Mary Frances O'Connor

Summary

Affiliation: University of California
Country: USA

Publications

  1. ncbi Baseline vagal tone predicts BOLD response during elicitation of grief
    Mary Frances O'Connor
    UCLA Neuropsychiatric Institute, Cousins Center for Psychoneuroimmunology, Los Angeles, CA 90095 7076, USA
    Neuropsychopharmacology 32:2184-9. 2007
  2. ncbi Bereavement and the brain: invitation to a conversation between bereavement researchers and neuroscientists
    Mary Frances O'Connor
    Neuropsychiatric Institute, Cousins Center for Psychoneuroimmunology, UCLA, 300 Medical Plaza, Room 3156, Los Angeles, CA 90095 7076, USA
    Death Stud 29:905-22. 2005
  3. pmc Immunological and neuroimaging biomarkers of complicated grief
    Mary Frances O'Connor
    Cousins Center for Psychoneuroimmunology, Semel Institute for Neuroscience and Human Behavior, University of California at Los Angeles, Los Angeles, CA, USA
    Dialogues Clin Neurosci 14:141-8. 2012
  4. pmc Diurnal cortisol in Complicated and Non-Complicated Grief: slope differences across the day
    Mary Frances O'Connor
    Cousins Center for Psychoneuroimmunology, UCLA Semel Institute for Neuroscience and Human Behavior, Los Angeles, CA, United States
    Psychoneuroendocrinology 37:725-8. 2012
  5. pmc Links between behavioral factors and inflammation
    M F O'Connor
    Cousins Center for Psychoneuroimmunology, Semel Institute for Neuroscience and Human Behavior, University of California at Los Angeles, Los Angeles, California, USA
    Clin Pharmacol Ther 87:479-82. 2010
  6. pmc When grief heats up: pro-inflammatory cytokines predict regional brain activation
    Mary Frances O'Connor
    Cousins Center for Psychoneuroimmunology, Semel Institute for Neuroscience and Human Behavior, University of California at Los Angeles, USA
    Neuroimage 47:891-6. 2009
  7. pmc Craving love? Enduring grief activates brain's reward center
    Mary Frances O'Connor
    Cousins Center for Psychoneuroimmunology, Semel Institute for Neuroscience and Human Behavior, University of California at Los Angeles, USA
    Neuroimage 42:969-72. 2008
  8. ncbi Sex differences in monocyte expression of IL-6: role of autonomic mechanisms
    Mary Frances O'Connor
    Cousins Center for Psychoneuroimmunology, UCLA Semel Institute for Neuroscience and Human Behavior, University of California Los Angeles, 300 Medical Plaza, Los Angeles, CA 90095 7076, USA
    Am J Physiol Regul Integr Comp Physiol 293:R145-51. 2007
  9. ncbi Pro-inflammatory cytokines and depression in a familial cancer registry
    Mary Frances O'Connor
    Cousins Center for Psychoneuroimmunology, UCLA Semel Institute for Neuroscience and Human Behavior, Los Angeles, CA 90095 7076, USA
    Psychooncology 16:499-501. 2007
  10. ncbi Emotional disclosure for whom? A study of vagal tone in bereavement
    Mary Frances O'Connor
    Department of Psychology, University of Arizona, Tucson, AZ 85721, USA
    Biol Psychol 68:135-46. 2005

Research Grants

Detail Information

Publications20

  1. ncbi Baseline vagal tone predicts BOLD response during elicitation of grief
    Mary Frances O'Connor
    UCLA Neuropsychiatric Institute, Cousins Center for Psychoneuroimmunology, Los Angeles, CA 90095 7076, USA
    Neuropsychopharmacology 32:2184-9. 2007
    ..Future studies should compare differences between central and peripheral arousal in complicated and non-complicated grief...
  2. ncbi Bereavement and the brain: invitation to a conversation between bereavement researchers and neuroscientists
    Mary Frances O'Connor
    Neuropsychiatric Institute, Cousins Center for Psychoneuroimmunology, UCLA, 300 Medical Plaza, Room 3156, Los Angeles, CA 90095 7076, USA
    Death Stud 29:905-22. 2005
    ....
  3. pmc Immunological and neuroimaging biomarkers of complicated grief
    Mary Frances O'Connor
    Cousins Center for Psychoneuroimmunology, Semel Institute for Neuroscience and Human Behavior, University of California at Los Angeles, Los Angeles, CA, USA
    Dialogues Clin Neurosci 14:141-8. 2012
    ..Using theory to point to future research directions, we may eventually learn which biomarkers are helpful in predicting CG, and its treatment...
  4. pmc Diurnal cortisol in Complicated and Non-Complicated Grief: slope differences across the day
    Mary Frances O'Connor
    Cousins Center for Psychoneuroimmunology, UCLA Semel Institute for Neuroscience and Human Behavior, Los Angeles, CA, United States
    Psychoneuroendocrinology 37:725-8. 2012
    ..Results demonstrate that the two groups do not differ on demographic variables (except education), but as hypothesized, those with Complicated Grief have a flatter slope across the day, controlling for education and body mass index...
  5. pmc Links between behavioral factors and inflammation
    M F O'Connor
    Cousins Center for Psychoneuroimmunology, Semel Institute for Neuroscience and Human Behavior, University of California at Los Angeles, Los Angeles, California, USA
    Clin Pharmacol Ther 87:479-82. 2010
    ..Treatment strategies that target biobehavioral factors have the potential to complement and enhance the benefit of anti-inflammatory medicines...
  6. pmc When grief heats up: pro-inflammatory cytokines predict regional brain activation
    Mary Frances O'Connor
    Cousins Center for Psychoneuroimmunology, Semel Institute for Neuroscience and Human Behavior, University of California at Los Angeles, USA
    Neuroimage 47:891-6. 2009
    ..The present study investigated the hypothesis that local inflammation is associated with greater subgenual anterior cingulate cortex (sACC) activation in persons undergoing chronic stress...
  7. pmc Craving love? Enduring grief activates brain's reward center
    Mary Frances O'Connor
    Cousins Center for Psychoneuroimmunology, Semel Institute for Neuroscience and Human Behavior, University of California at Los Angeles, USA
    Neuroimage 42:969-72. 2008
    ..This study supports the hypothesis that attachment activates reward pathways. For those with CG, reminders of the deceased still activate neural reward activity, which may interfere with adapting to the loss in the present...
  8. ncbi Sex differences in monocyte expression of IL-6: role of autonomic mechanisms
    Mary Frances O'Connor
    Cousins Center for Psychoneuroimmunology, UCLA Semel Institute for Neuroscience and Human Behavior, University of California Los Angeles, 300 Medical Plaza, Los Angeles, CA 90095 7076, USA
    Am J Physiol Regul Integr Comp Physiol 293:R145-51. 2007
    ..Interventions that target autonomic mechanisms might constitute new strategies to constrain IL-6 production with impacts on inflammatory disease risk in women...
  9. ncbi Pro-inflammatory cytokines and depression in a familial cancer registry
    Mary Frances O'Connor
    Cousins Center for Psychoneuroimmunology, UCLA Semel Institute for Neuroscience and Human Behavior, Los Angeles, CA 90095 7076, USA
    Psychooncology 16:499-501. 2007
    ..The present data are important for characterizing persons at high risk for cancer who may later acquire knowledge of further increased risk through genetic testing...
  10. ncbi Emotional disclosure for whom? A study of vagal tone in bereavement
    Mary Frances O'Connor
    Department of Psychology, University of Arizona, Tucson, AZ 85721, USA
    Biol Psychol 68:135-46. 2005
    ..Future research should investigate whether vagal tone moderates the impact of written disclosure for non-bereaved individuals...
  11. ncbi Finding boundaries inside prison walls: case study of a terminally ill inmate
    Mary Frances O'Connor
    Neuropsychiatric Institute and Hospital, University of California, Los Angeles, California, USA
    Death Stud 28:63-76. 2004
    ..Creative solutions to these ethical dilemmas were implemented through consideration of the overt and underlying goals of the inmate, the necessary rules and protocols of the prison, and in conjunction with professional codes of ethics...
  12. pmc To assess, to control, to exclude: effects of biobehavioral factors on circulating inflammatory markers
    Mary Frances O'Connor
    Department of Psychiatry and Biobehavioral Sciences, Semel Institute for Neuroscience and Human Behavior, University of California at Los Angeles, Cousins Center for Psychoneuroimmunology, Cousins Center for Psychoneuroimmunology, Los Angeles, CA 90095, USA
    Brain Behav Immun 23:887-97. 2009
    ..These recommendations provide a framework for observational and intervention studies investigating linkages between psychosocial and behavioral factors and inflammation...
  13. ncbi Autonomic and emotion regulation in bereavement and depression
    Mary Frances O'Connor
    Department of Psychology, Building 68, University of Arizona, Tucson 85721, USA
    J Psychosom Res 52:183-5. 2002
    ..Differences include an increase in restlessness, suggesting underlying physiological differences between the groups...
  14. pmc When grief makes you sick: bereavement induced systemic inflammation is a question of genotype
    Christian R Schultze-Florey
    Cousins Center for Psychoneuroimmunology, Semel Institute for Neuroscience and Human Behavior, University of California, Los Angeles, CA 90095, USA
    Brain Behav Immun 26:1066-71. 2012
    ..For these patients, clinical interventions for bereavement-related stressor reduction might be crucial for overall health...
  15. doi Neuropsychological correlates of complicated grief in older spousally bereaved adults
    Mary Frances O'Connor
    Correspondence should be addressed to Mary Frances O Connor, Department of Psychology, University of Arizona, 1503 E University Boulevard, Room 430, Tucson, AZ 85721 E mail
    J Gerontol B Psychol Sci Soc Sci 69:12-8. 2014
    ..We expand on previous research by (a) testing older adults, (b) excluding those with comorbid major depressive disorder, (c) using participant-chosen grief-related stimuli, and (d) using a married, nonbereaved control group...
  16. doi Divergent gene expression responses to Complicated Grief and Non-complicated Grief
    Mary Frances O'Connor
    Department of Psychology, University of Arizona, Tucson, AZ 85750, USA Electronic address
    Brain Behav Immun 37:78-83. 2014
    ..These findings provide a molecular framework for understanding the health effects of bereavement, as well as new insights into the particular gene modules that are most sensitive to the individual's psychological response to loss. ..
  17. pmc Catecholamine predictors of complicated grief treatment outcomes
    Mary Frances O'Connor
    Department of Psychology, University of Arizona, Tucson, AZ 85721, USA
    Int J Psychophysiol 88:349-52. 2013
    ..The present study supports the hypothesis that catecholamine levels are affected by bereavement, and in turn, can affect the ability of those with complicated grief to benefit from psychotherapy...
  18. pmc Smaller cornu ammonis 2-3/dentate gyrus volumes and elevated cortisol in multiple sclerosis patients with depressive symptoms
    Stefan M Gold
    Semel Institute for Neuroscience and Human Behavior, David Geffen School of Medicine at UCLA, Los Angeles, California, USA
    Biol Psychiatry 68:553-9. 2010
    ..We examined the role of subregional hippocampal volume for depression in relapsing-remitting multiple sclerosis...
  19. ncbi Propranolol affects stress-induced leukocytosis and cellular adhesion molecule expression
    E C Kühlwein
    Department of Psychiatry, University of California, San Diego, La Jolla, USA
    Eur J Appl Physiol 86:135-41. 2001
    ..Propranolol affected the cell activation status to a lesser extent, as reflected by the density of adhesion molecules...
  20. ncbi Interleukin-6 and tumor necrosis factor-alpha production after acute psychological stress, exercise, and infused isoproterenol: differential effects and pathways
    M U Goebel
    Department of Psychiatry, University of California, San Diego, La Jolla, USA
    Psychosom Med 62:591-8. 2000
    ....

Research Grants2

  1. Complicated Grief in Older Adults: Physiological Substrates of Emotion Regulation
    MARY FRANCES O CONNOR; Fiscal Year: 2007
    ..Mary-Frances O'Connor, into an independent investigator and allow her to develop an R01 proposal to evaluate treatment for complicated grief, based on both physiological and psychological mechanisms. ..