Shoko Nioka

Summary

Affiliation: University of Pennsylvania
Country: USA

Publications

  1. ncbi request reprint Oxygenation and blood concentration changes in human subject prefrontal activation by anagram solutions
    Britton Chance
    University of Pennsylvania, Department of Biochemistry and Biophysics, Philadelphia, PA 19104 6059, USA
    Adv Exp Med Biol 510:397-401. 2003
  2. ncbi request reprint Fetal transabdominal pulse oximeter studies using a hypoxic sheep model
    Shoko Nioka
    Department of Biochem Biophysics, University of Pennsylvania, PA 19104, USA
    J Matern Fetal Neonatal Med 17:393-9. 2005
  3. ncbi request reprint Breast cancer detection based on incremental biochemical and physiological properties of breast cancers: a six-year, two-site study
    Britton Chance
    University of Pennsylvania, Department of Biochemistry, Philadelphia, 19104 6059, USA
    Acad Radiol 12:925-33. 2005
  4. ncbi request reprint Simulation of Mb/Hb in NIRS and oxygen gradient in the human and canine skeletal muscles using H-NMR and NIRS
    Shoko Nioka
    Dept of Biochemistry and Radiology, University of Pennsylvania, USA
    Adv Exp Med Biol 578:223-8. 2006
  5. ncbi request reprint Effect of errors in baseline optical properties on accuracy of transabdominal near-infrared spectroscopy in fetal sheep brain during hypoxic stress
    Theresa Mawn
    University of Pennsylvania, Department of Bioengineering, Philadelphia, Pennsylvania 19104 6100, USA
    J Biomed Opt 10:064001. 2005
  6. ncbi request reprint Reduced heterogeneity of muscle deoxygenation during heavy bicycle exercise
    Ryotaro Kime
    Department of Biochemistry and Biophysics, University of Pennsylvania, Philadelphia, PA, USA
    Med Sci Sports Exerc 37:412-7. 2005
  7. ncbi request reprint Skeletal muscle energetics with PNMR: personal views and historic perspectives
    Britton Chance
    Department of Biochemistry and Biophysics, University of Pennsylvania, Philadelphia, PA 19104 6059, USA
    NMR Biomed 19:904-26. 2006
  8. doi request reprint Heterogeneity of mitochondrial redox state in premalignant pancreas in a PTEN null transgenic mouse model
    He N Xu
    Department of Radiology, School of Medicine, University of Pennsylvania, Philadelphia, PA, USA
    Adv Exp Med Biol 701:207-13. 2011
  9. ncbi request reprint Modeling of oxygen diffusion and metabolism from capillary to muscle
    Ping Huang
    University of Pennsylvania, Philadelphia, PA 19104, USA
    Adv Exp Med Biol 540:325-30. 2003
  10. ncbi request reprint In vivo continuous-wave optical breast imaging enhanced with Indocyanine Green
    Xavier Intes
    Department of Biochemistry and Biophysics, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
    Med Phys 30:1039-47. 2003

Research Grants

Detail Information

Publications25

  1. ncbi request reprint Oxygenation and blood concentration changes in human subject prefrontal activation by anagram solutions
    Britton Chance
    University of Pennsylvania, Department of Biochemistry and Biophysics, Philadelphia, PA 19104 6059, USA
    Adv Exp Med Biol 510:397-401. 2003
    ..A wearable NIR measurement of metabolic activation and blood flow may be a useful educational aid. In summary, the optical method focuses attention on cognition activated oxygenation of prefrontal cortex...
  2. ncbi request reprint Fetal transabdominal pulse oximeter studies using a hypoxic sheep model
    Shoko Nioka
    Department of Biochem Biophysics, University of Pennsylvania, PA 19104, USA
    J Matern Fetal Neonatal Med 17:393-9. 2005
    ..This study investigates the validity of transabdominal pulse oximetry using a sheep fetal hypoxia model with fetal arterial hemoglobin saturation...
  3. ncbi request reprint Breast cancer detection based on incremental biochemical and physiological properties of breast cancers: a six-year, two-site study
    Britton Chance
    University of Pennsylvania, Department of Biochemistry, Philadelphia, 19104 6059, USA
    Acad Radiol 12:925-33. 2005
    ....
  4. ncbi request reprint Simulation of Mb/Hb in NIRS and oxygen gradient in the human and canine skeletal muscles using H-NMR and NIRS
    Shoko Nioka
    Dept of Biochemistry and Radiology, University of Pennsylvania, USA
    Adv Exp Med Biol 578:223-8. 2006
  5. ncbi request reprint Effect of errors in baseline optical properties on accuracy of transabdominal near-infrared spectroscopy in fetal sheep brain during hypoxic stress
    Theresa Mawn
    University of Pennsylvania, Department of Bioengineering, Philadelphia, Pennsylvania 19104 6100, USA
    J Biomed Opt 10:064001. 2005
    ..Under hypoxic conditions, however, the variability of the NIR StO2 calculations with changes in the assumed reference properties became more significant...
  6. ncbi request reprint Reduced heterogeneity of muscle deoxygenation during heavy bicycle exercise
    Ryotaro Kime
    Department of Biochemistry and Biophysics, University of Pennsylvania, Philadelphia, PA, USA
    Med Sci Sports Exerc 37:412-7. 2005
    ..This study evaluated heterogeneity of muscle O2 dynamics in a single muscle during bicycle exercise using an eight-channel near-infrared continuous wave spectroscopy (NIRcws) mapping system...
  7. ncbi request reprint Skeletal muscle energetics with PNMR: personal views and historic perspectives
    Britton Chance
    Department of Biochemistry and Biophysics, University of Pennsylvania, Philadelphia, PA 19104 6059, USA
    NMR Biomed 19:904-26. 2006
    ..Some of the research has been introduced in exercise physiology. Future directions of NMR on bioenergetics, as a part of system biological approaches, are indicated...
  8. doi request reprint Heterogeneity of mitochondrial redox state in premalignant pancreas in a PTEN null transgenic mouse model
    He N Xu
    Department of Radiology, School of Medicine, University of Pennsylvania, Philadelphia, PA, USA
    Adv Exp Med Biol 701:207-13. 2011
    ....
  9. ncbi request reprint Modeling of oxygen diffusion and metabolism from capillary to muscle
    Ping Huang
    University of Pennsylvania, Philadelphia, PA 19104, USA
    Adv Exp Med Biol 540:325-30. 2003
  10. ncbi request reprint In vivo continuous-wave optical breast imaging enhanced with Indocyanine Green
    Xavier Intes
    Department of Biochemistry and Biophysics, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
    Med Phys 30:1039-47. 2003
    ..These results provide further evidence that in vivo pharmacokinetics of ICG in breast tumors may be a useful diagnostic tool for differentiation of benign and malignant pathologies...
  11. pmc Quantitative mitochondrial redox imaging of breast cancer metastatic potential
    He N Xu
    University of Pennsylvania, School of Medicine, Department of Radiology, B6 Blockley Hall, 423 Guardian Drive, Philadelphia, Pennsylvania 19104 6069, USA
    J Biomed Opt 15:036010. 2010
    ..Mitochondrial redox imaging can be clinically implemented utilizing cryogenic biopsy specimens and is useful for drug development and for clinical diagnosis of breast cancer...
  12. ncbi request reprint Noninvasive diffuse optical measurement of blood flow and blood oxygenation for monitoring radiation therapy in patients with head and neck tumors: a pilot study
    Ulas Sunar
    Department of Physics and Astronomy, University of Pennsylvania, Philadelphia, Pennsylvania 19104 6396, USA
    J Biomed Opt 11:064021. 2006
    ..0+/-8.1) [microM] at the end of the fourth week of therapy. These preliminary results suggest daily diffuse-optics-based therapy monitoring is feasible during the first two weeks and may have clinical promise...
  13. ncbi request reprint Quantitative brain tissue oximetry, phase spectroscopy and imaging the range of homeostasis in piglet brain
    Britton Chance
    Department of Biochemistry and Biophysics, Johnson Research Foundation, University of Pennsylvania, Center for Biomedical Optics, University City Science Center, Philadelphia, PA, USA
    Adv Exp Med Biol 530:13-8. 2003
    ..Beyond that range, the tissue oxygen is still correctly measured but, as expected, approaches the arterial saturation at low metabolic rates and the venous saturation at high metabolic rates of mitochondria...
  14. ncbi request reprint A wearable brain imager
    Britton Chance
    Department of Biochemistry and Biophysics, University of Pennsylvania, Philadelphia 19104 6059, USA
    IEEE Eng Med Biol Mag 26:30-7. 2007
  15. ncbi request reprint Relationship between muscle architectural features and oxygenation status determined by near infrared device
    Hajime Miura
    Department of Biochemistry and Biophysics, School of Medicine, University of Pennsylvania, PA 19104, Philadelphia, USA
    Eur J Appl Physiol 91:273-8. 2004
    ..05), between DeltaNIR-blood volume and Deltafascicle angle ( r=-0.85, P<0.05). In conclusion, the plantar flexion exercise produced regional differences in oxygenation status consistent with regional differences in muscle architecture...
  16. ncbi request reprint Mitochondrial NADH as the bellwether of tissue O2 delivery
    Britton Chance
    Adv Exp Med Biol 566:231-42. 2005
    ....
  17. doi request reprint Pharmacokinetic-rate images of indocyanine green for breast tumors using near-infrared optical methods
    Burak Alacam
    Department of Electrical, Computer, and Systems Engineering, Rensselaer Polytechnic Institute, Troy, NY, USA
    Phys Med Biol 53:837-59. 2008
    ..Our study indicates that the pharmacokinetic-rate images may provide superior information than single set of pharmacokinetic rates estimated from the entire breast tissue for breast cancer diagnosis...
  18. ncbi request reprint Characterization of breast tumors with NIR methods using optical indices
    Burak Alacam
    Dept of Electrical, Computer, and Systems Engineering, Rensselaer Polytechnic Institute, Troy, NY 12180, USA
    Conf Proc IEEE Eng Med Biol Soc 2007:5186-9. 2007
    ..91 with a significance level of 0.05. Our results suggest that the features, relative blood concentration, and oxygen saturation can differentiate breast tumors with a relatively high precision...
  19. ncbi request reprint Reconstruction of spatially resolved pharmacokinetic rate images of fluorescence agents in FDOT
    Burak Alacam
    Dept of Electrical Computer and Systems Engineering, Rensselaer Polytechnic Institute, Troy, New York 19102, USA
    Conf Proc IEEE Eng Med Biol Soc 1:5627-30. 2006
    ....
  20. ncbi request reprint Comparison of low- and high-intensity resistance exercise on lipid peroxidation: role of muscle oxygenation
    Jay R Hoffman
    College of New Jersey, Ewing 08628, USA
    J Strength Cond Res 21:118-22. 2007
    ..44). Results suggest that increases in MDA occur independently of exercise intensity, but tissue acidosis may have a larger influence on MDA formation...
  21. ncbi request reprint The effect of a competitive collegiate football season on power performance and muscle oxygen recovery kinetics
    Jay R Hoffman
    The College of New Jersey, Ewing, New Jersey 08628, USA
    J Strength Cond Res 19:509-13. 2005
    ..Results indicate that the extent of muscle deoxygenation is reduced during high-intensity exercise and that muscle oxygen recovery kinetics improves over the duration of a competitive season of football...
  22. ncbi request reprint Transabdominal fetal pulse oximetry with near-infrared spectroscopy
    Anthony M Vintzileos
    Department of Obstetrics, Gynecology and Reproductive Sciences, UMDNJ Robert Wood Johnson Medical School, New Brunswick, NJ, USA
    Am J Obstet Gynecol 192:129-33. 2005
    ..The purpose of this study was to determine the feasibility of noninvasive fetal pulse oximetry in the human fetus with transabdominal continuous-wave near-infrared spectroscopy...
  23. ncbi request reprint Effect of muscle oxygenation during resistance exercise on anabolic hormone response
    Jay R Hoffman
    The College of New Jersey, Ewing, NJ 08628, USA
    Med Sci Sports Exerc 35:1929-34. 2003
    ..This investigation examined the affects of two different resistance exercise protocols on muscle oxygenation, and the anabolic hormonal response to such exercise...
  24. ncbi request reprint Simulation study of breast tissue hemodynamics during pressure perturbation
    Shoko Nioka
    Adv Exp Med Biol 566:17-22. 2005
    ..The results showed that simulation can be used to obtain venous and average oxygen saturation as well as blood flow in compressed breast tissues...
  25. ncbi request reprint Evaluation of physiological responses during recovery following three resistance exercise programs
    Jie Kang
    The College of New Jersey, Ewing, New Jersey 08628, USA
    J Strength Cond Res 19:305-9. 2005
    ..In addition, an exercise routine performed at low to moderate intensity coupled with a moderate to high exercise volume is most effective in maximizing caloric expenditure following resistance exercise...

Research Grants2

  1. Hand-Held Phased Array:Localization of Molecular Beacons
    Shoko Nioka; Fiscal Year: 2004
    ..therefore, technical transfer has already been outlined and a wide market may be established. ..
  2. High Resolution 3-D Imaging of Molecular Beacons
    Shoko Nioka; Fiscal Year: 2004
    ..abstract_text> ..