Peter F Nichol

Summary

Affiliation: University of Wisconsin
Country: USA

Publications

  1. pmc Retinaldehyde dehydrogenase 2 is down-regulated during duodenal atresia formation in Fgfr2IIIb-/- mice
    Peter F Nichol
    Department of Surgery, Section of Pediatric Surgery, University of Wisconsin SMPH, Madison, Wisconsin 53792, USA
    J Surg Res 175:82-7. 2012
  2. doi request reprint Clinical considerations in gastroschisis: incremental advances against a congenital anomaly with severe secondary effects
    Peter F Nichol
    University of Wisconsin and American Family Children s Hospital, Madison, WI 53792, USA
    Am J Med Genet C Semin Med Genet 148:231-40. 2008
  3. pmc Humans, mice, and mechanisms of intestinal atresias: a window into understanding early intestinal development
    Peter F Nichol
    Department of Surgery, University of Wisconsin School of Medicine and Public Health, 600 Highland Avenue H4 785c CSC, Madison, WI 53792, USA
    J Gastrointest Surg 15:694-700. 2011
  4. doi request reprint Conditional mutation of fibroblast growth factor receptors 1 and 2 results in an omphalocele in mice associated with disruptions in ventral body wall muscle formation
    Peter F Nichol
    University of Wisconsin School of Medicine and Public Health Department of Surgery, Madison, WI 53792, USA
    J Pediatr Surg 46:90-6. 2011
  5. pmc Pitx2 is a critical early regulatory gene in normal cecal development
    Peter F Nichol
    Department of Surgery, Section of Pediatric Surgery, University of Wisconsin SMPH, Madison, Wisconsin 53792, USA
    J Surg Res 170:107-11. 2011
  6. pmc A more efficient method to generate null mutants using Hprt-Cre with floxed alleles
    Peter F Nichol
    Section of Pediatric Surgery, Department of Surgery, University of Wisconsin SMPH, Madison, WI 53792, USA
    J Pediatr Surg 46:1711-9. 2011
  7. pmc Haploinsufficiency of retinaldehyde dehydrogenase 2 decreases the severity and incidence of duodenal atresia in the fibroblast growth factor receptor 2IIIb-/- mouse model
    Amy L Reeder
    Department of Surgery, Section of Pediatric Surgery, University of Wisconsin School of Medicine and Public Health, Madison, WI, USA
    Surgery 152:768-75; discussion 775-6. 2012
  8. doi request reprint Muscle patterning in mouse and human abdominal wall development and omphalocele specimens of humans
    Peter F Nichol
    Department of Surgery, Section of Pediatric Surgery, University of Wisconsin SMPH, Madison, Wisconsin, USA
    Anat Rec (Hoboken) 295:2129-40. 2012
  9. pmc Formation of intestinal atresias in the Fgfr2IIIb-/- mice is not associated with defects in notochord development or alterations in Shh expression
    Amy L Reeder
    University of Wisconsin SMPH Department of Surgery, Section of Pediatric Surgery, Madison, Wisconsin 53792, USA
    J Surg Res 177:139-45. 2012
  10. pmc Formation of duodenal atresias in fibroblast growth factor receptor 2IIIb-/- mouse embryos occurs in the absence of an endodermal plug
    Robert A Botham
    Section of Pediatric Surgery, Department of Surgery, University of Wisconsin SMPH Madison, Wis 53792, USA
    J Pediatr Surg 47:1369-79. 2012

Collaborators

Detail Information

Publications14

  1. pmc Retinaldehyde dehydrogenase 2 is down-regulated during duodenal atresia formation in Fgfr2IIIb-/- mice
    Peter F Nichol
    Department of Surgery, Section of Pediatric Surgery, University of Wisconsin SMPH, Madison, Wisconsin 53792, USA
    J Surg Res 175:82-7. 2012
    ....
  2. doi request reprint Clinical considerations in gastroschisis: incremental advances against a congenital anomaly with severe secondary effects
    Peter F Nichol
    University of Wisconsin and American Family Children s Hospital, Madison, WI 53792, USA
    Am J Med Genet C Semin Med Genet 148:231-40. 2008
    ....
  3. pmc Humans, mice, and mechanisms of intestinal atresias: a window into understanding early intestinal development
    Peter F Nichol
    Department of Surgery, University of Wisconsin School of Medicine and Public Health, 600 Highland Avenue H4 785c CSC, Madison, WI 53792, USA
    J Gastrointest Surg 15:694-700. 2011
    ..Recent work in animal models is now calling for a reassessment of these widely held paradigms...
  4. doi request reprint Conditional mutation of fibroblast growth factor receptors 1 and 2 results in an omphalocele in mice associated with disruptions in ventral body wall muscle formation
    Peter F Nichol
    University of Wisconsin School of Medicine and Public Health Department of Surgery, Madison, WI 53792, USA
    J Pediatr Surg 46:90-6. 2011
    ..We observed that fibroblast growth factor receptors 1 and 2 (Fgfr1, Fgfr2) are expressed during abdominal wall development in mice and hypothesized that conditional mutation of these genes would result in abdominal wall defects...
  5. pmc Pitx2 is a critical early regulatory gene in normal cecal development
    Peter F Nichol
    Department of Surgery, Section of Pediatric Surgery, University of Wisconsin SMPH, Madison, Wisconsin 53792, USA
    J Surg Res 170:107-11. 2011
    ..We examined the expression of Pitx2 in the cecum and hypothesized that homozygous null mutation of Pitx2 would result in cecal agenesis...
  6. pmc A more efficient method to generate null mutants using Hprt-Cre with floxed alleles
    Peter F Nichol
    Section of Pediatric Surgery, Department of Surgery, University of Wisconsin SMPH, Madison, WI 53792, USA
    J Pediatr Surg 46:1711-9. 2011
    ....
  7. pmc Haploinsufficiency of retinaldehyde dehydrogenase 2 decreases the severity and incidence of duodenal atresia in the fibroblast growth factor receptor 2IIIb-/- mouse model
    Amy L Reeder
    Department of Surgery, Section of Pediatric Surgery, University of Wisconsin School of Medicine and Public Health, Madison, WI, USA
    Surgery 152:768-75; discussion 775-6. 2012
    ..To test this, we rendered Fgfr2IIIb(-/-) embryos haploinsufficient for the Raldh2 and examined these embryos for the incidence and severity of duodenal atresia...
  8. doi request reprint Muscle patterning in mouse and human abdominal wall development and omphalocele specimens of humans
    Peter F Nichol
    Department of Surgery, Section of Pediatric Surgery, University of Wisconsin SMPH, Madison, Wisconsin, USA
    Anat Rec (Hoboken) 295:2129-40. 2012
    ..These latter findings support a model of normal abdominal wall development in which positional information instructs the orientation of myoblasts as they organize into individual muscle groups...
  9. pmc Formation of intestinal atresias in the Fgfr2IIIb-/- mice is not associated with defects in notochord development or alterations in Shh expression
    Amy L Reeder
    University of Wisconsin SMPH Department of Surgery, Section of Pediatric Surgery, Madison, Wisconsin 53792, USA
    J Surg Res 177:139-45. 2012
    ..These embryos develop colonic atresias (100% penetrance) and duodenal atresias (42% penetrance)...
  10. pmc Formation of duodenal atresias in fibroblast growth factor receptor 2IIIb-/- mouse embryos occurs in the absence of an endodermal plug
    Robert A Botham
    Section of Pediatric Surgery, Department of Surgery, University of Wisconsin SMPH Madison, Wis 53792, USA
    J Pediatr Surg 47:1369-79. 2012
    ..These lines of data led us to hypothesize that mice are able to form a duodenal atresia in the absence of an endodermal plug. To test this hypothesis, we examined duodenal development in wild-type and Fgfr2IIIb-/- embryos...
  11. doi request reprint Utility and limits of Hprt-Cre technology in generating mutant mouse embryos
    Krzysztof M Zaremba
    Division of Pediatric Surgery, Department of Surgery, University of Wisconsin SMPH Madison, Madison, Wisconsin
    J Surg Res 187:386-93. 2014
    ..We set out to confirm the effectiveness of this approach with other alleles and hypothesized that it would increase efficiency in generating compound mutants...
  12. doi request reprint Enlarging unilateral breast mass in an adolescent male: an unusual presentation of intraductal papilloma
    Emily T Durkin
    Department of Surgery, University of Wisconsin School of Medicine and Public Health, Madison, WI, USA
    J Pediatr Surg 46:e33-5. 2011
    ..We report the case of a 14-year-old boy who presented with an enlarging unilateral breast mass, which was found to be owing to an intraductal papilloma at the time of surgical excision...
  13. doi request reprint What is the optimal treatment for children with primary hyperparathyroidism?
    Emily T Durkin
    Department of Surgery, University of Wisconsin School of Medicine and Public Health, Madison, WI 53792 3236, USA
    J Pediatr Surg 45:1142-6. 2010
    ..We hypothesized that primary hyperparathyroidism in children, in the absence of a family history, is caused by single-gland disease and is amenable to minimally invasive parathyroidectomy (MIP)...
  14. doi request reprint Closed gastroschisis: total parenteral nutrition-free survival with aggressive attempts at bowel preservation and intestinal adaptation
    Sarah A Vogler
    Department of Surgery, University of Utah, Salt Lake City, UT 84132, USA
    J Pediatr Surg 43:1006-10. 2008
    ..In infants with gastroschisis antenatal closure of the umbilical defect results in a proximal atresia with ischemia and/or volvulus of the extracorporeal midgut. It has been described as "closed gastroschisis" or "vanishing midgut."..