Klaus Nusslein

Summary

Affiliation: University of Massachusetts
Country: USA

Publications

  1. pmc Desiccation induces viable but Non-Culturable cells in Sinorhizobium meliloti 1021
    Jan Ac Vriezen
    Department of Microbiology, University of Massachusetts, Amherst, Massachusetts, USA, MA 01003
    AMB Express 2:6. 2012
  2. ncbi request reprint Broad-spectrum antibacterial activity by a novel abiogenic peptide mimic
    Klaus Nusslein
    Department of Microbiology, University of Massachusetts, Amherst, 01003, USA
    Microbiology 152:1913-8. 2006
  3. doi request reprint Investigating the effect of increasing charge density on the hemolytic activity of synthetic antimicrobial polymers
    Zoha M Al-Badri
    Department of Polymer Science and Engineering, University of Massachusetts Amherst, Amherst, Massachusetts 01003, USA
    Biomacromolecules 9:2805-10. 2008
  4. doi request reprint Antimicrobial polymers prepared by ring-opening metathesis polymerization: manipulating antimicrobial properties by organic counterion and charge density variation
    Karen Lienkamp
    Department of Polymer Science and Engineering, University of Massachusetts, Amherst, MA 01003, USA
    Chemistry 15:11715-22. 2009
  5. pmc Synthetic mimic of antimicrobial peptide with nonmembrane-disrupting antibacterial properties
    Gregory J Gabriel
    Department of Polymer Science and Engineering, University of Massachusetts Amherst, Amherst, Massachusetts 01003, USA
    Biomacromolecules 9:2980-3. 2008
  6. doi request reprint "Doubly selective" antimicrobial polymers: how do they differentiate between bacteria?
    Karen Lienkamp
    Department of Polymer Science and Engineering, University of Massachusetts, Amherst, MA 01003, USA
    Chemistry 15:11710-4. 2009
  7. doi request reprint Using flow to switch the valency of bacterial capture on engineered surfaces containing immobilized nanoparticles
    Bing Fang
    Department of Polymer Science and Engineering, University of Massachusetts, Amherst, Massachusetts 01003, USA
    Langmuir 28:7803-10. 2012
  8. doi request reprint Hydrophilic modifications of an amphiphilic polynorbornene and the effects on its hemolytic and antibacterial activity
    Semra Colak
    Department of Polymer Science and Engineering, University of Massachusetts Amherst, 120 Governors Drive, Amherst, Massachusetts 01003, USA
    Biomacromolecules 10:353-9. 2009
  9. doi request reprint Bacterial adhesion on hybrid cationic nanoparticle-polymer brush surfaces: ionic strength tunes capture from monovalent to multivalent binding
    Bing Fang
    Department of Polymer Science and Engineering, University of Massachusetts at Amherst, Amherst, MA 01003, USA
    Colloids Surf B Biointerfaces 87:109-15. 2011
  10. doi request reprint Comparison of facially amphiphilic versus segregated monomers in the design of antibacterial copolymers
    Gregory J Gabriel
    Department of Polymer Science and Engineering, University of Massachusetts, Amherst, MA 01003, USA
    Chemistry 15:433-9. 2009

Collaborators

  • Gregory N Tew
  • Chul Park
  • Yan Li
  • Richard W Scott
  • Lisa M Stout
  • Gary M King
  • Brian P Gibney
  • Karen Lienkamp
  • Ahmad E Madkour
  • Christopher F Nelson
  • Bing Fang
  • Kushi Nidhi Kumar
  • Gregory J Gabriel
  • Maria M Santore
  • Jan Ac Vriezen
  • Kyunghwa Baek
  • Vincent M Rotello
  • Saugata Gon
  • Surachate Kalasin
  • Semra Colak
  • Abhigyan Som
  • Jeffrey M Dabkowski
  • Zoha M Al-Badri
  • Patricia J Waldron
  • Vicente Gomez-Alvarez
  • Javier A Izquierdo
  • Sarina J Ergas
  • Frans J de Bruijn
  • Robert McKeever
  • Diane Sheppard
  • Kahlil Rieber
  • Myoung Hwan Park
  • Myoung Park
  • Jeffrey Dabkowski
  • Janet A Maegerlein
  • Tarik Eren
  • Jeffery M Dabkowski
  • Ashlan Musante
  • Sarah Lyon
  • Klaus Nüslein
  • Steven T Petsch
  • Anna M Martini

Detail Information

Publications21

  1. pmc Desiccation induces viable but Non-Culturable cells in Sinorhizobium meliloti 1021
    Jan Ac Vriezen
    Department of Microbiology, University of Massachusetts, Amherst, Massachusetts, USA, MA 01003
    AMB Express 2:6. 2012
    ..This observation has important consequences for the use of rhizobia. Finding methods to resuscitate this fraction may increase the quality of powder-based seed inocula...
  2. ncbi request reprint Broad-spectrum antibacterial activity by a novel abiogenic peptide mimic
    Klaus Nusslein
    Department of Microbiology, University of Massachusetts, Amherst, 01003, USA
    Microbiology 152:1913-8. 2006
    ....
  3. doi request reprint Investigating the effect of increasing charge density on the hemolytic activity of synthetic antimicrobial polymers
    Zoha M Al-Badri
    Department of Polymer Science and Engineering, University of Massachusetts Amherst, Amherst, Massachusetts 01003, USA
    Biomacromolecules 9:2805-10. 2008
    ..To understand the membrane activity of these polymers, we conducted dye leakage experiments on lipid vesicles that mimic bacteria and red blood cell membranes, and these results showed a strong correlation with the hemolysis data...
  4. doi request reprint Antimicrobial polymers prepared by ring-opening metathesis polymerization: manipulating antimicrobial properties by organic counterion and charge density variation
    Karen Lienkamp
    Department of Polymer Science and Engineering, University of Massachusetts, Amherst, MA 01003, USA
    Chemistry 15:11715-22. 2009
    ..A SMAMP with an MIC90 of 4 microg mL(-1) against Staphylococcus aureus and a selectivity (=HC50/MIC90) of 650 was discovered, the most selective SMAMP to date...
  5. pmc Synthetic mimic of antimicrobial peptide with nonmembrane-disrupting antibacterial properties
    Gregory J Gabriel
    Department of Polymer Science and Engineering, University of Massachusetts Amherst, Amherst, Massachusetts 01003, USA
    Biomacromolecules 9:2980-3. 2008
    ..The unique biological properties of PGON, in same ways similar to cell-penetrating peptides, strongly encourage the examination of other novel guanidino containing macromolecules as powerful and selective antimicrobial agents...
  6. doi request reprint "Doubly selective" antimicrobial polymers: how do they differentiate between bacteria?
    Karen Lienkamp
    Department of Polymer Science and Engineering, University of Massachusetts, Amherst, MA 01003, USA
    Chemistry 15:11710-4. 2009
    ..aureus bacteria, the 50000 g mol(-1) SMAMP got stuck and consequently did not have antimicrobial activity...
  7. doi request reprint Using flow to switch the valency of bacterial capture on engineered surfaces containing immobilized nanoparticles
    Bing Fang
    Department of Polymer Science and Engineering, University of Massachusetts, Amherst, Massachusetts 01003, USA
    Langmuir 28:7803-10. 2012
    ..These finding suggest the use of surface elements to manipulate individual bacteria and nonfouling designs with precise but finite bacterial interactions...
  8. doi request reprint Hydrophilic modifications of an amphiphilic polynorbornene and the effects on its hemolytic and antibacterial activity
    Semra Colak
    Department of Polymer Science and Engineering, University of Massachusetts Amherst, 120 Governors Drive, Amherst, Massachusetts 01003, USA
    Biomacromolecules 10:353-9. 2009
    ..08 to 1.15 were obtained. The effects of these modifications on the biological activity of these polymers were analyzed by determining their minimum inhibitory concentrations (MIC) and their hemolytic activities (HC50)...
  9. doi request reprint Bacterial adhesion on hybrid cationic nanoparticle-polymer brush surfaces: ionic strength tunes capture from monovalent to multivalent binding
    Bing Fang
    Department of Polymer Science and Engineering, University of Massachusetts at Amherst, Amherst, MA 01003, USA
    Colloids Surf B Biointerfaces 87:109-15. 2011
    ..Thus brushy relaxations increase biocompatibility...
  10. doi request reprint Comparison of facially amphiphilic versus segregated monomers in the design of antibacterial copolymers
    Gregory J Gabriel
    Department of Polymer Science and Engineering, University of Massachusetts, Amherst, MA 01003, USA
    Chemistry 15:433-9. 2009
    ..We advocate the use of FA monomers for better control of biological properties. It is expected that this principle will be usefully applied to other backbones such as the polyacrylates, polystyrenes, and non-natural polyamides...
  11. pmc Fast disinfecting antimicrobial surfaces
    Ahmad E Madkour
    Department of Polymer Science and Engineering, University of Massachusetts, Amherst, Massachusetts 01003, USA
    Langmuir 25:1060-7. 2009
    ..Antimicrobial studies showed that the killing efficiency of these surfaces was independent of polymer layer thickness or grafting density within the range of surfaces studied...
  12. doi request reprint New bactericidal surgical suture coating
    Yan Li
    Department of Polymer Science and Engineering, University of Massachusetts, Amherst, Amherst, Massachusetts 01003, United States
    Langmuir 28:12134-9. 2012
    ..The PAMBM-containing sutures killed bacteria more effectively (3 log(10) reduction at 2.4 wt %) than Vicryl Plus sutures (0.5 log(10) reduction)...
  13. pmc Shifts in rhizoplane communities of aquatic plants after cadmium exposure
    Lisa M Stout
    Department of Microbiology, University of Massachusetts, Amherst, MA 01003 9298, USA
    Appl Environ Microbiol 71:2484-92. 2005
    ..This study is a first step in understanding the role of aquatic plant-associated microbial communities in phytoremediation of heavy metals...
  14. ncbi request reprint Arsenic sequestration by nitrate respiring microbial communities in urban lake sediments
    Brian P Gibney
    Department of Microbiology, University of Massachusetts, Amherst, MA 01003, USA
    Chemosphere 70:329-36. 2007
    ....
  15. pmc Salinity constraints on subsurface archaeal diversity and methanogenesis in sedimentary rock rich in organic matter
    Patricia J Waldron
    Department of Microbiology, University of Massachusetts, Amherst, MA 01003, USA
    Appl Environ Microbiol 73:4171-9. 2007
    ....
  16. ncbi request reprint Comparative bacterial diversity in recent Hawaiian volcanic deposits of different ages
    Vicente Gomez-Alvarez
    Department of Microbiology, University of Massachusetts, Amherst, MA 01003, USA
    FEMS Microbiol Ecol 60:60-73. 2007
    ..This study not only showed that microorganisms colonize recent volcanic deposits and are able to establish diverse communities, but also that their composition is governed by variations in local deposit parameters...
  17. ncbi request reprint Distribution of extensive nifH gene diversity across physical soil microenvironments
    Javier A Izquierdo
    Department of Microbiology, University of Massachusetts, Amherst, MA, USA
    Microb Ecol 51:441-52. 2006
    ..This study not only provides new knowledge of the arrangement of diazotrophic communities at the soil microscale, but it also contributes to the underrepresented knowledge of soil nifH sequences in the public databases...
  18. doi request reprint The role of nano-scale heterogeneous electrostatic interactions in initial bacterial adhesion from flow: a case study with Staphylococcus aureus
    Surachate Kalasin
    Department of Physics, University of Massachusetts, Amherst, MA 01003, United States
    Colloids Surf B Biointerfaces 76:489-95. 2010
    ..The study further revealed a hydrodynamic crossover from a regime where flow aids bacterial adhesion to one where flow impedes adhesion. An explanation is put forth in terms of the relative hydrodynamic and surface forces...
  19. doi request reprint Molecular approach to evaluate biostimulation of 1,2-dibromoethane in contaminated groundwater
    Kyunghwa Baek
    Department of Microbiology, University of Massachusetts, Amherst, MA 01003, USA
    Bioresour Technol 123:207-13. 2012
    ..This is also reflected in the history of the plume, which originated from an aviation gasoline pipeline leak. This study suggests that biostimulation of EDB is possible at aerobic groundwater sites...
  20. doi request reprint Antimicrobial polymers prepared by ROMP with unprecedented selectivity: a molecular construction kit approach
    Karen Lienkamp
    Department of Polymer Science and Engineering, University of Massachusetts, Amherst, Massachusetts 01003, USA
    J Am Chem Soc 130:9836-43. 2008
    ..This kind of "double selectivity" (bacteria over mammalian and one bacterial type over another) is unprecedented in other polymer systems and is attributed to the monomer's facial amphiphilicity...
  21. doi request reprint Phytoprotective influence of bacteria on growth and cadmium accumulation in the aquatic plant Lemna minor
    Lisa M Stout
    Department of Microbiology, University of Massachusetts, Amherst, MA 01003 9298, USA
    Water Res 44:4970-9. 2010
    ..This suggests that bacteria serve a phytoprotective role in their relationship with Lemna minor, preventing toxic cadmium from entering plants...