V L Nimgaonkar

Summary

Affiliation: University of Pittsburgh
Country: USA

Publications

  1. pmc Neurotropic infectious agents and cognitive impairment in schizophrenia
    Vishwajit L Nimgaonkar
    Department of Psychiatry, University of Pittsburgh School of Medicine, Western Psychiatric Institute and Clinic, Pittsburgh, PA, USA
    Schizophr Bull 38:1135-6. 2012
  2. pmc Evaluation of HLA polymorphisms in relation to schizophrenia risk and infectious exposure
    Mikhil Bamne
    Department of Psychiatry, University of Pittsburgh School of Medicine, Western Psychiatric Institute and Clinic, Pittsburgh, PA, USA
    Schizophr Bull 38:1149-54. 2012
  3. pmc Exposure to herpes simplex virus type 1 and cognitive impairments in individuals with schizophrenia
    Konasale M Prasad
    Department of Psychiatry, University of Pittsburgh School of Medicine, Western Psychiatric Institute and Clinic, Pittsburgh, PA 15213, USA
    Schizophr Bull 38:1137-48. 2012
  4. ncbi request reprint Negative association of schizophrenia with HLA DQB1*0602: evidence from a second African-American cohort
    V L Nimgaonkar
    Department of Psychiatry, University of Pittsburgh, School of Medicine, PA, USA
    Schizophr Res 23:81-6. 1997
  5. ncbi request reprint DNA pooling: a comprehensive, multi-stage association analysis of ACSL6 and SIRT5 polymorphisms in schizophrenia
    K V Chowdari
    Department of Psychiatry, University of Pittsburgh, Pittsburgh, PA 15213, USA
    Genes Brain Behav 6:229-39. 2007
  6. ncbi request reprint Association study of eight circadian genes with bipolar I disorder, schizoaffective disorder and schizophrenia
    H A Mansour
    Departments of Psychiatry and Human Genetics, University of Pittsburgh School of Medicine, Western Psychiatric Institute and Clinic, PA, USA
    Genes Brain Behav 5:150-7. 2006
  7. ncbi request reprint Dopamine receptor genetic variation, psychosis, and aggression in Alzheimer disease
    R A Sweet
    Department of Psychiatry, University of Pittsburgh School of Medicine, PA, USA
    Arch Neurol 55:1335-40. 1998
  8. ncbi request reprint Association studies of cytosolic phospholipase A2 polymorphisms and schizophrenia among two independent family-based samples
    K V Chowdari
    Department of Psychiatry, University of Pittsburgh School of Medicine and Graduate School of Public Health, Pittsburgh, Pennsylvania, USA
    Psychiatr Genet 11:207-12. 2001
  9. ncbi request reprint Low prevalence of psychoses among the Hutterites, an isolated religious community
    V L Nimgaonkar
    Department of Psychiatry, University of Pittsburgh School of Medicine, PA, USA
    Am J Psychiatry 157:1065-70. 2000
  10. ncbi request reprint Linkage analysis of Alzheimer disease with psychosis
    S A Bacanu
    Department of Psychiatry, University of Pittsburgh, School of Medicine, PA, USA
    Neurology 59:118-20. 2002

Collaborators

Detail Information

Publications21

  1. pmc Neurotropic infectious agents and cognitive impairment in schizophrenia
    Vishwajit L Nimgaonkar
    Department of Psychiatry, University of Pittsburgh School of Medicine, Western Psychiatric Institute and Clinic, Pittsburgh, PA, USA
    Schizophr Bull 38:1135-6. 2012
    ..The present theme issue evaluates epidiagnostic cognitive effects of two common infectious agents, namely Herpes Simplex Virus, type 1 and Toxoplasma gondii...
  2. pmc Evaluation of HLA polymorphisms in relation to schizophrenia risk and infectious exposure
    Mikhil Bamne
    Department of Psychiatry, University of Pittsburgh School of Medicine, Western Psychiatric Institute and Clinic, Pittsburgh, PA, USA
    Schizophr Bull 38:1149-54. 2012
    ..3-22.1, the human leukocyte antigen (HLA) region, as common risk factors for schizophrenia (SZ). Other studies implicate viral and protozoan exposure. Our study tests chromosome 6p SNPs for effects on SZ risk with and without exposure...
  3. pmc Exposure to herpes simplex virus type 1 and cognitive impairments in individuals with schizophrenia
    Konasale M Prasad
    Department of Psychiatry, University of Pittsburgh School of Medicine, Western Psychiatric Institute and Clinic, Pittsburgh, PA 15213, USA
    Schizophr Bull 38:1137-48. 2012
    ..These studies are reviewed critically and further lines of enquiry recommended. The results are important from a public health perspective, as HSV1 exposure is highly prevalent in many populations...
  4. ncbi request reprint Negative association of schizophrenia with HLA DQB1*0602: evidence from a second African-American cohort
    V L Nimgaonkar
    Department of Psychiatry, University of Pittsburgh, School of Medicine, PA, USA
    Schizophr Res 23:81-6. 1997
    ..48; 95% CI: 0.12, 0.52). The present findings support and association between schizophrenia and the HLA DQB1 gene locus among African-Americans...
  5. ncbi request reprint DNA pooling: a comprehensive, multi-stage association analysis of ACSL6 and SIRT5 polymorphisms in schizophrenia
    K V Chowdari
    Department of Psychiatry, University of Pittsburgh, Pittsburgh, PA 15213, USA
    Genes Brain Behav 6:229-39. 2007
    ..This strategy may be particularly useful for research groups lacking access to high throughput genotyping facilities. Our analyses did not yield convincing evidence for associations of schizophrenia with ACSL6 or SIRT5...
  6. ncbi request reprint Association study of eight circadian genes with bipolar I disorder, schizoaffective disorder and schizophrenia
    H A Mansour
    Departments of Psychiatry and Human Genetics, University of Pittsburgh School of Medicine, Western Psychiatric Institute and Clinic, PA, USA
    Genes Brain Behav 5:150-7. 2006
    ..Thus far, evidence for association between specific SNPs at the circadian gene loci and BD1 is tentative. Additional studies using larger samples are required to evaluate the associations reported here...
  7. ncbi request reprint Dopamine receptor genetic variation, psychosis, and aggression in Alzheimer disease
    R A Sweet
    Department of Psychiatry, University of Pittsburgh School of Medicine, PA, USA
    Arch Neurol 55:1335-40. 1998
    ..To examine if selected polymorphisms in the dopamine receptor genes DRD1, DRD2, DRD3, and DRD4 are associated with the presence of psychosis or aggressive behavior in patients with Alzheimer disease (AD)...
  8. ncbi request reprint Association studies of cytosolic phospholipase A2 polymorphisms and schizophrenia among two independent family-based samples
    K V Chowdari
    Department of Psychiatry, University of Pittsburgh School of Medicine and Graduate School of Public Health, Pittsburgh, Pennsylvania, USA
    Psychiatr Genet 11:207-12. 2001
    ..In an attempt to replicate these results, two independent family-based samples were ascertained from the United States and India (86 and 159 families, respectively). No significant associations were detected in either sample...
  9. ncbi request reprint Low prevalence of psychoses among the Hutterites, an isolated religious community
    V L Nimgaonkar
    Department of Psychiatry, University of Pittsburgh School of Medicine, PA, USA
    Am J Psychiatry 157:1065-70. 2000
    ..The study stemmed from an earlier epidemiological survey of North American Hutterite colonies (1950-1953), in which a low prevalence of psychoses was documented...
  10. ncbi request reprint Linkage analysis of Alzheimer disease with psychosis
    S A Bacanu
    Department of Psychiatry, University of Pittsburgh, School of Medicine, PA, USA
    Neurology 59:118-20. 2002
    ..Linkage analysis of families with LOAD+P identified one significant and several suggestive novel linkage signals, which bolsters the conjecture of greater etiologic homogeneity...
  11. doi request reprint Candidate genes and their interactions with other genetic/environmental risk factors in the etiology of schizophrenia
    K M Prasad
    Department of Psychiatry, University of Pittsburgh School of Medicine, 3811 O Hara Street, Pitsburgh, PA 15213, United States
    Brain Res Bull 83:86-92. 2010
    ..By way of example, we summarize our ongoing analyses of dopaminergic polymorphisms, as well as infectious etiological factors in schizophrenia genesis...
  12. ncbi request reprint Psychotic symptoms in Alzheimer disease: evidence for a distinct phenotype
    R A Sweet
    Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, PA 15231, USA
    Mol Psychiatry 8:383-92. 2003
    ..We discuss possible genetic models of psychotic symptoms in AD, and suggest strategies for further investigation. Identification of such genetic factors may facilitate gene-mapping studies for both AD and idiopathic psychoses...
  13. ncbi request reprint Brain morphological changes associated with exposure to HSV1 in first-episode schizophrenia
    K M R Prasad
    Department of Psychiatry, Western Psychiatric Institute and Clinic, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA
    Mol Psychiatry 12:105-13, 1. 2007
    ..This study provides suggestive evidence for a link between HSV1 exposure and some of the cerebral morphological changes often reported in schizophrenia...
  14. pmc Gender moderates the relationship between mania spectrum and serotonin transporter polymorphisms in depression
    P Rucci
    Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15213, USA
    Am J Med Genet B Neuropsychiatr Genet 150:907-13. 2009
    ..These results should be considered tentative pending replication in other samples...
  15. ncbi request reprint Impact of overlapping recruitment on linkage analysis of complex disorders: simulation studies
    S Davis
    Department of Human Genetics, Graduate School of Pittsburgh, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
    Am J Med Genet 105:141-4. 2001
    ..The implications of this overlapping recruitment on replicative linkage studies are discussed...
  16. doi request reprint Persistent infection with neurotropic herpes viruses and cognitive impairment
    A M M Watson
    Departments of Psychiatry, University of Pittsburgh School of Medicine, Western Psychiatric Institute and Clinic, Pittsburgh, PA, USA
    Psychol Med 43:1023-31. 2013
    ..Composite cognitive measures were derived from nine cognitive domains using principal components of heritability (PCH). Exposure was indexed by antibodies to viral antigens...
  17. doi request reprint Personality and bipolar disorder: dissecting state and trait associations between mood and personality
    J H Barnett
    Psychiatric and Neurodevelopmental Genetics Unit, Center for Human Genetic Research, and Psychiatric Genetics Program in Mood and Anxiety Disorders, Department of Psychiatry, Massachusetts General Hospital, Boston, MA, USA
    Psychol Med 41:1593-604. 2011
    ..This study aimed to determine whether there is a characteristic personality profile in BD, and whether associations between BD and personality are best explained by state or trait effects...
  18. ncbi request reprint Immune related genetic polymorphisms and schizophrenia among the Chinese
    K V Chowdari
    Department of Psychiatry, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
    Hum Immunol 62:714-24. 2001
    ..Persuasive evidence for an association at IL-1 was not detected in either sample. Our results suggest a susceptibility locus for schizophrenia in the HLA region among the Chinese, but further clarification is necessary...
  19. ncbi request reprint Genetic polymorphisms of the RGS4 and dorsolateral prefrontal cortex morphometry among first episode schizophrenia patients
    K M R Prasad
    Department of Psychiatry, Western Psychiatric Institute and Clinic, University of Pittsburgh School of Medicine, 3811 O Hara Street, Pittsburgh, PA 15213, USA
    Mol Psychiatry 10:213-9. 2005
    ..The findings suggest that RGS4 polymorphisms may contribute to structural alterations in the DLPFC...
  20. ncbi request reprint Can clinical features of bipolar-I disorder be assessed reliably on the telephone?
    L K Brar
    Department of Psychiatry, University of Pittsburgh School of Medicine, Western Psychiatric Institute and Clinic, Pittsburgh, PA, USA
    J Affect Disord 71:221-7. 2002
    ..The reliability of telephone interviews for rating 25 selected individual items of the Diagnostic Interview for Genetic Studies (DIGS) was assessed among persons with remitted bipolar disorder I (BPD I, n = 20)...
  21. ncbi request reprint Increased familial risk of the psychotic phenotype of Alzheimer disease
    R A Sweet
    Division of Geriatrics and Neuropsychiatry, School of Medicine, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA, USA
    Neurology 58:907-11. 2002
    ..Psychotic symptoms in patients with AD (AD with psychosis [AD+P]) define a phenotype characterized by more rapid cognitive and functional decline and a liability to aggressive behaviors...