Marek Nowicki

Summary

Affiliation: University of Southern California
Country: USA

Publications

  1. pmc Longitudinal variability of human immunodeficiency virus type 1 RNA viral load measurements by nucleic acid sequence-based amplification and NucliSens assays in a large multicenter study
    M J Nowicki
    University of Southern California, Pediatrics, Los Angeles, California 90033, USA
    J Clin Microbiol 39:3760-3. 2001
  2. ncbi request reprint Differential display analysis of gene expression in brains from hepatitis C-infected patients
    Debra M Adair
    Department of Medicine, Mayo Clinic Scottsdale, Scottsdale, AZ, USA
    AIDS 19:S145-50. 2005
  3. pmc Genital herpes evaluation by quantitative TaqMan PCR: correlating single detection and quantity of HSV-2 DNA in cervicovaginal lavage fluids with cross-sectional and longitudinal clinical data
    Bulbulgul Aumakhan
    Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA
    Virol J 7:328. 2010
  4. pmc Presence of hepatitis C virus (HCV) RNA in the genital tracts of HCV/HIV-1-coinfected women
    Marek J Nowicki
    Maternal Child and Adolescent Center for Infectious Diseases and Virology, University of Southern California, Los Angeles 90033, and Mayo Clinic, Scottsdale, USA
    J Infect Dis 192:1557-65. 2005
  5. ncbi request reprint High seroprevalence of anti-HTLV-I/II antibodies among solid organ donors necessitates confirmatory testing
    Marek J Nowicki
    National Institute of Transplantation, Los Angeles, CA 90057, USA
    Transplantation 82:1210-3. 2006
  6. ncbi request reprint Correlates of CD4+ and CD8+ lymphocyte counts in high-risk immunodeficiency virus (HIV)-seronegative women enrolled in the women's interagency HIV study (WIHS)
    Marek J Nowicki
    Department of Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California 90033, USA
    Hum Immunol 68:342-9. 2007
  7. doi request reprint Association of cells with natural killer (NK) and NKT immunophenotype with incident cancers in HIV-infected women
    Marek J Nowicki
    Keck School of Medicine, University of Southern California, Los Angeles, California 90033, USA
    AIDS Res Hum Retroviruses 24:163-8. 2008
  8. pmc Lower liver-related death in African-American women with human immunodeficiency virus/hepatitis C virus coinfection, compared to Caucasian and Hispanic women
    Monika Sarkar
    Department of Medicine, University of California, San Francisco, CA, USA
    Hepatology 56:1699-705. 2012
  9. ncbi request reprint Human immunodeficiency virus facilitates infection/replication of hepatitis C virus in native human macrophages
    Tomasz Laskus
    Department of Medicine, Mayo Clinic Scottsdale, AZ 85259, USA
    Blood 103:3854-9. 2004
  10. ncbi request reprint Persistence of hepatitis C virus in patients successfully treated for chronic hepatitis C
    Marek Radkowski
    Department of Medicine, Mayo Clinic Scottsdale, Scottsdale, AZ 85259, USA
    Hepatology 41:106-14. 2005

Collaborators

Detail Information

Publications32

  1. pmc Longitudinal variability of human immunodeficiency virus type 1 RNA viral load measurements by nucleic acid sequence-based amplification and NucliSens assays in a large multicenter study
    M J Nowicki
    University of Southern California, Pediatrics, Los Angeles, California 90033, USA
    J Clin Microbiol 39:3760-3. 2001
    ..Results indicate that HIV-1 RNA levels can be measured with a precision equal to that of the pre-highly active antiretroviral therapy era (standard deviations, +/-0.16 to 0.25 log10 units)...
  2. ncbi request reprint Differential display analysis of gene expression in brains from hepatitis C-infected patients
    Debra M Adair
    Department of Medicine, Mayo Clinic Scottsdale, Scottsdale, AZ, USA
    AIDS 19:S145-50. 2005
    ..Hepatitis C virus (HCV) infection is often associated with cognitive dysfunction, fatigue and depression. The current study was undertaken to determine whether HCV infection affects gene expression in brain tissue...
  3. pmc Genital herpes evaluation by quantitative TaqMan PCR: correlating single detection and quantity of HSV-2 DNA in cervicovaginal lavage fluids with cross-sectional and longitudinal clinical data
    Bulbulgul Aumakhan
    Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA
    Virol J 7:328. 2010
    ....
  4. pmc Presence of hepatitis C virus (HCV) RNA in the genital tracts of HCV/HIV-1-coinfected women
    Marek J Nowicki
    Maternal Child and Adolescent Center for Infectious Diseases and Virology, University of Southern California, Los Angeles 90033, and Mayo Clinic, Scottsdale, USA
    J Infect Dis 192:1557-65. 2005
    ..Hepatitis C virus (HCV)-infected women--in particular, those coinfected with human immunodeficiency virus type 1 (HIV-1)--can transmit infection to their children and sex partners...
  5. ncbi request reprint High seroprevalence of anti-HTLV-I/II antibodies among solid organ donors necessitates confirmatory testing
    Marek J Nowicki
    National Institute of Transplantation, Los Angeles, CA 90057, USA
    Transplantation 82:1210-3. 2006
    ..Confirmatory testing is not routinely performed, and the number of false positive organ donors is unknown...
  6. ncbi request reprint Correlates of CD4+ and CD8+ lymphocyte counts in high-risk immunodeficiency virus (HIV)-seronegative women enrolled in the women's interagency HIV study (WIHS)
    Marek J Nowicki
    Department of Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California 90033, USA
    Hum Immunol 68:342-9. 2007
    ..Multiple demographic and behavioral factors may influence CD4 and CD8 counts in HIV negative women. These factors must be considered in future analyses comparing lymphocyte subsets in HIV positive and negative women...
  7. doi request reprint Association of cells with natural killer (NK) and NKT immunophenotype with incident cancers in HIV-infected women
    Marek J Nowicki
    Keck School of Medicine, University of Southern California, Los Angeles, California 90033, USA
    AIDS Res Hum Retroviruses 24:163-8. 2008
    ..HIV-induced innate immune dysfunction may contribute to the eventual emergence of cancer in the setting of existing coinfections and altered immunosurveillance...
  8. pmc Lower liver-related death in African-American women with human immunodeficiency virus/hepatitis C virus coinfection, compared to Caucasian and Hispanic women
    Monika Sarkar
    Department of Medicine, University of California, San Francisco, CA, USA
    Hepatology 56:1699-705. 2012
    ..19-0.88; P = 0.022) and Hispanic coinfected women (HR, 0.38; 95% CI: 0.19-0.76; P = 0.006). All-cause mortality was similar between racial/ethnic groups (HRs for all comparisons: 0.82-1.03; log-rank test: P = 0.8)...
  9. ncbi request reprint Human immunodeficiency virus facilitates infection/replication of hepatitis C virus in native human macrophages
    Tomasz Laskus
    Department of Medicine, Mayo Clinic Scottsdale, AZ 85259, USA
    Blood 103:3854-9. 2004
    ..This could explain the presence of extrahepatic HCV replication in HIV-coinfected individuals...
  10. ncbi request reprint Persistence of hepatitis C virus in patients successfully treated for chronic hepatitis C
    Marek Radkowski
    Department of Medicine, Mayo Clinic Scottsdale, Scottsdale, AZ 85259, USA
    Hepatology 41:106-14. 2005
    ..This continuous viral presence could result in persistence of humoral and cellular immunity for many years after therapy and could present a potential risk for infection reactivation...
  11. pmc Comparisons of creatinine and cystatin C for detection of kidney disease and prediction of all-cause mortality in HIV-infected women
    Todd H Driver
    aSchool of Medicine bDepartment of Medicine cDepartment of Epidemiology and Biostatistics, San Francisco Veterans Affairs Medical Center, University of California, San Francisco, California dDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland eSection of Nephrology, Department of Medicine fProgram of Applied Translational Research, Yale University, New Haven, Connecticut gClinical Immunology Research Laboratory, University of California, Los Angeles, California hDepartments of Medicine and of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, New York iDepartments of Medicine, Stroger Hospital and Rush University, Chicago, Illinois jUniversity of Southern California, Los Angeles, California kDivision of Infectious Diseases, Department of Medicine, SUNY Downstate Medical Center, Brooklyn, New York lGeorgetown University Medical Center, Washington, DC, USA
    AIDS 27:2291-9. 2013
    ..Cystatin C could improve chronic kidney disease (CKD) classification in HIV-infected women relative to serum creatinine...
  12. ncbi request reprint Emerging evidence of hepatitis C virus neuroinvasion
    Tomasz Laskus
    Department of Medicine, Mayo Clinic Scottsdale, Scottsdale, Arizona 85259, USA
    AIDS 19:S140-4. 2005
    ..However, despite some similarities there is a fundamental difference between HIV-1 and HCV infection as the latter does not progress into AIDS-type dementia...
  13. ncbi request reprint The origin of hepatitis C virus reinfecting transplanted livers: serum-derived versus peripheral blood mononuclear cell-derived virus
    Tomasz Laskus
    Division of Transplantation Medicine, Mayo Clinic Scottsdale, Scottsdale, Arizona 82529, USA
    J Infect Dis 185:417-21. 2002
    ..However, virus variants of likely extrahepatic origin can be detected in serum early after transplantation...
  14. pmc Negative-strand hepatitis C virus (HCV) RNA in peripheral blood mononuclear cells from anti-HCV-positive/HIV-infected women
    Tomasz Laskus
    Department of Medicine, St Joseph s Hospital and Medical Center, Phoenix, AZ 85013, USA
    J Infect Dis 195:124-33. 2007
    ..However, there are limited data regarding the prevalence of and the factors associated with extrahepatic replication...
  15. pmc Detection and analysis of hepatitis C virus sequences in cerebrospinal fluid
    Tomasz Laskus
    Division of Transplantation Medicine, Mayo Clinic, Scottsdale, Arizona 85259, USA
    J Virol 76:10064-8. 2002
    ..In four patients harboring different virus strains in serum and peripheral blood mononuclear cells (PBMC), CSF-derived virus was similar to that found in PBMC, which suggests that PBMC could carry HCV into the brain...
  16. ncbi request reprint Detection of hepatitis C virus sequences in brain tissue obtained in recurrent hepatitis C after liver transplantation
    Hugo E Vargas
    Division of Transplantation Medicine, Mayo Clinic Scottsdale, Scottsdale, AZ 85259, USA
    Liver Transpl 8:1014-9. 2002
    ..The exact lineage of cells permissive for HCV replication and the possible interaction between viral replication and cerebral function that may lead to depression remain to be elucidated...
  17. pmc Does HIV infection promote early kidney injury in women?
    Vasantha Jotwani
    Department of Medicine, San Francisco VA Medical Center, San Francisco, CA, USA
    Antivir Ther 19:79-87. 2014
    ....
  18. pmc Search for hepatitis C virus negative-strand RNA sequences and analysis of viral sequences in the central nervous system: evidence of replication
    Marek Radkowski
    Division of Transplantation Medicine, Mayo Clinic Scottsdale, Scottsdale, Arizona 85259, USA
    J Virol 76:600-8. 2002
    ..The results of the present study suggest that HCV can replicate in the central nervous system, probably in cells of the macrophage/monocyte lineage...
  19. ncbi request reprint Analysis of hepatitis C virus quasispecies transmission and evolution in patients infected through blood transfusion
    Tomasz Laskus
    Department of Medicine, Mayo Clinic Scottsdale, Scottsdale, Arizona, USA
    Gastroenterology 127:764-76. 2004
    ..Studies on hepatitis C virus (HCV) quasispecies dynamics in the natural course of infection are rare owing to difficulties in obtaining samples from the early phase of infection...
  20. ncbi request reprint Neuropsychological functioning in a cohort of HIV- and hepatitis C virus-infected women
    Jean L Richardson
    Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California, USA
    AIDS 19:1659-67. 2005
    ..To evaluate the neurocognitive function in 220 women enrolled in the Women's Interagency HIV Study (WIHS), a study of disease progression in women living with HIV/AIDS and in HIV-negative controls...
  21. pmc Sexual serosorting among women with or at risk of HIV infection
    Chenglong Liu
    Department of Medicine, Georgetown University, 2233 Wisconsin Ave NW, Suite 214, Washington, DC 20007, USA
    AIDS Behav 15:9-15. 2011
    ..Our analyses suggest that serosorting is occurring among both HIV-infected and HIV-uninfected women in this cohort...
  22. pmc Blinded, multicenter comparison of methods to detect a drug-resistant mutant of human immunodeficiency virus type 1 at low frequency
    Elias K Halvas
    Division of Infectious Diseases, Department of Medicine, University of Pittsburgh, S818 Scaife Hall, 3550 Terrace St, Pittsburgh, PA 15261, and Children s Hospital of Los Angeles, CA, USA
    J Clin Microbiol 44:2612-4. 2006
    ..1 to 0.4%. These technologies should help define the impact of low-frequency drug-resistant mutants on response to antiretroviral therapy...
  23. pmc Glycated haemoglobin in diabetic women with and without HIV infection: data from the Women's Interagency HIV Study
    Marshall J Glesby
    Department of Medicine, Weill Cornell Medical College, New York, NY, USA
    Antivir Ther 15:571-7. 2010
    ..Limited data suggest that glycated haemoglobin (haemoglobin A1c; A1C) values might not reflect glycaemic control accurately in HIV-infected individuals with diabetes...
  24. pmc Urinary markers of kidney injury and kidney function decline in HIV-infected women
    Michael G Shlipak
    Department of Medicine, San Francisco VA Medical Center, San Francisco, CA 94121, USA
    J Acquir Immune Defic Syndr 61:565-73. 2012
    ..We hypothesized that urine markers of kidney injury would be associated with declining kidney function among HIV-infected women...
  25. ncbi request reprint Prevalence and long-term effects of occult hepatitis B virus infection in HIV-infected women
    Judith I Tsui
    Department of Medicine, University of California San Francisco, San Francisco, CA, USA
    Clin Infect Dis 45:736-40. 2007
    ..CD4 cell counts of <200 cells/mm3 were more common among occult HBV-infected women than among those without occult HBV infection. Aminotransferase levels did not appear to be associated with being positive for HBV DNA...
  26. ncbi request reprint [Mother-to-infant HCV transmission--rate and course of HCV infection in children]
    Małgorzata Aniszewska
    1linika Chorób Zakaźnych Wieku Dzieciecego AM w Warszawie
    Przegl Epidemiol 61:7-15. 2007
    ..to establish the rate and course of HCV infection in infants born to HCV infected mothers and to determine abilities of prevention...
  27. pmc Hepatitis C virus quasispecies in HIV-infected women: role of injecting drug use and highly active antiretroviral therapy (HAART)
    Tomasz Laskus
    St Joseph s Hospital and Medical Center, Phoenix, AZ 85013, USA
    Hepatology 46:359-70. 2007
    ..No affect on HCV quasispecies dynamics was noted in relation to CD4 count or highly active antiretroviral therapy (HAART)...
  28. ncbi request reprint Evidence for viral persistence in patients who test positive for anti-hepatitis C virus antibodies and have normal alanine aminotransferase levels
    Marek Radkowski
    Institute of Infectious Diseases, Medical Academy, Warsaw 02 106, Poland
    J Infect Dis 191:1730-3. 2005
    ..Our results suggest that, in asymptomatic patients who test positive for anti-HCV antibodies, small quantities of HCV RNA commonly persist, even in patients who test negative for HCV RNA in serum by commercial tests...
  29. ncbi request reprint Infection of primary human macrophages with hepatitis C virus in vitro: induction of tumour necrosis factor-alpha and interleukin 8
    Marek Radkowski
    Institute of Infectious Diseases, Warsaw Medical Academy, Poland
    J Gen Virol 85:47-59. 2004
    ..In conclusion, these preliminary data suggest that primary human macrophages are susceptible to HCV infection in vitro and this infection is associated with the induction of cytokines TNF-alpha and IL-8...
  30. ncbi request reprint [Extrahepatic replication of the hepatitis C virus (HCV)]
    Agnieszka Kaminska
    Zakład Immunopatologii Chorób Zakaźnych i Pasozytniczych Akademii Medycznej w Warszawie
    Przegl Epidemiol 57:317-20. 2003
    ..Cells, tissues and organs supporting the active viral replication, particularly cells of the immune system, are presented...
  31. ncbi request reprint Hepatitis C virus quasi-species dynamics predict progression of fibrosis after liver transplantation
    Juan I Arenas
    Division of Transplantation Medicine, Mayo Clinic Scottsdale, Arizona 85259, USA
    J Infect Dis 189:2037-46. 2004
    ..The dynamics of hepatitis C virus (HCV) quasi species in the E2 region may correlate with the course of infection after orthotopic liver transplantation (OLT)...
  32. ncbi request reprint [Utility of multiplex PCR for diagnosis of neurological disorders in HIV-infected patients and patients with AIDS]
    Agnieszka Bednarska
    Wojewódzki Szpital Zakaźny w Warszawie
    Przegl Epidemiol 59:873-9. 2005
    ..Evaluation of multiplex PCR utility for diagnosis of central nervous system disorders in HIV-infected patients...