DANIEL S O'LEARY

Summary

Affiliation: University of Iowa
Country: USA

Publications

  1. ncbi request reprint Effects of smoking marijuana on focal attention and brain blood flow
    DANIEL S O'LEARY
    Department of Psychiatry, Roy J and Lucille A Carver College of Medicine, The University of Iowa, Iowa 52242, USA
    Hum Psychopharmacol 22:135-48. 2007
  2. ncbi request reprint Marijuana alters the human cerebellar clock
    DANIEL S O'LEARY
    Department of Psychiatry, University of Iowa Hospital and Clinic, Iowa City, IA 52242, USA
    Neuroreport 14:1145-51. 2003
  3. ncbi request reprint Effects of smoking marijuana on brain perfusion and cognition
    DANIEL S O'LEARY
    Mental Health Clinical Research Center, University of Iowa College of Medicine, Iowa City, IA 52242 1057, USA
    Neuropsychopharmacology 26:802-16. 2002
  4. pmc Theory of mind and schizophrenia: a positron emission tomography study of medication-free patients
    Nancy C Andreasen
    Department of Psychiatry, The University of Iowa Carver College of Medicine, 200 Hawkins Drive, Room W278GH, Iowa City, IA 52242 1057, USA
    Schizophr Bull 34:708-19. 2008
  5. ncbi request reprint Effects of frequent marijuana use on memory-related regional cerebral blood flow
    Robert I Block
    Department of Anesthesia, University of Iowa, Room 5140, Westlawn Building, Iowa City, IA 52242, USA
    Pharmacol Biochem Behav 72:237-50. 2002
  6. pmc Cognitive and magnetic resonance imaging brain morphometric correlates of brain-derived neurotrophic factor Val66Met gene polymorphism in patients with schizophrenia and healthy volunteers
    Beng Choon Ho
    Department of Psychiatry, Roy J and Lucille A Carver College of Medicine, University of Iowa, Iowa City, USA
    Arch Gen Psychiatry 63:731-40. 2006
  7. ncbi request reprint Emotions in unmedicated patients with schizophrenia during evaluation with positron emission tomography
    Sergio Paradiso
    Mental Health Clinical Research Center, Dapartment of Psychiatry, Univeristy of Iowa College of Medicine, Iowa City, IA 52242 1057, USA
    Am J Psychiatry 160:1775-83. 2003
  8. ncbi request reprint Cerebral blood flow changes associated with Schneiderian first-rank symptoms in schizophrenia
    Nicolas Franck
    Mental Health Clinical Research Center, Department of Psychiatry, University of Iowa College of Medicine, Iowa City, Iowa, USA
    J Neuropsychiatry Clin Neurosci 14:277-82. 2002
  9. doi request reprint Eyeblink conditioning in healthy adults: a positron emission tomography study
    Krystal L Parker
    Department of Psychiatry, Roy J and Lucille A Carver College of Medicine, University of Iowa, Iowa City, IA, 52242, USA
    Cerebellum 11:946-56. 2012
  10. pmc The neural correlates of implicit sequence learning in schizophrenia
    Cherie L Marvel
    Department of Psychiatry, Roy J and Lucille A Carver College of Medicine, University of Iowa, USA
    Neuropsychology 21:761-77. 2007

Collaborators

Detail Information

Publications15

  1. ncbi request reprint Effects of smoking marijuana on focal attention and brain blood flow
    DANIEL S O'LEARY
    Department of Psychiatry, Roy J and Lucille A Carver College of Medicine, The University of Iowa, Iowa 52242, USA
    Hum Psychopharmacol 22:135-48. 2007
    ..These data indicate that marijuana has dramatic direct effects on rCBF, but causes relatively little change in the normal pattern of task-related rCBF on this auditory focused attention task...
  2. ncbi request reprint Marijuana alters the human cerebellar clock
    DANIEL S O'LEARY
    Department of Psychiatry, University of Iowa Hospital and Clinic, Iowa City, IA 52242, USA
    Neuroreport 14:1145-51. 2003
    ..Smoking marijuana appears to accelerate a cerebellar clock altering self-paced behaviors...
  3. ncbi request reprint Effects of smoking marijuana on brain perfusion and cognition
    DANIEL S O'LEARY
    Mental Health Clinical Research Center, University of Iowa College of Medicine, Iowa City, IA 52242 1057, USA
    Neuropsychopharmacology 26:802-16. 2002
    ..There was no significant rCBF change in the nucleus accumbens or other reward-related brain regions, nor in basal ganglia or hippocampus, which have a high density of cannabinoid receptors...
  4. pmc Theory of mind and schizophrenia: a positron emission tomography study of medication-free patients
    Nancy C Andreasen
    Department of Psychiatry, The University of Iowa Carver College of Medicine, 200 Hawkins Drive, Room W278GH, Iowa City, IA 52242 1057, USA
    Schizophr Bull 34:708-19. 2008
    ..This capacity, critical for social competence, is impaired in schizophrenia. We undertook a study of TOM in a group of patients with schizophrenia and healthy controls...
  5. ncbi request reprint Effects of frequent marijuana use on memory-related regional cerebral blood flow
    Robert I Block
    Department of Anesthesia, University of Iowa, Room 5140, Westlawn Building, Iowa City, IA 52242, USA
    Pharmacol Biochem Behav 72:237-50. 2002
    ..These findings indicate altered memory-related brain function in marijuana users...
  6. pmc Cognitive and magnetic resonance imaging brain morphometric correlates of brain-derived neurotrophic factor Val66Met gene polymorphism in patients with schizophrenia and healthy volunteers
    Beng Choon Ho
    Department of Psychiatry, Roy J and Lucille A Carver College of Medicine, University of Iowa, Iowa City, USA
    Arch Gen Psychiatry 63:731-40. 2006
    ..Its role in determining cognitive deficits in schizophrenia has also not been systematically studied...
  7. ncbi request reprint Emotions in unmedicated patients with schizophrenia during evaluation with positron emission tomography
    Sergio Paradiso
    Mental Health Clinical Research Center, Dapartment of Psychiatry, Univeristy of Iowa College of Medicine, Iowa City, IA 52242 1057, USA
    Am J Psychiatry 160:1775-83. 2003
    ..The authors measured regional cerebral blood flow (rCBF) during performance of a task that required unmedicated patients to recognize the emotional valence of visual images and to determine whether they were pleasant or unpleasant...
  8. ncbi request reprint Cerebral blood flow changes associated with Schneiderian first-rank symptoms in schizophrenia
    Nicolas Franck
    Mental Health Clinical Research Center, Department of Psychiatry, University of Iowa College of Medicine, Iowa City, Iowa, USA
    J Neuropsychiatry Clin Neurosci 14:277-82. 2002
    ..The results of this study demonstrate a cerebral pattern of activation related to Schneiderian symptoms and reinforce the hypothesis of an involvement of cortical areas that mediate space and body representation in such phenomena...
  9. doi request reprint Eyeblink conditioning in healthy adults: a positron emission tomography study
    Krystal L Parker
    Department of Psychiatry, Roy J and Lucille A Carver College of Medicine, University of Iowa, Iowa City, IA, 52242, USA
    Cerebellum 11:946-56. 2012
    ..Specifically, large peaks were noted in cerebellar lobules IV/V, the frontal lobes, and cingulate gyri...
  10. pmc The neural correlates of implicit sequence learning in schizophrenia
    Cherie L Marvel
    Department of Psychiatry, Roy J and Lucille A Carver College of Medicine, University of Iowa, USA
    Neuropsychology 21:761-77. 2007
    ..This adaptive strategy facilitated sequence learning but may have interfered with conventional implicit learning of the overall stimulus pattern...
  11. ncbi request reprint Age and regional cerebral blood flow in schizophrenia: age effects in anterior cingulate, frontal, and parietal cortex
    Susan K Schultz
    Department of Radiology, University of Iowa College of Medicine, Iowa City, Iowa 52242 1000, USA
    J Neuropsychiatry Clin Neurosci 14:19-24. 2002
    ..In contrast, the reduced flow observed in the frontal and parietal regions may be unique to schizophrenia...
  12. ncbi request reprint Untreated initial psychosis: relation to cognitive deficits and brain morphology in first-episode schizophrenia
    Beng Choon Ho
    Mental Health Clinical Research Center, Department of Psychiatry, University of Iowa College of Medicine and the University of Iowa College of Public Health, Iowa City, IA 52242, USA
    Am J Psychiatry 160:142-8. 2003
    ..This study investigated the relationships between duration of untreated initial psychosis and neurocognitive functioning and high-resolution imaging brain measurements...
  13. pmc Effects of chronic marijuana use on brain activity during monetary decision-making
    Jatin G Vaidya
    Department of Psychiatry, University of Iowa Hospitals and Clinics, Iowa City, IA 52242, USA
    Neuropsychopharmacology 37:618-29. 2012
    ..Thus, chronic MJ users tend to strongly recruit neural circuitry involved in decision-making and reward processing (vmPFC), and probabilistic learning (cerebellum) when performing the IGT...
  14. pmc Neural sensitivity to absolute and relative anticipated reward in adolescents
    Jatin G Vaidya
    Department of Psychiatry, University of Iowa Carver College of Medicine, Iowa City, Iowa, United States of America
    PLoS ONE 8:e58708. 2013
    ..Thus, ventral striatal activity in anticipation of absolute and relative rewards develops with age. Absolute reward processing is also linked to individual differences in Impulsivity...
  15. ncbi request reprint Structural MR image processing using the BRAINS2 toolbox
    Vincent A Magnotta
    Mental Health Clinical Research Center, The University of Iowa Hospitals and Clinics, Room 2911 JPP, 200 Hawkins Drive, Iowa City, IA 52242, USA
    Comput Med Imaging Graph 26:251-64. 2002
    ..These features are described in detail, as well as the reliability of these procedures...

Research Grants9

  1. ACUTE MARIJUANA EFFECTS ON REGIONAL CEREBRAL BLOOD FLOW
    DANIEL O LEARY; Fiscal Year: 2000
    ..It will also be the first study to provide information about whether the acute changes in rCBF and cognitive function caused by smoking marijuana become more severe following chronic use of this substance. ..
  2. ACUTE MARIJUANA EFFECTS ON REGIONAL CEREBRAL BLOOD FLOW
    DANIEL O LEARY; Fiscal Year: 2007
    ..Finally, cognitive tasks requiring self-paced timing and other putative cerebellar functions will be used to assess the functional consequences of cerebellar hypoperfusion in chronic users of marijuana. ..
  3. Brain Development in Adolescents with Genetic Risk Factors for Alcoholism
    DANIEL S O LEARY; Fiscal Year: 2010
    ....