T J O'Brien

Summary

Affiliation: University of Arkansas for Medical Sciences
Country: USA

Publications

  1. ncbi request reprint The CA 125 gene: an extracellular superstructure dominated by repeat sequences
    T J O'Brien
    Department of Obstetrics and Gynecology, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA
    Tumour Biol 22:348-66. 2001
  2. ncbi request reprint Ovarian tumor cells express a novel multi-domain cell surface serine protease
    L J Underwood
    Department of Biochemistry and Molecular Biology, University of Arkansas for Medical Sciences, Little Rock, AR 72205 7199, USA
    Biochim Biophys Acta 1502:337-50. 2000
  3. ncbi request reprint Novel immunotherapeutic strategies in gynecologic oncology. Dendritic cell-based immunotherapy for ovarian cancer
    A D Santin
    Department of Otolaryngology, University of Arkansas for Medical Sciences, USA
    Minerva Ginecol 54:133-44. 2002
  4. pmc Discrimination between uterine serous papillary carcinomas and ovarian serous papillary tumours by gene expression profiling
    A D Santin
    Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, University of Arkansas for Medical Sciences, UAMS Medical Center, 4301 West Markham, Little Rock, AR 72205 7199, USA
    Br J Cancer 90:1814-24. 2004
  5. ncbi request reprint Cloning of tumor-associated differentially expressed gene-14, a novel serine protease overexpressed by ovarian carcinoma
    L J Underwood
    Department of Obstetrics, University of Arkansas for Medical Sciences, Little Rock 72205 7199, USA
    Cancer Res 59:4435-9. 1999

Collaborators

Detail Information

Publications5

  1. ncbi request reprint The CA 125 gene: an extracellular superstructure dominated by repeat sequences
    T J O'Brien
    Department of Obstetrics and Gynecology, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA
    Tumour Biol 22:348-66. 2001
    ..Sequencing the gene provides us with the ability to initiate the quest to understand the biological function of CA 125...
  2. ncbi request reprint Ovarian tumor cells express a novel multi-domain cell surface serine protease
    L J Underwood
    Department of Biochemistry and Molecular Biology, University of Arkansas for Medical Sciences, Little Rock, AR 72205 7199, USA
    Biochim Biophys Acta 1502:337-50. 2000
    ..These features imply that TADG-12 will be at the cell surface, and it may be useful as a molecular target for therapy or a diagnostic marker...
  3. ncbi request reprint Novel immunotherapeutic strategies in gynecologic oncology. Dendritic cell-based immunotherapy for ovarian cancer
    A D Santin
    Department of Otolaryngology, University of Arkansas for Medical Sciences, USA
    Minerva Ginecol 54:133-44. 2002
    ..In this review, we describe these ovarian tumor antigens and assess the potential for therapeutic DC vaccination for the treatment of chemotherapy-resistant ovarian cancer...
  4. pmc Discrimination between uterine serous papillary carcinomas and ovarian serous papillary tumours by gene expression profiling
    A D Santin
    Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, University of Arkansas for Medical Sciences, UAMS Medical Center, 4301 West Markham, Little Rock, AR 72205 7199, USA
    Br J Cancer 90:1814-24. 2004
    ..A therapeutic strategy targeting HER-2/neu may be beneficial in patients harbouring chemotherapy-resistant USPC...
  5. ncbi request reprint Cloning of tumor-associated differentially expressed gene-14, a novel serine protease overexpressed by ovarian carcinoma
    L J Underwood
    Department of Obstetrics, University of Arkansas for Medical Sciences, Little Rock 72205 7199, USA
    Cancer Res 59:4435-9. 1999
    ..Northern blot data confirm this overexpression, and immunohistochemical staining suggests that this protein is secreted. As such, the TADG14 protease may be useful as a diagnostic tool or as a molecular target for therapy...