- Combination flucytosine and high-dose fluconazole compared with fluconazole monotherapy for the treatment of cryptococcal meningitis: a randomized trial in MalawiJesse C Nussbaum
University of North Carolina UNC Project and 2Kamuzu Central Hospital, Lilongwe, Malawi
Clin Infect Dis 50:338-44. 2010..Fluconazole at a dosage of 1200 mg per day is more fungicidal than at a dosage of 800 mg per day, but mortality rates remain unacceptably high. Therefore, we examined the effect of adding oral flucytosine to fluconazole...
- A phase II randomized controlled trial adding oral flucytosine to high-dose fluconazole, with short-course amphotericin B, for cryptococcal meningitisArthur T Jackson
University of North Carolina Project, Lilongwe, Malawi
AIDS 26:1363-70. 2012..We examined strategies to improve on fluconazole (FLU) monotherapy: addition of flucytosine (5-FC) and/or addition of short-course amphotericin B (AmB)...