Research Topics
| Dennis H OhSummaryAffiliation: University of California Country: USA Publications
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Detail Information
Publications
Spatially localized generation of nucleotide sequence-specific DNA damageD H Oh
Department of Dermatology, University of California, San Francisco, CA 94143, USA
Proc Natl Acad Sci U S A 98:11271-6. 2001..This approach for targeting photochemical DNA damage may have photochemotherapeutic applications in skin and other optically accessible tissues...
Vitamin D in cutaneous carcinogenesis: part IIJean Y Tang
Department of Dermatology, Stanford University, Stanford, California 94305, USA
J Am Acad Dermatol 67:817.e1-11; quiz 827-8. 2012....
Defective DNA repair and cell cycle arrest in cells expressing Merkel cell polyomavirus T antigenStephanie K Demetriou
Department of Dermatology, University of California, San Francisco, CA, USA
Int J Cancer 131:1818-27. 2012..These results indicate that T antigen expression by MCV can inhibit key responses to UVR-induced DNA damage and suggest that progressive MCV-mediated abrogation of genomic stability may be involved in Merkel cell carcinogenesis...
gamma-H2AX formation in response to interstrand crosslinks requires XPF in human cellsSeiki Mogi
Department of Dermatology, University of California, San Francisco, USA
DNA Repair (Amst) 5:731-40. 2006..Furthermore, XPA may be important to allow psoralen interstrand crosslinks to be processed without forming a double strand break intermediate...
DNA polymerase eta reduces the gamma-H2AX response to psoralen interstrand crosslinks in human cellsSeiki Mogi
Department of Dermatology, University of California, San Francisco, and Dermatology Research Unit, San Francisco VA Medical Center 94121, USA
Exp Cell Res 314:887-95. 2008....
Proficient global nucleotide excision repair in human keratinocytes but not in fibroblasts deficient in p53Bridget E Ferguson
Department of Dermatology, University of California-San Francisco, San Francisco VA Medical Center, San Francisco, California 94121, USA
Cancer Res 65:8723-9. 2005..Collectively, these results indicate that human keratinocytes, unlike fibroblasts, do not require p53 to maintain basal global NER activity, but p53 may still be important in mediating inducible responses following DNA damage...
Functional relevance of the histone gammaH2Ax in the response to DNA damaging agentsIngrid Revet
Department of Dermatology, University of California, San Francisco, CA 94143 0808, USA
Proc Natl Acad Sci U S A 108:8663-7. 2011....
Modulation of psoralen DNA crosslinking kinetics associated with a triplex-forming oligonucleotideDennis H Oh
Department of Dermatology, University of California, San Francisco, and Dermatology Research Unit, San Francisco VA Medical Center, San Francisco, CA, USA
Photochem Photobiol 84:727-33. 2008....
Impaired repair of cyclobutane pyrimidine dimers in human keratinocytes deficient in p53 and p63Bridget E Ferguson-Yates
Department of Dermatology, University of California, San Francisco, CA, USA
Carcinogenesis 29:70-5. 2008..The results may provide insight into mechanisms of genomic stability in epithelia infected with oncogenic human papilloma viruses and may further explain the lack of increased skin cancer incidence in Li-Fraumeni syndrome...
Vitamin D in cutaneous carcinogenesis: part IJean Y Tang
Department of Dermatology, Stanford University, Stanford, CA 94305, USA
J Am Acad Dermatol 67:803.e1-12, quiz 815-6. 2012..Part I will review the role of vitamin D in the epidermis; part II will review the role of vitamin D in keratinocyte-derived tumors to help frame the discussion on the possible role of vitamin D in the prevention of skin cancer...
State of teledermatology programs in the United StatesApril W Armstrong
Department of Dermatology, University of California Davis Health System, Sacramento, California 95816, USA
J Am Acad Dermatol 67:939-44. 2012..Teledermatology programs in the United States have evolved over the past several decades. No systematic survey of teledermatology programs in the United States is available in peer-reviewed literature...
Hereditary photodermatosesDennis H Oh
Department of Dermatology, University of California at San Francisco, USA
Adv Exp Med Biol 685:95-105. 2010..Special emphasis will be placed on the relatively recently described UV-sensitive syndrome...
Differentiating human keratinocytes are deficient in p53 but retain global nucleotide excision repair following ultraviolet radiationDennis H Oh
Department of Dermatology, University of California, San Francisco, CA, USA
DNA Repair (Amst) 4:1149-59. 2005....
Basal cell carcinomas arising within multiple trichoepitheliomasLaura B Pincus
Department of Dermatology, University of California San Francisco, San Francisco, CA, USA
J Cutan Pathol 35:59-64. 2008..This report is a compelling example of MFT in which BCCs evolved secondarily. Awareness of the potential for the evolution of carcinoma in patients with MFT is important in the management of these patients...
Spatial control of reactive oxygen species formation in fibroblasts using two-photon excitationBrett A King
Department of Dermatology, University of California-San Francisco, San Francisco, CA, USA
Photochem Photobiol 80:1-6. 2004..This technique should be useful in understanding the response of whole tissues such as skin to local generation of ROS and may have applications in photodynamic therapy...
The impact of store-and-forward teledermatology on skin cancer diagnosis and treatmentJennifer L Hsiao
Dermatology Research Unit, VA Medical Center, San Francisco, California, USA
J Am Acad Dermatol 59:260-7. 2008..Although the diagnostic accuracy of teledermatology has been extensively studied, the clinical outcomes associated with teledermatology are still unclear...
