Research Topics
| Jon S OdoricoSummaryAffiliation: University of Wisconsin Country: USA Publications
| Collaborators
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Detail Information
Publications
Multilineage differentiation from human embryonic stem cell linesJ S Odorico
Department of Surgery, Department of Medicine, University of Wisconsin School of Medicine, Madison, Wisconsin 53792, USA
Stem Cells 19:193-204. 2001..Though human ES cell-based transplantation therapy holds great promise to successfully treat a variety of diseases (e.g., Parkinson's disease, diabetes, and heart failure) many barriers remain in the way of successful clinical trials...- Technical and immunosuppressive advances in transplantation for insulin-dependent diabetes mellitusJon S Odorico
Division of Organ Transplantation, Department of Surgery, University of Wisconsin Hospital and Clinics, H4 756 Clinical Science Center, 600 Highland Avenue, Madison, Wisconsin 53792, USA
World J Surg 26:194-211. 2002..Consequently, the American Diabetes Association strongly endorses pancreas transplantation in diabetic patients who have received prior kidney transplants and who have life-threatening metabolic lability... 
Donation after cardiac death: the University of Wisconsin experience with liver transplantationDavid P Foley
Department of Surgery, Division of Transplantation, University of Florida, Gainesville, FL, USA
Ann Surg 242:724-31. 2005..However, overall results of LTx after controlled DCD are encouraging; and with careful donor and recipient selection, LTx after DCD may successfully increase the donor liver pool...- Simultaneous pancreas-kidney transplantation from donation after cardiac death: successful long-term outcomesLuis A Fernandez
Division of Transplantation, University of Wisconsin Medical School, Madison, WI 53792-7375, USA
Ann Surg 242:716-23. 2005..CONCLUSION: SPK transplantation using selected DCD donors is a safe and viable method to expand the organ pool for transplantation... 
Alemtuzumab induction and antibody-mediated kidney rejection after simultaneous pancreas-kidney transplantationJulio Pascual
Division of Transplantation, Department of Surgery, University of Wisconsin School of Medicine and Public Health, Madison, WI 53713, USA
Transplantation 87:125-32. 2009..Alemtuzumab is effective in preventing acute cellular rejection (ACR) in SPK recipients and has been used to prevent antibody-mediated rejection (AMR) in sensitized kidney transplant candidates...- Superior long-term results of simultaneous pancreas-kidney transplantation from pediatric donorsLuis A Fernandez
Division of Transplantation, Department of Medicine, University of Wisconsin, 600 Highland Avenue, Madison, WI 53792 7375, USA
Am J Transplant 4:2093-101. 2004..15; pancreas 75% vs. 76%, p = 0.10, respectively). Pediatric donors represent a valuable source of organs, providing excellent short- and long-term outcomes. Wide utilization of pediatric organs will substantially increase the donor pool... - Outcomes at 3 years of a prospective pilot study of Campath-1H and sirolimus immunosuppression for renal transplantationRolf N Barth
Department of Surgery, Division of Transplantation, University of Wisconsin School of Medicine and Public Health, Madison, 53792-7375, USA
Transpl Int 19:885-92. 2006..Because of the higher incidence of early rejection, we recommend a modified strategy of immunosuppression including a brief course of a calcineurin inhibitor... - Campath-1H in renal transplantation: The University of Wisconsin experienceStuart J Knechtle
Department of Surgery, University of Winsconsin Medical School, Madison 53792-7375, USA
Surgery 136:754-60. 2004..CONCLUSIONS: Campath-1H was well tolerated in renal transplant patients and led to significant reductions in incidence of rejection. Patients with delayed graft function experienced significantly improved graft survival... - Differential outcomes of expanded-criteria donor renal allografts according to recipient ageJoshua D Mezrich
Department of Surgery, Division of Transplantation, University of Wisconsin School of Medicine and Public Health, Madison, WI 53792 7375, USA
Clin J Am Soc Nephrol 7:1163-71. 2012..This study sought to determine whether older recipients had significantly worse outcomes from receiving ECD kidneys and whether outcomes of ECD versus standard-criteria donor (SCD) kidneys differed in younger recipients... - Donation after cardiac death: a 29-year experienceJanet M Bellingham
Division of Organ Transplantation, University of Wisconsin School of Medicine and Public Health, Madison, WI 53792 7375, USA
Surgery 150:692-702. 2011..To report the long-term outcomes of 1218 organs transplanted from donation after cardiac death (DCD) donors from January 1980 through December 2008... - Donation after cardiac death: the University of Wisconsin experienceAnthony M D'Alessandro
Department of Surgery, University of Wisconsin Medical School, USA
Ann Transplant 9:68-71. 2004..The objective of this analysis was to compare the results of transplantation of livers, pancreases, kidneys, and lungs from donation after cardiac death (DCD) donors to organs transplanted from donation after brain death (DBD) donors... - Donation after cardiac death: the university of wisconsin experience with renal transplantationJeffrey T Cooper
Department of Surgery, Tufts University School of Medicine, Boston, MA, USA
Am J Transplant 4:1490-4. 2004..Organ procurement organizations, transplant centers, and hospitals should work to expand the implementation of DCD policies... - Chronic allograft nephropathy uniformly affects recipients of cadaveric, nonidentical living-related, and living-unrelated graftsNancy R Krieger
Department of Surgery, University of Wisconsin Medical School, Madison, WI 53792-7375, USA
Transplantation 75:1677-82. 2003..The disparities in overall graft survival, despite the similarities in CAN rates, suggests that other factors, in addition to CAN, influence the increase in graft loss in CAD transplant recipients... - Reduced serum concentration is permissive for increased in vitro endocrine differentiation from murine embryonic stem cellsRobert K Vincent
Division of Transplantation, Department of Surgery, University of Wisconsin School of Medicine and Public Health, Madison, WI 53792, USA
Differentiation 78:24-34. 2009..In summary, these data demonstrate that induced expression of key pancreatic transcription factors in combination with low serum/SR concentrations increases endocrine cell differentiation from murine ESCs... - One thousand simultaneous pancreas-kidney transplants at a single center with 22-year follow-upHans W Sollinger
Division of Transplantation, University of Wisconsin, Madison, WI 53792, USA
Ann Surg 250:618-30. 2009..The purpose of this study is to report long-term outcomes of this procedure, and describe surgical and medical complications... - Nasogastric decompression is not necessary after simultaneous pancreas-kidney transplantationRolf N Barth
Division of Transplantation, Department of Surgery, University of Maryland, Baltimore, MD, USA
Ann Surg 247:350-6. 2008..To determine whether eliminating routine nasogastric (NG) decompression after simultaneous pancreas-kidney (SPK) transplantation would reduce hospital length of stay without any increase in complications... - Antibody-mediated rejection of the kidney after simultaneous pancreas-kidney transplantationJulio Pascual
Department of Surgery, Division of Transplantation, University of Wisconsin Hospital and Clinics, H4 772 CSC, 600 Highland Avenue, Madison, WI 53792 7375, USA
J Am Soc Nephrol 19:812-24. 2008.... - Undifferentiated murine embryonic stem cells cannot induce portal tolerance but may possess immune privilege secondary to reduced major histocompatibility complex antigen expressionJoseph F Magliocca
Department of Surgery, Division of Transplantation, University of Wisconsin School of Medicine and Public Health, Madison, WI 53792, USA
Stem Cells Dev 15:707-17. 2006..ES cells appear to have immune privilege, allowing them to form teratomas in immunocompetent mice... - Underutilization of pancreas donorsNancy R Krieger
Division of Organ transplatation, Department of Surgery, University of Wisconsin Medical School, Madison, WI 53792, USA
Transplantation 75:1271-6. 2003..90% and 80%, P=0.006). CONCLUSIONS: This study demonstrates that utilization of pancreas grafts from selected, less-than-ideal donors results in good overall outcomes and could potentially expand the organ donor pool... - Activin, BMP and FGF pathways cooperate to promote endoderm and pancreatic lineage cell differentiation from human embryonic stem cellsXiaofang Xu
Department of Surgery, Division of Transplantation, University of Wisconsin Madison School of Medicine and Public Health, Wisconsin Institute of Medical Research, 600 Highland Ave, Madison, WI 53792, USA
Mech Dev 128:412-27. 2011..Our study identifies a new chemically defined culture protocol for inducing endoderm- and pancreas-committed cells from hESCs and reveals an interplay between FGF, Activin A and BMP signaling in early hESC fate determination... - Campath-1H induction plus rapamycin monotherapy for renal transplantation: results of a pilot studyStuart J Knechtle
Department of Surgery, University of Wisconsin Medical School, Madison, WI, USA
Am J Transplant 3:722-30. 2003..This clinical trial provides insight into the use of Campath-1H induction in combination with rapamycin maintenance monotherapy... - Simultaneous pancreas and kidney (SPK) retransplantation in prior SPK recipientsJohn C LaMattina
Division of Transplantation, University of Maryland School of Medicine, Baltimore, MD, USA
Clin Transplant 26:495-501. 2012..On the basis of these experiences, we began performing repeat SPK in prior SPK recipients (n = 9)... - Validation of large particle flow cytometry for the analysis and sorting of intact pancreatic isletsLuis A Fernandez
Department of Surgery, University of Wisconsin Madison, Madison, WI 53792 3236, USA
Transplantation 80:729-37. 2005..We evaluated Complex Object Parametric Analyzer and Sorter (COPAS) large particle flow cytometry for the determination of islet equivalent counts and purities of islet preparations... - Can 'extreme' pancreas donors expand the donor pool?Nikole A Neidlinger
University of Wisconsin Department of Surgery, Division of Organ Transplantation, Clinical Science Center, Madison, Wisconsin 53792 7375, USA
Curr Opin Organ Transplant 13:67-71. 2008..The present review investigates donor qualities that impact pancreas and islet transplantation, with a focus on donors that have been historically underutilized, including those of extreme age, extreme size, and donors after cardiac death... - Intrathymic injection of anti-Fas monoclonal antibody prolongs murine non-vascularized cardiac allograft survivalArjang Djamali
Department of Medicine, Nephrology Section, Division of Organ Transplantation, University of Wisconsin-Madison Medical School, Madison, Wisconsin 53792, USA
Transpl Int 17:301-9. 2004.... - A significant role for histocompatibility in human islet transplantationT Mohanakumar
Department of Surgery, Washington University School of Medicine, St Louis, MO 63110, USA
Transplantation 82:180-7. 2006..The purpose of this study was to determine the role of pretransplant sensitization to human leukocyte antigen (HLA) in islet transplantation... - Pancreatic precursors and differentiated islet cell types from murine embryonic stem cells: an in vitro model to study islet differentiationBrenda W Kahan
Department of Surgery, University of Wisconsin-Madison School of Medicine, Madison, Wisconsin, USA
Diabetes 52:2016-24. 2003.... - Surgical repair of transplant renal artery stenosis with preserved cadaveric iliac artery graftsBrian D Shames
Division of Transplantation, Department of Surgery, University of Wisconsin, Madison, 53792, USA
Ann Surg 237:116-22. 2003..To review the authors' experience with ABO-matched, preserved, cadaveric, iliac artery grafts for treatment of transplant renal artery stenosis (TRAS)... - Differentiation of embryonic stem cells conditionally expressing neurogenin 3Nathan R Treff
University of Wisconsin Madison School of Medicine and Public Health, Department of Surgery, Madison, Wisconsin, USA
Stem Cells 24:2529-37. 2006..0001) when compared with uninduced EBs. Moreover, we find that Ngn3 induction in differentiating ESCs results in significant increases in insulin, glucagon, and somatostatin expression... - Alternative sources of pluripotency: science, ethics, and stem cellsZachary J Kastenberg
Division of Transplantation, Department of Surgery, University of Wisconsin School of Medicine and Public Health and WiCell Research Institute, Madison, WI 53792, USA
Transplant Rev (Orlando) 22:215-22. 2008.... - Does propofol anesthesia affect intraoperative parathyroid hormone levels? A randomized, prospective trialRebecca S Sippel
Department of Surgery, University of Wisconsin Medical School, 600 Highland Avenue, Madison, WI 53792, USA
Surgery 136:1138-42. 2004..Several authors have reported that propofol can interfere with intact parathyroid hormone (PTH) testing in vitro. Therefore, many surgeons avoid propofol during parathyroidectomy...