Igor L Novak

Summary

Affiliation: University of Connecticut Health Center
Country: USA

Publications

  1. pmc Diffusion in cytoplasm: effects of excluded volume due to internal membranes and cytoskeletal structures
    Igor L Novak
    Richard D Berlin Center for Cell Analysis and Modeling, Department of Cell Biology, University of Connecticut Health Center, Farmington, Connecticut, USA
    Biophys J 97:758-67. 2009
  2. pmc Diffusion amid random overlapping obstacles: similarities, invariants, approximations
    Igor L Novak
    Richard D Berlin Center for Cell Analysis and Modeling, Department of Cell Biology, University of Connecticut Health Center, Farmington, Connecticut 06030, USA
    J Chem Phys 134:154104. 2011
  3. pmc An open model of actin dendritic nucleation
    Jonathon A Ditlev
    Richard D Berlin Center for Cell Analysis and Modeling, University of Connecticut Health Center, Farmington, CT 06030 1507, USA
    Biophys J 96:3529-42. 2009
  4. pmc Virtual Cell: computational tools for modeling in cell biology
    Diana C Resasco
    Richard D Berlin Center for Cell Analysis and Modeling, Department of Cell Biology, University of Connecticut Health Center, Farmington, CT, USA
    Wiley Interdiscip Rev Syst Biol Med 4:129-40. 2012
  5. pmc Quantitative analysis of G-actin transport in motile cells
    Igor L Novak
    Center for Cell Analysis and Modeling, University of Connecticut Health Center, Farmington, Connecticut 06030, USA
    Biophys J 95:1627-38. 2008
  6. pmc Actin bundling: initiation mechanisms and kinetics
    Pavel Kraikivski
    Richard D Berlin Center for Cell Analysis and Modeling, Department of Cell Biology, University of Connecticut Health Center, Farmington, CT 06030, USA
    Phys Rev Lett 101:128102. 2008
  7. ncbi request reprint Cooperativity between cell contractility and adhesion
    Igor L Novak
    Department of Cell Biology, University of Connecticut Health Center, Farmington, Connecticut 06030, USA
    Phys Rev Lett 93:268109. 2004

Collaborators

Detail Information

Publications7

  1. pmc Diffusion in cytoplasm: effects of excluded volume due to internal membranes and cytoskeletal structures
    Igor L Novak
    Richard D Berlin Center for Cell Analysis and Modeling, Department of Cell Biology, University of Connecticut Health Center, Farmington, Connecticut, USA
    Biophys J 97:758-67. 2009
    ..The study lays the foundation for an accurate coarse-grain formulation that would account for cytoplasm heterogeneity on a micron scale and binding of tracers to intracellular structures...
  2. pmc Diffusion amid random overlapping obstacles: similarities, invariants, approximations
    Igor L Novak
    Richard D Berlin Center for Cell Analysis and Modeling, Department of Cell Biology, University of Connecticut Health Center, Farmington, Connecticut 06030, USA
    J Chem Phys 134:154104. 2011
    ..In 3D, the similarities of effective diffusion yield a simple multiplication "rule" that provides a fast means of estimating D(eff) for a mixture of overlapping obstacles of different shapes with comparable sizes...
  3. pmc An open model of actin dendritic nucleation
    Jonathon A Ditlev
    Richard D Berlin Center for Cell Analysis and Modeling, University of Connecticut Health Center, Farmington, CT 06030 1507, USA
    Biophys J 96:3529-42. 2009
    ..Because this model, with the simulation results, is "open source", in the sense that it is publicly available and editable through the Virtual Cell database (http://vcell.org), it can be accessed, analyzed, modified, and extended...
  4. pmc Virtual Cell: computational tools for modeling in cell biology
    Diana C Resasco
    Richard D Berlin Center for Cell Analysis and Modeling, Department of Cell Biology, University of Connecticut Health Center, Farmington, CT, USA
    Wiley Interdiscip Rev Syst Biol Med 4:129-40. 2012
    ..In this article, we review new robust computational tools recently deployed in VCell for treating spatially resolved models...
  5. pmc Quantitative analysis of G-actin transport in motile cells
    Igor L Novak
    Center for Cell Analysis and Modeling, University of Connecticut Health Center, Farmington, Connecticut 06030, USA
    Biophys J 95:1627-38. 2008
    ..We discuss biological implications of the local and global regimes of the G-actin transport...
  6. pmc Actin bundling: initiation mechanisms and kinetics
    Pavel Kraikivski
    Richard D Berlin Center for Cell Analysis and Modeling, Department of Cell Biology, University of Connecticut Health Center, Farmington, CT 06030, USA
    Phys Rev Lett 101:128102. 2008
    ..We propose an experiment for determining which of the two mechanisms is involved in the in vitro bundle formation...
  7. ncbi request reprint Cooperativity between cell contractility and adhesion
    Igor L Novak
    Department of Cell Biology, University of Connecticut Health Center, Farmington, Connecticut 06030, USA
    Phys Rev Lett 93:268109. 2004
    ..The model predicts that the focal adhesions propagate by treadmilling with a velocity proportional to the integrin diffusion coefficient...