J NickersonSummaryAffiliation: University of Massachusetts Medical School Country: USA Publications
| Collaborators
|
Detail Information
Publications
Increasingly transformed MCF-10A cells have a progressively tumor-like phenotype in three-dimensional basement membrane cultureKaren M Imbalzano
Department of Cell Biology, University of Massachusetts Medical School, Worcester, MA 01655, USA
Cancer Cell Int 9:7. 2009....
Experimental observations of a nuclear matrixJ Nickerson
Department of Cell Biology and Cancer Center, University of Massachusetts Medical School, Worcester, MA 01655, USA
J Cell Sci 114:463-74. 2001..Only by achieving a biochemical characterization of the nuclear matrix will we advance beyond simple microscopic observations of structure to a better understanding of nuclear matrix function, regulation and post-mitotic assembly...- The biochemistry of RNA metabolism studied in situJeffrey A Nickerson
Department of Cell Biology and Cancer Center, University of Massachusetts Medical School, Worcester, Massachusetts 01655, USA
RNA Biol 6:25-30. 2009..A newer technique--in vitro FRAP--assesses the regulation of binding and complex formation by co-factors in the nucleus... - Architectural genetic and epigenetic control of regulatory networks: compartmentalizing machinery for transcription and chromatin remodeling in nuclear microenvironmentsGary S Stein
Department of Cell Biology, University of Massachusetts Medical School and Cancer Center, Worcester, MA 01655, USA
Crit Rev Eukaryot Gene Expr 20:149-55. 2010..Mechanistic understanding of the architectural assembly of regulatory machinery can serve as a basis for treating cancer with high specificity and minimal off-target effects... - An architectural genetic and epigenetic perspectiveGary S Stein
Department of Cell Biology and Cancer Center, University of Massachusetts Medical School, 55 Lake Avenue North, Worcester, MA 01655, USA
Integr Biol (Camb) 3:297-303. 2011.... - In vitro FRAP reveals the ATP-dependent nuclear mobilization of the exon junction complex protein SRm160Stefan Wagner
Dept of Cell Biology, S7 214, University of Massachusetts Medical School, 55 Lake Ave, Worcester, MA 01655, USA
J Cell Biol 164:843-50. 2004..In vitro fluorescence recovery after photobleaching is a powerful tool for identifying cofactors required for nuclear binding and mobility... 
Binding of ATP to UAP56 is necessary for mRNA exportKrishna P Kota
Department of Cell Biology S7 214, University of Massachusetts Medical School, Worcester, MA 01655, USA
J Cell Sci 121:1526-37. 2008..This was confirmed using a point mutant of UAP56 that did not bind ATP. Point mutation of UAP56 to eliminate ATP binding did not affect RNA splicing, but strongly inhibited the export of mRNA to the cytoplasm...- Inducible changes in cell size and attachment area due to expression of a mutant SWI/SNF chromatin remodeling enzymeDavid A Hill
Department of Cell Biology, University of Massachusetts Medical School, 55 Lake Avenue North, Worcester, MA 01655, USA
J Cell Sci 117:5847-54. 2004..These findings demonstrate that gene expression pathways affected by chromatin remodeling enzymes can regulate the physical dimensions of mammalian cell morphology... - Subnuclear localization and intranuclear trafficking of transcription factorsSayyed K Zaidi
Department of Cell Biology, University of Massachusetts Medical School, Worcester, MA, USA
Methods Mol Biol 647:77-93. 2010..Here we provide methodologies to characterize nuclear organization of regulatory machinery by in situ immunofluorescence microscopy... - Brg1, the ATPase subunit of the SWI/SNF chromatin remodeling complex, is required for myeloid differentiation to granulocytesDiana Vradii
Department of Cell Biology and Cancer Center, University of Massachusetts Medical School, Worcester, Massachusetts 01655 0106, USA
J Cell Physiol 206:112-8. 2006..This dependency on Brg1 may reflect a stringent requirement for chromatin remodeling at a critical stage of hematopoietic cell maturation...