Kristin L Nichol
Affiliation: University of Minnesota
- Colds and influenza-like illnesses in university students: impact on health, academic and work performance, and health care useKristin L Nichol
Medicine Service, Veterans Affairs Medical Center, Minneapolis, Minnesota 55417, USA
Clin Infect Dis 40:1263-70. 2005..We sought to assess the impact of URIs (colds and influenza-like illnesses [ILIs]) on the health, academic and work performance, and health care use of university students...
- Influenza vaccination among college and university students: impact on influenzalike illness, health care use, and impaired school performanceKristin L Nichol
VA Medical Center, Minneapolis, MN 55417, USA
Arch Pediatr Adolesc Med 162:1113-8. 2008..To assess influenza vaccine effectiveness against influenzalike illness (ILI) and ILI impact on health care use and school performance among college and university students...
- Health-related quality of life predicts future health care utilization and mortality in veterans with self-reported physician-diagnosed arthritis: the veterans arthritis quality of life studyJasvinder A Singh
Rheumatology Section, Medicine Service, VA Medical Center, Minneapolis, MN 55417, USA
Semin Arthritis Rheum 34:755-65. 2005..To investigate whether health-related quality of life (HRQOL) measures predict health care utilization and mortality in a cohort of veterans with self-reported physician-diagnosed arthritis...
- The Veterans Short Form 36 questionnaire is predictive of mortality and health-care utilization in a population of veterans with a self-reported diagnosis of asthma or COPDMark D Sprenkle
Division of Pulmonary and Critical Care Medicine, Hennepin County Medical Center, Minneapolis, MN 55415, USA
Chest 126:81-9. 2004..However, as their predictive capacity for mortality or medical utilization is less well defined, we sought to examine the relationship of a general measure of HRQL and outcomes in persons with obstructive lung disease...
- Heterogeneity of influenza case definitions and implications for interpreting and comparing study resultsKristin L Nichol
University of Minnesota, Medicine Service 111, Minneapolis Veterans Affairs Medical Center, 1 Veterans Drive, Minneapolis, MN 55417, USA
Vaccine 24:6726-8. 2006....
- Rapid diagnosis of influenza infection in older adults: influence on clinical care in a routine clinical settingSarah J D'Heilly
VA Medical Center, Minneapolis, MN, USA
J Clin Virol 42:124-8. 2008..Laboratory diagnosis of influenza has previously relied on viral isolation in culture. Rapid antigen tests (RATs) are now available but few studies have examined their use in older adults under routine clinical conditions...
- Influenza vaccination in the elderly: impact on hospitalisation and mortalityKristin L Nichol
Minneapolis Veterans Affairs Medical Center, University of Minnesota, Minneapolis, Minnesota 55417, USA
Drugs Aging 22:495-515. 2005..Enhancing vaccine delivery to elderly persons would represent important progress toward that goal...
- Improving influenza vaccination rates among adultsKristin L Nichol
University of Minnesota, USA
Cleve Clin J Med 73:1009-15. 2006..We should also consider alternative paradigms for vaccine delivery, and be sure to be vaccinated ourselves...
- Vaccines for seasonal and pandemic influenzaKristin L Nichol
University of Minnesota and Minneapolis VA Medical Center, Minneapolis, MN, USA
J Infect Dis 194:S111-8. 2006..Additional experimental approaches are required to achieve the ultimate goal for seasonal and pandemic influenza prevention--namely, the ability to generate broadly cross-reactive and durable protection in humans...
- Influence of clinical case definitions with differing levels of sensitivity and specificity on estimates of the relative and absolute health benefits of influenza vaccination among healthy working adults and implications for economic analysesKristin L Nichol
Minneapolis VA Medical Center and University of Minnesota, Medicine Service 111, 1 Veterans Drive, Minneapolis, MN 55417, USA
Virus Res 103:3-8. 2004..The definitions of clinical influenza illness and outcome periods should be selected to match the study question...
- Cost effectiveness of influenza vaccination for healthy persons between ages 65 and 74 yearsKristin L Nichol
VA Medical Center, Medicine Service 111, One Veterans Drive, Minneapolis, MN 55417, USA
Vaccine 20:S21-4. 2002..The findings of this study again affirm the value of an age-based strategy for routine influenza vaccination of all elderly persons including healthy elderly persons between 65 and 74 years...
- Effectiveness of influenza vaccine in the community-dwelling elderlyKristin L Nichol
Medicine Service and Center for Chronic Disease Outcomes Research, Minneapolis Veterans Affairs Medical Center and University of Minnesota, Minneapolis 55417, USA
N Engl J Med 357:1373-81. 2007..This study examined the effectiveness of influenza vaccine in seniors over the long term while addressing potential bias and residual confounding in the results...
- Cost benefit of influenza vaccination in healthy, working adults: an economic analysis based on the results of a clinical trial of trivalent live attenuated influenza virus vaccineKristin L Nichol
VA Medical Center, Medicine Service 111, One Veterans Drive, Minneapolis, MN 55417, USA
Vaccine 21:2207-17. 2003..We therefore conducted a cost benefit analysis of influenza vaccination of healthy working adults utilizing clinical outcome data from a trial of LAIV in healthy working adults...
- Influenza vaccination and reduction in hospitalizations for cardiac disease and stroke among the elderlyKristin L Nichol
Veterans Affairs Medical Center and the University of Minnesota, Minneapolis 55417, USA
N Engl J Med 348:1322-32. 2003..During two influenza seasons, we assessed the influence of vaccination against influenza on the risk of hospitalization for heart disease and stroke, hospitalization for pneumonia and influenza, and death from all causes...
- The efficacy, effectiveness and cost-effectiveness of inactivated influenza virus vaccinesKristin L Nichol
VA Medical Center and University of Minnesota, VA Medical Center, 1 Veterans Drive, Minneapolis, MN 55417, USA
Vaccine 21:1769-75. 2003..Additional health economic studies from developing countries and from tropical/subtropical regions will be vitally important for better understanding of the global burden of influenza and potential benefits of vaccination...
- Modeling seasonal influenza outbreak in a closed college campus: impact of pre-season vaccination, in-season vaccination and holidays/breaksKristin L Nichol
Research Service, Veterans Affairs Medical Center, Minneapolis, Minnesota, United States of America
PLoS ONE 5:e9548. 2010..We conducted the present study to assess the impact of various vaccination strategies including delayed (i.e., in-season) vaccination on influenza outbreaks on a college campus...
- Telephone survey assessment of household patterns of influenza vaccination, Twin Cities seven county metro area, 2008-2009Mark A Robien
Division of Epidemiology and Community Health, School of Public Health, University of Minnesota, Minneapolis, MN, USA
Vaccine 29:4033-42. 2011..Continued efforts to monitor and increase household vaccination may be a valuable strategy to protect individuals and communities from influenza...
- Challenges in evaluating influenza vaccine effectiveness and the mortality benefits controversyKristin L Nichol
Research Service 151, VA Medical Center, 1 Veterans Drive, Minneapolis, MN 55417, USA
Vaccine 27:6305-11. 2009..At present, even after taking into account the potential for residual bias and confounding, most studies confirm the benefits of vaccination among the elderly for reducing hospitalization and death...
- Work-site-based influenza vaccination in healthcare and non-healthcare settingsKristin L Nichol
Medicine Service and Center for Chronic Disease Outcomes Research, Veterans Affairs Medical Center, Minnesota 55417, USA
Infect Control Hosp Epidemiol 25:941-5. 2004..Strategies need to be developed to increase vaccination rates so that benefits of vaccination can be realized by employers and employees...
- Health-related quality of life, functional impairment, and healthcare utilization by veterans: veterans' quality of life studyJasvinder A Singh
Medicine Service, Center for Chronic Disease Outcomes Research, Minneapolis Veterans Affairs Medical Center, Minneapolis, Minnesota 55417, USA
J Am Geriatr Soc 53:108-13. 2005..To describe the health status of veterans receiving care in a veterans integrated service network (VISN)...
- Efficacy and effectiveness of influenza vaccinationKristin L Nichol
VA Medical Center, 1 Veterans Drive, Minneapolis, MN 55417, USA
Vaccine 26:D17-22. 2008..Published by Elsevier Ltd...
- Burden of influenza-like illness and effectiveness of influenza vaccination among working adults aged 50-64 yearsKristin L Nichol
Research Service, Minneapolis Veterans Affairs Medical Center, Minneapolis, MN 55417, USA
Clin Infect Dis 48:292-8. 2009..Uncertainties regarding influenza disease impact and benefits of vaccination may contribute to low vaccination rates among adults aged 50-64 years...
- Adherence of mass vaccinators to timing guidelines for influenza vaccinationJackie L Lockman
Medicine Service and Center for Chronic Disease Outcomes Research, Veterans Administration Medical Center, Minneapolis, Minnesota, USA
Am J Prev Med 26:46-50. 2004..Overall, 48.4% of persons vaccinated at any time during the vaccination season were in a high-priority group. CONCLUSIONS: Mass vaccinators can successfully implement influenza vaccination timing guidelines in NTS...
- Safety of influenza vaccinations administered in nontraditional settingsMary Ann Blade
The Medicine Service (111, VA Medical Center, 1 Veterans Drive, Minneapolis, MN 55417, USA
Vaccine 24:4024-7. 2006..No deaths were reported. We conclude that influenza vaccine administration in mass vaccination clinics is safe and adverse events after influenza vaccination in NTS are extremely low...
- Influence of high-risk medical conditions on the effectiveness of influenza vaccination among elderly members of 3 large managed-care organizationsEelko Hak
HealthPartners Research Foundation, Bloomington, IN, USA
Clin Infect Dis 35:370-7. 2002..4- to 4.7-fold higher among high-risk than among healthy elderly persons. All elderly individuals may substantially benefit from vaccination. However, the impact of influenza is greater in persons with high-risk medical conditions...
- Cost-effectiveness of live attenuated influenza vaccine versus inactivated influenza vaccine among children aged 24-59 months in the United StatesBryan R Luce
United BioSource Corporation, 7101 Wisconsin Avenue, Suite 600, Bethesda, MD 20814, USA
Vaccine 26:2841-8. 2008....
- Recognizing influenza in older patients with chronic obstructive pulmonary disease who have received influenza vaccineKathleen M Neuzil
Department of Veterans Affairs Puget Sound Health Care System and University of Washington School of Medicine, Seattle, Washington 98108, USA
Clin Infect Dis 36:169-74. 2003..Additional studies are warranted to define optimal methods for the diagnosis of influenza among older persons with chronic obstructive pulmonary disease...
- Impact of a winter respiratory virus season on patients with COPD and association with influenza vaccinationGeoffrey J Gorse
Division of Infectious Diseases and Immunology, Saint Louis University Health Sciences Center, 3635 Vista Ave FDT 8N, St Louis, MO 63110, USA
Chest 130:1109-16. 2006....
- Immunization for seniorsDale W Bratzler
Oklahoma Foundation for Medical Quality, Inc, Oklahoma City, Oklahoma, USA
J Law Med Ethics 30:128-34. 2002..Despite state efforts to improve vaccination rates of seniors, efforts that have included regulatory and educational approaches, significant challenges remain in designing immunization programs for seniors that are universally effective...
- Efficacy trial of live, cold-adapted and inactivated influenza virus vaccines in older adults with chronic obstructive pulmonary disease: a VA cooperative studyGeoffrey J Gorse
Department of Veterans Affairs, Medical Center, Saint Louis University, St Louis, MO, USA
Vaccine 21:2133-44. 2003..17, 0.53), and -0.05 for type B virus (95% CL: -1.13, 0.48). However, there was a possible advantage for TC over TP in reducing respiratory consequences of an influenza season measured by pulmonary function and symptoms at end of study...
- Development and validation of a clinical prediction rule for hospitalization due to pneumonia or influenza or death during influenza epidemics among community-dwelling elderly personsEelko Hak
Julius Center for General Practice and Patient Oriented Research, University Medical Center, Utrecht, The Netherlands
J Infect Dis 189:450-8. 2004..CONCLUSIONS: This prediction rule may be a useful tool to complement other age-based strategies, to further encourage vaccination, especially among those at the highest risk of serious complications due to influenza...
- Barriers to adult immunizationDavid R Johnson
Scientific and Medical Affairs, Sanofi Pasteur Inc, Swiftwater, Pennsylvania 18017, USA
Am J Med 121:S28-35. 2008..We conclude that a better understanding of why adults do not get vaccinated is important for efforts to increase immunization rates in this broad age group...
- Non-traditional settings for influenza vaccination of adults: costs and cost effectivenessLisa A Prosser
Department of Ambulatory Care and Prevention, Harvard Medical School and Harvard Pilgrim Health Care, Boston, Massachusetts 02215, USA
Pharmacoeconomics 26:163-78. 2008..All analyses are from the US societal perspective...
- Safety and acceptability of pneumococcal vaccinations administered in nontraditional settingsWendy L Bauman
Medicine Service and Center for Chronic Disease Outcomes Research, VA Medical Center and Department of Medicine, University of Minnesota, Minneapolis 55417, USA
Am J Infect Control 30:261-8. 2002..CONCLUSION: Nontraditional settings offer a safe and highly satisfactory option for the administration of pneumococcal vaccinations to the elderly...
- Guidelines for quality standards for immunizationPierce Gardner
Department of Medicine, State University of New York at Stony Brook, Stony Brook, NY 11794, USA
Clin Infect Dis 35:503-11. 2002
- Influenza vaccination: policy versus evidence: no gap between policy and evidenceDavid S Fedson
BMJ 333:1020. 2006
- Safety, efficacy, and effectiveness of live, attenuated, cold-adapted influenza vaccine in an indicated population aged 5-49 yearsRobert B Belshe
Center for Vaccine Development, Saint Louis University School of Medicine, St Louis, MO 63110, USA
Clin Infect Dis 39:920-7. 2004....
- Clinical effectiveness of first and repeat influenza vaccination in adult and elderly diabetic patientsIngrid Looijmans-Van den Akker
Julius Center for Health Sciences and Primary Health Care, University Medical Center, Utrecht, The Netherlands
Diabetes Care 29:1771-6. 2006....
- Benefits of influenza vaccine in US elderly--appreciating issues of confounding bias and precisionEelko Hak
Int J Epidemiol 35:800-2; author reply 799-800. 2006
- Where adults reported receiving influenza vaccination in the United StatesJames A Singleton
National Immunization Program, Centers for Disease Control and Prevention, 1600 Clifton Road, Atlanta, GA 30333, USA
Am J Infect Control 33:563-70. 2005..This study assessed locations at which US adults receive influenza (flu) vaccinations and the relative roles that traditional and nontraditional vaccination settings play in influenza vaccine delivery...
- First do no harm: ensuring that healthcare workers vaccinate and are vaccinatedKristin L Nichol
Infect Control Hosp Epidemiol 24:799-800. 2003