that mixed-action opioid agonist/antagonists may be distinguished from the opioid antagonist naloxone based on their discriminative-stimulus effects under a novel-response naloxone discrimination procedure...

Research Grants21

  1. Opioid Antagonist Discrimination: A Model of Withdrawal
    ALISON OLIVETO BEAUDOIN; Fiscal Year: 2007
    ..This paradigm provides a sensitive, standard, objective, systematic method to identify potential agents for enhancing OW treatment which can be examined further in a detox protocol. ..
  2. Disulfiram for Cocaine Abuse in Methadone - Patients
    ALISON OLIVETO BEAUDOIN; Fiscal Year: 2007
    ..The prognostic relevance of other factors (e.g., sex, discounting behavior) will also be examined. ..
  3. Disulfiram for Cocaine Abuse in Metadone - Patients
    Alison Oliveto; Fiscal Year: 2010
    ..The prognostic relevance of other factors (e.g., sex, discounting behavior) will also be examined. ..
  4. Disulfiram for Cocaine Abuse in Methadone- Patients
    ALISON OLIVETO BEAUDOIN; Fiscal Year: 2005
    ..The prognostic relevance of genotype at the dopamine beta-hydroxylase locus, dopamine beta-hydroxylase enzyme activity, and severity of cocaine dependence will also be examined. ..
  5. Behavioral Effects of GHB in Healthy Volunteers
    ALISON OLIVETO BEAUDOIN; Fiscal Year: 2003
    ..This study will also potentially establish a standard methodology to characterize systematically the behavioral effects of GHB in humans. ..
  6. Opioid Antagonist Discrimination: A Model of Withdrawal
    Alison Oliveto; Fiscal Year: 2011
    ..This paradigm provides a sensitive, standard, objective, systematic method to identify potential agents for enhancing OW treatment which can be examined further in a detox protocol. ..