R J O'Keefe

Summary

Affiliation: University of Rochester
Country: USA

Publications

  1. pmc Cytokine and matrix metalloproteinase expression in pigmented villonodular synovitis may mediate bone and cartilage destruction
    R J O'Keefe
    Department of Pathology, University of Rochester, NY, USA
    Iowa Orthop J 18:26-34. 1998
  2. doi request reprint Runx2-mediated activation of the Bax gene increases osteosarcoma cell sensitivity to apoptosis
    R A Eliseev
    Department of Orthopaedics, Center for Musculoskeletal Research, University of Rochester Medical Center, Rochester, NY, USA
    Oncogene 27:3605-14. 2008
  3. ncbi request reprint Light-activated gene transduction of recombinant adeno-associated virus in human mesenchymal stem cells
    H Ito
    The Center for Musculoskeletal Research, University of Rochester, Rochester, NY 14642, USA
    Gene Ther 11:34-41. 2004
  4. ncbi request reprint Cloning of the chick BMP1/Tolloid cDNA and expression in skeletal tissues
    S D Reynolds
    Department of Pathology and Laboratory Medicine, University of Rochester, School of Medicine and Dentistry, 601 Elmwood Avenue, Box 665, Rochester, NY 14642, USA
    Gene 248:233-43. 2000

Collaborators

  • E M Schwarz
  • H Ito
  • R A Eliseev
  • R N Rosier
  • S D Reynolds
  • M J Zuscik
  • E Sampson
  • Y F Dong
  • M H Drissi
  • P R Reynolds
  • J E Puzas
  • D Zhang

Detail Information

Publications4

  1. pmc Cytokine and matrix metalloproteinase expression in pigmented villonodular synovitis may mediate bone and cartilage destruction
    R J O'Keefe
    Department of Pathology, University of Rochester, NY, USA
    Iowa Orthop J 18:26-34. 1998
    ..The role of cytokine secretion and regulation of MMP production in PVNS has not been investigated...
  2. doi request reprint Runx2-mediated activation of the Bax gene increases osteosarcoma cell sensitivity to apoptosis
    R A Eliseev
    Department of Orthopaedics, Center for Musculoskeletal Research, University of Rochester Medical Center, Rochester, NY, USA
    Oncogene 27:3605-14. 2008
    ..Our study provides the first evidence for Bax as a direct target of Runx2, suggesting that Runx2 may act as a proapoptotic factor in osteosarcoma cells...
  3. ncbi request reprint Light-activated gene transduction of recombinant adeno-associated virus in human mesenchymal stem cells
    H Ito
    The Center for Musculoskeletal Research, University of Rochester, Rochester, NY 14642, USA
    Gene Ther 11:34-41. 2004
    ..These results demonstrate that LAGT combined with rAAV is a promising procedure to facilitate gene induction in HuMSCs for human gene therapy...
  4. ncbi request reprint Cloning of the chick BMP1/Tolloid cDNA and expression in skeletal tissues
    S D Reynolds
    Department of Pathology and Laboratory Medicine, University of Rochester, School of Medicine and Dentistry, 601 Elmwood Avenue, Box 665, Rochester, NY 14642, USA
    Gene 248:233-43. 2000
    ..The Chordin gene is also expressed in chondrocytes and osteoblasts, suggesting that BMP1 and Tolloid influence BMP signaling as well as matrix maturation during skeletogenesis...