Michele L Okun

Summary

Affiliation: University of Pittsburgh
Country: USA

Publications

  1. pmc Disturbed sleep is associated with increased C-reactive protein in young women
    Michele L Okun
    University of Pittsburgh, Western Psychiatric Institute and Clinic, 3811 O Hara Street, Room E 1116, Pittsburgh, PA 15213, USA
    Brain Behav Immun 23:351-4. 2009
  2. doi request reprint Disturbed sleep and inflammatory cytokines in depressed and nondepressed pregnant women: an exploratory analysis of pregnancy outcomes
    Michele L Okun
    Sleep Medicine Institute and Department of Psychiatry, School of Medicine, University of Pittsburgh, Pittsburgh, PA, USA
    Psychosom Med 75:670-81. 2013
  3. pmc Disturbed sleep, a novel risk factor for preterm birth?
    Michele L Okun
    Sleep Medicine Institute and Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA
    J Womens Health (Larchmt) 21:54-60. 2012
  4. pmc Changes in sleep quality, but not hormones predict time to postpartum depression recurrence
    Michele L Okun
    University of Pittsburgh School of Medicine, Department of Psychiatry, USA
    J Affect Disord 130:378-84. 2011
  5. pmc Subjective sleep disturbance during a smoking cessation program: associations with relapse
    Michele L Okun
    University of Pittsburgh School of Medicine, Department of Psychiatry, Western Psychiatric Institute and Clinic, 3811 O Hara Street, Pittsburgh, PA 15213, USA
    Addict Behav 36:861-4. 2011
  6. pmc What constitutes too long of a delay? Determining the cortisol awakening response (CAR) using self-report and PSG-assessed wake time
    Michele L Okun
    University of Pittsburgh School of Medicine, Department of Psychiatry, United States
    Psychoneuroendocrinology 35:460-8. 2010
  7. pmc Sleep complaints in late pregnancy and the recurrence of postpartum depression
    Michele L Okun
    Department of Psychiatry, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15213, USA
    Behav Sleep Med 7:106-17. 2009
  8. pmc Sleep disturbances in depressed and nondepressed pregnant women
    Michele L Okun
    Sleep Medicine Institute and Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania
    Depress Anxiety 28:676-85. 2011
  9. pmc How disturbed sleep may be a risk factor for adverse pregnancy outcomes
    Michele L Okun
    University of Pittsburgh, Western Psychiatric Institute and Clinic, PA 15213, USA
    Obstet Gynecol Surv 64:273-80. 2009
  10. pmc Poor sleep quality is associated with preterm birth
    Michele L Okun
    University of Pittsburgh School of Medicine, Department of Psychiatry, Pittsburgh, PA 15213, USA
    Sleep 34:1493-8. 2011

Detail Information

Publications19

  1. pmc Disturbed sleep is associated with increased C-reactive protein in young women
    Michele L Okun
    University of Pittsburgh, Western Psychiatric Institute and Clinic, 3811 O Hara Street, Room E 1116, Pittsburgh, PA 15213, USA
    Brain Behav Immun 23:351-4. 2009
    ..Future work should longitudinally evaluate how these relationships may affect development of gender-specific diseases in apparently healthy young women...
  2. doi request reprint Disturbed sleep and inflammatory cytokines in depressed and nondepressed pregnant women: an exploratory analysis of pregnancy outcomes
    Michele L Okun
    Sleep Medicine Institute and Department of Psychiatry, School of Medicine, University of Pittsburgh, Pittsburgh, PA, USA
    Psychosom Med 75:670-81. 2013
    ....
  3. pmc Disturbed sleep, a novel risk factor for preterm birth?
    Michele L Okun
    Sleep Medicine Institute and Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA
    J Womens Health (Larchmt) 21:54-60. 2012
    ..We evaluated whether sleep disturbance was associated with PTB and whether the association was affected by other psychosocial risk factors...
  4. pmc Changes in sleep quality, but not hormones predict time to postpartum depression recurrence
    Michele L Okun
    University of Pittsburgh School of Medicine, Department of Psychiatry, USA
    J Affect Disord 130:378-84. 2011
    ..We evaluated change over time in sleep quality and hormones during the first 17 weeks postpartum, as well as a single cytokine measure, and their association with PPMD recurrence...
  5. pmc Subjective sleep disturbance during a smoking cessation program: associations with relapse
    Michele L Okun
    University of Pittsburgh School of Medicine, Department of Psychiatry, Western Psychiatric Institute and Clinic, 3811 O Hara Street, Pittsburgh, PA 15213, USA
    Addict Behav 36:861-4. 2011
    ..We describe sleep changes across three months among women in a smoking cessation program and tested whether sleep disturbances at baseline and 1 month post-quit attempt predicted smoking status at three months...
  6. pmc What constitutes too long of a delay? Determining the cortisol awakening response (CAR) using self-report and PSG-assessed wake time
    Michele L Okun
    University of Pittsburgh School of Medicine, Department of Psychiatry, United States
    Psychoneuroendocrinology 35:460-8. 2010
    ..Later collection times and reduced CAR values may affect the interpretation of clinical associations. Our data also show that S-R assessments of wake time perform equally well to PSG for evaluating adherence with CAR sampling procedures...
  7. pmc Sleep complaints in late pregnancy and the recurrence of postpartum depression
    Michele L Okun
    Department of Psychiatry, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15213, USA
    Behav Sleep Med 7:106-17. 2009
    ..9 vs. 7.3 for non-recurrers, p = .02). Sleep quality in late pregnancy may help in identifying women at risk for a PPMD recurrence...
  8. pmc Sleep disturbances in depressed and nondepressed pregnant women
    Michele L Okun
    Sleep Medicine Institute and Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania
    Depress Anxiety 28:676-85. 2011
    ....
  9. pmc How disturbed sleep may be a risk factor for adverse pregnancy outcomes
    Michele L Okun
    University of Pittsburgh, Western Psychiatric Institute and Clinic, PA 15213, USA
    Obstet Gynecol Surv 64:273-80. 2009
    ....
  10. pmc Poor sleep quality is associated with preterm birth
    Michele L Okun
    University of Pittsburgh School of Medicine, Department of Psychiatry, Pittsburgh, PA 15213, USA
    Sleep 34:1493-8. 2011
    ..Poor sleep quality is a correlate of adverse health outcomes. Therefore, we evaluated whether sleep quality during pregnancy was a clinically relevant risk factor for PTB...
  11. pmc Sleep variability, health-related practices, and inflammatory markers in a community dwelling sample of older adults
    Michele L Okun
    Sleep Medicine Institute and Department of Psychiatry, University of Pittsburgh School of Medicine, Western Psychiatric Institute and Clinic, Pittsburgh, PA 15213, USA
    Psychosom Med 73:142-50. 2011
    ..Health behaviors, including average aggregate measures of sleep, have been linked to increased inflammation in older adults. Variability in sleep timing may also be associated with increased inflammation...
  12. pmc Protecting sleep, promoting health in later life: a randomized clinical trial
    Charles F Reynolds
    Sleep and Chronobiology Program, Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA
    Psychosom Med 72:178-86. 2010
    ..5 years; and 2) if maintenance or enhancement of sleep continuity and depth promotes the maintenance or enhancement of health-related quality of life...
  13. pmc Prevalence of sleep deficiency in early gestation and its associations with stress and depressive symptoms
    Michele L Okun
    1 Department of Psychiatry, University of Pittsburgh, Pittsburgh, Pennsylvania
    J Womens Health (Larchmt) 22:1028-37. 2013
    ..We sought to describe the frequency of sleep deficiency across early gestation (10-20 weeks) and whether sleep deficiency is associated with reports of more depressive symptoms and stress...
  14. ncbi request reprint Sleep disturbances increase interleukin-6 production during pregnancy: implications for pregnancy complications
    Michele L Okun
    University of Pittsburgh Medical Center Western Psychiatric Institute and Clinic, Pittsburgh, Pennsylvania, USA
    Reprod Sci 14:560-7. 2007
    ..No relationships were observed for TNF-alpha. These preliminary findings indicate that women who experience sleep disturbances as early as mid gestation are likely to have an increase in inflammation...
  15. pmc Sleep is associated with the metabolic syndrome in a multi-ethnic cohort of midlife women: the SWAN Sleep Study
    Martica H Hall
    University of Pittsburgh, Pittsburgh, PA 15213, USA
    Sleep 35:783-90. 2012
    ..We evaluated associations among subjective and objective measures of sleep and the metabolic syndrome in a multi-ethnic sample of midlife women...
  16. pmc Psychometric evaluation of the Insomnia Symptom Questionnaire: a self-report measure to identify chronic insomnia
    Michele L Okun
    University of Pittsburgh, Department of Psychiatry, Pittsburgh, PA 15213, USA
    J Clin Sleep Med 5:41-51. 2009
    ....
  17. doi request reprint Sleep disturbance and cardiometabolic risk factors in early pregnancy: a preliminary study
    Alyssa Haney
    University of Pittsburgh School of Medicine, Department of Psychiatry, Pittsburgh, PA 15213, USA
    Sleep Med 15:444-50. 2014
    ..Cardiometabolic (CM) risk factors are linked to increased morbidity. Disturbed sleep is associated with CM risk factors in late pregnancy, but little is known about sleep in early pregnancy and CM risk factors...
  18. ncbi request reprint Sleep disruption during pregnancy: how does it influence serum cytokines?
    Michele L Okun
    University of Pittsburgh Medical Center, Pittsburgh, PA, USA
    J Reprod Immunol 73:158-65. 2007
    ..Future exploration of these relationships should include functional assessments of immunity as well as polysomnographically recorded sleep...
  19. ncbi request reprint Occurrence of sleep disorders in the families of narcoleptic patients
    Maurice M Ohayon
    Stanford Sleep Epidemiology, School of Medicine, Stanford University, Palo Alto, CA 94303, USA
    Neurology 67:703-5. 2006
    ..They are also at greater risk for insufficient sleep syndrome (odds ratio [OR] 6.1), nocturnal eating (OR 5.7), and adjustment sleep disorder (OR 3.1)...

Research Grants4

  1. Pregnancy-Related Sleep Disturbances May Increase Pregnancy Complications
    Michele Okun; Fiscal Year: 2007
    ....
  2. Pregnancy-Related Sleep Disturbances May Increase Pregnancy Complications
    Michele L Okun; Fiscal Year: 2010
    ..Descriptive statistics will be used for Aim 1. A nested case-control design will be used to analyze the independent and djmamic effects of sleep and inflammation on the risk of pregnancy complications (Aims 2 and 3). ..