Research Topics
| Mary Frances O'ConnorSummaryAffiliation: University of California Country: USA Publications
Research Grants
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Detail Information
Publications
Baseline vagal tone predicts BOLD response during elicitation of griefMary Frances O'Connor
UCLA Neuropsychiatric Institute, Cousins Center for Psychoneuroimmunology, Los Angeles, CA 90095 7076, USA
Neuropsychopharmacology 32:2184-9. 2007..Future studies should compare differences between central and peripheral arousal in complicated and non-complicated grief...
Immunological and neuroimaging biomarkers of complicated griefMary Frances O'Connor
Cousins Center for Psychoneuroimmunology, Semel Institute for Neuroscience and Human Behavior, University of California at Los Angeles, Los Angeles, CA, USA
Dialogues Clin Neurosci 14:141-8. 2012..Using theory to point to future research directions, we may eventually learn which biomarkers are helpful in predicting CG, and its treatment...
Diurnal cortisol in Complicated and Non-Complicated Grief: slope differences across the dayMary Frances O'Connor
Cousins Center for Psychoneuroimmunology, UCLA Semel Institute for Neuroscience and Human Behavior, Los Angeles, CA, United States
Psychoneuroendocrinology 37:725-8. 2012..Results demonstrate that the two groups do not differ on demographic variables (except education), but as hypothesized, those with Complicated Grief have a flatter slope across the day, controlling for education and body mass index...
Links between behavioral factors and inflammationM F O'Connor
Cousins Center for Psychoneuroimmunology, Semel Institute for Neuroscience and Human Behavior, University of California at Los Angeles, Los Angeles, California, USA
Clin Pharmacol Ther 87:479-82. 2010..Treatment strategies that target biobehavioral factors have the potential to complement and enhance the benefit of anti-inflammatory medicines...
When grief heats up: pro-inflammatory cytokines predict regional brain activationMary Frances O'Connor
Cousins Center for Psychoneuroimmunology, Semel Institute for Neuroscience and Human Behavior, University of California at Los Angeles, USA
Neuroimage 47:891-6. 2009..The present study investigated the hypothesis that local inflammation is associated with greater subgenual anterior cingulate cortex (sACC) activation in persons undergoing chronic stress...
To assess, to control, to exclude: effects of biobehavioral factors on circulating inflammatory markersMary Frances O'Connor
Department of Psychiatry and Biobehavioral Sciences, Semel Institute for Neuroscience and Human Behavior, University of California at Los Angeles, Cousins Center for Psychoneuroimmunology, Cousins Center for Psychoneuroimmunology, Los Angeles, CA 90095, USA
Brain Behav Immun 23:887-97. 2009..These recommendations provide a framework for observational and intervention studies investigating linkages between psychosocial and behavioral factors and inflammation...
Craving love? Enduring grief activates brain's reward centerMary Frances O'Connor
Cousins Center for Psychoneuroimmunology, Semel Institute for Neuroscience and Human Behavior, University of California at Los Angeles, USA
Neuroimage 42:969-72. 2008..This study supports the hypothesis that attachment activates reward pathways. For those with CG, reminders of the deceased still activate neural reward activity, which may interfere with adapting to the loss in the present...
Sex differences in monocyte expression of IL-6: role of autonomic mechanismsMary Frances O'Connor
Cousins Center for Psychoneuroimmunology, UCLA Semel Institute for Neuroscience and Human Behavior, University of California Los Angeles, 300 Medical Plaza, Los Angeles, CA 90095 7076, USA
Am J Physiol Regul Integr Comp Physiol 293:R145-51. 2007..Interventions that target autonomic mechanisms might constitute new strategies to constrain IL-6 production with impacts on inflammatory disease risk in women...
Pro-inflammatory cytokines and depression in a familial cancer registryMary Frances O'Connor
Cousins Center for Psychoneuroimmunology, UCLA Semel Institute for Neuroscience and Human Behavior, Los Angeles, CA 90095 7076, USA
Psychooncology 16:499-501. 2007..The present data are important for characterizing persons at high risk for cancer who may later acquire knowledge of further increased risk through genetic testing...
Bereavement and the brain: invitation to a conversation between bereavement researchers and neuroscientistsMary Frances O'Connor
Neuropsychiatric Institute, Cousins Center for Psychoneuroimmunology, UCLA, 300 Medical Plaza, Room 3156, Los Angeles, CA 90095 7076, USA
Death Stud 29:905-22. 2005....
Emotional disclosure for whom? A study of vagal tone in bereavementMary Frances O'Connor
Department of Psychology, University of Arizona, Tucson, AZ 85721, USA
Biol Psychol 68:135-46. 2005..Future research should investigate whether vagal tone moderates the impact of written disclosure for non-bereaved individuals...
Finding boundaries inside prison walls: case study of a terminally ill inmateMary Frances O'Connor
Neuropsychiatric Institute and Hospital, University of California, Los Angeles, California, USA
Death Stud 28:63-76. 2004..Creative solutions to these ethical dilemmas were implemented through consideration of the overt and underlying goals of the inmate, the necessary rules and protocols of the prison, and in conjunction with professional codes of ethics...
When grief makes you sick: bereavement induced systemic inflammation is a question of genotypeChristian R Schultze-Florey
Cousins Center for Psychoneuroimmunology, Semel Institute for Neuroscience and Human Behavior, University of California, Los Angeles, CA 90095, USA
Brain Behav Immun 26:1066-71. 2012..For these patients, clinical interventions for bereavement-related stressor reduction might be crucial for overall health...
Smaller cornu ammonis 2-3/dentate gyrus volumes and elevated cortisol in multiple sclerosis patients with depressive symptomsStefan M Gold
Semel Institute for Neuroscience and Human Behavior, David Geffen School of Medicine at UCLA, Los Angeles, California, USA
Biol Psychiatry 68:553-9. 2010..We examined the role of subregional hippocampal volume for depression in relapsing-remitting multiple sclerosis...
Propranolol affects stress-induced leukocytosis and cellular adhesion molecule expressionE C Kühlwein
Department of Psychiatry, University of California, San Diego, La Jolla, USA
Eur J Appl Physiol 86:135-41. 2001..Propranolol affected the cell activation status to a lesser extent, as reflected by the density of adhesion molecules...
Interleukin-6 and tumor necrosis factor-alpha production after acute psychological stress, exercise, and infused isoproterenol: differential effects and pathwaysM U Goebel
Department of Psychiatry, University of California, San Diego, La Jolla, USA
Psychosom Med 62:591-8. 2000....
Research Grants
- Complicated Grief in Older Adults: Physiological Substrates of Emotion RegulationMARY FRANCES O CONNOR; Fiscal Year: 2007..Mary-Frances O'Connor, into an independent investigator and allow her to develop an R01 proposal to evaluate treatment for complicated grief, based on both physiological and psychological mechanisms. ..
