Research Topics
| A O OjoSummaryAffiliation: University of Michigan Country: USA Publications
Research Grants
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Detail Information
Publications
Comparison of the long-term outcomes of kidney transplantation: USA versus SpainAkinlolu O Ojo
Department of Medicine, University of Michigan, Ann Arbor, MI, USA
Nephrol Dial Transplant 28:213-20. 2013..We evaluated the rates of late graft failure and death among US and Spanish kidney recipients...
Prognosis after primary renal transplant failure and the beneficial effects of repeat transplantation: multivariate analyses from the United States Renal Data SystemA Ojo
Department of Medicine, University of Michigan, Ann Arbor, USA
Transplantation 66:1651-9. 1998..Survival of transplant recipients after primary renal allograft failure has not been well studied...- Chronic renal failure after transplantation of a nonrenal organAkinlolu O Ojo
Scientific Registry of Transplant Recipients, Department of Medicine, University of Michigan, Ann Arbor 48109 0364, USA
N Engl J Med 349:931-40. 2003..We conducted a population-based cohort analysis to evaluate the incidence of chronic renal failure, risk factors for it, and the associated hazard of death in recipients of nonrenal transplants... - Expanded criteria donors: process and outcomesAkinlolu O Ojo
Department of Medicine, University of Michigan, Ann Arbor, Michigan 48109 0364, USA
Semin Dial 18:463-8. 2005.... - Quantifying organ donation rates by donation service areaAkinlolu O Ojo
Scientific Registry of Transplant Recipients, University of Michigan, Ann Arbor, MI, USA
Am J Transplant 5:958-66. 2005..g., hospital or OPO). The inherent strengths and weaknesses of metrics such as donors per eligible deaths, donors per notifiable deaths, and number of organs per donor are discussed in detail... - Renal disease in recipients of nonrenal solid organ transplantationAkinlolu O Ojo
Division of Nephrology, University of Michigan Medical School, Ann Arbor, MI 48109, USA
Semin Nephrol 27:498-507. 2007..Compared with maintenance dialysis, kidney transplantation reduces long-term mortality by 60% to 70% in nonrenal transplant recipients with end-stage renal disease... - Organ donation and utilization in the USAAkinlolu O Ojo
Scientific Registry of Transplant Recipients University of Michigan, Ann Arbor, MI, USA
Am J Transplant 4:27-37. 2004..The kidney is the organ most likely to be discarded after recovery. Over the past decade the discard rate of recovered kidneys has increased from 6% to 11%. Many of these are expanded criteria donor kidneys... - Survival in recipients of marginal cadaveric donor kidneys compared with other recipients and wait-listed transplant candidatesA O Ojo
Department of Medicine, University of Michigan, Ann Arbor, Michigan, USA
J Am Soc Nephrol 12:589-97. 2001..It is concluded that transplantation of a marginal kidney is associated with a significant survival benefit when compared with maintenance dialysis... - Dialysis modality and the risk of allograft thrombosis in adult renal transplant recipientsA O Ojo
Department of Medicine, University of Michigan, Veteran Administration Hospital, Ann Arbor, USA
Kidney Int 55:1952-60. 1999..Uremic coagulopathy and dialysis modality may predispose to RVT. We investigated the impact of the pretransplant dialysis modality on the risk of RVT in adult renal transplant recipients... - Long-term survival in renal transplant recipients with graft functionA O Ojo
Departments of Medicine, The University of Michigan, Ann Arbor, Michigan 48109 0364, USA
Kidney Int 57:307-13. 2000..Long-term survival in renal transplant recipients with graft function... - Impact of pre-existing donor hypertension and diabetes mellitus on cadaveric renal transplant outcomesA O Ojo
Departments of Medicine, Surgery, Biostatistics, and Epidemiology, University of Michigan, Ann Arbor, MI 48109 0364, USA
Am J Kidney Dis 36:153-9. 2000.... - Renal transplantation in end-stage sickle cell nephropathyA O Ojo
Department of Medicine, University of Michigan, Ann Arbor, USA
Transplantation 67:291-5. 1999..The role of renal transplantation as treatment for end-stage sickle cell nephropathy (SCN) has not been well established... - Interaction of mycophenolate mofetil and HLA matching on renal allograft survivalH U Meier-Kriesche
Department of Medicine, The University of Michigan, Ann Arbor 48109-0364, USA
Transplantation 71:398-401. 2001..Our study would suggest that HLA matching and MMF therapy are additive factors in decreasing the risk for renal allograft loss... - Gender differences in the risk for chronic renal allograft failureH U Meier-Kriesche
Department of Medicine, University of Michigan, Ann Arbor 48109-0364, USA
Transplantation 71:429-32. 2001..Females have a higher risk of AR while having a decreased risk of graft loss secondary to CAF... - Comparison of mortality in all patients on dialysis, patients on dialysis awaiting transplantation, and recipients of a first cadaveric transplantR A Wolfe
U S Renal Data System Coordinating Center, Department of Biostatistics, University of Michigan, Ann Arbor 48103, USA
N Engl J Med 341:1725-30. 1999.... - Hepatitis C antibody status and outcomes in renal transplant recipientsH U Meier-Kriesche
University of Michigan Health System, Division of Nephrology, 3914 Taubman Center, Ann Arbor, MI 48109, USA
Transplantation 72:241-4. 2001..The current policy of transplanting hepatitis C-positive patients without active liver disease seems to incur no excess mortality risk... - Survival improvement among patients with end-stage renal disease: trends over time for transplant recipients and wait-listed patientsH U Meier-Kriesche
Department of Internal Medicine, University of Michigan, Ann Arbor 48109-0364, USA
J Am Soc Nephrol 12:1293-6. 2001..These favorable trends most likely represent equal advances in transplantation, dialysis, and general medical care... - Influence of recipient race on the outcome of simultaneous pancreas and kidney transplantationF L Luan
Division of Nephrology, Department of Internal Medicine, University of Michigan, Ann Arbor, MI, USA
Am J Transplant 10:2074-81. 2010..42, 95% CI 1.15, 1.75, p = 0.001). In the era of modern immunosuppression, AA SPK transplant patients continue to have inferior graft outcome. Additional studies to explore the mechanisms of such racial disparity are warranted... - Mortality experience in recipients undergoing repeat transplantation with expanded criteria donor and non-ECD deceased-donor kidneysC D Miles
Department of Medicine, University of Michigan, Ann Arbor, MI, USA
Am J Transplant 7:1140-7. 2007..44; p<0.0001). Based on these national data, recipients of ECD retransplantation do not have a survival advantage relative to conventional therapy, whereas non-ECD retransplantation is associated with a significant survival advantage... - Comparative risk of impaired glucose metabolism associated with cyclosporine versus tacrolimus in the late posttransplant periodF L Luan
Internal Medicine, Division of Nephrology, University of Michigan, Ann Arbor, MI, USA
Am J Transplant 8:1871-7. 2008..4% in group I and group II, respectively (p = 0.90). In conclusion, conversion to Tac, compared to continuous exposure to CsA, carries quantitatively similar risk of impaired glucose metabolism in KTRs in the late posttransplant period... - The impact of simultaneous pancreas-kidney transplantation on long-term patient survivalA O Ojo
Department of Medicine, University of Michigan, Ann Arbor 48109-0364, USA
Transplantation 71:82-90. 2001..CONCLUSIONS: Among patients with type 1 DM with end-stage nephropathy, SPK transplantation before the age of 50 years was associated with long-term improvement in survival compared to solitary cadaveric renal transplantation or dialysis... - Choice of induction regimens on the risk of cytomegalovirus infection in donor-positive and recipient-negative kidney transplant recipientsF L Luan
Department of Internal Medicine, Division of Nephrology, University of Michigan, Ann Arbor, Michigan, USA
Transpl Infect Dis 12:473-9. 2010..We investigated the impact of various antibody induction regimens on CMV infection in this group of patients... - Impact of cytomegalovirus disease in D+/R- kidney transplant patients receiving 6 months low-dose valganciclovir prophylaxisF L Luan
Internal Medicine, Division of Nephrology, University of Michigan, Ann Arbor, MI, USA
Am J Transplant 11:1936-42. 2011..15-7.61, p = 0.025). In conclusion, late-onset CMV disease continues to negatively impact kidney transplant outcome despite 6-month low-dose VGCV prophylaxis. Investigations focusing on novel preventive approaches should be emphasized... - Exponentially increased risk of infectious death in older renal transplant recipientsH U Meier-Kriesche
Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, USA
Kidney Int 59:1539-43. 2001..This may have an impact on future immunosuppressive regimens in this population... - Racial disparities in access to simultaneous pancreas-kidney transplantation in the United StatesR B Isaacs
Departments of Medicine, Sociology, and Surgery, University of Virginia, Charlottesville, VA, USA
Am J Kidney Dis 36:526-33. 2000..Our preliminary data support current efforts to encourage Medicare and Medicaid coverage for all patients requiring SPK transplantation regardless of racial or financial status... 
Graft and patient survival in kidney transplant recipients selected for de novo steroid-free maintenance immunosuppressionF L Luan
Internal Medicine, Division of Nephrology, University of Michigan, Ann Arbor, MI, USA
Am J Transplant 9:160-8. 2009..De novo steroid-free immunosuppression as currently practiced in the United States appears to carry no increased risk of adverse clinical outcomes in the intermediate term...- Excess risk of renal allograft loss associated with cigarette smokingR S Sung
Department of Surgery, 2926 Taubman Center, University of Michigan Health System, 1500 East Medical Center Drive, Ann Arbor, MI 48109-0331, USA
Transplantation 71:1752-7. 2001..Smoking cessation before renal transplantation has beneficial effects on graft survival. These effects should be emphasized to patients with end-stage renal disease who are considering renal transplantation... - Immunosuppression and the risk of post-transplant malignancy among cadaveric first kidney transplant recipientsRami T Bustami
Scientific Registry of Transplant Recipients University Renal Research and Education Association, Ann Arbor, MI, USA
Am J Transplant 4:87-93. 2004..024). These new estimates of the magnitude of malignancy risk associated with induction therapy may be useful for clinical practice... - Impact of MELD-based allocation on end-stage renal disease after liver transplantationP Sharma
Department of Internal Medicine, University of Michigan, Ann Arbor, MI, USA
Am J Transplant 11:2372-8. 2011..This study identified potentially modifiable risk factors of post-LT ESRD. Early intervention and modification of these risk factors may reduce the burden of post-LT ESRD... - Database comparison of the adult-to-adult living donor liver transplantation cohort study (A2ALL) and the SRTR U.S. Transplant RegistryB W Gillespie
Department of Biostatistics, University of Michigan, Ann Arbor, USA
Am J Transplant 10:1621-33. 2010..These findings support an expanded focus on data quality control by OPTN/SRTR for a broader variable set than those used for allocation. Center-specific monitoring of missing values could substantially improve the data... - Interaction between donor and recipient age in determining the risk of chronic renal allograft failureHerwig-Ulf Meier-Kriesche
Department of Medicine, The University of Michigan, Ann Arbor, Michigan, USA
J Am Geriatr Soc 50:14-7. 2002..An overall additive and, in the long term (beyond 36 months posttransplant), synergistic deleterious effect on renal allograft survival was observed for the interaction of donor and recipient age... - Abnormal glucose metabolism and metabolic syndrome in non-diabetic kidney transplant recipients early after transplantationFu L Luan
Division of Nephrology, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, USA
Transplantation 89:1034-9. 2010..We prospectively studied the relationship between AGM and MS in non-diabetic kidney transplant recipients early after transplantation... - CKD progression and mortality among older patients with diabetesUptal D Patel
Veterans Affairs Health Services Research and Development Center of Excellence, VA Ann Arbor Healthcare System, Department of Internal Medicine, University of Michigan Health System, Ann Arbor, MI, USA
Am J Kidney Dis 46:406-14. 2005..In addition, little is known about patterns of nephrology care in patients with CKD... - Addition of adult-to-adult living donation to liver transplant programs improves survival but at an increased costPatrick G Northup
Department of Medicine, University of Virginia, Charlottesville, VA, USA
Liver Transpl 15:148-62. 2009..The addition of LDLT to a standard waiting list DDLT program is effective at improving recipient survival and preventing waiting list deaths but at a greater cost... - Deceased-donor characteristics and the survival benefit of kidney transplantationRobert M Merion
Department of Surgery, University of Michigan Health System, Ann Arbor 48109 0331, USA
JAMA 294:2726-33. 2005..However, if ECD transplants offer improved overall patient survival, inferior graft outcome may represent an acceptable trade-off... - Steroid-free maintenance immunosuppression in kidney transplantation: is it time to consider it as a standard therapy?Fu L Luan
Department of Internal Medicine, University of Michigan, Ann Arbor, 48109 0364, USA
Kidney Int 76:825-30. 2009.... - Donor morbidity after living donation for liver transplantationRafik M Ghobrial
Department of Surgery, University of California Los Angeles, Los Angeles, California, USA
Gastroenterology 135:468-76. 2008..The rate and severity of complications in living donors were investigated in the 9-center Adult-to-Adult Living Donor Liver Transplantation Cohort Study (A2ALL)... - Impact of simultaneous pancreas and kidney transplantation on cardiovascular risk factors in patients with type 1 diabetes mellitusFu L Luan
Internal Medicine, Division of Nephrology, University of Michigan, 1500 East Medical Center Drive, Ann Arbor, MI 48109, USA
Transplantation 84:541-4. 2007..We conclude that SPK significantly improves blood pressure and dyslipidemia compared with KTA in type 1 diabetic ESRD patients... - Universal prophylaxis is cost effective in cytomegalovirus serology-positive kidney transplant patientsFu L Luan
Division of Nephrology, Department of Internal Medicine, University of Michigan, Ann Arbor, MI, USA
Transplantation 91:237-44. 2011..We performed cost effectiveness and cost utility modeling comparing these two approaches... - Transition from donor candidates to live kidney donors: the impact of race and undiagnosed medical disease statesSilas P Norman
Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, USA
Clin Transplant 25:136-45. 2011..The prevalence of medical disease in LKD candidates has not been well studied. We examined the medical limitations to living kidney donation in a large Midwestern transplant center... - New-onset diabetes mellitus in kidney transplant recipients discharged on steroid-free immunosuppressionFu L Luan
Division of Nephrology, Department of Internal Medicine, University of Michigan, Ann Arbor, MI 48109 0364, USA
Transplantation 91:334-41. 2011..New-onset diabetes after transplant (NODAT) is a serious complication after kidney transplantation. We studied the relationship between steroid-free maintenance regimens and NODAT in a national cohort of adult kidney transplant patients... - Gender imbalance and outcomes in living donor renal transplantation in the United StatesLiise K Kayler
Department of Surgery, University of Michigan, Ann Arbor, MI, USA
Am J Transplant 3:452-8. 2003..There appears to be a graft survival advantage for male recipients of male donor kidneys... - Evaluation of pancreatic allograft dysfunction by laparoscopic biopsyLiise K Kayler
Department of Surgery, University of Michigan Health System, Ann Arbor, MI 48109, USA
Transplantation 74:1287-9. 2002..CONCLUSIONS: Laparoscopic pancreas transplant biopsy allows safe visualization of the allograft and effective specimen retrieval, and in some cases provides the opportunity for therapeutic intervention... - The Chronic Renal Insufficiency Cohort (CRIC) Study: Design and MethodsHarold I Feldman
Center for Clinical Epidemiology, Philadelphia, 19104, USA
J Am Soc Nephrol 14:S148-53. 2003..Insights from CRIC should lead to the formulation of hypotheses regarding therapy that will serve as the basis for targeted interventional trials focused on reducing the burden of CRI and CVD... - Periodontal disease and other nontraditional risk factors for CKDMonica A Fisher
Case Western Reserve University, Cleveland, OH 44106 4905, USA
Am J Kidney Dis 51:45-52. 2008..Given the systemic inflammatory response to periodontal disease, we hypothesized that periodontal disease could be associated with chronic kidney disease... - Pre-transplant risk factors for chronic renal dysfunction after pediatric heart transplantation: a 10-year national cohort studyCaroline K Lee
Children s Hospital of the King s Daughters, Norfolk, Virginia, USA corrected
J Heart Lung Transplant 26:458-65. 2007..We examined the incidence of end-stage renal disease (ESRD) and chronic renal insufficiency (CRI) after PHTx, the associated pre-transplant patient characteristics, and impact of renal disease on survival... - Organ donation in the United StatesHoward M Nathan
Gift of Life Donor Program, Philadelphia, PA, USA
Am J Transplant 3:29-40. 2003 - Cardiovascular complications after renal transplantation and their preventionAkinlolu O Ojo
Transplantation 82:603-11. 2006..Timely utilization of coronary revascularization procedures should be undertaken as these treatments are equally effective in the kidney transplant population... - Meeting the challenge to improve the treatment of hypertension in blacksAntonio Alberto Lopes
Department of Medicine, Federal University of Bahia, Brazil
J Clin Hypertens (Greenwich) 5:393-401. 2003..Studies to evaluate the effects of the new antihypertensives in improving outcomes in blacks living outside the United States are needed...
Research Grants
- Physician Peer Minority Organ Donation Education ModelAkinlolu Ojo; Fiscal Year: 2006..abstract_text> ..
- Prospective Cohort Study of Chronic Renal InsufficiencyAkinlolu Ojo; Fiscal Year: 2007..The most promising of these hypotheses will require testing in randomized clinical trials. ..
- Prospective Cohort Study of Chronic Renal InsufficiencyAkinlolu Ojo; Fiscal Year: 2007..The most promising of these hypotheses will require testing in randomized clinical trials. ..
- Cardiovascular and Renal Events in Kidney DiseaseAkinlolu Ojo; Fiscal Year: 2006..abstract_text> ..