Research Topics
Genomes and GenesSpecies | Rebecca NuzzoSummaryAffiliation: University of Texas Southwestern Medical Center Country: USA Publications
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Publications
Abciximab and early adjunctive percutaneous coronary intervention are associated with improved ST-segment resolution after thrombolysis: Observations from the TIMI 14 TrialJ A de Lemos
Donald W Reynolds Cardiovascular Clinical Research Center, The University of Texas Southwestern Medical Center at Dallas, 5323 Harry Hines Blvd, Room 8 116, Dallas, TX 75390 9034, USA
Am Heart J 141:592-8. 2001....- Association of troponin T detected with a highly sensitive assay and cardiac structure and mortality risk in the general populationJames A de Lemos
Division of Cardiology, University of Texas Southwestern Medical Center, 5909 Harry Hines Blvd, Dallas, TX 75390 9047, USA
JAMA 304:2503-12. 2010.... - Screening the population for left ventricular hypertrophy and left ventricular systolic dysfunction using natriuretic peptides: results from the Dallas Heart StudyJames A de Lemos
Donald W Reynolds Cardiovascular Research Center, UT Southwestern Medical Center, Dallas, TX 75390 9047, USA
Am Heart J 157:746-53.e2. 2009..We performed a comprehensive evaluation of the screening performance of B-type natriuretic peptide (BNP) and N-terminal pro-BNP (NT-proBNP) for LVSD or LVH... - Amino-terminal pro-B-type natriuretic peptides: testing in general populationsJames A de Lemos
Cardiology Division, University of Texas, Southwestern Medical Center, Dallas, TX 75390 9047, USA
Am J Cardiol 101:16-20. 2008..Better understanding of these factors may allow optimization of thresholds for screening of apparently well patients and concomitant delineation of patient populations in whom NT-proBNP screening is less appropriate... - Serial measurement of monocyte chemoattractant protein-1 after acute coronary syndromes: results from the A to Z trialJames A de Lemos
Donald W Reynolds Cardiovascular Clinical Research Center, UT Southwestern Medical Center, Dallas, Texas 75390 9047, USA
J Am Coll Cardiol 50:2117-24. 2007..This study sought to determine whether the novel biomarker monocyte chemoattractant protein (MCP)-1 adds prognostic value to standard risk assessment tools and biomarkers after acute coronary syndromes (ACS)... - Current status of risk stratification methods in acute coronary syndromesRaphael See
Cardiology Division, UT Southwestern Medical Center, 5909 Harry Hines Boulevard, HA 9 133, Dallas, TX 75390 9047, USA
Curr Cardiol Rep 8:282-8. 2006..Finally, advances in coronary CT angiography and bedside echocardiography offer hope that noninvasive imaging may play a more important role in early risk stratification in the near future... - Associations between soluble CD40 ligand, atherosclerosis risk factors, and subclinical atherosclerosis: results from the Dallas Heart StudyJames A de Lemos
Donald W Reynolds Cardiovascular Clinical Research Center, University of Texas Southwestern Medical Center, Dallas, TX, USA
Arterioscler Thromb Vasc Biol 25:2192-6. 2005..The purpose of this study was to evaluate the associations between plasma levels of soluble CD40 ligand (sCD40L), atherosclerosis risk factors, and evidence of subclinical atherosclerosis... - Enoxaparin versus unfractionated heparin in patients treated with tirofiban, aspirin and an early conservative initial management strategy: results from the A phase of the A-to-Z trialJames A de Lemos
Donald W Reynolds Cardiovascular Clinical Research Center, 5323 Harry Hines Blvd, Rm HA 9 133, UT Southwestern Medical Center, Dallas, TX 75390 9047, USA
Eur Heart J 25:1688-94. 2004..However, less is known about the relative merits of these two forms of heparin in patients receiving concomitant glycoprotein IIb/IIIa inhibitors... - Early intensive vs a delayed conservative simvastatin strategy in patients with acute coronary syndromes: phase Z of the A to Z trialJames A de Lemos
Donald W Reynolds Cardiovascular Clinical Research Center, The University of Texas Southwestern Medical Center, Dallas 75390 9047, USA
JAMA 292:1307-16. 2004..Limited data are available evaluating how the timing and intensity of statin therapy following an acute coronary syndrome (ACS) event affect clinical outcome... - B-type natriuretic peptide in cardiovascular diseaseJames A de Lemos
Donald W Reynolds Cardiovascular Clinical Research Center and Department of Medicine, University of Texas Southwestern Medical Center, Dallas, TX 75390 9047, USA
Lancet 362:316-22. 2003.... - B-type natriuretic peptide in ischemic heart diseaseRajat Deo
Division of Cardiology, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, HA 9 133, Dallas, TX 75390 9047, USA
Curr Cardiol Rep 5:271-7. 2003..Future studies are needed to identify the therapeutic implications of BNP elevation in patients with ACS... - Early noninvasive detection of failed epicardial reperfusion after fibrinolytic therapyJ A de Lemos
Donald W Reynolds Cardiovascular Clinical Research Center and the University of Texas Southwestern Medical Center, Dallas, Texas 75390 9034, USA
Am J Cardiol 88:353-8. 2001..In conclusion, ST-segment resolution, chest pain resolution, and early washout of serum myoglobin can be used in combination to aid in the early noninvasive identification of candidates for rescue percutaneous coronary intervention... - The prognostic value of B-type natriuretic peptide in patients with acute coronary syndromesJ A de Lemos
Thrombolysis in Myocardial Infarction Study Group, Boston, USA
N Engl J Med 345:1014-21. 2001.... - Association between plasma levels of monocyte chemoattractant protein-1 and long-term clinical outcomes in patients with acute coronary syndromesJames A de Lemos
TIMI Study Group, Donald W Reynolds Cardiovascular Clinical Research Center, The University of Texas, Southwestern Medical School, Dallas, TX 75390 9047, USA
Circulation 107:690-5. 2003..MCP-1 appears to play a critical role at multiple stages in atherosclerosis, including the initiation of the fatty streak, promotion of plaque instability, and remodeling after myocardial infarction... - ST segment resolution as a tool for assessing the efficacy of reperfusion therapyJ A de Lemos
Donald W Reynolds Cardiovascular Clinical Research Center, University of Texas Southwestern Medical Center, Dallas, Texas 75093 9034, USA
J Am Coll Cardiol 38:1283-94. 2001.... - The prognostic value of serum myoglobin in patients with non-ST-segment elevation acute coronary syndromes. Results from the TIMI 11B and TACTICS-TIMI 18 studiesJames A de Lemos
Thrombolysis in Myocardial Infarction TIMI Study Group, Reynolds Cardiovascular Clinical Research Center, University of Texas Southwestern Medical School, 5323 Harry Hines Boulevard, Dallas, TX 75390 9047, USA
J Am Coll Cardiol 40:238-44. 2002..The goal of this study was to define the prognostic value of serum myoglobin in patients with non-ST-elevation acute coronary syndromes (ACS)... - Soluble CD40L: risk prediction after acute coronary syndromesNerea Varo
Donald W. Reynolds Cardiovascular Clinical Research Center, Brigham and Women's Hospital, Harvard Medical School, Boston, Mass 02115, USA
Circulation 108:1049-52. 2003..Notably, combined assessment of sCD40L with cTnI complements prognostic information for death and MI... - Influence of pre-analytical and analytical factors on soluble CD40L measurementsNerea Varo
Donald W. Reynolds Cardiovascular Clinical Research Center, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, 77 Avenue Louis Pasteur, NRB 741, Boston, MA 02115, USA
Clin Sci (Lond) 111:341-7. 2006..Samples with high concentrations of bilirubin, haemoglobin and/or triacylglycerols should be excluded, as these substances interfere with the assay... - Elevated release of sCD40L from platelets of diabetic patients by thrombin, glucose and advanced glycation end productsNerea Varo
Donald W Reynolds Cardiovascular Clinical Research Center, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA
Diab Vasc Dis Res 2:81-7. 2005.... - Elevated plasma levels of the atherogenic mediator soluble CD40 ligand in diabetic patients: a novel target of thiazolidinedionesNerea Varo
Cardiovascular Medicine, Brigham and Women s Hospital, Harvard Medical School, 221 Longwood Ave, Boston, Mass 02115, USA
Circulation 107:2664-9. 2003..This study therefore evaluated the hypothesis that diabetic patients have elevated plasma levels of soluble CD40L (sCD40L) and that treatment with the insulin-sensitizing thiazolidinediones lowers this index of inflammation... - Interactions between smoking, pulmonary surfactant protein B, and atherosclerosis in the general population: the Dallas Heart StudyAnn B Nguyen
Division of Cardiology, University of Texas Southwestern Medical Center, Dallas, TX 75390 9047, USA
Arterioscler Thromb Vasc Biol 31:2136-43. 2011..We hypothesized that SP-B may serve as a marker of the vascular effects of smoking and would thus be associated with subclinical measures of atherosclerosis...