Dennis E Niewoehner

Summary

Affiliation: University of Minnesota
Country: USA

Publications

  1. ncbi request reprint Risk indexes for exacerbations and hospitalizations due to COPD
    Dennis E Niewoehner
    Department of Medicine at Veterans Affairs Medical Centers in Minneapolis, MN 55417, USA
    Chest 131:20-8. 2007
  2. ncbi request reprint The role of systemic corticosteroids in acute exacerbation of chronic obstructive pulmonary disease
    Dennis E Niewoehner
    Pulmonary Section, Veterans Affairs Medical Center, and University of Minnesota, Minneapolis, Minnesota 55417, USA
    Am J Respir Med 1:243-8. 2002
  3. doi request reprint Therapeutic conversion of the combination of ipratropium and albuterol to tiotropium in patients with chronic obstructive pulmonary disease
    Dennis E Niewoehner
    Department of Medicine at Veterans Affairs Medical Centers in Minneapolis, Minneapolis, MN 55417, USA
    Pulm Pharmacol Ther 22:587-92. 2009
  4. ncbi request reprint Prevention of exacerbations of chronic obstructive pulmonary disease with tiotropium, a once-daily inhaled anticholinergic bronchodilator: a randomized trial
    Dennis E Niewoehner
    Minneapolis Veterans Affairs Medical Center, Minneapolis, Minnesota 55417, USA
    Ann Intern Med 143:317-26. 2005
  5. doi request reprint Relation of chronic obstructive pulmonary disease exacerbations to FEV(1)--an intricate tango
    Dennis E Niewoehner
    Pulmonary and Critical Care Section, Veterans Administration Medical Center and University of Minnesota, Minneapolis, MN 55417, USA
    Respiration 77:229-35. 2009
  6. pmc Role of tiotropium in the treatment of COPD
    Kathryn L Rice
    University of Minnesota, Minneapolis, MN, USA
    Int J Chron Obstruct Pulmon Dis 2:95-105. 2007
  7. ncbi request reprint The impact of severe exacerbations on quality of life and the clinical course of chronic obstructive pulmonary disease
    Dennis E Niewoehner
    University of Minnesota, Minneapolis, Minnesota, USA
    Am J Med 119:38-45. 2006
  8. doi request reprint Responses to tiotropium in African-American and Caucasian patients with chronic obstructive pulmonary disease
    Kathryn L Rice
    Veterans Affairs Medical Center, Minneapolis, Minnesota 55417, USA
    Transl Res 152:88-94. 2008
  9. doi request reprint Disease management program for chronic obstructive pulmonary disease: a randomized controlled trial
    Kathryn L Rice
    Pulmonary Section, Department of Medicine, VA Medical Center, Minneapolis, Minnesota 55417, USA
    Am J Respir Crit Care Med 182:890-6. 2010
  10. ncbi request reprint Management of acute exacerbations of chronic obstructive pulmonary disease in the elderly : an appraisal of published evidence
    Ken M Kunisaki
    University of Minnesota, Minneapolis, Minnesota, USA
    Drugs Aging 24:303-24. 2007

Research Grants

  1. Drug therapy for preventing COPD exacerbations
    Dennis Niewoehner; Fiscal Year: 2003

Detail Information

Publications17

  1. ncbi request reprint Risk indexes for exacerbations and hospitalizations due to COPD
    Dennis E Niewoehner
    Department of Medicine at Veterans Affairs Medical Centers in Minneapolis, MN 55417, USA
    Chest 131:20-8. 2007
    ..Our objective was to develop risk indexes for exacerbations and hospitalizations due to exacerbations that might be applied to the individual patient...
  2. ncbi request reprint The role of systemic corticosteroids in acute exacerbation of chronic obstructive pulmonary disease
    Dennis E Niewoehner
    Pulmonary Section, Veterans Affairs Medical Center, and University of Minnesota, Minneapolis, Minnesota 55417, USA
    Am J Respir Med 1:243-8. 2002
    ..Hyperglycemia is the most common adverse event, but secondary infections, mental disturbances, and myopathies may also occur...
  3. doi request reprint Therapeutic conversion of the combination of ipratropium and albuterol to tiotropium in patients with chronic obstructive pulmonary disease
    Dennis E Niewoehner
    Department of Medicine at Veterans Affairs Medical Centers in Minneapolis, Minneapolis, MN 55417, USA
    Pulm Pharmacol Ther 22:587-92. 2009
    ..This trial compared tiotropium, once daily, as a potential alternative to patients already taking the ipratropium/albuterol combination...
  4. ncbi request reprint Prevention of exacerbations of chronic obstructive pulmonary disease with tiotropium, a once-daily inhaled anticholinergic bronchodilator: a randomized trial
    Dennis E Niewoehner
    Minneapolis Veterans Affairs Medical Center, Minneapolis, Minnesota 55417, USA
    Ann Intern Med 143:317-26. 2005
    ..Patients with chronic obstructive pulmonary disease (COPD) frequently develop exacerbations, leading to major clinical and health resource use ramifications...
  5. doi request reprint Relation of chronic obstructive pulmonary disease exacerbations to FEV(1)--an intricate tango
    Dennis E Niewoehner
    Pulmonary and Critical Care Section, Veterans Administration Medical Center and University of Minnesota, Minneapolis, MN 55417, USA
    Respiration 77:229-35. 2009
    ....
  6. pmc Role of tiotropium in the treatment of COPD
    Kathryn L Rice
    University of Minnesota, Minneapolis, MN, USA
    Int J Chron Obstruct Pulmon Dis 2:95-105. 2007
    ..Medico economic analyses suggest that treatment with tiotropium may also be cost-effective, primarily by reducing costs associated with hospitalizations...
  7. ncbi request reprint The impact of severe exacerbations on quality of life and the clinical course of chronic obstructive pulmonary disease
    Dennis E Niewoehner
    University of Minnesota, Minneapolis, Minnesota, USA
    Am J Med 119:38-45. 2006
    ..COPD management should include drugs and other interventions that reduce the frequency of exacerbations and minimize their negative impact on the clinical course of the disease...
  8. doi request reprint Responses to tiotropium in African-American and Caucasian patients with chronic obstructive pulmonary disease
    Kathryn L Rice
    Veterans Affairs Medical Center, Minneapolis, Minnesota 55417, USA
    Transl Res 152:88-94. 2008
    ..African Americans used fewer respiratory medications than Caucasians in this study. We conclude that tiotropium reduces COPD exacerbations and associated health-care use to a similar extent in African Americans compared with Caucasians...
  9. doi request reprint Disease management program for chronic obstructive pulmonary disease: a randomized controlled trial
    Kathryn L Rice
    Pulmonary Section, Department of Medicine, VA Medical Center, Minneapolis, Minnesota 55417, USA
    Am J Respir Crit Care Med 182:890-6. 2010
    ..Objectives: To determine whether a simplified disease management program reduces hospital admissions and emergency department (ED) visits due to COPD...
  10. ncbi request reprint Management of acute exacerbations of chronic obstructive pulmonary disease in the elderly : an appraisal of published evidence
    Ken M Kunisaki
    University of Minnesota, Minneapolis, Minnesota, USA
    Drugs Aging 24:303-24. 2007
    ..Mucolytic agents, pulmonary rehabilitation, and case management programmes may also reduce exacerbation risk, but the current evidence supporting these interventions is weaker...
  11. pmc Vitamin D levels and risk of acute exacerbations of chronic obstructive pulmonary disease: a prospective cohort study
    Ken M Kunisaki
    Pulmonary Section, Minneapolis Veterans Affairs Medical Center, Minnesota 55417, USA
    Am J Respir Crit Care Med 185:286-90. 2012
    ..We hypothesized that low blood levels of 25(OH)D in patients with chronic obstructive pulmonary disease (COPD) would be associated with an increased risk of acute exacerbations of COPD (AECOPD)...
  12. doi request reprint Exhaled nitric oxide, systemic inflammation, and the spirometric response to inhaled fluticasone propionate in severe chronic obstructive pulmonary disease: a prospective study
    Ken M Kunisaki
    Division of Pulmonary, Allergy, Critical Care and Sleep, University of Minnesota, USA
    Ther Adv Respir Dis 2:55-64. 2008
    ..We evaluated the ability of exhaled nitric oxide (FENO) and serum inflammatory markers (C-reactive protein [CRP], interleukin-6 [IL-6], and interleukin-8 [IL-8]) to independently predict spirometric responses to ICS in patients with COPD...
  13. ncbi request reprint Clinical efficacy of OM-85 BV in COPD and chronic bronchitis: a systematic review
    Mark D Sprenkle
    Division of Pulmonary and Critical Care Medicine, Hennepin County Medical Center, Pulmonary Medicine 865B, 701 Park Ave, Minneapolis, Minnesota 55415, USA
    COPD 2:167-75. 2005
    ..Further randomized controlled trials enrolling large numbers of persons with well-defined COPD are necessary to confirm the effectiveness of this agent...
  14. ncbi request reprint Interventions to prevent chronic obstructive pulmonary disease exacerbations
    Dennis E Niewoehner
    Pulmonary Section, Veterans Affairs Medical Center, and Department of Medicine, University of Minnesota, Minneapolis, Minnesota 55417, USA
    Am J Med 117:41S-48S. 2004
    ..This article discusses pharmacologic therapy and other measures for preventing exacerbations and hospitalizations due to exacerbations of COPD...
  15. ncbi request reprint The Veterans Short Form 36 questionnaire is predictive of mortality and health-care utilization in a population of veterans with a self-reported diagnosis of asthma or COPD
    Mark D Sprenkle
    Division of Pulmonary and Critical Care Medicine, Hennepin County Medical Center, Minneapolis, MN 55415, USA
    Chest 126:81-9. 2004
    ..However, as their predictive capacity for mortality or medical utilization is less well defined, we sought to examine the relationship of a general measure of HRQL and outcomes in persons with obstructive lung disease...
  16. ncbi request reprint Inhaled corticosteroids for chronic obstructive pulmonary disease: a status report
    Dennis E Niewoehner
    Am J Respir Crit Care Med 175:103-4. 2007
  17. ncbi request reprint Screening for lung cancer: the guidelines
    Peter B Bach
    Health Outcomes Research Group, Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, Box 221, New York, NY 10021, USA
    Chest 123:83S-88S. 2003
    ..We recommend that individuals should only be screened with LDCT in the context of well-designed clinical trials...

Research Grants1

  1. Drug therapy for preventing COPD exacerbations
    Dennis Niewoehner; Fiscal Year: 2003
    ..Both trials are designed with 80% power to show a 30% reduction in severe exacerbations at a significance level of 0.05. ..