Ryan W NorrisSummaryAffiliation: University of Vermont Country: USA Publications
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Publications
Coevolution between cannabinoid receptors and endocannabinoid ligandsJohn M McPartland
GW Pharmaceuticals, Middlebury, VT 05753, USA
Gene 397:126-35. 2007..Therefore we propose that cannabinoid receptors initially coevolved with a fatty acid ester ligand (akin to 2-AG) in ancestral metazoans, and affinity for fatty acid ethanolamide ligands (e.g., AEA) evolved thereafter...
The phylogenetic position of the zokors (Myospalacinae) and comments on the families of muroids (Rodentia)Ryan W Norris
Department of Biology, University of Vermont, Burlington, VT 05405, USA
Mol Phylogenet Evol 31:972-8. 2004..Finally, our analyses suggest that the earlier placement of Myospalax as a member of the Cricetinae is the result of a single misidentified specimen, which was not a Myospalax...
A shifted repertoire of endocannabinoid genes in the zebrafish (Danio rerio)J M McPartland
GW Pharmaceuticals, Middlebury, VT 05753, USA
Mol Genet Genomics 277:555-70. 2007..In conclusion, the zebrafish genome expresses a shifted repertoire of endocannabinoid genes. In vitro analyses are warranted before using zebrafish for cannabinoid development testing...
Tempo and mode in the endocannaboinoid systemJohn M McPartland
GW Pharmaceuticals Ltd, Middlebury, VT 05753, USA
J Mol Evol 65:267-76. 2007..In conclusion, the endocannabinoid system is collectively under strong purifying selection, although some genes show evidence of adaptive evolution...
