Ari S Nowacek

Summary

Affiliation: University of Nebraska Medical Center
Country: USA

Publications

  1. pmc Analyses of nanoformulated antiretroviral drug charge, size, shape and content for uptake, drug release and antiviral activities in human monocyte-derived macrophages
    Ari S Nowacek
    Department of Pharmacology and Experimental Neuroscience, University of Nebraska Medical Center, Omaha, NE 68198 5880, USA
    J Control Release 150:204-11. 2011
  2. pmc Comparative manufacture and cell-based delivery of antiretroviral nanoformulations
    Shantanu Balkundi
    Department of Pharmacology and Experimental Neuroscience, University of Nebraska Medical Center, Omaha, NE, USA
    Int J Nanomedicine 6:3393-404. 2011
  3. pmc Nanoformulated antiretroviral drug combinations extend drug release and antiretroviral responses in HIV-1-infected macrophages: implications for neuroAIDS therapeutics
    Ari S Nowacek
    Department of Pharmacology and Experimental Neuroscience, University of Nebraska Medical Center, Omaha, NE 68198 5880, USA
    J Neuroimmune Pharmacol 5:592-601. 2010
  4. pmc Pharmacotoxicology of monocyte-macrophage nanoformulated antiretroviral drug uptake and carriage
    Rafael F Bressani
    Department of Pharmacology and Experimental Neuroscience, University of Nebraska Medical Center, Omaha, Nebraska, USA
    Nanotoxicology 5:592-605. 2011
  5. pmc NanoART synthesis, characterization, uptake, release and toxicology for human monocyte-macrophage drug delivery
    Ari S Nowacek
    Department of Pharmacology and Experimental Neuroscience, University of Nebraska Medical Center, Omaha, NE 68198 5880, USA
    Nanomedicine (Lond) 4:903-17. 2009

Collaborators

  • GEORGETTE KANMOGNE
  • TATIANA BRONICH
  • Shantanu Balkundi
  • Rafael F Bressani
  • Howard E Gendelman
  • Joellyn McMillan
  • Upal Roy
  • Andrea Martinez-Skinner
  • R Lee Mosley
  • Alexander V Kabanov
  • Xinming Liu
  • Sangya Singh
  • Barrett Rabinow
  • Han Chen
  • Ram S Veerubhotla

Detail Information

Publications5

  1. pmc Analyses of nanoformulated antiretroviral drug charge, size, shape and content for uptake, drug release and antiviral activities in human monocyte-derived macrophages
    Ari S Nowacek
    Department of Pharmacology and Experimental Neuroscience, University of Nebraska Medical Center, Omaha, NE 68198 5880, USA
    J Control Release 150:204-11. 2011
    ..These studies bring this line of research a step closer to developing nanoART that can be used in the clinic to affect the course of HIV-1 infection...
  2. pmc Comparative manufacture and cell-based delivery of antiretroviral nanoformulations
    Shantanu Balkundi
    Department of Pharmacology and Experimental Neuroscience, University of Nebraska Medical Center, Omaha, NE, USA
    Int J Nanomedicine 6:3393-404. 2011
    ..We posit that the choice of drug and formulation composition may ultimately affect clinical utility...
  3. pmc Nanoformulated antiretroviral drug combinations extend drug release and antiretroviral responses in HIV-1-infected macrophages: implications for neuroAIDS therapeutics
    Ari S Nowacek
    Department of Pharmacology and Experimental Neuroscience, University of Nebraska Medical Center, Omaha, NE 68198 5880, USA
    J Neuroimmune Pharmacol 5:592-601. 2010
    ..The work brings us yet another step closer to realizing the utility of nanoART for virus-infected people...
  4. pmc Pharmacotoxicology of monocyte-macrophage nanoformulated antiretroviral drug uptake and carriage
    Rafael F Bressani
    Department of Pharmacology and Experimental Neuroscience, University of Nebraska Medical Center, Omaha, Nebraska, USA
    Nanotoxicology 5:592-605. 2011
    ..5mM ritonavir formulations did alter brain transendothelial electric resistance. These results underscore the potential importance of evaluating the physicochemical and functional properties of nanoART before human evaluations...
  5. pmc NanoART synthesis, characterization, uptake, release and toxicology for human monocyte-macrophage drug delivery
    Ari S Nowacek
    Department of Pharmacology and Experimental Neuroscience, University of Nebraska Medical Center, Omaha, NE 68198 5880, USA
    Nanomedicine (Lond) 4:903-17. 2009
    ..In attempts to bypass such limitations, nanoparticles containing ritonavir, indinavir and efavirenz (described as nanoART) were manufactured to assess macrophage-based drug delivery...