J Nickerson

Summary

Affiliation: University of Massachusetts Medical School
Country: USA

Publications

  1. pmc In vitro FRAP reveals the ATP-dependent nuclear mobilization of the exon junction complex protein SRm160
    Stefan Wagner
    Dept of Cell Biology, S7 214, University of Massachusetts Medical School, 55 Lake Ave, Worcester, MA 01655, USA
    J Cell Biol 164:843-50. 2004
  2. pmc Increasingly transformed MCF-10A cells have a progressively tumor-like phenotype in three-dimensional basement membrane culture
    Karen M Imbalzano
    Department of Cell Biology, University of Massachusetts Medical School, Worcester, MA 01655, USA
    Cancer Cell Int 9:7. 2009
  3. ncbi request reprint Experimental observations of a nuclear matrix
    J Nickerson
    Department of Cell Biology and Cancer Center, University of Massachusetts Medical School, Worcester, MA 01655, USA
    J Cell Sci 114:463-74. 2001
  4. ncbi request reprint The biochemistry of RNA metabolism studied in situ
    Jeffrey A Nickerson
    Department of Cell Biology and Cancer Center, University of Massachusetts Medical School, Worcester, Massachusetts 01655, USA
    RNA Biol 6:25-30. 2009
  5. pmc Architectural genetic and epigenetic control of regulatory networks: compartmentalizing machinery for transcription and chromatin remodeling in nuclear microenvironments
    Gary S Stein
    Department of Cell Biology, University of Massachusetts Medical School and Cancer Center, Worcester, MA 01655, USA
    Crit Rev Eukaryot Gene Expr 20:149-55. 2010
  6. pmc An architectural genetic and epigenetic perspective
    Gary S Stein
    Department of Cell Biology and Cancer Center, University of Massachusetts Medical School, 55 Lake Avenue North, Worcester, MA 01655, USA
    Integr Biol (Camb) 3:297-303. 2011
  7. doi request reprint Binding of ATP to UAP56 is necessary for mRNA export
    Krishna P Kota
    Department of Cell Biology S7 214, University of Massachusetts Medical School, Worcester, MA 01655, USA
    J Cell Sci 121:1526-37. 2008
  8. ncbi request reprint Inducible changes in cell size and attachment area due to expression of a mutant SWI/SNF chromatin remodeling enzyme
    David A Hill
    Department of Cell Biology, University of Massachusetts Medical School, 55 Lake Avenue North, Worcester, MA 01655, USA
    J Cell Sci 117:5847-54. 2004
  9. pmc Subnuclear localization and intranuclear trafficking of transcription factors
    Sayyed K Zaidi
    Department of Cell Biology, University of Massachusetts Medical School, Worcester, MA, USA
    Methods Mol Biol 647:77-93. 2010
  10. ncbi request reprint Brg1, the ATPase subunit of the SWI/SNF chromatin remodeling complex, is required for myeloid differentiation to granulocytes
    Diana Vradii
    Department of Cell Biology and Cancer Center, University of Massachusetts Medical School, Worcester, Massachusetts 01655 0106, USA
    J Cell Physiol 206:112-8. 2006

Collaborators

  • Anthony N Imbalzano
  • D A Hill
  • Gary S Stein
  • Sayyed K Zaidi
  • Andre J Van Wijnen
  • Janet L Stein
  • Jane B Lian
  • Krishna P Kota
  • Martin Montecino
  • Stefan Wagner
  • Daniel W Young
  • Karen M Imbalzano
  • Diana Vradii
  • Martin A Montecino
  • Ricardo F Medina
  • Shirwin M Pockwinse
  • Rachit Bakshi
  • Amjad Javed
  • Syed A Ali
  • Iva Tatarkova
  • Elvira Huerta
  • Jean M Underwood
  • Stefan R Wagner
  • Diem N Doan
  • Simion Chiosea
  • Maria Ivshina

Detail Information

Publications10

  1. pmc In vitro FRAP reveals the ATP-dependent nuclear mobilization of the exon junction complex protein SRm160
    Stefan Wagner
    Dept of Cell Biology, S7 214, University of Massachusetts Medical School, 55 Lake Ave, Worcester, MA 01655, USA
    J Cell Biol 164:843-50. 2004
    ..In vitro fluorescence recovery after photobleaching is a powerful tool for identifying cofactors required for nuclear binding and mobility...
  2. pmc Increasingly transformed MCF-10A cells have a progressively tumor-like phenotype in three-dimensional basement membrane culture
    Karen M Imbalzano
    Department of Cell Biology, University of Massachusetts Medical School, Worcester, MA 01655, USA
    Cancer Cell Int 9:7. 2009
    ....
  3. ncbi request reprint Experimental observations of a nuclear matrix
    J Nickerson
    Department of Cell Biology and Cancer Center, University of Massachusetts Medical School, Worcester, MA 01655, USA
    J Cell Sci 114:463-74. 2001
    ..Only by achieving a biochemical characterization of the nuclear matrix will we advance beyond simple microscopic observations of structure to a better understanding of nuclear matrix function, regulation and post-mitotic assembly...
  4. ncbi request reprint The biochemistry of RNA metabolism studied in situ
    Jeffrey A Nickerson
    Department of Cell Biology and Cancer Center, University of Massachusetts Medical School, Worcester, Massachusetts 01655, USA
    RNA Biol 6:25-30. 2009
    ..A newer technique--in vitro FRAP--assesses the regulation of binding and complex formation by co-factors in the nucleus...
  5. pmc Architectural genetic and epigenetic control of regulatory networks: compartmentalizing machinery for transcription and chromatin remodeling in nuclear microenvironments
    Gary S Stein
    Department of Cell Biology, University of Massachusetts Medical School and Cancer Center, Worcester, MA 01655, USA
    Crit Rev Eukaryot Gene Expr 20:149-55. 2010
    ..Mechanistic understanding of the architectural assembly of regulatory machinery can serve as a basis for treating cancer with high specificity and minimal off-target effects...
  6. pmc An architectural genetic and epigenetic perspective
    Gary S Stein
    Department of Cell Biology and Cancer Center, University of Massachusetts Medical School, 55 Lake Avenue North, Worcester, MA 01655, USA
    Integr Biol (Camb) 3:297-303. 2011
    ....
  7. doi request reprint Binding of ATP to UAP56 is necessary for mRNA export
    Krishna P Kota
    Department of Cell Biology S7 214, University of Massachusetts Medical School, Worcester, MA 01655, USA
    J Cell Sci 121:1526-37. 2008
    ..This was confirmed using a point mutant of UAP56 that did not bind ATP. Point mutation of UAP56 to eliminate ATP binding did not affect RNA splicing, but strongly inhibited the export of mRNA to the cytoplasm...
  8. ncbi request reprint Inducible changes in cell size and attachment area due to expression of a mutant SWI/SNF chromatin remodeling enzyme
    David A Hill
    Department of Cell Biology, University of Massachusetts Medical School, 55 Lake Avenue North, Worcester, MA 01655, USA
    J Cell Sci 117:5847-54. 2004
    ..These findings demonstrate that gene expression pathways affected by chromatin remodeling enzymes can regulate the physical dimensions of mammalian cell morphology...
  9. pmc Subnuclear localization and intranuclear trafficking of transcription factors
    Sayyed K Zaidi
    Department of Cell Biology, University of Massachusetts Medical School, Worcester, MA, USA
    Methods Mol Biol 647:77-93. 2010
    ..Here we provide methodologies to characterize nuclear organization of regulatory machinery by in situ immunofluorescence microscopy...
  10. ncbi request reprint Brg1, the ATPase subunit of the SWI/SNF chromatin remodeling complex, is required for myeloid differentiation to granulocytes
    Diana Vradii
    Department of Cell Biology and Cancer Center, University of Massachusetts Medical School, Worcester, Massachusetts 01655 0106, USA
    J Cell Physiol 206:112-8. 2006
    ..This dependency on Brg1 may reflect a stringent requirement for chromatin remodeling at a critical stage of hematopoietic cell maturation...