Research Topics
| MELINDA ANN NOVAKSummaryAffiliation: University of Massachusetts Country: USA Publications
Research Grants
| Collaborators
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Detail Information
Publications
Effects of puzzle feeders on pathological behavior in individually housed rhesus monkeysM A Novak
New England Regional Primate Research Center, Harvard Medical School, Southborough, Massachusetts, USA
Am J Primatol 46:213-27. 1998..They also yield transient reductions in whole body stereotypy, an effect that does not extend beyond the direct manipulation of the feeder. Puzzle feeders are ineffective in alleviating self-injurious behavior...- Self-injurious behavior in rhesus monkeys: new insights into its etiology, physiology, and treatmentMelinda A Novak
Department of Psychology, University of Massachusetts, Amherst, Massachusetts 01003 7710, USA
Am J Primatol 59:3-19. 2003..The potentially reinforcing effects of SIB may account for the failure of some treatment regimens. These findings are compared to studies of SIB in humans, and concordances are identified... 
Alopecia: possible causes and treatments, particularly in captive nonhuman primatesMelinda A Novak
Department of Psychology, University of Massachusetts, Amherst, Massachusetts, USA
Comp Med 59:18-26. 2009..Alopecia in nonhuman primates is a multifaceted disorder with many potential sources. For this reason, appropriate testing for various disease conditions should be completed before alopecia is considered to be related to stress...- A rhesus monkey model of self-injury: effects of relocation stress on behavior and neuroendocrine functionMatthew D Davenport
Division of Behavioral Biology, New England Primate Research Center, Harvard Medical School, Southborough, Massachusetts, USA
Biol Psychiatry 63:990-6. 2008..This study investigated the short- and long-term behavioral and neuroendocrine responses of SIB and control monkeys to the stress of relocation... - Effects of shampoo and water washing on hair cortisol concentrationsAmanda F Hamel
Neuroscience and Behavior Graduate Program, University of Massachusetts, Amherst, MA 01003 9271, USA
Clin Chim Acta 412:382-5. 2011..Currently unknown, however, is the extent of potential cortisol loss from hair that has been repeatedly exposed to shampoo and/or water... - Surrogate mobility and orientation affect the early neurobehavioral development of infant rhesus macaques (Macaca mulatta)Amanda M Dettmer
Neuroscience and Behavior Program Tobin Hall, 135 Hicks Way, University of Massachusetts, Amherst, MA 01003, USA
Dev Psychobiol 50:418-22. 2008.... 
Laterality in semi-free-ranging black and white ruffed lemurs (Varecia variegata variegata): head-tilt correlates with hand use during feedingEliza L Nelson
Department of Psychology, University of Massachusetts, Tobin Hall, 135 Hicks Way, Amherst, MA 01003, USA
Am J Primatol 71:1032-40. 2009..Additional studies on patterns of laterality would be informative for understanding how laterality has changed across the primate order and the adaptive significance of laterality in primates...- Hair cortisol predicts object permanence performance in infant rhesus macaques (Macaca mulatta)Amanda M Dettmer
Neuroscience and Behavior Program, University of Massachusetts, Tobin Hall, 135 Hicks Way, Amherst, MA 01003, USA
Dev Psychobiol 51:706-13. 2009..01) and screen tasks (p < 0.05). These data are the first to implicate hair cortisol as a reliable predictor of early cognitive performance in infant macaque monkeys... - Fenfluramine challenge, self-injurious behavior, and aggression in rhesus monkeysStefan Tiefenbacher
New England Primate Research Center, Harvard Medical School, One Pine Hill Drive, Southborough, MA 01772 9102, USA
Physiol Behav 80:327-31. 2003..Moreover, a dose-dependent response to FEN was observed only for prolactin, suggesting that this variable is more appropriate than cortisol as an endpoint for FEN challenge in monkeys... - Altered hypothalamic-pituitary-adrenocortical function in rhesus monkeys (Macaca mulatta) with self-injurious behaviorStefan Tiefenbacher
Harvard Medical School, New England Regional Primate Research Center, Division of Behavioral Biology, One Pine Hill Drive, Southborough, MA 01772, USA
Psychoneuroendocrinology 29:501-15. 2004..e. self-directed biting, and to the recency of a wounding episode. It remains to be determined whether humans who exhibit SIB show similar alterations in HPA function... - Analysis of endogenous cortisol concentrations in the hair of rhesus macaquesMatthew D Davenport
Division of Behavioral Biology, New England Primate Research Center, Harvard Medical School, 1 Pine Hill Drive, Southborough, MA 01772, USA
Gen Comp Endocrinol 147:255-61. 2006.... - The efficacy of diazepam treatment for the management of acute wounding episodes in captive rhesus macaquesStefan Tiefenbacher
New England Primate Research Center, Harvard Medical School, Southborough, Massachusetts 017721, USA
Comp Med 55:387-92. 2005..Our findings suggest that SIB is not a homogeneous disorder in rhesus monkeys; rather, distinct subtypes exist that require different treatment approaches... - Environmental enrichment for nonhuman primates: theory and applicationCorrine K Lutz
Division of Behavioral Biology, New England Primate Research Center, Harvard Medical School, Southborough, MA, USA
ILAR J 46:178-91. 2005..Only social contact satisfies the goal of promoting a wide variety of species-typical activities while at the same time reducing or preventing the development of abnormal behavior... - The effect of rearing experience and TPH2 genotype on HPA axis function and aggression in rhesus monkeys: a retrospective analysisGuo Lin Chen
Harvard Medical School, New England Primate Research Center, Southborough, MA 01772, USA
Horm Behav 57:184-91. 2010..Our findings strengthen the involvement of G x E interactions at the loci of serotonergic genes and the utility of the nonhuman primate to model G x E interactions in the development of human neuropsychiatric diseases... - The anxiogenic drug FG7142 increases self-injurious behavior in male rhesus monkeys (Macaca mulatta)Christine A Major
New England Primate Research Center, Harvard Medical School, Southborough, MA, United States
Life Sci 85:753-8. 2009..Here, we determined whether rhesus monkeys increase their self-directed biting following a challenge with the anxiogenic compound N-methyl-beta-carboline-3-carboxamide (FG7142)... - Polymorphisms in the 3' UTR of the serotonin transporter are associated with cognitive flexibility in rhesus macaquesEric J Vallender
Division of Neurochemistry, New England Primate Research Center, Harvard Medical School, Southborough, Massachusetts 01772, USA
Am J Med Genet B Neuropsychiatr Genet 150:467-75. 2009.... - The physiology and neurochemistry of self-injurious behavior: a nonhuman primate modelStefan Tiefenbacher
Division of Behavioral Biology, New England Primate Research Center, Harvard Medical School, Southborough, MA 01772, USA
Front Biosci 10:1-11. 2005..Implications of this hypothesis for understanding self-injury in patients with borderline personality disorder and members of the general population are discussed...
Research Grants
- Self-Injurious Behavior and Primate Well-BeingMelinda Novak; Fiscal Year: 2006..In Specific Aim 4, we will establish effective pharmacological treatments for SIB in monkeys and evaluate individual differences in treatment efficacy. ..
- SELF INJURIOUS BEHAVIOR AND PRIMATE WELL BEINGMelinda Novak; Fiscal Year: 2004..These studies should provide important new information concerning the pathophysiology of SIB in monkeys and should lead to the development of useful treatment strategies. ..
- SELF INJURIOUS BEHAVIOR AND PRIMATE WELL BEINGMelinda Novak; Fiscal Year: 1999..This information is critical for developing effective interventions and improving colony management. ..
- Self-Injurious Behavior and Primate Well-BeingMELINDA ANN NOVAK; Fiscal Year: 2010..In Specific Aim 4, we will establish effective pharmacological treatments for SIB in monkeys and evaluate individual differences in treatment efficacy. ..