CHESTER V contact ODDIS

Summary

Affiliation: University of Pittsburgh
Country: USA

Publications

  1. pmc In adult onset myositis, the presence of interstitial lung disease and myositis specific/associated antibodies are governed by HLA class II haplotype, rather than by myositis subtype
    Hector Chinoy
    Rheumatic Diseases Centre, Hope Hospital, Salford, UK
    Arthritis Res Ther 8:R13. 2006
  2. ncbi request reprint International consensus guidelines for trials of therapies in the idiopathic inflammatory myopathies
    Chester V Oddis
    University of Pittsburgh, Pittsburgh, Pennsylvania 15261, USA
    Arthritis Rheum 52:2607-15. 2005
  3. ncbi request reprint Outcomes and disease activity measures for assessing treatments in the idiopathic inflammatory myopathies
    Chester V Oddis
    University of Pittsburgh School of Medicine, Division of Rheumatology and Clinical Immunology, South 703, Biomedical Science Tower, 3500 Terrace Street, Pittsburgh, PA 15261, USA
    Curr Rheumatol Rep 7:87-93. 2005
  4. ncbi request reprint Critical requirement for professional APCs in eliciting T cell responses to novel fragments of histidyl-tRNA synthetase (Jo-1) in Jo-1 antibody-positive polymyositis
    Dana P Ascherman
    Division of Rheumatology and Clinical Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15261, USA
    J Immunol 169:7127-34. 2002
  5. ncbi request reprint Idiopathic inflammatory myopathy: management and prognosis
    Chester V Oddis
    Division of Rheumatology and Clinical Immunology, Department of Medicine, University of Pittsburgh School of Medicine, S703 Biomedical Science Tower, 3500 Terrace Street, Pittsburgh, PA 15261, USA
    Rheum Dis Clin North Am 28:979-1001. 2002
  6. ncbi request reprint Idiopathic inflammatory myopathies: a treatment update
    Chester V Oddis
    Department of Medicine, Division of Rheumatology and Clinical Immunology, University of Pittsburgh School of Medicine, S703 Biomedical Science Tower, 3500 Terrace Street, Pittsburgh, PA 15261, USA
    Curr Rheumatol Rep 5:431-6. 2003
  7. ncbi request reprint Treatment of antisynthetase-associated interstitial lung disease with tacrolimus
    Margaret R Wilkes
    University of Pittsburgh, PA 15261, USA
    Arthritis Rheum 52:2439-46. 2005
  8. pmc Characterization and peripheral blood biomarker assessment of anti-Jo-1 antibody-positive interstitial lung disease
    Thomas J Richards
    University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15261, USA
    Arthritis Rheum 60:2183-92. 2009
  9. ncbi request reprint Anti-Jo-1 antibody levels correlate with disease activity in idiopathic inflammatory myopathy
    Kerry B Stone
    University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15261, USA
    Arthritis Rheum 56:3125-31. 2007
  10. ncbi request reprint Anti-signal recognition particle autoantibody in patients with and patients without idiopathic inflammatory myopathy
    Amy H Kao
    University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15261, USA
    Arthritis Rheum 50:209-15. 2004

Research Grants

Collaborators

Detail Information

Publications25

  1. pmc In adult onset myositis, the presence of interstitial lung disease and myositis specific/associated antibodies are governed by HLA class II haplotype, rather than by myositis subtype
    Hector Chinoy
    Rheumatic Diseases Centre, Hope Hospital, Salford, UK
    Arthritis Res Ther 8:R13. 2006
    ..In conclusion, these findings support the notion that myositis patients with differing myositis serology have different immunogenetic profiles, and that these profiles may define specific myositis subtypes...
  2. ncbi request reprint International consensus guidelines for trials of therapies in the idiopathic inflammatory myopathies
    Chester V Oddis
    University of Pittsburgh, Pittsburgh, Pennsylvania 15261, USA
    Arthritis Rheum 52:2607-15. 2005
  3. ncbi request reprint Outcomes and disease activity measures for assessing treatments in the idiopathic inflammatory myopathies
    Chester V Oddis
    University of Pittsburgh School of Medicine, Division of Rheumatology and Clinical Immunology, South 703, Biomedical Science Tower, 3500 Terrace Street, Pittsburgh, PA 15261, USA
    Curr Rheumatol Rep 7:87-93. 2005
    ..The final step in the puzzle of well-designed therapeutic trials in myositis is the determination of consensus guidelines to conduct such trials in adult and pediatric populations of myositis patients...
  4. ncbi request reprint Critical requirement for professional APCs in eliciting T cell responses to novel fragments of histidyl-tRNA synthetase (Jo-1) in Jo-1 antibody-positive polymyositis
    Dana P Ascherman
    Division of Rheumatology and Clinical Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15261, USA
    J Immunol 169:7127-34. 2002
    ..More importantly, this work underscores the critical importance of APC type in dictating T cell responses to a novel antigenic fragment of Jo-1...
  5. ncbi request reprint Idiopathic inflammatory myopathy: management and prognosis
    Chester V Oddis
    Division of Rheumatology and Clinical Immunology, Department of Medicine, University of Pittsburgh School of Medicine, S703 Biomedical Science Tower, 3500 Terrace Street, Pittsburgh, PA 15261, USA
    Rheum Dis Clin North Am 28:979-1001. 2002
    ....
  6. ncbi request reprint Idiopathic inflammatory myopathies: a treatment update
    Chester V Oddis
    Department of Medicine, Division of Rheumatology and Clinical Immunology, University of Pittsburgh School of Medicine, S703 Biomedical Science Tower, 3500 Terrace Street, Pittsburgh, PA 15261, USA
    Curr Rheumatol Rep 5:431-6. 2003
    ..Rehabilitative measures are often overlooked in the treatment of myositis, but may significantly improve the functional outcome of patients with these disorders...
  7. ncbi request reprint Treatment of antisynthetase-associated interstitial lung disease with tacrolimus
    Margaret R Wilkes
    University of Pittsburgh, PA 15261, USA
    Arthritis Rheum 52:2439-46. 2005
    ..A statistically significant reduction in the corticosteroid dosage was also observed. CONCLUSION: Tacrolimus is a well-tolerated and effective therapy for managing refractory ILD and myositis in anti-aaRS-positive patients...
  8. pmc Characterization and peripheral blood biomarker assessment of anti-Jo-1 antibody-positive interstitial lung disease
    Thomas J Richards
    University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15261, USA
    Arthritis Rheum 60:2183-92. 2009
    ....
  9. ncbi request reprint Anti-Jo-1 antibody levels correlate with disease activity in idiopathic inflammatory myopathy
    Kerry B Stone
    University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15261, USA
    Arthritis Rheum 56:3125-31. 2007
    ....
  10. ncbi request reprint Anti-signal recognition particle autoantibody in patients with and patients without idiopathic inflammatory myopathy
    Amy H Kao
    University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15261, USA
    Arthritis Rheum 50:209-15. 2004
    ..To determine the long-term outcome and associated clinical, serologic, and pathologic features in a cohort of patients with connective tissue disease (CTD) and the anti-signal recognition particle (anti-SRP) autoantibody...
  11. doi request reprint Anti-U3 RNP autoantibodies in systemic sclerosis
    Rohit Aggarwal
    University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA
    Arthritis Rheum 60:1112-8. 2009
    ..To describe the classification, demographic and clinical features, and survival in anti-U3 RNP autoantibody-positive patients with systemic sclerosis (SSc)...
  12. doi request reprint The pulmonary histopathologic manifestations of the anti-Jo-1 tRNA synthetase syndrome
    Samuel A Yousem
    Department of Pathology, UPMC Presbyterian Shadyside, Pittsburgh, PA 15213 2582, USA
    Mod Pathol 23:874-80. 2010
    ....
  13. ncbi request reprint HLA polymorphisms in African Americans with idiopathic inflammatory myopathy: allelic profiles distinguish patients with different clinical phenotypes and myositis autoantibodies
    Terrance P O'Hanlon
    National Institute of Environmental Health Sciences, Bethesda, Maryland 20892, USA
    Arthritis Rheum 54:3670-81. 2006
    ..To investigate possible associations of HLA polymorphisms with idiopathic inflammatory myopathy (IIM) in African Americans, and to compare this with HLA associations in European American IIM patients with IIM...
  14. ncbi request reprint Novel autoantibodies against 7SL RNA in patients with polymyositis/dermatomyositis
    Takashi Satoh
    Department of Laboratory Medicine, Kitasato University School of Medicine, Sagamihara, Kanagawa, Japan
    J Rheumatol 32:1727-33. 2005
    ..We examined autoantibodies against deproteinized 7SL RNA in PM/DM patients with anti-SRP antibodies and evaluated the association of anti-7SL RNA antibodies with PM/DM clinically and serologically...
  15. pmc The diagnostic utility of myositis autoantibody testing for predicting the risk of cancer-associated myositis
    Hector Chinoy
    Rheumatic Diseases Centre, Hope Hospital, The University of Manchester, Salford, UK
    Ann Rheum Dis 66:1345-9. 2007
    ..This study was undertaken to determine whether risk of developing cancer in myositis can be predicted by antibody profiling...
  16. ncbi request reprint Subject retention and adherence in a randomized placebo-controlled trial of a disease-modifying osteoarthritis drug
    Steven A Mazzuca
    Indiana University School of Medicine, Indianapolis, 46202 5100, USA
    Arthritis Rheum 51:933-40. 2004
    ..To describe the methods by which remarkable levels of subject retention and adherence were achieved in a 30-month multicenter randomized placebo-controlled trial (RCT) of a disease-modifying osteoarthritis drug (DMOAD)...
  17. ncbi request reprint Diagnostic criteria for polymyositis and dermatomyositis
    Frederick W Miller
    Lancet 362:1762-3; author reply 1763. 2003
  18. ncbi request reprint Autoantibodies to a 140-kd polypeptide, CADM-140, in Japanese patients with clinically amyopathic dermatomyositis
    Shinji Sato
    Keio University School of Medicine, Tokyo, Japan
    Arthritis Rheum 52:1571-6. 2005
    ..To identify novel autoantibodies specific for dermatomyositis (DM), especially those specific for clinically amyopathic DM (C-ADM)...
  19. pmc Interferon-gamma and interleukin-4 gene polymorphisms in Caucasian idiopathic inflammatory myopathy patients in UK
    Hector Chinoy
    The University of Manchester Rheumatic Diseases Centre, Salford M6 8HD, UK
    Ann Rheum Dis 66:970-3. 2007
    ..To determine whether interferon-gamma (IFN-gamma) and interleukin-4 (IL-4) genes confer susceptibility for the idiopathic inflammatory myopathies (IIMs)...
  20. ncbi request reprint Severity of joint pain and Kellgren-Lawrence grade at baseline are better predictors of joint space narrowing than bone scintigraphy in obese women with knee osteoarthritis
    Steven A Mazzuca
    Department of Medicine, Indiana University School of Medicine IUSM, Indianapolis, 46202, USA
    J Rheumatol 32:1540-6. 2005
    ....
  21. ncbi request reprint Immunogenetic risk and protective factors for the idiopathic inflammatory myopathies: distinct HLA-A, -B, -Cw, -DRB1, and -DQA1 allelic profiles distinguish European American patients with different myositis autoantibodies
    Terrance P O'Hanlon
    National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland 20892, USA
    Medicine (Baltimore) 85:111-27. 2006
    ....
  22. ncbi request reprint Effects of doxycycline on progression of osteoarthritis: results of a randomized, placebo-controlled, double-blind trial
    Kenneth D Brandt
    Indiana University School of Medicine, Rheumatology Division, Indianapolis, IN 46202 5100, USA
    Arthritis Rheum 52:2015-25. 2005
    ..To confirm preclinical data suggesting that doxycycline can slow the progression of osteoarthritis (OA). The primary outcome measure was joint space narrowing (JSN) in the medial tibiofemoral compartment...
  23. ncbi request reprint Glucosamine, chondroitin sulfate, and the two in combination for painful knee osteoarthritis
    Daniel O Clegg
    Division of Rheumatology, University of Utah School of Medicine, Salt Lake City, UT 84132, USA
    N Engl J Med 354:795-808. 2006
    ..The multicenter, double-blind, placebo- and celecoxib-controlled Glucosamine/chondroitin Arthritis Intervention Trial (GAIT) evaluated their efficacy and safety as a treatment for knee pain from osteoarthritis...
  24. ncbi request reprint Seasonal influence on the onset of idiopathic inflammatory myopathies in serologically defined groups
    Kakali Sarkar
    National Institute of Environmental Health Sciences, NIH, DHHS, Bethesda, MD 20892, USA
    Arthritis Rheum 52:2433-8. 2005
    ..To assess possible seasonal patterns in the onset of polymyositis (PM) and dermatomyositis (DM)...
  25. ncbi request reprint Immunogenetic risk and protective factors for the idiopathic inflammatory myopathies: distinct HLA-A, -B, -Cw, -DRB1 and -DQA1 allelic profiles and motifs define clinicopathologic groups in caucasians
    Terrance P O'Hanlon
    National Institute of Environmental Health Sciences, Rockville, MD 20892 0958, USA
    Medicine (Baltimore) 84:338-49. 2005
    ..These variations in associated HLA polymorphisms may reflect responses to unique environmental triggers resulting in the tissue pathospecificity and distinct clinicopathologic syndromes of the IIM...

Research Grants1

  1. Mechanisms of Response and Relapse in Rituximab-treated Myositis Patients
    CHESTER V contact ODDIS; Fiscal Year: 2010
    ..This application will determine the mechanisms by which rituximab works using samples collected from myositis subjects treated with rituximab in the RIM study. ..