E Magnus Ohman

Summary

Affiliation: University of North Carolina
Country: USA

Publications

  1. ncbi Tenecteplase and tirofiban in ST-segment elevation acute myocardial infarction: results of a randomized trial
    E Magnus Ohman
    Division of Cardiology, University of North Carolina, UNC Heart Center, Chapel Hill, NC, USA
    Am Heart J 150:79-88. 2005
  2. ncbi Thrombolysis and counterpulsation to improve survival in myocardial infarction complicated by hypotension and suspected cardiogenic shock or heart failure: results of the TACTICS Trial
    E Magnus Ohman
    The University of North Carolina at Chapel Hill, 130 Mason Farm Road, Chapel Hill, NC 27599, USA
    J Thromb Thrombolysis 19:33-9. 2005
  3. ncbi Identification, diagnosis and treatment of heparin-induced thrombocytopenia and thrombosis: a registry of prolonged heparin use and thrombocytopenia among hospitalized patients with and without cardiovascular disease. The Complication After Thrombocytopen
    E Magnus Ohman
    Division of Cardiology, Division of Hematology, and School of Pharmacy, University of North Carolina, Chapel Hill, NC 27599 7075, USA
    J Thromb Thrombolysis 19:11-9. 2005
  4. ncbi Care of non-ST-segment elevation patients: insights from the CRUSADE national quality improvement initiative
    E Magnus Ohman
    Division of Cardiology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA
    Am Heart J 148:S34-9. 2004
  5. ncbi An analysis of the Association of Society of Chest Pain Centers Accreditation to American College of Cardiology/American Heart Association non-ST-segment elevation myocardial infarction guideline adherence
    Abhinav Chandra
    Duke University Medical Center, Durham, NC, USA
    Ann Emerg Med 54:17-25. 2009
  6. ncbi Impact of acute beta-blocker therapy for patients with non-ST-segment elevation myocardial infarction
    Chadwick D Miller
    Wake Forest University Health Sciences, Winston Salem, NC, USA
    Am J Med 120:685-92. 2007
  7. ncbi Hypercholesterolemia paradox in relation to mortality in acute coronary syndrome
    Tracy Y Wang
    Division of Cardiology, Duke Clinical Research Institute, Duke University Medical Center, Durham, North Carolina 27705, USA
    Clin Cardiol 32:E22-8. 2009
  8. ncbi Clinical characteristics, process of care, and outcomes of Hispanic patients presenting with non-ST-segment elevation acute coronary syndromes: results from Can Rapid risk stratification of Unstable angina patients Suppress ADverse outcomes with Early imp
    Mauricio G Cohen
    Division of Cardiology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599 7075, USA
    Am Heart J 152:110-7. 2006
  9. ncbi Timing of in-hospital coronary artery bypass graft surgery for non-ST-segment elevation myocardial infarction patients results from the National Cardiovascular Data Registry ACTION Registry-GWTG (Acute Coronary Treatment and Intervention Outcomes Network
    Shailja V Parikh
    Department of Internal Medicine, Division of Cardiology, University of Texas Southwestern Medical Center, Dallas, Texas 75235, USA
    JACC Cardiovasc Interv 3:419-27. 2010
  10. ncbi Polyvascular disease and long-term cardiovascular outcomes in older patients with non-ST-segment-elevation myocardial infarction
    Sumeet Subherwal
    Duke University Medical Center, Durham, NC, USA
    Circ Cardiovasc Qual Outcomes 5:541-9. 2012

Collaborators

Detail Information

Publications102 found, 100 shown here

  1. ncbi Tenecteplase and tirofiban in ST-segment elevation acute myocardial infarction: results of a randomized trial
    E Magnus Ohman
    Division of Cardiology, University of North Carolina, UNC Heart Center, Chapel Hill, NC, USA
    Am Heart J 150:79-88. 2005
    ..We performed a multicenter dose-ranging study of reduced doses of a newer fibrinolytic (tenecteplase) combined with tirofiban, a glycoprotein IIb/IIIa inhibitor...
  2. ncbi Thrombolysis and counterpulsation to improve survival in myocardial infarction complicated by hypotension and suspected cardiogenic shock or heart failure: results of the TACTICS Trial
    E Magnus Ohman
    The University of North Carolina at Chapel Hill, 130 Mason Farm Road, Chapel Hill, NC 27599, USA
    J Thromb Thrombolysis 19:33-9. 2005
    ..We assessed the benefit of adding 48 hours of intra-aortic balloon counterpulsation (IABP) to standard treatment for MI, in an international trial among hospitals without primary angioplasty capabilities...
  3. ncbi Identification, diagnosis and treatment of heparin-induced thrombocytopenia and thrombosis: a registry of prolonged heparin use and thrombocytopenia among hospitalized patients with and without cardiovascular disease. The Complication After Thrombocytopen
    E Magnus Ohman
    Division of Cardiology, Division of Hematology, and School of Pharmacy, University of North Carolina, Chapel Hill, NC 27599 7075, USA
    J Thromb Thrombolysis 19:11-9. 2005
    ..IMPLICATIONS: The registry will provide valuable insights to the incidence and consequences of HIT and HITT that will enable improvements in diagnosis and treatment...
  4. ncbi Care of non-ST-segment elevation patients: insights from the CRUSADE national quality improvement initiative
    E Magnus Ohman
    Division of Cardiology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA
    Am Heart J 148:S34-9. 2004
    ..These ACC/AHA guidelines are intended to help physicians make appropriate decisions when diagnosing and treating patients with NSTE ACS...
  5. ncbi An analysis of the Association of Society of Chest Pain Centers Accreditation to American College of Cardiology/American Heart Association non-ST-segment elevation myocardial infarction guideline adherence
    Abhinav Chandra
    Duke University Medical Center, Durham, NC, USA
    Ann Emerg Med 54:17-25. 2009
    ..The secondary objective is to describe the clinical outcomes and the association with accreditation...
  6. ncbi Impact of acute beta-blocker therapy for patients with non-ST-segment elevation myocardial infarction
    Chadwick D Miller
    Wake Forest University Health Sciences, Winston Salem, NC, USA
    Am J Med 120:685-92. 2007
    ..We sought to determine the impact of acute beta-blocker therapy on outcomes in patients with NSTEMI...
  7. ncbi Hypercholesterolemia paradox in relation to mortality in acute coronary syndrome
    Tracy Y Wang
    Division of Cardiology, Duke Clinical Research Institute, Duke University Medical Center, Durham, North Carolina 27705, USA
    Clin Cardiol 32:E22-8. 2009
    ..Hypercholesterolemia is a risk factor for coronary artery disease, yet is associated with lower risk of adverse outcomes in patients with acute coronary syndromes (ACS)...
  8. ncbi Clinical characteristics, process of care, and outcomes of Hispanic patients presenting with non-ST-segment elevation acute coronary syndromes: results from Can Rapid risk stratification of Unstable angina patients Suppress ADverse outcomes with Early imp
    Mauricio G Cohen
    Division of Cardiology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599 7075, USA
    Am Heart J 152:110-7. 2006
    ..Data regarding the management of non-ST-segment elevation acute coronary syndromes (NSTE ACS) in Hispanic patients, the largest and fastest-growing minority in the United States, are scarce...
  9. ncbi Timing of in-hospital coronary artery bypass graft surgery for non-ST-segment elevation myocardial infarction patients results from the National Cardiovascular Data Registry ACTION Registry-GWTG (Acute Coronary Treatment and Intervention Outcomes Network
    Shailja V Parikh
    Department of Internal Medicine, Division of Cardiology, University of Texas Southwestern Medical Center, Dallas, Texas 75235, USA
    JACC Cardiovasc Interv 3:419-27. 2010
    ..The aim of this study was to examine timing of in-hospital coronary artery bypass graft surgery (CABG) for non-ST-segment elevation myocardial infarction (NSTEMI) patients...
  10. ncbi Polyvascular disease and long-term cardiovascular outcomes in older patients with non-ST-segment-elevation myocardial infarction
    Sumeet Subherwal
    Duke University Medical Center, Durham, NC, USA
    Circ Cardiovasc Qual Outcomes 5:541-9. 2012
    ..The impact of polyvascular disease (peripheral arterial disease [PAD] and cerebrovascular disease [CVD]) on long-term cardiovascular outcomes among older patients with acute myocardial infarction has not been well studied...
  11. ncbi Incidence, predictors, and outcomes of high-degree atrioventricular block complicating acute myocardial infarction treated with thrombolytic therapy
    Trip J Meine
    Division of Cardiology, Department of Medicine, Duke University, Durham, NC 27715, USA
    Am Heart J 149:670-4. 2005
    ..We sought to delineate predictors of AVB and determine long-term mortality of patients developing AVB in the setting of ST-segment elevation MI (STEMI) treated with thrombolytic therapy...
  12. ncbi Patient satisfaction and its relationship with clinical quality and inpatient mortality in acute myocardial infarction
    Seth W Glickman
    Center for Clinical and Genetic Economics, Duke University, Durham, NC, USA
    Circ Cardiovasc Qual Outcomes 3:188-95. 2010
    ..The objective of this study was to determine whether patient satisfaction is associated with adherence to practice guidelines and outcomes for acute myocardial infarction and to identify the key drivers of patient satisfaction...
  13. ncbi Antiarrhythmic drug therapy for sustained ventricular arrhythmias complicating acute myocardial infarction
    Jonathan P Piccini
    Duke Clinical Research Institute, Duke University Medical Center, Durham, NC, USA
    Crit Care Med 39:78-83. 2011
    ..The objective of this analysis was to describe the survival of patients with sustained ventricular tachycardia/ventricular fibrillation after myocardial infarction according to antiarrhythmic drug treatment...
  14. ncbi Timing of glycoprotein IIb/IIIa inhibitor use and outcomes among patients with non-ST-segment elevation myocardial infarction undergoing percutaneous coronary intervention (results from CRUSADE)
    Pierluigi Tricoci
    Division of Cardiology, and Duke Clinical Research Institute, Duke University Medical Center, Durham, NC, USA
    Am J Cardiol 99:1389-93. 2007
    ..In conclusion, in this observational analysis, overall ischemic outcomes were similar between the 2 groups, but clinical trials are needed to solve the controversy over optional timing of GP IIb/IIIa inhibitor use...
  15. ncbi What aspects of hospital culture influence quality?
    Barbara L Lytle
    Division of Cardiology, Duke Clinical Research Institute, Duke University Medical Center, Durham, North Carolina 27705, USA
    Crit Pathw Cardiol 6:145-9. 2007
  16. ncbi Implications and reasons for the lack of use of reperfusion therapy in patients with ST-segment elevation myocardial infarction: findings from the CRUSADE initiative
    Shahyar Michael Gharacholou
    Duke Clinical Research Institute, Durham, NC, USA
    Am Heart J 159:757-63. 2010
    ..However, many STEMI patients in contemporary practice still do not receive any form of reperfusion therapy...
  17. ncbi Differences in the clinical features and outcomes in African Americans and whites with myocardial infarction
    Rajendra H Mehta
    Duke Clinical Research Institute, Durham, NC, USA
    Am J Med 119:70.e1-8. 2006
    ..Accordingly, the current study examines the relationship of African American race to patient-related clinical factors, angiographic findings, and clinical events...
  18. ncbi Influence of transfer-in rates on quality of care and outcomes at receiving hospitals in patients with non-ST-segment elevation myocardial infarction
    Rajendra H Mehta
    Duke Clinical Research Institute, Duke University Medical Center, Durham, NC, USA
    Am Heart J 160:405-11. 2010
    ....
  19. ncbi Medical records and quality of care in acute coronary syndromes: results from CRUSADE
    Shannon M Dunlay
    Department of Medicine, Duke University Medical Center, Durham, NC, USA
    Arch Intern Med 168:1692-8. 2008
    ..Patient medical records are important means of communication among health care providers. Limited evaluation has been performed of the quality of the medical records or its association with health care processes or outcomes...
  20. ncbi Clinical and research issues regarding chronic advanced coronary artery disease part II: Trial design, outcomes, and regulatory issues
    E Marc Jolicoeur
    Duke University, Durham, NC, USA
    Am Heart J 155:435-44. 2008
    ..The present part reviews the current status of understanding of advanced CAD, the limits of contemporary therapies, and the difficulties in and barriers to the development of new treatments...
  21. ncbi Predicting long-term mortality in older patients after non-ST-segment elevation myocardial infarction: the CRUSADE long-term mortality model and risk score
    Matthew T Roe
    Duke Clinical Research Institute, Durham, NC, USA
    Am Heart J 162:875-883.e1. 2011
    ..We sought to develop a long-term mortality risk prediction model and a simplified risk score for use in older patients with non-ST-segment elevation myocardial infarction (NSTEMI)...
  22. ncbi A framework for quality improvement: an analysis of factors responsible for improvement at hospitals participating in the Can Rapid Risk Stratification of Unstable Angina Patients Suppress Adverse Outcomes with Early Implementation of the ACC/AHA Guidelin
    Seth W Glickman
    Center for Clinical and Genetic Economics, Duke University Medical Center, Durham, NC, USA
    Am Heart J 154:1206-20. 2007
    ....
  23. ncbi Thrombolysis and adjunctive therapy in acute myocardial infarction: the Seventh ACCP Conference on Antithrombotic and Thrombolytic Therapy
    Venu Menon
    Division of Cardiology, University of North Carolina at Chapel Hill, 27599, USA
    Chest 126:549S-575S. 2004
    ....
  24. ncbi Safety and efficacy of bivalirudin monotherapy in patients with diabetes mellitus and acute coronary syndromes: a report from the ACUITY (Acute Catheterization and Urgent Intervention Triage Strategy) trial
    Frederick Feit
    Division of Cardiology, Department of Medicine, New York University School of Medicine, New York, New York, USA
    J Am Coll Cardiol 51:1645-52. 2008
    ..We sought to evaluate clinical outcomes of patients with diabetes mellitus in the ACUITY (Acute Catheterization and Urgent Intervention Triage Strategy) trial, overall and by treatment arm...
  25. ncbi Study design and rationale of a comparison of prasugrel and clopidogrel in medically managed patients with unstable angina/non-ST-segment elevation myocardial infarction: the TaRgeted platelet Inhibition to cLarify the Optimal strateGy to medicallY manage
    Chee Tang Chin
    Duke Clinical Research Institute, Durham, NC, USA
    Am Heart J 160:16-22.e1. 2010
    ....
  26. ncbi Pay for performance, quality of care, and outcomes in acute myocardial infarction
    Seth W Glickman
    Center for Clinical and Genetic Economics, Duke University Medical Center, Durham, NC, USA
    JAMA 297:2373-80. 2007
    ..In 2003, the Centers for Medicare & Medicaid Services (CMS) launched the largest pay-for-performance pilot project to date in the United States, including indicators for acute myocardial infarction...
  27. ncbi Intra-aortic balloon counterpulsation in US and non-US centres: results of the Benchmark Registry
    Marc Cohen
    Division of Cardiology, MCP Hahnemann University School of Medicine, PA, Philadelphia, USA
    Eur Heart J 24:1763-70. 2003
    ..To examine differences in patient characteristics and outcomes in 19636 patients enrolled in the USA and 3027 patients enrolled in other countries undergoing intra-aortic balloon pump (IABP) counterpulsation...
  28. ncbi Hospital performance and differences by kidney function in the use of recommended therapies after non-ST-elevation acute coronary syndromes
    Uptal D Patel
    Division of Nephrology, Duke University Medical Center, Durham, NC, USA
    Am J Kidney Dis 53:426-37. 2009
    ..The extent to which hospital performance affects the care of patients with CKD and non-ST-segment elevation acute coronary syndromes (NSTE ACSs) is unknown...
  29. ncbi Modifiable risk factors control and its relationship with 1 year outcomes after coronary artery bypass surgery: insights from the REACH registry
    Rajendra H Mehta
    Duke Clinical Research Institute, 2400 Pratt Street, PO Box 17969, Durham, NC, USA
    Eur Heart J 29:3052-60. 2008
    ..To evaluate the influence of achieving secondary prevention target treatment goals for cardiovascular (CV) risk factors on clinical outcomes in patients with prior coronary artery bypass surgery (CABG)...
  30. ncbi Temporal changes in the use of drug-eluting stents for patients with non-ST-Segment-elevation myocardial infarction undergoing percutaneous coronary intervention from 2006 to 2008: results from the can rapid risk stratification of unstable angina patients
    Matthew T Roe
    Duke Clinical Research Institute, Duke University Medical Center, Durham, NC, USA
    Circ Cardiovasc Qual Outcomes 2:414-20. 2009
    ..We evaluated trends in the use of DES for patients with non-ST-elevation myocardial infarction undergoing percutaneous coronary intervention (PCI) from 2006 to 2008...
  31. ncbi Clopidogrel to treat patients with non-ST-segment elevation acute coronary syndromes after hospital discharge
    Pierluigi Tricoci
    Division of Cardiology, Duke University School of Medicine, and Duke Clinical Research Institute, Durham, NC, USA
    Arch Intern Med 166:806-11. 2006
    ....
  32. ncbi The impact of emergency department structure and care processes in delivering care for non-ST-segment elevation acute coronary syndromes
    Rajendra H Mehta
    Duke Clinical Research Institute, Duke University Medical Center, Durham, NC, USA
    Am Heart J 152:648-60. 2006
    ..We sought to assess the influence of emergency department (ED) structure and care processes on adherence to practice guidelines for the treatment of patients with non-ST-segment elevation acute coronary syndromes...
  33. ncbi Effects of unfractionated heparin and glycoprotein IIb/IIIa antagonists versus bivalirdin on myeloperoxidase release from neutrophils
    Guohong Li
    Carolina Cardiovascular Biology Center, The University of North Carolina, Chapel Hill, USA
    Arterioscler Thromb Vasc Biol 27:1850-6. 2007
    ..CONCLUSIONS: Adjuvant therapy during PCI may have undesired effects on neutrophil activation, MPO release, and systemic inflammation...
  34. ncbi Regional patterns of use of a medical management strategy for patients with non-ST-segment elevation acute coronary syndromes: insights from the EARLY ACS Trial
    Matthew T Roe
    Duke Clinical Research Institute, Durham, NC, USA
    Circ Cardiovasc Qual Outcomes 5:205-13. 2012
    ..Regional differences in the profile and prognosis of non-ST-segment elevation acute coronary syndrome (NSTE ACS) patients treated with medical management after angiography remain uncertain...
  35. ncbi Obesity and age of first non-ST-segment elevation myocardial infarction
    Mohan C Madala
    Department of Medicine, Division of Cardiology, William Beaumont Hospital, Royal Oak, Michigan 48073, USA
    J Am Coll Cardiol 52:979-85. 2008
    ..Because excess adiposity is one of the most important determinants of adipokines and inflammatory factors associated with coronary plaque rupture, we hypothesized that obesity was associated with myocardial infarction at earlier ages...
  36. ncbi Biomarkers in cardiovascular clinical trials: past, present, future
    Sharif A Halim
    Division of Cardiology, Duke University Medical Center and the Duke Clinical Research Institute, Durham, NC 27710, USA
    Clin Chem 58:45-53. 2012
    ....
  37. ncbi Relation between hospital intra-aortic balloon counterpulsation volume and mortality in acute myocardial infarction complicated by cardiogenic shock
    Edmond W Chen
    Division of Cardiology, Kaiser Permanente Medical Group, Inc, Richmond, CA 94801-3195, USA
    Circulation 108:951-7. 2003
    ..CONCLUSIONS: Among the myocardial infarction patients with cardiogenic shock who underwent IABP placement, mortality rate was significantly lower at high-IABP volume hospitals compared with low-IABP volume hospitals...
  38. ncbi Predicting outcome after thrombolysis in acute myocardial infarction according to ST-segment resolution at 90 minutes: a substudy of the GUSTO-III trial. Global Use of Strategies To Open occluded coronary arteries
    R David Anderson
    Duke Clinical Research Institute, Durham, NC, USA
    Am Heart J 144:81-8. 2002
    ..Whether prognostically useful information can be achieved as early as 90 minutes after thrombolysis is unknown...
  39. ncbi Pulmonary artery catheterization in acute coronary syndromes: insights from the GUSTO IIb and GUSTO III trials
    Mauricio G Cohen
    Division of Cardiology, University of North Carolina at Chapel Hill, 130 Mason Farm Road, CB 7075, Bioinformatics Building Suite 4128, Chapel Hill, NC 27599, USA
    Am J Med 118:482-8. 2005
    ..To correlate pulmonary artery catheterization (PAC) use and 30-day outcomes and to characterize the use of pulmonary artery catheters among patients with acute coronary syndromes (ACS)...
  40. ncbi Aortic counterpulsation: a review of the hemodynamic effects and indications for use
    Richard A Santa-Cruz
    Division of Cardiology, University of North Carolina, Chapel Hill, 27599 7075, USA
    Catheter Cardiovasc Interv 67:68-77. 2006
    ..This article will review the hemodynamics, indications, and complications associated with its use...
  41. ncbi Bivalirudin: a review of the pharmacology and clinical application
    David A Van De Car
    Duke University Medical Center, Division of Cardiology, 2301 Erwin Road, Durham, NC, USA
    Expert Rev Cardiovasc Ther 8:1673-81. 2010
    ..Additional agents in the class of direct thrombin inhibitors are under investigation and may find increasing clinical use...
  42. ncbi Contemporary approach to the diagnosis and management of non-ST-segment elevation acute coronary syndromes
    William E Boden
    Division of Cardiology, Department of Medicine, Buffalo General Hospital and Kaleida Health, State University of New York SUNY at Buffalo School of Medicine and Biomedical Science, Buffalo, NY 14203, USA
    Prog Cardiovasc Dis 50:311-51. 2008
    ....
  43. ncbi Facilitated percutaneous coronary intervention in acute myocardial infarction: attractive concept but difficult to prove!
    Robert V Kelly
    Division of Cardiology, The University of North Carolina at Chapel Hill, Cardiac Catheterization Laboratory, Chapel Hill, NC 27517, USA
    Am Heart Hosp J 2:211-22. 2004
    ..Ongoing trials are evaluating different combinations of thrombolytic and glycoprotein IIb/IIIa inhibitor therapy...
  44. ncbi Implications of elevated cardiac troponin T in ambulatory patients with heart failure: a prospective analysis
    Michael P Hudson
    Duke Clinical Research Institute, Durham, NC, USA
    Am Heart J 147:546-52. 2004
    ..We assessed whether elevated TnT levels are associated with the severity, etiology, and prognosis of HF in stable, ambulatory patients...
  45. ncbi Intra-aortic balloon counterpulsation and infarct size in patients with acute anterior myocardial infarction without shock: the CRISP AMI randomized trial
    Manesh R Patel
    Division of Cardiology, Department of Medicine, Duke Clinical Research Institute, Duke University Medical Center, Durham, North Carolina 27715, USA
    JAMA 306:1329-37. 2011
    ..Intra-aortic balloon counterpulsation (IABC) is an adjunct to revascularization in patients with cardiogenic shock and reduces infarct size when placed prior to reperfusion in animal models...
  46. ncbi Aortic arch atheroma progression and recurrent vascular events in patients with stroke or transient ischemic attack
    Souvik Sen
    Department of Neurology, University of North Carolina, Chapel Hill, USA
    Circulation 116:928-35. 2007
    ..It is not known whether progression of aortic arch (AA) atheroma is associated with vascular events in patients with stroke or transient ischemic attack (TIA)...
  47. ncbi Effect of multielement intravascular ultrasound on the anticoagulant potency of enoxaparin
    George A Stouffer
    Division of Cardiology, Department of Medicine, University of North Carolina, Chapel Hill, NC 27599 7075, USA
    Am J Cardiol 93:1453-4, A12. 2004
    ..This effect occurred rapidly and repeatedly after activation of the IVUS catheter...
  48. ncbi Prevalence of symptomatic diastolic heart failure in patients hospitalized with cerebral or peripheral vascular disease
    Robert V Kelly
    Division of Cardiology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27517, USA
    Congest Heart Fail 11:256-61. 2005
    ..In contrast, symptomatic DHF is found in three times as many age-matched control heart failure patients without clinical vascular disease...
  49. ncbi Clinical and research issues regarding chronic advanced coronary artery disease: part I: Contemporary and emerging therapies
    E Marc Jolicoeur
    Duke University, Durham, NC, USA
    Am Heart J 155:418-34. 2008
    ..Trial design, end points, and regulatory issues will be discussed in the second part of the article...
  50. ncbi The REduction of Atherothrombosis for Continued Health (REACH) Registry: an international, prospective, observational investigation in subjects at risk for atherothrombotic events-study design
    E Magnus Ohman
    Division of Cardiology, Duke University Medical Center, Durham, NC, USA
    Am Heart J 151:786.e1-10. 2006
    ....
  51. ncbi Comparison of outcomes after 8 vs. 9.5 French size intra-aortic balloon counterpulsation catheters based on 9,332 patients in the prospective Benchmark registry
    Marc Cohen
    Division of Cardiology, M C P Hahnemann University, Philadelphia, Pennsylvania, USA
    Catheter Cardiovasc Interv 56:200-6. 2002
    ..The large, population-based, ongoing Benchmark registry provides a useful vehicle for outcomes research concerning the evolving practice of IABC...
  52. ncbi Percutaneous coronary intervention in a patient with immune thrombocytopenia purpura
    George A Stouffer
    C V Richardson Cardiac Catheterization Laboratory, Division of Cardiology, Department of Medicine, University of North Carolina, Chapel Hill, North Carolina 27599, USA
    Catheter Cardiovasc Interv 61:364-7. 2004
    ..Percutaneous revascularization in patients with ITP remains a challenge and this therapeutic approach, while ultimately successful in the patient, requires further validation...
  53. ncbi Amplatzer vascular plug closure of a subclavian arteriovenous fistula associated with implantable cardioverter-defibrillator implantation
    Connie Ng Hess
    Department of Medicine, Division of Cardiology, Duke University Medical Center, Durham, North Carolina, USA
    Catheter Cardiovasc Interv 77:761-3. 2011
    ..The Amplatzer vascular plug should be considered as a potential treatment strategy for AVFs alongside other endovascular and surgical techniques...
  54. ncbi Patterns of transfer for patients with non-ST-segment elevation acute coronary syndrome from community to tertiary care hospitals
    Matthew T Roe
    Duke Clinical Research Institute, Durham, NC 27705, USA
    Am Heart J 156:185-92. 2008
    ....
  55. ncbi Use of and inhospital outcomes after early clopidogrel therapy in patients not undergoing an early invasive strategy for treatment of non-ST-segment elevation myocardial infarction: results from Can Rapid risk stratification of Unstable angina patients Su
    Deepu Alexander
    Division of Cardiovascular Medicine, State University of New York, Stony Brook School of Medicine, Stony Brook, NY 11794, USA
    Am Heart J 156:606-12. 2008
    ..We sought to determine patterns of early (<24 hours of arrival) clopidogrel use and its association with clinical outcomes in patients with NSTEMI not undergoing early percutaneous intervention (PCI)...
  56. ncbi Guidelines for the diagnosis and treatment of non-ST-segment elevation acute coronary syndromes
    Jean-Pierre Bassand
    Eur Heart J 28:1598-660. 2007
  57. ncbi Risk factor profile and management of cerebrovascular patients in the REACH Registry
    Joachim Rother
    Department of Neurology, Klinikum Minden, Hannover Medical School, Minden, Germany
    Cerebrovasc Dis 25:366-74. 2008
    ..We assessed these factors in 18,992 CVD patients within a worldwide registry of stable outpatients...
  58. ncbi Eptifibatide and low-dose tissue plasminogen activator in acute myocardial infarction: the integrilin and low-dose thrombolysis in acute myocardial infarction (INTRO AMI) trial
    Sorin J Brener
    Cleveland Clinic Foundation, Cleveland, Ohio, USA
    J Am Coll Cardiol 39:377-86. 2002
    ..This study was designed to test the hypothesis that eptifibatide and reduced-dose tissue plasminogen activator (t-PA) will enhance infarct artery patency at 60 min in patients with acute myocardial infarction (AMI)...
  59. ncbi Antithrombotic strategies in patients with acute coronary syndromes undergoing early invasive management: one-year results from the ACUITY trial
    Gregg W Stone
    Columbia University Medical Center and the Cardiovascular Research Foundation, New York, New York 10022, USA
    JAMA 298:2497-506. 2007
    ....
  60. ncbi Percutaneous coronary interventions in patients with heparin-induced thrombocytopenia
    E Marc Jolicoeur
    Duke Clinical Research Institute, Duke University Medical Center, Durham, NC 27710, USA
    Curr Cardiol Rep 9:396-405. 2007
    ..The algorithm also integrates preventive measures directed at decreasing the bleeding risk associated with the antithrombotic and invasive therapies used for HIT and percutaneous coronary intervention...
  61. ncbi The Harmonizing Outcomes with RevasculariZatiON and Stents in Acute Myocardial Infarction (HORIZONS-AMI) Trial: study design and rationale
    Roxana Mehran
    Columbia University Medical Center and the Cardiovascular Research Foundation, New York, NY 10032, USA
    Am Heart J 156:44-56. 2008
    ..Newer pharmacologic agents and drug-eluting stents may address both of these issues...
  62. ncbi Paradoxical use of invasive cardiac procedures for patients with non-ST segment elevation myocardial infarction: an international perspective from the CRUSADE Initiative and the Canadian ACS Registries I and II
    Mohammad I Zia
    Canadian Heart Research Centre, Toronto, Canada
    Can J Cardiol 23:1073-9. 2007
    ..Practice guidelines support an early invasive strategy in patients with non-ST segment elevation acute coronary syndromes, particularly in those at higher risk...
  63. ncbi Preliminary experience with intravenous P2Y12 platelet receptor inhibition as an adjunct to reduced-dose alteplase during acute myocardial infarction: results of the Safety, Tolerability and Effect on Patency in Acute Myocardial Infarction (STEP-AMI) angi
    Adam B Greenbaum
    Henry Ford Heart and Vascular Institute, Detroit, MI, USA
    Am Heart J 154:702-9. 2007
    ..The aim of this study was to assess the safety and coronary artery patency of cangrelor as an adjunct to alteplase (tissue plasminogen activator [t-PA])...
  64. ncbi Patterns of aspirin dosing in non-ST-elevation acute coronary syndromes in the CRUSADE Quality Improvement Initiative
    Sumit Tickoo
    Bridgeport Hospital, Bridgeport, Connecticut, USA
    Am J Cardiol 99:1496-9. 2007
    ....
  65. ncbi Acute coronary care in the elderly, part II: ST-segment-elevation myocardial infarction: a scientific statement for healthcare professionals from the American Heart Association Council on Clinical Cardiology: in collaboration with the Society of Geriatric
    Karen P Alexander
    Duke University Medical Center, USA
    Circulation 115:2570-89. 2007
    ....
  66. ncbi Gender disparities in the diagnosis and treatment of non-ST-segment elevation acute coronary syndromes: large-scale observations from the CRUSADE (Can Rapid Risk Stratification of Unstable Angina Patients Suppress Adverse Outcomes With Early Implementatio
    Andra L Blomkalns
    Department of Emergency Medicine, University of Cincinnati College of Medicine, Cincinnati, Ohio 45267 0769, USA
    J Am Coll Cardiol 45:832-7. 2005
    ..We hypothesized that significant disparities in gender exist in the management of patients with non-ST-segment elevation (NSTE) acute coronary syndromes (ACS)...
  67. ncbi Lipid management in patients with unstable angina pectoris and non-ST-segment elevation acute myocardial infarction (from CRUSADE)
    JoAnne M Foody
    Section of Cardiovascular Medicine, Department of Medicine, Yale School of Medicine, New Haven, Connecticut, USA
    Am J Cardiol 95:483-5. 2005
    ....
  68. ncbi Overcoming the challenges facing quality-improvement strategies for non-ST-segment elevation acute coronary syndromes
    Matthew T Roe
    Am Fam Physician 70:1868, 1874, 1876. 2004
  69. ncbi Prognostic value of predischarge electrocardiographic measurement of infarct size after thrombolysis: insights from GUSTO I Economics and Quality of Life substudy
    Alejandro Barbagelata
    Hospital Italiano, Buenos Aires, Argentina
    Am Heart J 148:795-802. 2004
    ..The standard 12-lead ECG provides a simple, economical means of risk stratification at discharge...
  70. ncbi Antithrombotic therapy during percutaneous coronary intervention: the Seventh ACCP Conference on Antithrombotic and Thrombolytic Therapy
    Jeffrey J Popma
    Interventional Cardiology, Brigham and Women s Hospital, 75 Francis St, Tower 2 3A Room 311, Boston, MA 02115, USA
    Chest 126:576S-599S. 2004
    ..In patients who undergo PCI with no other indication for systemic anticoagulation therapy, we recommend against routine use of vitamin K antagonists after PCI (Grade 1A)...
  71. ncbi In-hospital mortality associated with the use of intra-aortic balloon counterpulsation
    Philip M Urban
    La Tour Hospital, Geneva, Switzerland
    Am J Cardiol 94:181-5. 2004
    ..Therefore, diagnostic evaluation and treatment decisions should be made as early as possible, and physicians should be aware of associated risk factors in making choices for patients...
  72. ncbi Bleeding events with abciximab in acute coronary syndromes without early revascularization: An analysis of GUSTO IV-ACS
    Timo Lenderink
    Department of Cardiology, Thoraxcentre, Erasmus Medical Centre, Rotterdam, The Netherlands
    Am Heart J 147:865-73. 2004
    ..Specific dosing guidelines for combination with low-molecular weight heparin must be developed for patients who subsequently will undergo a PCI...
  73. ncbi A randomized, placebo-controlled trial of early eptifibatide for non-ST-segment elevation acute coronary syndromes
    Matthew T Roe
    Duke Clinical Research Institute, Durham, NC 27715, USA
    Am Heart J 146:993-8. 2003
    ..The acute benefits of platelet glycoprotein IIb/IIIa inhibitors for non-ST-segment elevation acute coronary syndromes (NSTE ACS) remain unclear...
  74. ncbi Prognostic importance of new small Q waves following non-ST-elevation acute coronary syndromes
    John H Alexander
    Duke Clinical Research Institute, Durham, North Carolina 27710, USA
    Am J Med 115:613-9. 2003
    ..To investigate the prognostic importance of new small Q waves following an acute coronary syndrome...
  75. ncbi Changing the model of care for patients with acute coronary syndromes
    Matthew T Roe
    Duke Clinical Research Institute, Durham, NC 27715, USA
    Am Heart J 146:605-12. 2003
    ..The shifting model of care for ACS therefore suggests that quality improvement and monitoring of adherence to practice guidelines should be considered components of optimal clinical practice...
  76. ncbi Frequency of stent thrombosis after acute coronary syndromes (from the SYMPHONY and 2nd SYMPHONY trials)
    Thaddeus R Tolleson
    Duke Clinical Research Institute, Durham, North Carolina, USA
    Am J Cardiol 92:330-3. 2003
    ..These patients and their outcomes may be more representative of patients with typical acute coronary syndromes undergoing stenting in clinical practice...
  77. ncbi Sustained ventricular arrhythmias and mortality among patients with acute myocardial infarction: results from the GUSTO-III trial
    Sana M Al-Khatib
    Duke Clinical Research Institute, Durham, NC 27715, USA
    Am Heart J 145:515-21. 2003
    ..We studied the incidence, timing, and outcomes of such arrhythmias in the international Global Utilization of Streptokinase and TPA (alteplase) for Occluded Coronary Arteries (GUSTO)-III trial...
  78. ncbi Troponin T and quantitative ST-segment depression offer complementary prognostic information in the risk stratification of acute coronary syndrome patients
    Padma Kaul
    Duke Clinical Research Institute, Duke University, Durham, North Carolina, USA
    J Am Coll Cardiol 41:371-80. 2003
    ..4 vs. 1.5). CONCLUSIONS: Quantitative ST and cTnT status are complementary in assessing risk among ACS patients and both should be employed to determine prognosis and assist in medical decision making...
  79. ncbi Frequency, patient characteristics, and outcomes of mild-to-moderate heart failure complicating ST-segment elevation acute myocardial infarction: lessons from 4 international fibrinolytic therapy trials
    David Hasdai
    Rabin Medical Center, Petah Tikva, Israel
    Am Heart J 145:73-9. 2003
    ..38-1.74) and 2.15 times greater risk of death/re-MI (95% CI 1.96-2.36). CONCLUSION: Mild-to-moderate HF is a frequent and ominous complication of MI, especially when it does not resolve or develops after admission...
  80. ncbi Improving the care of patients with non-ST-elevation acute coronary syndromes in the emergency department: the CRUSADE initiative
    James W Hoekstra
    Ohio State University, Columbus, OH 43210, USA
    Acad Emerg Med 9:1146-55. 2002
    ..It is the intent of CRUSADE to improve patient care in the ED by tracking and encouraging compliance with evidence-based guidelines for the evaluation and management of NSTE ACS...
  81. ncbi Randomized COMparison of platelet inhibition with abciximab, tiRofiban and eptifibatide during percutaneous coronary intervention in acute coronary syndromes: the COMPARE trial. Comparison Of Measurements of Platelet aggregation with Aggrastat, Reopro, an
    Wayne B Batchelor
    Tallahassee Heart and Vascular Institute, Tallahassee Memorial Healthcare, Tallahassee, Fla 32308, USA
    Circulation 106:1470-6. 2002
    ..The relative anti-aggregatory effects of currently prescribed platelet glycoprotein IIb/IIIa receptor antagonists during and after percutaneous coronary intervention for acute coronary syndromes have not been established...
  82. ncbi Troponin T levels in patients with acute coronary syndromes, with or without renal dysfunction
    Ronnier J Aviles
    Department of Cardiology, The Cleveland Clinic Foundation, Cleveland, OH 44951, USA
    N Engl J Med 346:2047-52. 2002
    ..However, there is concern that renal dysfunction may impair the prognostic value, because cardiac troponin T may be cleared by the kidney...
  83. ncbi Racial variations in treatment and outcomes of black and white patients with high-risk non-ST-elevation acute coronary syndromes: insights from CRUSADE (Can Rapid Risk Stratification of Unstable Angina Patients Suppress Adverse Outcomes With Early Impleme
    Ali F Sonel
    Center for Health Equity Research and Promotion, Pittsburgh, PA, USA
    Circulation 111:1225-32. 2005
    ..It is unknown whether racial disparities exist for other treatments for non-ST-segment elevation acute coronary syndromes (NSTE ACS) and how different treatments affect outcomes...
  84. ncbi Influence of timing of troponin elevation on clinical outcomes and use of evidence-based therapies for patients with non-ST-segment elevation acute coronary syndromes
    Matthew T Roe
    Duke Clinical Research Institute, Durham, NC 27705, USA
    Ann Emerg Med 45:355-62. 2005
    ....
  85. ncbi Acute coronary care in the elderly, part I: Non-ST-segment-elevation acute coronary syndromes: a scientific statement for healthcare professionals from the American Heart Association Council on Clinical Cardiology: in collaboration with the Society of Ger
    Karen P Alexander
    Duke University Medical Center, USA
    Circulation 115:2549-69. 2007
    ..Reasons include limited trial data to guide the care of older adults and uncertainty about benefits and risks, particularly with newer medications or invasive treatments and in the setting of advanced age or complex health status...
  86. ncbi Heart failure with preserved left ventricular systolic function among patients with non-ST-segment elevation acute coronary syndromes
    Kyla M Bennett
    Duke Clinical Research Institute, Duke University Medical Center, Durham, North Carolina
    Am J Cardiol 99:1351-6. 2007
    ..Guideline-recommended therapies and interventions are under-utilized in patients with NSTE ACS and HF, with and without preserved systolic function, compared with those without HF...
  87. ncbi Characteristics, management, and outcomes of 5,557 patients age > or =90 years with acute coronary syndromes: results from the CRUSADE Initiative
    Adam H Skolnick
    Cardiovascular Division, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA
    J Am Coll Cardiol 49:1790-7. 2007
    ..The goal of this work was to explore the treatment and outcomes of patients with non-ST-segment elevation acute coronary syndromes (NSTE-ACS) age > or =90 years...
  88. ncbi One-year cardiovascular event rates in outpatients with atherothrombosis
    Ph Gabriel Steg
    Departement de Cardiologie, Hopital Bichat Claude Bernard, Paris, France
    JAMA 297:1197-206. 2007
    ....
  89. ncbi Bivalirudin in patients with acute coronary syndromes undergoing percutaneous coronary intervention: a subgroup analysis from the Acute Catheterization and Urgent Intervention Triage strategy (ACUITY) trial
    Gregg W Stone
    Columbia University Medical Center and the Cardiovascular Research Foundation, New York, NY 10022, USA
    Lancet 369:907-19. 2007
    ..The aim of this study was to assess anticoagulation with the direct thrombin inhibitor bivalirudin during percutaneous coronary intervention in individuals with moderate and high-risk acute coronary syndromes...
  90. ncbi Bivalirudin for patients with acute coronary syndromes
    Gregg W Stone
    Columbia University Medical Center and the Cardiovascular Research Foundation, New York, NY 10022, USA
    N Engl J Med 355:2203-16. 2006
    ..We evaluated the role of thrombin-specific anticoagulation with bivalirudin in such patients...
  91. ncbi Insurance coverage and care of patients with non-ST-segment elevation acute coronary syndromes
    James E Calvin
    Section of Cardiology, Rush University Medical Center, Chicago, Illinois 60612, USA
    Ann Intern Med 145:739-48. 2006
    ..The impact of insurance coverage on the care of patients with non-ST-segment elevation acute coronary syndromes (NSTE ACS) is unclear...
  92. ncbi Impact of carotid endarterectomy on medical secondary prevention after a stroke or a transient ischemic attack: results from the Reduction of Atherothrombosis for Continued Health (REACH) registry
    Emmanuel Touze
    Faculté de Médecine René Descartes, Universite Paris 5, EA 4055, Department of Neurology, Paris, France
    Stroke 37:2880-5. 2006
    ..Whether a history of carotid endarterectomy influences patient compliance with medical treatments and physician attitude toward treatments after ischemic stroke or transient ischemic attack (TIA) is not well known...
  93. ncbi Recent trends in the care of patients with non-ST-segment elevation acute coronary syndromes: insights from the CRUSADE initiative
    Rajendra H Mehta
    Duke Clinical Research Institute, Duke University Medical Center, Durham, NC 27715, USA
    Arch Intern Med 166:2027-34. 2006
    ..We sought to determine recent trends in adherence to guideline-based therapies for NSTE ACS...
  94. ncbi Prevalence, predictors, and outcomes of patients with non-ST-segment elevation myocardial infarction and insignificant coronary artery disease: results from the Can Rapid risk stratification of Unstable angina patients Suppress ADverse outcomes with Early
    Manesh R Patel
    Division of Cardiology and Duke Clinical Research Institute, Duke University Medical Center, Durham, NC 27705, USA
    Am Heart J 152:641-7. 2006
    ..We sought to determine the prevalence, predictors, and outcomes of patients with NSTEMI and insignificant CAD...
  95. ncbi Sex differences in major bleeding with glycoprotein IIb/IIIa inhibitors: results from the CRUSADE (Can Rapid risk stratification of Unstable angina patients Suppress ADverse outcomes with Early implementation of the ACC/AHA guidelines) initiative
    Karen P Alexander
    Duke Clinical Research Institute, Duke University Medical Center, Durham, NC 27715, USA
    Circulation 114:1380-7. 2006
    ..The contribution of dosing to the observed sex-related differences in bleeding is unknown...
  96. ncbi Acute clopidogrel use and outcomes in patients with non-ST-segment elevation acute coronary syndromes undergoing coronary artery bypass surgery
    Rajendra H Mehta
    Division of Cardiology and the Duke Clinical Research Institute, Durham, North Carolina 27715, USA
    J Am Coll Cardiol 48:281-6. 2006
    ....
  97. ncbi The obesity paradox in non-ST-segment elevation acute coronary syndromes: results from the Can Rapid risk stratification of Unstable angina patients Suppress ADverse outcomes with Early implementation of the American College of Cardiology/American Heart A
    Deborah B Diercks
    Department of Emergency Medicine, University of California, Davis, School of Medicine, Sacramento, CA, USA
    Am Heart J 152:140-8. 2006
    ..Although obesity is a known risk factor for coronary artery disease, its impact on the presentation, treatment, and outcome of patients with acute coronary syndromes (ACS) has not been well studied...
  98. ncbi Impact of congestive heart failure in patients with non-ST-segment elevation acute coronary syndromes
    Matthew T Roe
    Division of Cardiology and Duke Clinical Research Institute, Duke University Medical Center, Durham, North Carolina, USA
    Am J Cardiol 97:1707-12. 2006
    ..Further study is needed to determine the causes of these treatment differences and the optimal therapeutic approach for patients with NSTE ACS and concomitant CHF...
  99. ncbi Treatment disparities in the care of patients with and without diabetes presenting with non-ST-segment elevation acute coronary syndromes
    Gerard X Brogan
    Department of Emergency Medicine, New York University School of Medicine North Shore Long Island Jewish Health System, Plainview, New York 11803, USA
    Diabetes Care 29:9-14. 2006
    ..The objective of this study was to characterize treatment patterns among patients with diabetes presenting with non-ST-segment elevation (NSTE) acute coronary syndromes (ACSs)...
  100. ncbi Relationship between risk stratification by cardiac troponin level and adherence to guidelines for non-ST-segment elevation acute coronary syndromes
    Matthew T Roe
    Division of Cardiology and Duke Clinical Research Institute, Duke University Medical Center, Durham, NC 27705, USA
    Arch Intern Med 165:1870-6. 2005
    ..The threshold of troponin elevation that stimulates changes in clinical decision making for patients with non-ST-segment elevation acute coronary syndromes (NSTE ACSs) has not been previously evaluated...
  101. ncbi Influence of clinical trial enrollment on the quality of care and outcomes for patients with non-ST-segment elevation acute coronary syndromes
    David E Kandzari
    Duke Clinical Research Institute, Duke University Medical Center, Durham, NC 27705, USA
    Am Heart J 149:474-81. 2005
    ....