Kathryn E Nichol
Affiliation: University of California
- Three weeks of running wheel exposure improves cognitive performance in the aged Tg2576 mouseKathryn E Nichol
Institute for Brain Aging and Dementia, University of California at Irvine, Irvine, CA 92697 4540, USA
Behav Brain Res 184:124-32. 2007..Our findings demonstrate that exercise can improve cognitive performance in a mouse model of AD even if applied after the development of pathology...
- Exercise alters the immune profile in Tg2576 Alzheimer mice toward a response coincident with improved cognitive performance and decreased amyloidKathryn E Nichol
Institute for Brain Aging and Dementia, University of California, Irvine, Irvine, CA, USA
J Neuroinflammation 5:13. 2008..Our objective was to determine if exercise could induce a shift from the immune profile in aged (17-19 months) Tg2576 mice to a response that reduces Abeta pathology...
- Lack of pathology in a triple transgenic mouse model of Alzheimer's disease after overexpression of the anti-apoptotic protein Bcl-2Troy T Rohn
Department of Biology, Boise State University, Boise, Idaho 83725, USA
J Neurosci 28:3051-9. 2008..These findings suggest that the activation of apoptotic pathways may be an early event in AD and contributes to the pathological processes that promote the disease mechanisms underlying AD...
- Regulation of nitric oxide-dependent vasodilation in coronary arteries of estrogen receptor-alpha-deficient miceJudy M Muller-Delp
Department of Health and Kinesiology, Texas A and M University, College Station, TX 77843, USA
Am J Physiol Heart Circ Physiol 285:H2150-7. 2003..NO-dependent responses are preserved in ERalphaKO mice, possibly through increased SOD-1 expression and enhanced bioavailability of NO...