Research Topics
| Y W NovitskySummaryAffiliation: University of Connecticut Health Center Country: USA Publications
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Detail Information
Publications
Comparative evaluation of adhesion formation, strength of ingrowth, and textile properties of prosthetic meshes after long-term intra-abdominal implantation in a rabbitYuri W Novitsky
Division of Gastrointestinal and Minimally Invasive Surgery, Department of General Surgery, Carolinas Medical Center, Charlotte, North Carolina, USA
J Surg Res 140:6-11. 2007..The aim of this study was to compare the adhesion formation, tissue ingrowth, and textile characteristics one year after intra-abdominal placement of the commonly used prosthetic meshes...
Advantages of laparoscopic transabdominal preperitoneal herniorrhaphy in the evaluation and management of inguinal herniasYuri W Novitsky
Department of Surgery, University of Connecticut Health Center, 263 Farmington Avenue, Farmington, CT 06030 3955, USA
Am J Surg 193:466-70. 2007..We aimed to establish the rates and contributing patient factors to errors in the preoperative assessment...
Do the risks of emergent colectomy justify nonoperative management strategies for recurrent diverticulitis?Yuri W Novitsky
Department of Surgery, University of Connecticut Health Center, Farmington, CT, USA
Am J Surg 197:227-31. 2009..This approach, however, may result in more frequent acute attacks requiring emergent colectomy. Our aim was to compare the colectomy outcomes for diverticulitis in the elective and acute settings...
Immunohistochemical analysis of host reaction to heavyweight-, reduced-weight-, and expanded polytetrafluoroethylene (ePTFE)-based meshes after short- and long-term intraabdominal implantationsY W Novitsky
Department of Surgery, University of Connecticut Health Center, Farmington, CT 06030, USA
Surg Endosc 22:1070-6. 2008..This study aimed to characterize the degree of short- and long-term inflammatory changes induced by common prosthetic meshes...
Anisotropic evaluation of synthetic surgical meshesE R Saberski
University of Connecticut School of Medicine, Farmington, Connecticut, USA
Hernia 15:47-52. 2011..Haphazard orientation of anisotropic mesh material can contribute to inconsistent surgical outcomes. We aimed to characterize and compare anisotropic properties of commonly used synthetic meshes...
Hand-assisted laparoscopic splenectomy in the setting of splenomegalyG K Kaban
Department of Surgery, University of Massachusetts, 55 Lake Avenue North, Worcester, MA 01655, USA
Surg Endosc 18:1340-3. 2004..Hand-assisted laparoscopic surgery (HALS) devices may be well suited to splenectomy in cases of splenomegaly...
Prospective histologic evaluation of intra-abdominal prosthetics four months after implantation in a rabbit modelAndrew G Harrell
Division of Gastrointestinal and Minimally Invasive Surgery, Department of General Surgery, Carolinas Medical Center, 1000 Blythe Boulevard, MEB 601, Charlotte, NC 28203, USA
Surg Endosc 21:1170-4. 2007..We evaluated the host response to intraperitoneal placement of several prosthetics currently used in clinical practice...
Activation of human mononuclear cells by porcine biologic meshes in vitroS B Orenstein
Connecticut Comprehensive Center for Hernia Repair, Department of Surgery, University of Connecticut Health Center, 263 Farmington Avenue MC 3955, Farmington, CT 06030, USA
Hernia 14:401-7. 2010..Exaggerated activation of M/MØs may deleteriously influence mesh integration and remodeling. We hypothesized that common porcine meshes induce the differential activation of M/MØs in vitro...
In vitro infectability of prosthetic mesh by methicillin-resistant Staphylococcus aureusA G Harrell
Carolinas Laparoscopic and Advanced Surgery Program, Department of General Surgery, Carolinas Medical Center, Charlotte, NC 28203, USA
Hernia 10:120-4. 2006..Standard PTFE (Dualmesh) also had less bacterial adherence. Vypro demonstrated an increase in bacterial adherence; this was possibly due to the multifilament polyglactin 910 weaved within the prolene component of the mesh...
Laparoscopic parastomal hernia repair using a nonslit mesh techniqueG J Mancini
Department of Surgery, University of Missouri, One Hospital Drive, Columbia, MO 65203, USA
Surg Endosc 21:1487-91. 2007..The management of parastomal hernia is associated with high morbidity and recurrence rates (20-70%). This study investigated a novel laparoscopic approach and evaluated its outcomes...
Combined open and laparoscopic approach to chronic pain following open inguinal hernia repairM J Rosen
Division of Gastrointestinal and Minimally Invasive Surgery, Carolinas Medical Center, P.O. Box 32861, Charlotte, NC 28232, USA
Hernia 10:20-4. 2006..It may be the preferred technique for the definitive management of chronic neuralgia after prior open hernia repair...
Severely disordered esophageal peristalsis is not a contraindication to laparoscopic Nissen fundoplicationY W Novitsky
Department of Surgery, Carolinas Medical Center, Charlotte, NC 28202, USA
Surg Endosc 21:950-4. 2007..We hypothesized that LNF is also acceptable for patients with severe esophageal dysmotility...
Prospective evaluation of adhesion formation and shrinkage of intra-abdominal prosthetics in a rabbit modelAndrew G Harrell
Carolinas Hernia Center, Division of Gastrointestinal and Minimally Invasive Surgery, Department of General Surgery, Charlotte, North Carolina 28203, USA
Am Surg 72:808-13; discussion 813-4. 2006..Each prosthetic generates a varied host reaction. Better understanding of these reactions can allow a suitable prosthetic to be chosen for a given patient in clinical practice...
Effects of mast cell modulation on early host response to implanted synthetic meshesS B Orenstein
Department of Surgery, University of Connecticut Health Center, Farmington, CT 06030, USA
Hernia 14:511-6. 2010..Investigation of the role of MCs in mediating local tissue responses to synthetic hernia meshes has been very limited to date. We aimed to determine the effects of MCs/MC products in mice undergoing synthetic mesh implantation...
The net immunologic advantage of laparoscopic surgeryY W Novitsky
Department of Surgery, University of Massachusetts Medical School, Worcester, MA, USA
Surg Endosc 18:1411-9. 2004..In addition to improved cosmesis and faster functional recovery, a patient undergoing laparoscopic surgery may benefit most from a net immunologic advantage...
Intra-abdominal placement of antimicrobial-impregnated mesh is associated with noninfectious feverWilliam S Cobb
Division of Gastrointestinal and Minimally Invasive Surgery, Carolinas Hernia Center, Carolinas Medical Center, Department of Surgery, Charlotte, North Carolina 28203, USA
Am Surg 72:1205-8; discussion 1208-9. 2006..In our patients, the evaluation and management of these fevers resulted in a significantly longer hospital stay...
Laparoscopic ventral hernia repair in obese patients: a new standard of careYuri W Novitsky
Carolinas Laparoscopic and Advanced Surgery Program, Department of General Surgery, Carolinas Medical Center, PO Box 32861, Charlotte, NC 28232, USA
Arch Surg 141:57-61. 2006..5% suggests improved efficacy of LVHR compared with the historical rates among control subjects undergoing open surgery. In experienced hands, LVHR may be the approach of choice for most patients with a body mass index of 30 or more...
Management of infections of polytetrafluoroethylene-based meshB Lauren Paton
Division of Gastrointestinal and Minimally Invasive Surgery, Carolinas Medical Center, Charlotte, North Carolina 28203, USA
Surg Infect (Larchmt) 8:337-41. 2007..Although salvage of infected mesh has been reported, the feasibility, efficacy, and long-term outcomes of this practice remain unclear. The purpose of this study was to delineate a protocol for salvaging infected ePTFE mesh...
Open preperitoneal retrofascial mesh repair for multiply recurrent ventral incisional herniasYuri W Novitsky
Carolinas Hernia Center, Division of Gastrointestinal and Minimally Invasive Surgery, Department of Surgery, Carolinas Medical Center, Charlotte, NC 28203, USA
J Am Coll Surg 203:283-9. 2006..Given the technical challenge, surgical care of patients with MRH may be best provided in referral centers with interest and expertise in complex hernia repairs...
Small bowel obstruction owing to displaced spiral tack after laparoscopic TAPP inguinal hernia repairHeidi L Fitzgerald
Connecticut Comprehensive Center for Hernia Repair, Department of Surgery, University of Connecticut Health Center Farmington, CT 06030, USA
Surg Laparosc Endosc Percutan Tech 20:e132-5. 2010..This is usually attributed to inadequate peritoneal closure, trocar site herniation, or adhesions. We report a case of small bowel obstruction caused by a displaced spiral tack used for the peritoneal closure during TAPP hernia repair...
Use of a laparoscopic hand-assist device for accessory splenectomyG K Kaban
Department of Surgery, University of Massachusetts Medical School, 55 Lake Avenue North, Worcester, MA 01655, USA
Surg Endosc 18:1001. 2004..If the AS is not identified at laparoscopy, the insertion of a hand-assist device is an alternative to a full laparotomy...
Meshes in hernia repairYuri W Novitsky
Division of Gastrointestinal and Minimally Invasive Surgery, Carolinas Medical Center, Charlotte, NC, USA
Surg Technol Int 16:123-7. 2007....
Optional vena cava filters for patients with high thromboembolic risk: questions to be answeredRonald F Sing
Carolinas Laparoscopic and Advanced Surgery Program, Carolinas Medical Center, Charlotte, NC 28203, USA
Surg Innov 12:195-202. 2005..Recent reports have demonstrated the safety and feasibility of these devices in appropriate patients, but a number of questions have arisen regarding their use...
Is the use of a bougie necessary for laparoscopic Nissen fundoplication?Yuri W Novitsky
Department of Surgery, University of Massachusetts Medical School, 55 Lake Ave N, Worcester, MA 01655, USA
Arch Surg 137:402-6. 2002..However, a bougie may cause intraoperative gastric and esophageal perforations. We hypothesized that LNF is safe and effective when performed without a bougie...
Feasibility of laparoscopic adrenalectomy for large adrenal massesYuri W Novitsky
Department of Surgery, University of Massachusetts Medical School, Worcester, USA
Surg Laparosc Endosc Percutan Tech 13:106-10. 2003..Both right and left large adrenal masses can be approached laparoscopically with equal success. The role of minimally invasive approaches to adrenal malignancies necessitates further investigation...
Immunologic effects of hand-assisted surgery on peritoneal macrophages: comparison to open and standard laparoscopic approachesYuri W Novitsky
Department of Surgery, University of Massachusetts Medical School, 55 Lake Avenue North, Ste H1 760, Worcester, MA 01655, USA
Surgery 139:39-45. 2006..Although laparoscopy (L) is known to elicit a smaller attenuation of peritoneal host defenses, compared with open (O) surgery, effects of the hand-assisted (HA) approach have not been investigated to date...
Laparoscopic expertise increases hospital volume of adrenal surgeryYuri W Novitsky
Department of Surgery, Division of GI and Minimally Invasive Surgery, Carolinas Medical Center, Charlotte, North Carolina 28203, USA
Surg Innov 13:109-14. 2006..Offering a laparoscopic approach has altered physicians' referral patterns and has significantly increased the volume of adrenal surgery at the institution...
Laparoscopic curative resection of pheochromocytomasKent W Kercher
Department of Surgery, Carolinas Medical Center, Charlotte, North Carolina 28232, USA
Ann Surg 241:919-26; discussion 926-8. 2005..A short hospital stay with minimal operative morbidity and eradication of endocrinopathy support the minimally invasive approach for adrenalectomy in the setting of pheochromocytoma...
Comparison of generic versus specific quality-of-life scales for mesh hernia repairsB Todd Heniford
Carolinas Hernia Center, Division of Gastrointestinal and Minimally Invasive Surgery, Charlotte, NC 28203, USA
J Am Coll Surg 206:638-44. 2008..We propose a new quality-of-life survey, the Carolinas Comfort Scale (CCS), pertaining specifically to patients undergoing hernia repair with mesh; our goal was to test the validity and reliability of this survey...
Use of laparoscopy in evaluation and treatment of penetrating and blunt abdominal injuriesGordie K Kaban
Department of Surgery, University of Massachusetts Medical School, Worcester, Massachusetts, USA
Surg Innov 15:26-31. 2008..Use of laparoscopy in selected patients with blunt and penetrating abdominal trauma is safe, minimizes nontherapeutic laparotomies, and allows for minimal invasive management of selected intra-abdominal injuries...
Staple line bleeding following laparoscopic splenectomy: intraoperative prevention and postoperative management with splenic artery embolizationKent W Kercher
Department of Surgery, University of Massachusetts Medical School, Worcester, MA 01655, USA
Surg Laparosc Endosc Percutan Tech 13:353-6. 2003..In this paper we identify and discuss important technical aspects of obtaining hilar vascular control during LS and report the first use of postoperative splenic artery embolization to control staple line bleeding following LS...
The effect of preoperative corticosteroids on peritoneal macrophage function after laparoscopic and open abdominal surgery in a rat modelThomas M Schmelzer
Department of General Surgery, Carolinas Medical Center, 1000 Blythe Blvd, MEB 601, Charlotte, NC 28203, USA
Am J Surg 196:920-4; discussion 924-5. 2008..This study examined the influence of minimally invasive techniques and preoperative corticosteroid administration on postoperative peritoneal macrophage phagocytic activity...
Human monocyte activation by biologic and biodegradable meshes in vitroSean B Orenstein
Department of Surgery, Connecticut Comprehensive Center for Hernia Repair, University of Connecticut Health Center, 263 Farmington Avenue MC 3955, Farmington, CT 06030, USA
Surg Endosc 24:805-11. 2010..Although BMs have been increasingly used in hernia repairs worldwide, to date, investigations of inflammatory responses to various BMs have been limited...
Evaluation of the efficacy of the electrosurgical bipolar vessel sealer (LigaSure) devices in sealing lymphatic vesselsYuri W Novitsky
Department of Surgery, Carolinas Laparoscopic and Advanced Surgery Program, Carolinas Medical Center, Charlotte, NC 28203, USA
Surg Innov 12:155-60. 2005..The seals created by all 3 devices burst at markedly supraphysiologic intraluminal pressures. Ongoing randomized human trials may prove the clinical benefits of the routine use of EBVS devices for various tissue dissections...
Laparoscopic Heller myotomy for achalasia in 101 patients: can successful symptomatic outcomes be predicted?Michael J Rosen
Division of Gastrointestinal and Minimally Invasive Surgery, Department of Surgery, Carolinas Medical Center, Charlotte, North Carolina 28203, USA
Surg Innov 14:177-83. 2007..Improvement in dysphagia can be expected in more than 95% of patients. Younger patients tended to have better improvement of dysphagia. Predicting the patients at higher risk for postoperative reflux remains elusive at this time...
Current aspects of surgical management of GERDYuri W Novitsky
Division of Gastrointestinal and Minimally-invasive Surgery, Carolinas Medical Center, Charlotte, NC, USA
Surg Technol Int 15:53-62. 2006..In experienced hands, these patients can still benefit from minimally-invasive restorative or "re-do" fundoplications with minimal perioperative morbidity and good long-term results...
Benefits of laparoscopic adrenalectomy: a 10-year single institution experienceLiam A Haveran
Department of Surgery, University of Massachusetts Medical Center, Worcester, MA, USA
Surg Laparosc Endosc Percutan Tech 16:217-21. 2006..The availability of advanced laparoscopy has resulted in a significant increase in the number of adrenalectomies performed at our institution without a shift in surgical indications...
Advantages of laparoscopic appendectomy in the elderlyAndrew G Harrell
Division of Gastrointestinal and Minimally Invasive Surgery, Department of General Surgery, Carolinas Medical Center, Charlotte, North Carolina 28203, USA
Am Surg 72:474-80. 2006..Laparoscopy may be the preferred approach in elderly patients who require appendectomy...
Long-term outcomes of laparoscopic resection of gastric gastrointestinal stromal tumorsYuri W Novitsky
Division of Gastrointestinal and Minimally Invasive Surgery, Department of Surgery, Carolinas Medical Center, 1000 Blythe Boulevard, Charlotte, NC 28203, USA
Ann Surg 243:738-45; discussion 745-7. 2006..Given these findings as well as the advantages afforded by minimally invasive surgery, a laparoscopic approach may be the preferred resection technique in most patients with small- and medium-sized gastric GISTs...
Advantages of mini-laparoscopic vs conventional laparoscopic cholecystectomy: results of a prospective randomized trialYuri W Novitsky
Department of Surgery, University of Massachusetts Medical School, Worcester, USA
Arch Surg 140:1178-83. 2005..We hypothesized that LC using miniports (M-LC) is safe and produces less incisional pain and better cosmetic results than LC performed conventionally (C-LC)...
Optimizing laparoscopic task efficiency: the role of camera and monitor positionsLiam A Haveran
Department of Surgery, University of Massachusetts Medical Center, Worcester, Massachusetts, USA
Surg Endosc 21:980-4. 2007..We aimed to determine the influence of monitor/camera position on the laparoscopic performance of surgeons of varying skill levels...
Clinical outcomes of laparoscopic adrenalectomy for lateralizing nodular hyperplasiaYuri W Novitsky
Department of Surgery, Carolinas Medical Center, Charlotte, NC 28203, USA
Surgery 138:1009-16; discussion 1016-7. 2005..When lateralization of aldosterone production is noted, laparoscopic adrenalectomy provides significant clinical improvement even in patients with a pathologic diagnosis of NAH...
Fatal cardiac air embolismYuri W Novitsky
Department of Surgery, Carolinas Medical Centre, P.O. Box 32861, Charlotte, NC 28232, USA
Injury 37:78-80. 2006
Predictors of complication and suboptimal weight loss after laparoscopic Roux-en-Y gastric bypass: a series of 188 patientsRichard A Perugini
Department of Surgery and the Informatics Unit, University of Massachusetts Medical School, Worcester 01655, USA
Arch Surg 138:541-5; discussion 545-6. 2003..An analysis of patients undergoing laparoscopic Roux-en-Y gastric bypass (RYGB) may identify factors predictive of complication and of suboptimal weight loss...
Laparoscopic surgery and the nuances of systemic immunityYuri W Novitsky
J Clin Gastroenterol 34:109-10. 2002
