Research Topics
Genomes and Genes | Sandra NormanSummaryAffiliation: University of Pennsylvania Country: USA Publications
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Publications
Risk factors for lymphedema after breast cancer treatmentSandra A Norman
Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania, Philadelphia, PA 19104 6021, USA
Cancer Epidemiol Biomarkers Prev 19:2734-46. 2010..As cancer treatments evolve, it is important to reevaluate their effect on lymphedema risk in breast cancer survivors...
Hormone therapy and fatal breast cancerSandra A Norman
Department of Biostatistics and Epidemiology, University of Pennsylvania, Philadelphia, PA 19104 6021, USA
Pharmacoepidemiol Drug Saf 19:440-7. 2010..Using a population-based case-control design, we estimated incidence rate ratios of fatal breast cancer in postmenopausal hormone therapy (HT) users compared to non-users by type, duration, and recency of HT use...
Lymphedema in breast cancer survivors: incidence, degree, time course, treatment, and symptomsSandra A Norman
Department of Medicine, Division of Hematology Oncology, Center for Clinical Epidemiologyand Biostatistics, University of Pennsylvania School of Medicine, Philadelphia, PA 19104 6021, USA
J Clin Oncol 27:390-7. 2009..To examine the incidence, degree, time course, treatment, and symptoms of lymphedema in breast cancer survivors...
Protection of mammography screening against death from breast cancer in women aged 40-64 yearsSandra A Norman
Center for Clinical Epidemiology and Biostatistics and Department of Biostatistics and Epidemiology, University of Pennsylvania, 801 Blockley Hall, 423 Guardian Drive, Philadelphia, PA 19104 6021, USA
Cancer Causes Control 18:909-18. 2007..This study assessed the efficacy of community-based screening mammography in protecting against breast cancer death, asking whether age differences in efficacy persisted in the 1990s...
Modifiable risk factors for breast cancer recurrence: what can we tell survivors?Sandra A Norman
Department of Biostatistics and Epidemiology, University of Pennsylvania, Philadelphia, Pennsylvania 19104 6021, USA
J Womens Health (Larchmt) 16:177-90. 2007....
Lack of effect modification between estrogen metabolism genotypes and combined hormone replacement therapy in postmenopausal breast cancer riskTimothy R Rebbeck
Department of Biostatistics and Epidemiology, Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania School of Medicine, Philadelphia, PA 19104-6021, USA
Cancer Epidemiol Biomarkers Prev 16:1318-20. 2007
Pairwise combinations of estrogen metabolism genotypes in postmenopausal breast cancer etiologyTimothy R Rebbeck
Department of Biostatistics and Epidemiology, Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania School of Medicine, 904 Blockley Hall, 423 Guardian Drive, Philadelphia, PA 19104 6021, USA
Cancer Epidemiol Biomarkers Prev 16:444-50. 2007....
A retrospective case-control study of the use of hormone-related supplements and association with breast cancerTimothy R Rebbeck
Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania School of Medicine, Philadelphia, PA 19104 6021, USA
Int J Cancer 120:1523-8. 2007..Additional confirmatory studies are required to determine whether black cohosh could be used to prevent breast cancer...
Older age predicts a decline in adjuvant chemotherapy recommendations for patients with breast carcinoma: evidence from a tertiary care cohort of chemotherapy-eligible patientsAngela DeMichele
Division of Hematology Oncology, Department of Medicine, and Abramson Cancer Center, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
Cancer 97:2150-9. 2003....
Benefit of screening mammography in reducing the rate of late-stage breast cancer diagnoses (United States)Sandra A Norman
Center for Clinical Epidemiology and Biostatistics and Department of Biostatistics and Epidemiology, University of Pennsylvania, 801 Blockley Hall, 423 Guardian Drive, Philadelphia, PA 19104 6021, USA
Cancer Causes Control 17:921-9. 2006..We studied the benefit of modern mammography screening in community settings, evaluating age-related differences in rates of late-stage breast cancer detection...
Absence of an effect of injectable and implantable progestin-only contraceptives on subsequent risk of breast cancerBrian L Strom
Center for Clinical Epidemiology and Biostatistics and Department of Biostatistics and Epidemiology, 824 Blockley Hall, 423 Guardian Drive, University of Pennsylvania, Philadelphia, PA 19104 6021, USA
Contraception 69:353-60. 2004..This study does not support an increased risk of breast cancer associated with the use of injectable or implantable progestin-only contraceptives in women aged 35 to 64...
Combined effect of oral contraceptive use and hormone replacement therapy on breast cancer risk in postmenopausal womenSandra A Norman
Center for Clinical Epidemiology and Biostatistics, Department of Biostatistics and Epidemiology, University of Pennsylvania, Philadelphia, PA 19104 6021, USA
Cancer Causes Control 14:933-43. 2003..We examined breast cancer risk related to lifetime exposure to oral contraceptives (OCs) and hormone replacement therapy (HRT) in postmenopausal women...
Validation of self-reported screening mammography histories among women with and without breast cancerSandra A Norman
Center for Clinical Epidemiology and Biostatistics and Department of Epidemiology and Biostatistics, University of Pennsylvania, Philadelphia 19104 6021, USA
Am J Epidemiol 158:264-71. 2003..Therefore, odds ratios will likely be biased toward the null, underestimating screening efficacy...
The intersection of cancer and aging: establishing the need for breast cancer rehabilitationKathryn H Schmitz
Division of Clinical Epidemiology, Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania School of Medicine, 921 Blockley Hall, 423 Guardian Drive, Philadelphia, PA 19104, USA
Cancer Epidemiol Biomarkers Prev 16:866-72. 2007....
Measuring screening intensity in case-control studies of the efficacy of mammographyA Russell Localio
Department of Biostatistics and Epidemiology, Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania School of Medicine, Philadelphia, 19104 6021, USA
Am J Epidemiol 164:272-81. 2006..Assessing the effect of screening intensity in case-control studies of mammography is possible if principles and methods for misclassification and measurement error guide the analysis...
Practical aspects of sharing controls between case-control studiesGreta R Bunin
Center for Clinical Epidemiology and Biostatistics and Department of Biostatistics and Epidemiology, University of Pennsylvania School of Medicine, Philadelphia, PA, USA
Pharmacoepidemiol Drug Saf 14:523-30. 2005..We discuss the practical advantages and challenges of sharing controls among two or more concurrently conducted case-control studies...
Morbidity and mortality of colorectal carcinoma surgery differs by insurance statusRachel Rapaport Kelz
Center for Clinical Epidemiology and Biostatistics, The University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA
Cancer 101:2187-94. 2004....
Lifetime recreational exercise activity and breast cancer risk among black women and white womenLeslie Bernstein
Department of Preventive Medicine, Keck School of Medicine, USC Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, CA 90033, USA
J Natl Cancer Inst 97:1671-9. 2005....
Oral contraceptives and the risk of breast cancerPolly A Marchbanks
Division of Reproductive Health, Centers for Disease Control and Prevention, Atlanta, USA
N Engl J Med 346:2025-32. 2002..CONCLUSIONS: Among women from 35 to 64 years of age, current or former oral-contraceptive use was not associated with a significantly increased risk of breast cancer...
Relation of regimens of combined hormone replacement therapy to lobular, ductal, and other histologic types of breast carcinomaJanet R Daling
Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, USA
Cancer 95:2455-64. 2002..However, the use of combined (estrogen and progestin) hormone replacement therapy (CHRT) also has increased during the last decade and may account in part for the increase in invasive lobular breast carcinoma...
Projecting individualized absolute invasive breast cancer risk in African American womenMitchell H Gail
Division of Cancer Epidemiology and Genetics, National Cancer Institute, Executive Plaza South Rm 8032, Bethesda, MD 20892 7244, USA
J Natl Cancer Inst 99:1782-92. 2007..We developed a model for projecting absolute risk of invasive breast cancer in African American women and compared its projections with those from the Breast Cancer Risk Assessment Tool...
Hormone replacement therapy regimens and breast cancer risk(1)Linda K Weiss
Population Studies and Prevention Program, Karmanos Cancer Institute at Wayne State University, Detroit, Michigan, USA
Obstet Gynecol 100:1148-58. 2002..Progestin administered in an uninterrupted regimen may be a contributing factor. Risk dissipates once use is discontinued...
Do thyroid disorders increase the risk of breast cancer?Michael S Simon
Division of Hematology and Oncology, Karmanos Cancer Institute at Wayne State University, Detroit, Michigan, USA
Cancer Epidemiol Biomarkers Prev 11:1574-8. 2002..There was no statistical interaction between thyroid disorders, thyroid treatments, and race, menopausal status, or parity. We found no association between thyroid disorders or their associated treatments and the risk of breast cancer...
Infertility drugs and the risk of breast cancer: findings from the National Institute of Child Health and Human Development Women's Contraceptive and Reproductive Experiences StudyRonald T Burkman
National Cancer Institute Surveillance, Epidemiology, and End Results Registry, Department of Obstetrics and Gynecology, Henry Ford Health System, Detroit, Michigan, USA
Fertil Steril 79:844-51. 2003..To determine the association between infertility drug use and invasive breast cancer in a population-based case-control study...
Association of regimens of hormone replacement therapy to prognostic factors among women diagnosed with breast cancer aged 50-64 yearsJanet R Daling
Fred Hutchinson Cancer Research Center, Division of Public Health Sciences, Seattle, Washington 98109 1024, USA
Cancer Epidemiol Biomarkers Prev 12:1175-81. 2003....
Reproductive factors and risk of breast carcinoma in a study of white and African-American womenGiske Ursin
Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California 90089, USA
Cancer 101:353-62. 2004....
Risk of breast cancer associated with short-term use of oral contraceptivesSuzanne G Folger
Division of Reproductive Health, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
Cancer Causes Control 18:189-98. 2007..To estimate breast cancer risk associated with short-term (<6 months) oral contraceptive use, and explore variation in estimates by use characteristics and medical, menstrual, and reproductive history...
Prevalence and predictors of BRCA1 and BRCA2 mutations in a population-based study of breast cancer in white and black American women ages 35 to 64 yearsKathleen E Malone
Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA
Cancer Res 66:8297-308. 2006....
Racial differences in the familial aggregation of breast cancer and other female cancersMichael S Simon
Division of Haematology and Oncology, Barbara Ann Karmanos Cancer Institute, 4100 John R, 4221 Hudson, Weber Cancer Research Building, Detroit, M1 48201, USA
Breast Cancer Res Treat 89:227-35. 2005..17 (1.22-3.85). In conclusion, these racially distinct aggregation patterns may reflect different modes of inheritance and/or environmental factors that impact cancer risk...
The NICHD Women's Contraceptive and Reproductive Experiences Study: methods and operational resultsPolly A Marchbanks
Division of Reproductive Health, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
Ann Epidemiol 12:213-21. 2002..5% and 78.6%, respectively, with lower rates for black women and older women. CONCLUSIONS: The methodologic details of this large collaboration may assist researchers conducting similar investigations...
Alcohol exposure and breast cancer: results of the women's contraceptive and reproductive experiences studyJill A McDonald
National Center for Chronic Disease Prevention and Health Promotion, Division of Reproductive Health, 4770 Buford Highway Northeast, MS-K22, Atlanta, GA 30341-3724, USA
Cancer Epidemiol Biomarkers Prev 13:2106-16. 2004..Further work is needed to explain how alcohol exposure, sex hormones, and tumor receptor status interact...
Research Grants
- BREAST CANCER PATTERNS OF CARE AND MORBIDITYSandra Norman; Fiscal Year: 2002....
- BREAST CANCER PATTERNS OF CARE AND MORBIDITYSandra Norman; Fiscal Year: 2007..Preliminary data from the parent study suggest that only longer follow-up can capture the interplay of time-dependent risks, ongoing treatment, and patient characterisitics that occur over a longer period of time. ..
