R J O'Keefe
Affiliation: University of Rochester
- Cytokine and matrix metalloproteinase expression in pigmented villonodular synovitis may mediate bone and cartilage destructionR J O'Keefe
Department of Pathology, University of Rochester, NY, USA
Iowa Orthop J 18:26-34. 1998..The role of cytokine secretion and regulation of MMP production in PVNS has not been investigated...
- Runx2-mediated activation of the Bax gene increases osteosarcoma cell sensitivity to apoptosisR A Eliseev
Department of Orthopaedics, Center for Musculoskeletal Research, University of Rochester Medical Center, Rochester, NY, USA
Oncogene 27:3605-14. 2008..Our study provides the first evidence for Bax as a direct target of Runx2, suggesting that Runx2 may act as a proapoptotic factor in osteosarcoma cells...
- Light-activated gene transduction of recombinant adeno-associated virus in human mesenchymal stem cellsH Ito
The Center for Musculoskeletal Research, University of Rochester, Rochester, NY 14642, USA
Gene Ther 11:34-41. 2004..These results demonstrate that LAGT combined with rAAV is a promising procedure to facilitate gene induction in HuMSCs for human gene therapy...
- Cloning of the chick BMP1/Tolloid cDNA and expression in skeletal tissuesS D Reynolds
Department of Pathology and Laboratory Medicine, University of Rochester, School of Medicine and Dentistry, 601 Elmwood Avenue, Box 665, Rochester, NY 14642, USA
Gene 248:233-43. 2000..The Chordin gene is also expressed in chondrocytes and osteoblasts, suggesting that BMP1 and Tolloid influence BMP signaling as well as matrix maturation during skeletogenesis...