Greg Odorizzi

Summary

Affiliation: University of Colorado
Country: USA

Publications

  1. ncbi The multiple personalities of Alix
    Greg Odorizzi
    Molecular, Cellular, and Developmental Biology, University of Colorado, Boulder, CO 80309 0347, USA
    J Cell Sci 119:3025-32. 2006
  2. doi ESCRTs take on a job in surveillance
    Greg Odorizzi
    Department of Molecular, Cellular, and Developmental Biology, University of Colorado, Boulder, CO 80309 0347, USA Electronic address
    Cell 159:240-1. 2014
  3. ncbi Bro1 is an endosome-associated protein that functions in the MVB pathway in Saccharomyces cerevisiae
    Greg Odorizzi
    Department of Molecular, Cellular and Developmental Biology, University of Colorado, Campus Box 347, Boulder, CO 80309, USA
    J Cell Sci 116:1893-903. 2003
  4. pmc Dual mechanisms specify Doa4-mediated deubiquitination at multivesicular bodies
    Caleb Richter
    Department of Molecular, Cellular, and Developmental Biology, University of Colorado, Boulder, CO 80309, USA
    EMBO J 26:2454-64. 2007
  5. pmc Bro1 binding to Snf7 regulates ESCRT-III membrane scission activity in yeast
    Megan Wemmer
    Molecular, Cellular, and Developmental Biology, University of Colorado, Boulder, CO 80309, USA
    J Cell Biol 192:295-306. 2011
  6. pmc Doa4 function in ILV budding is restricted through its interaction with the Vps20 subunit of ESCRT-III
    Caleb M Richter
    Molecular, Cellular, and Developmental Biology, University of Colorado, Boulder, CO 80309, USA
    J Cell Sci 126:1881-90. 2013
  7. pmc Regulators of Vps4 ATPase activity at endosomes differentially influence the size and rate of formation of intralumenal vesicles
    Daniel P Nickerson
    Molecular, Cellular and Developmental Biology, University of Colorado, Boulder, CO 80309 0347, USA
    Mol Biol Cell 21:1023-32. 2010
  8. pmc Bro1 coordinates deubiquitination in the multivesicular body pathway by recruiting Doa4 to endosomes
    Natalie Luhtala
    Molecular, Cellular, and Developmental Biology, 347 UCB, University of Colorado, Boulder, CO 80309 0347, USA
    J Cell Biol 166:717-29. 2004
  9. pmc Class E compartments form in response to ESCRT dysfunction in yeast due to hyperactivity of the Vps21 Rab GTPase
    Matthew R G Russell
    Department of Molecular, Cellular and Developmental Biology, University of Colorado at Boulder, Campus Box 347, Boulder, CO 80309, USA
    J Cell Sci 125:5208-20. 2012
  10. pmc Direct binding to Rsp5 mediates ubiquitin-independent sorting of Sna3 via the multivesicular body pathway
    Matthew W McNatt
    Molecular, Cellular, and Developmental Biology, University of Colorado, Boulder, CO 80309 0347, USA
    Mol Biol Cell 18:697-706. 2007

Collaborators

  • Scott D Emr
  • Markus Babst
  • David Katzmann
  • Anjon Audhya
  • Daniel P Nickerson
  • Matthew West
  • Matthew R G Russell
  • Caleb M Richter
  • Megan Wemmer
  • Caleb Richter
  • Matthew W McNatt
  • Matthew Robert Geoffrey Russell
  • Natalie Luhtala
  • Tess Shideler
  • Matt West
  • Brian Davies
  • Ishara Azmi
  • Ryan Henry
  • Ian McKittrick
  • Daniel Patrick Nickerson

Detail Information

Publications13

  1. ncbi The multiple personalities of Alix
    Greg Odorizzi
    Molecular, Cellular, and Developmental Biology, University of Colorado, Boulder, CO 80309 0347, USA
    J Cell Sci 119:3025-32. 2006
    ..With this blueprint in hand, we can now ask whether Alix acts simply as an adaptor that links different proteins into networks or, instead, contributes a specific function to distinct molecular machineries...
  2. doi ESCRTs take on a job in surveillance
    Greg Odorizzi
    Department of Molecular, Cellular, and Developmental Biology, University of Colorado, Boulder, CO 80309 0347, USA Electronic address
    Cell 159:240-1. 2014
    ..In this issue, Lusk and colleagues describe a surveillance pathway during nuclear pore assembly and, in doing so, identify a new role for proteins that function at the endosome and plasma membrane...
  3. ncbi Bro1 is an endosome-associated protein that functions in the MVB pathway in Saccharomyces cerevisiae
    Greg Odorizzi
    Department of Molecular, Cellular and Developmental Biology, University of Colorado, Campus Box 347, Boulder, CO 80309, USA
    J Cell Sci 116:1893-903. 2003
    ..Our data suggest that the function of Bro1 in the MVB pathway takes place on endosomal membranes and occurs in concert with or downstream of the function of the ESCRT-III complex...
  4. pmc Dual mechanisms specify Doa4-mediated deubiquitination at multivesicular bodies
    Caleb Richter
    Department of Molecular, Cellular, and Developmental Biology, University of Colorado, Boulder, CO 80309, USA
    EMBO J 26:2454-64. 2007
    ..Thus, by recruiting Doa4 to late endosomes and stimulating its catalytic activity, Bro1 fulfills a novel dual role in coordinating deubiquitination in the MVB pathway...
  5. pmc Bro1 binding to Snf7 regulates ESCRT-III membrane scission activity in yeast
    Megan Wemmer
    Molecular, Cellular, and Developmental Biology, University of Colorado, Boulder, CO 80309, USA
    J Cell Biol 192:295-306. 2011
    ..This stabilization effect correlates with a reduced frequency in the detachment of intralumenal vesicles as observed by electron tomography, implicating Bro1 as a regulator of ESCRT-III disassembly and membrane scission activity...
  6. pmc Doa4 function in ILV budding is restricted through its interaction with the Vps20 subunit of ESCRT-III
    Caleb M Richter
    Molecular, Cellular, and Developmental Biology, University of Colorado, Boulder, CO 80309, USA
    J Cell Sci 126:1881-90. 2013
    ..This rescue in ILV biogenesis requires Doa4 expression but is independent of its Ub hydrolase activity. Thus, binding of Vps20 to the Doa4 N-terminus inhibits a non-catalytic function of Doa4 that promotes ILV formation...
  7. pmc Regulators of Vps4 ATPase activity at endosomes differentially influence the size and rate of formation of intralumenal vesicles
    Daniel P Nickerson
    Molecular, Cellular and Developmental Biology, University of Colorado, Boulder, CO 80309 0347, USA
    Mol Biol Cell 21:1023-32. 2010
    ..These morphological effects probably result from Vps4-mediated manipulations of ESCRT-III, because we show dissociation of ESCRT-0, -I, and -II from endosomes is not directly dependent on Vps4 activity...
  8. pmc Bro1 coordinates deubiquitination in the multivesicular body pathway by recruiting Doa4 to endosomes
    Natalie Luhtala
    Molecular, Cellular, and Developmental Biology, 347 UCB, University of Colorado, Boulder, CO 80309 0347, USA
    J Cell Biol 166:717-29. 2004
    ..Thus, our results point to a key role for Bro1 in coordinating the timing and location of deubiquitination by Doa4 in the MVB pathway...
  9. pmc Class E compartments form in response to ESCRT dysfunction in yeast due to hyperactivity of the Vps21 Rab GTPase
    Matthew R G Russell
    Department of Molecular, Cellular and Developmental Biology, University of Colorado at Boulder, Campus Box 347, Boulder, CO 80309, USA
    J Cell Sci 125:5208-20. 2012
    ..Indeed, genetic disruption of Rab conversion without ESCRT dysfunction autonomously drives the class E compartment morphology without blocking ILV budding...
  10. pmc Direct binding to Rsp5 mediates ubiquitin-independent sorting of Sna3 via the multivesicular body pathway
    Matthew W McNatt
    Molecular, Cellular, and Developmental Biology, University of Colorado, Boulder, CO 80309 0347, USA
    Mol Biol Cell 18:697-706. 2007
    ....
  11. pmc Did2 coordinates Vps4-mediated dissociation of ESCRT-III from endosomes
    Daniel P Nickerson
    Department of Molecular, Cellular, and Developmental Biology, University of Colorado, Boulder, CO 80309, USA
    J Cell Biol 175:715-20. 2006
    ....
  12. pmc A concentric circle model of multivesicular body cargo sorting
    Daniel P Nickerson
    Department of Molecular, Cellular, and Developmental Biology, University of Colorado, 347 UCB, Boulder, Colorado 80309 0347, USA
    EMBO Rep 8:644-50. 2007
    ..Recent structural and functional studies of ESCRT complexes suggest an alternative model that might direct the next series of breakthroughs in understanding protein sorting through the MVB pathway...
  13. ncbi Molecular mechanisms of late endosome morphology, identity and sorting
    Matthew Robert Geoffrey Russell
    Molecular, Cellular, and Developmental Biology, 347 UCB, University of Colorado, Boulder, CO 80309 0347, USA
    Curr Opin Cell Biol 18:422-8. 2006
    ....