Research Topics
Genomes and GenesSpecies | Jill NorrisSummaryAffiliation: University of Colorado Health Sciences Center Country: USA Publications
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Publications
Genome scan linkage results for longitudinal systolic blood pressure phenotypes in subjects from the Framingham Heart StudyKatherine James
Department of Preventive Medicine and Biometrics, University of Colorado Health Sciences Center, Denver, Colorado, USA
BMC Genet 4:S83. 2003....- Comparison between two analytic strategies to detect linkage to obesity with genetically determined age of onset: the Framingham Heart StudyCorinne D Engelman
Department of Preventive Medicine and Biometrics, University of Colorado Health Sciences Center, Denver, Colorado, USA
BMC Genet 4:S90. 2003..The first is to consider a person affected if they possess the trait before a certain age (an early age of onset phenotype). The second is to define the phenotype based on the residual from a survival analysis... 
Risk of celiac disease autoimmunity and timing of gluten introduction in the diet of infants at increased risk of diseaseJill M Norris
Department of Preventive Medicine and Biometrics, University of Colorado at Denver and Health Sciences Center, Denver, CO 80262, USA
JAMA 293:2343-51. 2005..While gluten ingestion is responsible for the signs and symptoms of celiac disease, it is not known what factors are associated with initial appearance of the disease...- Timing of initial exposure to cereal grains and the risk of wheat allergyJill A Poole
Division of Allergy and Clinical Immunology, Department of Medicine and Pediatrics, National Jewish Medical and Research Center, Denver, Colorado, USA
Pediatrics 117:2175-82. 2006..The aim of this study was to examine the association between cereal-grain exposures (wheat, barley, rye, oats) in the infant diet and development of wheat allergy... - Quantitative trait loci for abdominal fat and BMI in Hispanic-Americans and African-Americans: the IRAS Family studyJ M Norris
Department of Preventive Medicine and Biometrics, University of Colorado Health Sciences Center, Denver, CO 80262, USA
Int J Obes (Lond) 29:67-77. 2005..To conduct linkage analysis for body mass index (BMI, kg/m2), waist-to-hip ratio (WHR), visceral adipose tissue mass (VAT, cm2) and subcutaneous adipose tissue mass (SAT, cm2) using a whole genome scan... - Omega-3 polyunsaturated fatty acid intake and islet autoimmunity in children at increased risk for type 1 diabetesJill M Norris
Department of Preventive Medicine and Biostatistics, University of Colorado at Denver and Health Sciences Center, Denver, CO 80262, USA
JAMA 298:1420-8. 2007..Cod liver oil supplements in infancy have been associated with a decreased risk of type 1 diabetes mellitus in a retrospective study... - Timing of initial cereal exposure in infancy and risk of islet autoimmunityJill M Norris
Department of Preventive Medicine and Biometrics, University of Colorado Health Sciences Center, Denver 80262, USA
JAMA 290:1713-20. 2003..Dietary exposures in infancy have been implicated, albeit inconsistently, in the etiology of type 1 diabetes mellitus (DM)... - Elevated C-reactive protein levels in the development of type 1 diabetesH Peter Chase
Department of Pediatrics, The Barbara Davis Center for Childhood Diabetes, Denver, Colorado, USA
Diabetes 53:2569-73. 2004..The elevated CRP levels may provide an additional marker for risk of progression to type 1 diabetes... - Rapid mass spectrometric analysis for ascorbate and related organic acids in small volumes of plasma for use in pediatric subjectsJ C Deutsch
Department of Medicine, Denver Veterans Affairs Hospital and University of Colorado Health Sciences Center, 80220, USA
J Chromatogr B Biomed Sci Appl 726:79-84. 1999..Analysis on 28 subjects fell within the expected range for plasma ascorbate 68+/-29 microm (11.9+/-5.0 microg/ml) and established a normal range for plasma threonate of 28.1+/-2.4 microm (3.8+/-0.4 microg/ml)... - Lack of association between early childhood immunizations and beta-cell autoimmunityP M Graves
Department of Preventive Medicine and Biometrics, University of Colorado Health Sciences Center, Denver 80262, USA
Diabetes Care 22:1694-7. 1999..To determine whether early childhood immunization history affects the risk of developing the beta-cell autoimmunity that precedes type 1 diabetes... - Epidemiology of type 1 Diabetes MellitusMarian Rewers
Barbara Davis Center for Childhood Diabetes, University of Colorado, Health Sciences Center, Denver, USA
Adv Exp Med Biol 552:219-46. 2004..Current research effort is focused on identification of the genetic and environmental determinants of this process and the ways they interact... 
An exploration of Glo-3A antibody levels in children at increased risk for type 1 diabetes mellitusM Simpson
Department of Epidemiology, Colorado School of Public Health, Colorado, USA
Pediatr Diabetes 10:563-72. 2009....- Investigation of a candidate gene, environment, and G x E interaction using case-control and case-parent study designsJ M Norris
Univ. of Colorado Health Sci. Center, Department of Preventive Medicine and Biometrics, 4200 East Ninth Ave, Box C245, Denver, CO 80262, USA
Genet Epidemiol 21:S843-8. 2001..Using the case-parent study design in the same population, we detected association between SNPs within CG1 and disease, but no G x E interaction was detected... - Comparison between omega-3 and omega-6 polyunsaturated fatty acid intakes as assessed by a food frequency questionnaire and erythrocyte membrane fatty acid composition in young childrenH D Orton
Department of Preventive Medicine and Biometrics, University of Colorado at Denver and Health Sciences Center, Denver, CO 80262, USA
Eur J Clin Nutr 62:733-8. 2008.... - Maternal risk factors for term neonatal seizures: population-based study in Colorado, 1989-2003Deborah A Hall
Department of Neurology, University of Colorado at Denver and Health Sciences Center, 4200 East Ninth Avenue, Denver, CO 80262, USA
J Child Neurol 21:795-8. 2006..Maternal diabetic vasculopathy can also be a contributing factor... - Extreme genetic risk for type 1A diabetesTheresa A Aly
Barbara Davis Center for Childhood Diabetes and Human Medical Genetics Program, University Colorado Health Sciences Center, Aurora, CO 80045, USA
Proc Natl Acad Sci U S A 103:14074-9. 2006..A subset of siblings at extremely high risk for T1D can now be identified at birth for trials to prevent islet autoimmunity... - Genetic and environmental determinants of 25-hydroxyvitamin D and 1,25-dihydroxyvitamin D levels in Hispanic and African AmericansCorinne D Engelman
Department of Population Health Sciences, University of Wisconsin School of Medicine and Public Health, 610 Walnut Street, 1007A WARF, Madison, Wisconsin 53726 2397, USA
J Clin Endocrinol Metab 93:3381-8. 2008..Vitamin D deficiency is associated with many adverse health outcomes, yet little is known about the genetic epidemiology of vitamin D or its metabolites... - Rheumatoid factor seropositivity is inversely associated with oral contraceptive use in women without rheumatoid arthritisShailaja S Bhatia
Department of Preventive Medicine and Biometrics, University of Colorado at Denver and Health Sciences Center, Denver, 4200 East Ninth Avenue, Box B119, Denver, CO 80262, USA
Ann Rheum Dis 66:267-9. 2007..To examine whether oral contraceptive use is associated with the presence of serum rheumatoid factor in women of reproductive age without rheumatoid arthritis... - Increasing incidence of type 1 diabetes in 0- to 17-year-old Colorado youthKendra Vehik
University of Colorado School of Medicine, Denver, Colorado, USA
Diabetes Care 30:503-9. 2007.... 
Maternal diet during pregnancy and islet autoimmunity in offspringMolly M Lamb
Department of Preventive Medicine and Biometrics, University of Colorado at Denver and Health Sciences Center, Denver, CO, USA
Pediatr Diabetes 9:135-41. 2008..The role of prenatal nutritional exposures has not been thoroughly investigated...- Genome-wide linkage of plasma adiponectin reveals a major locus on chromosome 3q distinct from the adiponectin structural gene: the IRAS family studyXiuqing Guo
Medical Genetics Institutes, Cedars Sinai Medical Center, 8700 Beverly Blvd, 665W, Los Angeles, CA 90048, USA
Diabetes 55:1723-30. 2006..Therefore, a quantitative trait locus at 3q27, likely distinct from the APM1 gene, contributes to the variation of plasma adiponectin levels in the Hispanic-American population... - Genetic mapping of disposition index and acute insulin response loci on chromosome 11q. The Insulin Resistance Atherosclerosis Study (IRAS) Family StudyNicholette D Palmer
Department of Biochemistry, Wake Forest University School of Medicine, Winston-Salem, NC 27157, USA
Diabetes 55:911-8. 2006..These detailed genetic analyses provide strong evidence of a DI locus on 11q in African-American pedigrees, with additional suggestive evidence of independent AIR loci in the same region... - Genetic prediction of autoimmunity: initial oligogenic prediction of anti-islet autoimmunity amongst DR3/DR4-DQ8 relatives of patients with type 1A diabetesTheresa A Aly
Barbara Davis Center for Childhood Diabetes, University of Colorado Health Sciences Center, 4200 East 9th Avenue B 140, Denver, CO 80262, USA
J Autoimmun 25:40-5. 2005..These results highlight the multiplicative risk of combined high-risk genotypes at different loci in terms of time to autoantibody and autoimmune disease development... - Rotavirus infection frequency and risk of celiac disease autoimmunity in early childhood: a longitudinal studyLars C Stene
Barbara Davis Center for Childhood Diabetes, University of Colorado School of Medicine, Aurora, Colorado 80045-6511, USA
Am J Gastroenterol 101:2333-40. 2006..CONCLUSIONS: This prospective study provides the first indication that a high frequency of rotavirus infections may increase the risk of celiac disease autoimmunity in childhood in genetically predisposed individuals... - Normal but increasing hemoglobin A1c levels predict progression from islet autoimmunity to overt type 1 diabetes: Diabetes Autoimmunity Study in the Young (DAISY)Lars C Stene
Barbara Davis Center for Childhood Diabetes, University of Colorado School of Medicine, Aurora, CO 80045-6511, USA
Pediatr Diabetes 7:247-53. 2006..4, 95% confidence interval 1.02-1.8, per SD of 1.1 mmol/L). CONCLUSIONS: Normal but increasing Hb1Ac may be useful in early detection of type 1 diabetes, whereas random plasma glucose levels were less predictive... - Genome-wide association: which do you want first: the good news, the bad news, or the good news?Kent D Taylor
Medical Genetics Institute, Cedars Sinai Medical Center, 8700 Beverly Blvd, Suite 665, West Los Angeles, California 90048 1804, USA
Diabetes 56:2844-8. 2007 - Association of TCF7L2 gene polymorphisms with reduced acute insulin response in Hispanic AmericansNicholette D Palmer
Department of Biochemistry, Wake Forest University School of Medicine, Winston Salem, North Carolina 27157, USA
J Clin Endocrinol Metab 93:304-9. 2008..Genetic variation at the transcription factor 7-like 2 locus has been linked to type 2 diabetes in predominantly European-derived populations. The biological basis of these associations remains to be determined... - Genetic epidemiology of insulin resistance and visceral adiposity. The IRAS Family Study design and methodsLeora Henkin
Wake Forest University School of Medicine, Winston Salem, NC 27157, USA
Ann Epidemiol 13:211-7. 2003..In this report, we describe the methods of the IRAS Family Study, which was designed to identify the genetic and environmental risk factors for insulin resistance and visceral adiposity... - The PPARgamma Pro12Ala polymorphism is not associated with body mass index or waist circumference among Hispanics from ColoradoTracy L Nelson
Department of Health and Exercise Science, Colorado State University, Fort Collins, CO 80523, USA
Ann Nutr Metab 51:252-7. 2007.... - HLA-DPB1*0402 protects against type 1A diabetes autoimmunity in the highest risk DR3-DQB1*0201/DR4-DQB1*0302 DAISY populationErin E Baschal
Barbara Davis Center for Childhood Diabetes, University of Colorado Health Sciences Center, Aurora, CO 80045 6511, USA
Diabetes 56:2405-9. 2007.... - Mortality from pulmonary fibrosis increased in the United States from 1992 to 2003Amy L Olson
Division of Pulmonary Sciences and Critical Care Medicine, University of Colorado Health Sciences Center, Denver Colorado 80262, USA
Am J Respir Crit Care Med 176:277-84. 2007..From the late 1970s to the early 1990s, studies found that mortality rates for pulmonary fibrosis were increasing. Recent data for mortality from pulmonary fibrosis are unavailable... - Quantitative trait analysis of type 2 diabetes susceptibility loci identified from whole genome association studies in the Insulin Resistance Atherosclerosis Family StudyNicholette D Palmer
Department of Biochemistry, Wake Forest University School of Medicine, Winston Salem, NC 27157, USA
Diabetes 57:1093-100. 2008.... - Trends in high-risk HLA susceptibility genes among Colorado youth with type 1 diabetesKendra Vehik
University of Colorado Denver, School of Medicine, Denver, Colorado, USA
Diabetes Care 31:1392-6. 2008.... - Associations of adiponectin with body fat distribution and insulin sensitivity in nondiabetic Hispanics and African-AmericansAnthony J G Hanley
Department of Nutritional Sciences, University of Toronto, Toronto, Ontario, Canada M5S 3E2
J Clin Endocrinol Metab 92:2665-71. 2007.... - VDR and SRD5A2 polymorphisms combine to increase risk for prostate cancer in both non-Hispanic White and Hispanic White menKathleen C Torkko
Department of Pathology, University of Colorado Denver, Anschutz Medical Campus, Aurora, Colorado 80045, USA
Clin Cancer Res 14:3223-9. 2008..This study tested the interactions of VDR (CDX2, FokI) and SRD5A2 (V89L, A49T) polymorphisms, and their associations with prostate cancer... - Perinatal and early childhood risk factors associated with rheumatoid factor positivity in a healthy paediatric populationKendra A Young
Department of Preventive Medicine and Biometrics, University of Colorado at Denver and Health Sciences Center, 4200 East Ninth Avenue, Box B119, Denver, CO 80262, USA
Ann Rheum Dis 66:179-83. 2007..To examine perinatal and childhood risk factors for the presence of rheumatoid factor in healthy children... - Association of proopiomelanocortin gene polymorphisms with obesity in the IRAS family studyBeth S Sutton
Department of Biochemistry, Wake Forest University School of Medicine, Medical Center Boulevard, Winston Salem, NC 27157, USA
Obes Res 13:1491-8. 2005..These results support the hypothesis that POMC contributes genetically to the development of obesity... - Newborn HLA-DR,DQ genotype screening: age- and ethnicity-specific type 1 diabetes risk estimatesLisa M Emery
Department of Preventive Medicine and Biometrics, University of Colorado Health Sciences Center, Denver, CO, USA
Pediatr Diabetes 6:136-44. 2005..To characterize the role of the HLA-DR,DQ genotype and ethnicity on the onset age of T1DM, we analyzed these factors in patients with T1DM and the general population... - Association of non-HLA genes with type 1 diabetes autoimmunityAndrea K Steck
Barbara Davis Center for Childhood Diabetes, University of Colorado Health Sciences Center, Mail Stop A140, P O Box 6511, Aurora, CO 80045 6511, USA
Diabetes 54:2482-6. 2005..Genes involved in the IL-4 regulatory pathway (IL-4, IL-4R, IL-13) may confer susceptibility or protection to type 1 diabetes depending on individual SNPs or specific haplotypes... - Clinical features of children with screening-identified evidence of celiac diseaseEdward J Hoffenberg
Department of Pediatrics, Children s Hospital, and the University of Colorado School of Medicine, Denver, Colorado, USA
Pediatrics 113:1254-9. 2004..However, the clinical significance of a positive test remains uncertain. The objective of this study was to evaluate growth and clinical features of children who test positive for an autoantibody associated with CD... - Linkage of the metabolic syndrome to 1q23-q31 in Hispanic families: the Insulin Resistance Atherosclerosis Study Family StudyCarl D Langefeld
Department of Public Health Sciences, Wake Forest University Health Sciences, Winston Salem, North Carolina 27157 1063, USA
Diabetes 53:1170-4. 2004..These results contribute to the growing evidence that chromosome 1q harbors at least one locus related to the metabolic precursors of diabetes... - Is presence of islet autoantibodies at birth associated with development of persistent islet autoimmunity? The Diabetes Autoimmunity Study in the Young (DAISY)Heather M Stanley
Department of Preventive Medicine and Biometrics, University of Colorado Health Sciences Center, Denver, Colorado 80262, USA
Diabetes Care 27:497-502. 2004..To determine whether the presence of islet autoantibodies in the umbilical cord blood is predictive of subsequent development of islet autoimmunity... - In utero dietary exposures and risk of islet autoimmunity in childrenCarolyn M Fronczak
Department of Preventive Medicine and Biometrics, University of Colorado Health Sciences Center, Denver, Colorado, USA
Diabetes Care 26:3237-42. 2003..CONCLUSIONS: Our findings suggest that maternal intake of vitamin D through food during pregnancy may have a protective effect on the appearance of IA in offspring... - Symptoms of common maternal infections in pregnancy and risk of islet autoimmunity in early childhoodLars C Stene
Barbara Davis Center for Childhood Diabetes, University of Colorado Health Sciences Center, Denver, Colorado 80262, USA
Diabetes Care 26:3136-41. 2003..CONCLUSIONS: Symptoms of maternal infections in pregnancy predicted a significantly lower risk of islet autoimmunity in young girls, suggesting a protective effect of such infections... - A prospective study of the incidence of childhood celiac diseaseEdward J Hoffenberg
Department of Pediatrics, Barbara Davis Center for Childhood Diabetes, University of Colorado, Denver, USA
J Pediatr 143:308-14. 2003..00-10.9, P=.048). Evidence of CD was not observed before age 2.6 years. CONCLUSIONS: Celiac disease may affect 0.9% of Denver children by 5 years of age. Children positive for the HLA-DR3 allele and females appear to be at increased risk... - Insulin sensitivity, insulin secretion, and abdominal fat: the Insulin Resistance Atherosclerosis Study (IRAS) Family StudyLynne E Wagenknecht
Department of Public Health Sciences, Wake Forest University School of Medicine, Winston Salem, North Carolina 27157, USA
Diabetes 52:2490-6. 2003..The fat measures explained 27% of the model R2 for SI, 16% for AIR, and 16% for DI. Thus, fat distribution is an important determinant of both insulin resistance and insulin secretion... - Minimal model-based insulin sensitivity has greater heritability and a different genetic basis than homeostasis model assessment or fasting insulinRichard N Bergman
Keck School of Medicine, University of Southern California, Los Angeles, California, USA
Diabetes 52:2168-74. 2003..Thus S(I), a direct measure of insulin sensitivity, is determined more by genetic factors rather than measures such as HOMA, which reflect fasting insulin... - Risk factors for initial acquisition of Pseudomonas aeruginosa in children with cystic fibrosis identified by newborn screeningJudith H Maselli
Department of Preventive Medicine and Biometrics, University of Colorado Health Sciences Center, Denver, Colorado 80218, USA
Pediatr Pulmonol 35:257-62. 2003..We conclude that female gender, homozygous DeltaF508 mutation, and S. aureus isolations are important risk factors for early P. aeruginosa detection in children with CF identified through newborn screening... - Prospective study of enteroviral infections and development of beta-cell autoimmunity. Diabetes autoimmunity study in the young (DAISY)Patricia M Graves
Department of Preventive Medicine and Biometrics, University of Colorado Health Sciences Center, Denver, CO 80262, USA
Diabetes Res Clin Pract 59:51-61. 2003..Further study is needed to assess whether persistent or repeated EV infections occur frequently in individuals with beta-cell autoimmunity... - Millennium award recipient contribution. Identification of children with early onset and high incidence of anti-islet autoantibodiesDavid T Robles
Barbara Davis Center, Department of Immunology, University of Colorado, Denver, Colorado 80262, USA
Clin Immunol 102:217-24. 2002..These results suggest that a high incidence and early appearance of islet autoantibodies for siblings of patients with type 1A diabetes are associated with DR3/4, DQB1*0302 and potentially increased with HLA-A genotype A1, A2... - Clinical characteristics of children diagnosed with type 1 diabetes through intensive screening and follow-upJennifer M Barker
Barbara Davis Center for Childhood Diabetes, University of Colorado Health Sciences Center, 4200 East Ninth Ave, Box B140, Denver, CO 80262
Diabetes Care 27:1399-404. 2004..The objective of this study was to determine whether earlier diagnosis of diabetes in prospectively followed autoantibody-positive children lowered onset morbidity and improved the clinical course after diagnosis... - A genome scan for fasting insulin and fasting glucose identifies a quantitative trait locus on chromosome 17p: the insulin resistance atherosclerosis study (IRAS) family studyStephen S Rich
Department of Public Health Sciences, Wake Forest University School of Medicine, 3rd Floor MRI Center, Winston Salem, NC 27157, USA
Diabetes 54:290-5. 2005..Identifying genes in these regions should provide insight into the nature of genetic factors regulating plasma glucose and insulin concentrations... - Genetic analysis of adiponectin and obesity in Hispanic families: the IRAS Family StudyBeth S Sutton
Department of Biochemistry, Wake Forest University School of Medicine, Medical Center Blvd, Winston-Salem, NC 27157, USA
Hum Genet 117:107-18. 2005..Additional studies are needed to confirm our findings and determine which polymorphism causes the functional effect... - Association of protein tyrosine phosphatase 1B gene polymorphisms with measures of glucose homeostasis in Hispanic Americans: the insulin resistance atherosclerosis study (IRAS) family studyNicholette D Palmer
Department of Biochemistry, Wake Forest University School of Medicine, Winston Salem, NC 27157, USA
Diabetes 53:3013-9. 2004..001) fasting glucose, respectively, in the IRASFS. This comprehensive genetic analysis of PTPN1 reveals significant association with metabolic traits consistent with the proposed in vivo role for the PTP-1B protein... - Association analysis of the plasminogen activator inhibitor-1 4G/5G polymorphism in Hispanics and African Americans: the IRAS family studyJeannette T Bensen
Center for Human Genomics, Department of Internal Medicine, Wake Forest University School of Medicine, Winston Salem, NC, USA
Hum Hered 57:128-37. 2004..In addition, we explore whether transforming growth factor (TGF-beta1), a key regulator of PAI-1 expression, modifies the influence of the PAI-1 4G/5G polymorphism on these traits... - Prediction of autoantibody positivity and progression to type 1 diabetes: Diabetes Autoimmunity Study in the Young (DAISY)Jennifer M Barker
Barbara Davis Center for Childhood Diabetes, University of Colorado Health Sciences Center, Denver, Colorado 80262, USA
J Clin Endocrinol Metab 89:3896-902. 2004..Predictive value of autoantibodies increases with blinded duplicate and independent sample retesting and incorporation of the level of autoantibody in the predictive algorithm... - Perinatal factors and development of islet autoimmunity in early childhood: the diabetes autoimmunity study in the youngLars C Stene
Barbara Davis Center for Childhood Diabetes, University of Colorado Health Sciences Center, Denver, CO 80262, USA
Am J Epidemiol 160:3-10. 2004..008. Other factors evaluated were not related to risk of islet autoimmunity. In conclusion, influences in utero or during delivery may affect the fetal immune system... - Insulin sensitivity, body fat distribution, and family diabetes history: the IRAS Family StudyBraxton D Mitchell
University of Maryland School of Medicine, Division of Endocrinology, Diabetes, and Nutrition, 660 W Redwood Street, Room 492, Baltimore, MD 21201, USA
Obes Res 12:831-9. 2004..Whether diabetes family history (FH) also predicts visceral fat accumulation and, if so, whether the increased insulin resistance in relatives of diabetic subjects occurs independently of visceral fat accumulation are not known... - Cosegregation of albuminuria and blood pressure: the Insulin Resistance Atherosclerosis (IRAS) family studyXiuqing Guo
Cedars Sinai Medical Center, Los Angeles, California 90048, USA
Am J Hypertens 18:823-7. 2005..Our aim in this study was to examine the familial aggregation of albuminuria and its phenotypic, genetic, and environmental correlations with BP in nondiabetic individuals of Hispanic (HA) and African American (AA) ethnicity... - Antibodies against cyclic citrullinated peptide are associated with HLA-DR4 in simplex and multiplex polyarticular-onset juvenile rheumatoid arthritisElizabeth D Ferucci
Division of Rheumatology, University of Colorado Health Sciences Center, 4200 East Ninth Avenue, Denver, CO 80262, USA
Arthritis Rheum 52:239-46. 2005..Anti-CCP antibodies in JRA are associated with polyarticular onset, a polyarticular course, and erosive disease... - Validation of a food frequency questionnaire in preschool childrenLezlie A Parrish
Department of Preventive Medicine and Biometrics, University of Colorado Health Sciences Center, Denver 80262, USA
Epidemiology 14:213-7. 2003..In addition, the validity of the FFQ using parental report does not appear to be compromised when there are meal providers in addition to the parents... - Does accounting for gene-environment (GxE) interaction increase the power to detect the effect of a gene in a multifactorial disease?Hana Selinger-Leneman
INSERM U535, Le Kremlin Bicetre, France
Genet Epidemiol 24:200-7. 2003..1, accounting for GxE interaction increases the power to detect the gene effect in 200 trios by 10%; alternatively, when the exposure frequency is 0.9, it decreases the power by 15%... - Urinary F2-isoprostanes in young healthy children at risk for type 1 diabetes mellitusLaura D Kauffman
Department of Preventive Medicine and Biometrics, University of Colorado Health Sciences Center, Denver, CO 80262, USA
Free Radic Biol Med 35:551-7. 2003..Normal values in this healthy population can be used as the basis for future studies of disease mechanisms involving oxidative stress... - Comparison of children's diets as reported by the child via the Youth/Adolescent Questionnaire and the parent via the Willett food-frequency questionnaireMolly M Lamb
University of Colorado at Denver and Health Sciences Center, 4200 East 9th Avenue, Denver, CO 80262, USA
Public Health Nutr 10:663-70. 2007..A comparison of a parent-completed Willett food-frequency questionnaire (FFQ) and a self-completed Youth/Adolescent Questionnaire (YAQ) has not yet been conducted... - Identification of quantitative trait loci for glucose homeostasis: the Insulin Resistance Atherosclerosis Study (IRAS) Family StudyStephen S Rich
Department of Public Health Sciences, Wake Forest University School of Medicine, 3rd Floor, MRI Center, Winston Salem, NC 27157, USA
Diabetes 53:1866-75. 2004.... - Association of the peroxisome proliferator-activated receptor gamma gene with type 2 diabetes mellitus varies by physical activity among non-Hispanic whites from ColoradoTracy L Nelson
Department of Health and Exercise Science, Colorado State University, Fort Collins, CO 80523, USA
Metabolism 56:388-93. 2007..37; 95% confidence interval, 1.14-4.94). There may be a gene-environment interaction between the Pro12 allele of the PPAR-gamma gene and physical activity that results in increased risk of T2DM in NHWs... - Plasma micronutrients are associated with dietary intake and environmental tobacco smoke exposure in a paediatric populationHeather Brady
Department of Preventive Medicine and Biometrics, University of Colorado Denver and Health Sciences Center UCDHSC, and Section of Pediatric Gastroenterology, Hepatology, and Nutrition, The Children s Hospital, Denver, CO 80262, USA
Public Health Nutr 10:712-8. 2007..While adult populations have been well described in terms of nutritional status, such as the concentration of nutrient biomarkers, little work has been done in healthy paediatric populations...
Research Grants
- Nutritional Etiology of Pre-Diabetic AutoimmunityJill Norris; Fiscal Year: 2005..In addition, we propose to examine the role of n-3 and n-6 PUFA, prostaglandins, erythrocyte membrane fatty acids, and prostaglandin synthase 2 (PGS2 ) expression in the remission of beta cell autoimmunity. ..
- NUTRITIONAL ETIOLOGY OF PREDIABETIC AUTOIMMUNITYJill Norris; Fiscal Year: 2007....
- GENETICS OF ADIPOSITY AND GLUCOSE HOMEOSTASISJill Norris; Fiscal Year: 2009....
- RA-Related Autoantibodies in Healthy FDR of RA PatientsJill Norris; Fiscal Year: 2009....
- NUTRITIONAL ETIOLOGY OF PREDIABETIC AUTOIMMUNITYJill Norris; Fiscal Year: 2009....
- IRAS FAMILY STUDY--GENETICS OF INSULIN RESISTANCEJill Norris; Fiscal Year: 2003..This project will contribute substantially to our understanding of the genetic determinants of insulin sensitivity, and consequently to risk of atherosclerosis. ..
- NUTRITIONAL ETIOLOGY OF PREDIABETIC AUTOIMMUNITYJill Norris; Fiscal Year: 2000....
- GENE ENVIRONMENT STUDY OF TYPE 2 DIABETES IN FAMILIESJill Norris; Fiscal Year: 2002....
- NUTRITIONAL ETIOLOGY OF PREDIABETIC AUTOIMMUNITYJill M Norris; Fiscal Year: 2010....