John M O'Brien
Affiliation: University of Kentucky
- Augmenting myometrial healing after cesarean delivery: use of an adjuvant biologic graft placement in an ovine modelJohn M O'Brien
Maternal Fetal Medicine, University of Kentucky, 800 Rose Street, Lexington, KY 40536, USA
Am J Perinatol 28:543-50. 2011..Myometrial repair incorporating a graft increased scar thickness and neoangiogenesis. This methodology did not incite adenomyosis or enhance inflammation within the scar...
- The safety of progesterone and 17-hydroxyprogesterone caproate administration for the prevention of preterm birth: an evidence-based assessmentJohn M O'Brien
Division of Maternal Fetal Medicine, Department of Obstetrics and Gynecology, University of Kentucky, Lexington, Kentucky, USA
Am J Perinatol 29:665-72. 2012..Further data are needed interrogating the potential for rare fetal or maternal adverse events/safety outcomes with exposure to progestins. Safety concerns should be incorporated into prescribing decisions...
- Uterine activity in women receiving 17 alpha-hydroxyprogesterone caproate for the prevention of preterm birth: an observational studyJohn M O'Brien
Perinatal Diagnostic Center, Central Baptist Hospital, 1740 Nicholasville Road, Lexington, KY 40502, USA
Am J Perinatol 27:157-62. 2010..Although a statistically significant increase in contractions was identified posttherapy versus pretherapy, the clinical importance of this observation is unknown...
- Progestins for the prevention of spontaneous preterm birth: review and implications of recent studiesJohn M O'Brien
Perinatal Diagnostic Center, Central Baptist Hospital, Lexington, Kentucky 40503, USA
J Reprod Med 54:73-87. 2009..This review presents recent findings regarding progestin therapy from both clinical and laboratory data and considers unresolved issues for use of these agents...
- Does an obese prepregnancy body mass index influence outcome in pregnancies complicated by mild gestational hypertension remote from term?David G Lombardi
Department of Obstetrics and Gynecology, University of Kentucky, Lexington, USA
Am J Obstet Gynecol 192:1472-4. 2005..This study was undertaken to determine the influence of increased prepregnancy body mass index (BMI) on pregnancy outcome in women with mild gestational hypertension remote from term...