Brendan O'Fallon

Summary

Affiliation: University of Washington
Country: USA

Publications

  1. doi request reprint A continuous-state coalescent and the impact of weak selection on the structure of gene genealogies
    Brendan D O'Fallon
    Department of Genome Sciences, University of Washington, USA
    Mol Biol Evol 27:1162-72. 2010
  2. doi request reprint A method to correct for the effects of purifying selection on genealogical inference
    Brendan D O'Fallon
    Department of Genome Sciences, University of Washington, USA
    Mol Biol Evol 27:2406-16. 2010
  3. doi request reprint TreesimJ: a flexible, forward time population genetic simulator
    Brendan O'Fallon
    Department of Genome Sciences, Foege Building S 250, Box 355065 3720 15th Ave NE, Seattle, WA 98195 5065, USA
    Bioinformatics 26:2200-1. 2010
  4. doi request reprint Two optimal mutation rates in obligate pathogens subject to deleterious mutation
    Brendan O'Fallon
    Department of Genome Sciences, University of Washington, Seattle, WA 98195, USA
    J Theor Biol 276:150-8. 2011
  5. doi request reprint A method for accurate inference of population size from serially sampled genealogies distorted by selection
    Brendan D O'Fallon
    Department of Genome Sciences, University of Washington
    Mol Biol Evol 28:3171-81. 2011
  6. pmc Native Americans experienced a strong population bottleneck coincident with European contact
    Brendan D O'Fallon
    Department of Genome Sciences, University of Washington, Seattle, WA 98195, USA
    Proc Natl Acad Sci U S A 108:20444-8. 2011

Detail Information

Publications6

  1. doi request reprint A continuous-state coalescent and the impact of weak selection on the structure of gene genealogies
    Brendan D O'Fallon
    Department of Genome Sciences, University of Washington, USA
    Mol Biol Evol 27:1162-72. 2010
    ..Additionally, we demonstrate that only two parameters, population size and the variance of the distribution describing fitness heritability, are sufficient to describe most changes...
  2. doi request reprint A method to correct for the effects of purifying selection on genealogical inference
    Brendan D O'Fallon
    Department of Genome Sciences, University of Washington, USA
    Mol Biol Evol 27:2406-16. 2010
    ..I also compare the performance of the new method to relaxed clock models, and I demonstrate the method on a data set from the mitochondrion of the North Atlantic whale-"louse" Cyamus ovalis...
  3. doi request reprint TreesimJ: a flexible, forward time population genetic simulator
    Brendan O'Fallon
    Department of Genome Sciences, Foege Building S 250, Box 355065 3720 15th Ave NE, Seattle, WA 98195 5065, USA
    Bioinformatics 26:2200-1. 2010
    ..Thus, few tools are available that allow for producing genealogies under arbitrarily complex selective and demographic models...
  4. doi request reprint Two optimal mutation rates in obligate pathogens subject to deleterious mutation
    Brendan O'Fallon
    Department of Genome Sciences, University of Washington, Seattle, WA 98195, USA
    J Theor Biol 276:150-8. 2011
    ..Both chronic and acute infections are examined using stochastic forward simulations...
  5. doi request reprint A method for accurate inference of population size from serially sampled genealogies distorted by selection
    Brendan D O'Fallon
    Department of Genome Sciences, University of Washington
    Mol Biol Evol 28:3171-81. 2011
    ..Using the new method, I investigate two sets of dengue virus sequences from Puerto Rico and Thailand, and show that both genealogies are likely to have been distorted by selection...
  6. pmc Native Americans experienced a strong population bottleneck coincident with European contact
    Brendan D O'Fallon
    Department of Genome Sciences, University of Washington, Seattle, WA 98195, USA
    Proc Natl Acad Sci U S A 108:20444-8. 2011
    ..These results support analyses of historical records indicating that European colonization induced widespread mortality among indigenous Americans...