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Species | Anne NewmanSummaryAffiliation: University of Pittsburgh Country: USA Publications
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Publications
The 10 keys to healthy aging: findings from an innovative prevention program in the communityAnne B Newman
University of Pittsburgh, Pennsylvania
J Aging Health 22:547-66. 2010..To develop and evaluate a novel, comprehensive prevention program for older adults designed to assess and improve adherence to preventive health care goals...
Sarcopenia: alternative definitions and associations with lower extremity functionAnne B Newman
Division of Geriatric Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania 15213, USA
J Am Geriatr Soc 51:1602-9. 2003....
A physiologic index of comorbidity: relationship to mortality and disabilityAnne B Newman
Center for Aging and Population Health, University of Pittsburgh, Graduate School of Public Health, 130 N Bellefield Ave Room 532, Pittsburgh, PA 15213, USA
J Gerontol A Biol Sci Med Sci 63:603-9. 2008..We developed a simple physiologic index of comorbidity by scoring five noninvasive tests across the full range of values. We examined the predictive validity of this index for mortality and disability...- Health and function of participants in the Long Life Family Study: A comparison with other cohortsAnne B Newman
University of Pittsburgh, Graduate School of Public Health, Department of Epidemiology, Center for Aging and Population Health, PA 15213, USA
Aging (Albany NY) 3:63-76. 2011..These findings suggest several priority phenotypes for inclusion in future genetic analysis to identify loci contributing to exceptional survival... - Association of long-distance corridor walk performance with mortality, cardiovascular disease, mobility limitation, and disabilityAnne B Newman
Department of Epidemiology, Physical Therapy, University of Pittsburgh, Pittsburgh, PA 15213, USA
JAMA 295:2018-26. 2006..Extended walking tests have been examined as outcome predictors in medically ill populations but not in community-dwelling older adults... - Strength, but not muscle mass, is associated with mortality in the health, aging and body composition study cohortAnne B Newman
University of Pittsburgh, Department of Epidemiology, 130 N Bellefield Avenue, Room 532, Pittsburgh, PA 15213, USA
J Gerontol A Biol Sci Med Sci 61:72-7. 2006..Although muscle strength and mass are highly correlated, the relationship between direct measures of low muscle mass (sarcopenia) and strength in association with mortality has not been examined... - Progression and regression of sleep-disordered breathing with changes in weight: the Sleep Heart Health StudyAnne B Newman
Department of Epidemiology and Medicine, University of Pittsburgh, Pittsburgh, PA 15213, USA
Arch Intern Med 165:2408-13. 2005..This study aims to determine the relationship between change in weight and progression or remission of SDB by polysomnography... - Total and cause-specific mortality in the cardiovascular health studyAnne B Newman
Departments of Epidemiology and Medicine, University of Pittsburgh, 130 North Bellefield Avenue Room 532, Pittsburgh, PA 15213, USA
J Gerontol A Biol Sci Med Sci 64:1251-61. 2009..Shared risk factors could be targeted for prevention of premature death and the study of longevity... - Long-term function in an older cohort--the cardiovascular health study all stars studyAnne B Newman
Department ofEpidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania 15213, USA
J Am Geriatr Soc 57:432-40. 2009..To evaluate shared and unique risk factors for maintaining physical and cognitive function into the ninth decade and beyond... - Weight change and the conservation of lean mass in old age: the Health, Aging and Body Composition StudyAnne B Newman
Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA 15213, USA
Am J Clin Nutr 82:872-8; quiz 915-6. 2005..Weight loss may contribute to the loss of lean mass with age... - A meta-analysis of four genome-wide association studies of survival to age 90 years or older: the Cohorts for Heart and Aging Research in Genomic Epidemiology ConsortiumAnne B Newman
Department of Epidemiology, Graduate School of Public Health, 130 North Bellefield Avenue, Suite 500, University of Pittsburgh, Pittsburgh, PA 15213, USA
J Gerontol A Biol Sci Med Sci 65:478-87. 2010..Genome-wide association studies (GWAS) may yield insights into longevity... - An overview of the design, implementation, and analyses of longitudinal studies on agingAnne B Newman
Center for Aging and Population Health, Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania 15213, USA
J Am Geriatr Soc 58:S287-91. 2010..Analysis of longitudinal data requires approaches that account for inevitable missing data. New studies should take advantage of the experience obtained from longitudinal studies on aging already conducted... - Walking performance and cardiovascular response: associations with age and morbidity--the Health, Aging and Body Composition StudyAnne B Newman
Division of Geriatric Medicine, Department of Medicine, University of Pittsburgh, Pennsylvania 15213, USA
J Gerontol A Biol Sci Med Sci 58:715-20. 2003..The long-distance corridor walk is a timed 400-meter walk test used to assess walking endurance in well-functioning men and women aged 70-79 in the Health, Aging and Body Composition Study... - Coronary artery calcium, carotid artery wall thickness, and cardiovascular disease outcomes in adults 70 to 99 years oldAnne B Newman
Department of Epidemiology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
Am J Cardiol 101:186-92. 2008..The CCA-IMT was more strongly related to stroke than CAC, but CAC was also a predictor of stroke... - Self-reported napping and duration and quality of sleep in the lifestyle interventions and independence for elders pilot studyJennifer L Picarsic
Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania 15213, USA
J Am Geriatr Soc 56:1674-80. 2008..To determine the prevalence of self-reported napping and its association with subjective nighttime sleep duration and quality, as measured according to sleep-onset latency and sleep efficiency... - Trajectories of dehydroepiandrosterone sulfate predict mortality in older adults: the cardiovascular health studyAnne R Cappola
SCM, Division of Endocrinology, Diabetes, and Metabolism, Department of Medicine, University of Pennsylvania School of Medicine, 764 CRB, 415 Curie Boulevard, Philadelphia, PA 19104, USA
J Gerontol A Biol Sci Med Sci 64:1268-74. 2009..Assessment of an individual's ability to maintain a DHEAS set point, through examination of multiple DHEAS levels over time, may provide insight into biologic aging... - Kidney function as a predictor of noncardiovascular mortalityLinda F Fried
VA Pittsburgh Healthcare System and Renal Electrolyte Division, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15240, USA
J Am Soc Nephrol 16:3728-35. 2005..Kidney function predicts noncardiovascular mortality from multiple causes in the elderly. Further research is needed to understand the mechanisms and evaluate interventions to reduce the high mortality rate in chronic kidney disease... - Change in circulating adiponectin in advanced old age: determinants and impact on physical function and mortality. The Cardiovascular Health Study All Stars StudyJorge R Kizer
Department of Medicine, Weill Cornell Medical College, New York, USA
J Gerontol A Biol Sci Med Sci 65:1208-14. 2010.... - Neck and shoulder pain in 70- to 79-year-old men and women: findings from the Health, Aging and Body Composition StudyMolly T Vogt
Department of Orthopaedic Surgery, University of Pittsburgh, Pittsburgh, PA 15213, USA
Spine J 3:435-41. 2003..Musculoskeletal pain in the cervicobrachial region is considered a major health problem among adults of working age, but little is known about the impact of this pain in the elderly... - How does low back pain impact physical function in independent, well-functioning older adults? Evidence from the Health ABC Cohort and implications for the futureDebra K Weiner
Division of Geriatric Medicine, Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15206, USA
Pain Med 4:311-20. 2003..To determine the relationships between low back pain (LBP) frequency and intensity and self-reported and performance-based physical function in a large cohort of well-functioning older adults... - Poor sleep is associated with poorer physical performance and greater functional limitations in older womenSuzanne E Goldman
Department of Epidemiology, University ofPittsburgh, Pittsburgh, PA, USA
Sleep 30:1317-24. 2007..This study examined the association between disturbed sleep and poorer daytime function in older women... - Sleep-disordered breathing and frailty in the Cardiovascular Health Study CohortYohannes W Endeshaw
Division of Geriatrics and Gerontology, Department of Medicine, Emory University School of Medicine, Atlanta, Georgia 30329, USA
Am J Epidemiol 170:193-202. 2009..The finding of an independent association between SDB and frailty indicator variables among older women could have important implications in interventions aimed at preventing or delaying the progression of frailty... - Weight change, weight change intention, and the incidence of mobility limitation in well-functioning community-dwelling older adultsJung Sun Lee
Healthy Aging Research Program, Department of Epidemiology, University of Pittsburgh, PA 15213, USA
J Gerontol A Biol Sci Med Sci 60:1007-12. 2005..The aim of this study was to determine whether weight, weight change, and weight change intention are associated with risk for mobility limitation in elderly persons... - Central nervous system medication use and incident mobility limitation in community elders: the Health, Aging, and Body Composition studyRobert M Boudreau
Department of Epidemiology, University of Pittsburgh, PA 15213, USA
Pharmacoepidemiol Drug Saf 18:916-22. 2009..To evaluate whether CNS medication use in older adults was associated with a higher risk of future incident mobility limitation... - A prospective study of anemia status, hemoglobin concentration, and mortality in an elderly cohort: the Cardiovascular Health StudyNeil A Zakai
Department of Medicine, University of Vermont College of Medicine and Fletcher Allen Health Care, Burlington, USA
Arch Intern Med 165:2214-20. 2005..Additional study is needed on the clinically valid definition for and causes of anemia in the elderly and on the increased mortality at the extremes of hemoglobin concentrations... - Validation of the health ABC heart failure model for incident heart failure risk prediction: the Cardiovascular Health StudyAndreas Kalogeropoulos
Department of Medicine, Division of Cardiology, Emory University, Atlanta, GA 30322, USA
Circ Heart Fail 3:495-502. 2010..The recently developed and internally validated Health ABC HF model uses 9 routinely available clinical variables to determine incident heart failure risk. In this study, we sought to externally validate the Health ABC HF model... - Sleep-disordered breathing in the National Football LeagueThomas B Rice
Department of Medicine, University of Pittsburgh, Pittsburgh, PA, USA
Sleep 33:819-24. 2010..NFL players have a higher prevalence of hypertension, and we sought to determine the prevalence of SDB among players the NFL and the associations of SDB with anthropometric measures and cardiovascular risk factors... - Factors associated with incidence and persistence of symptoms of disturbed sleep in an elderly cohort: the Cardiovascular Health StudyStuart F Quan
Department of Medicine, Sleep and Arizona Respiratory Centers, University of Arizona College of Medicine, Tucson, Arizona 85724, USA
Am J Med Sci 329:163-72. 2005..Factors influencing these rates were assessed as well... - Elevated aortic pulse wave velocity, a marker of arterial stiffness, predicts cardiovascular events in well-functioning older adultsKim Sutton-Tyrrell
Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, PA 15261, USA
Circulation 111:3384-90. 2005..The objective of this investigation was to determine whether aPWV is associated with total and cardiovascular (CV) mortality and CV events in a community-dwelling sample of older adults... - Diabetes, inflammation, and functional decline in older adults: findings from the Health, Aging and Body Composition (ABC) studyM Kathleen Figaro
Department of Medicine, Vanderbilt University Medical Center GRECC, 1310 24th Ave South, Room 4B111, Nashville, TN 37212, USA
Diabetes Care 29:2039-45. 2006..We examined the effect of C-reactive protein (CRP) and interleukin-6 (IL-6) on the incident mobility limitation in older adults with and without diabetes... - Changes in cognitive function in a randomized trial of physical activity: results of the lifestyle interventions and independence for elders pilot studyJeff D Williamson
Roena Kulynych Center for Memory and Cognition Research, Department of Medicine, Wake Forest University Health Sciences, Winston Salem, North Carolina 27151, USA
J Gerontol A Biol Sci Med Sci 64:688-94. 2009.... - Kidney function predicts the rate of bone loss in older individuals: the Cardiovascular Health StudyLinda F Fried
VA Pittsburgh Healthcare System, Pittsburgh, PA 15240, USA
J Gerontol A Biol Sci Med Sci 61:743-8. 2006.... - The clock drawing test is an independent predictor of incident use of 24-hour care in a retirement communityLaurie L Lavery
Division of Geriatric Medicine, University of Pittsburgh, 3471 Fifth Ave, Suite 500, Pittsburgh, PA 15213, USA
J Gerontol A Biol Sci Med Sci 60:928-32. 2005..We examined the relationship between executive function, measured with a clock drawing protocol (CLOX1) designed to capture executive impairment, and incident need for increased level of care and total mortality... - Nontraumatic fracture risk with diabetes mellitus and impaired fasting glucose in older white and black adults: the health, aging, and body composition studyElsa S Strotmeyer
Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA 15213, USA
Arch Intern Med 165:1612-7. 2005..Fracture prevention needs to target specific risk factors found in older adults with DM... - Limited literacy in older people and disparities in health and healthcare accessRebecca L Sudore
Department of Medicine, Division of Geriatrics, University of California San Francisco, San Francisco, CA, USA
J Am Geriatr Soc 54:770-6. 2006..To determine the relationship between health literacy, demographics, and access to health care... - Common promoter polymorphisms of inflammation and thrombosis genes and longevity in older adults: the cardiovascular health studyAlexander P Reiner
Department of Epidemiology, University of Washington, Seattle, WA 98101, USA
Atherosclerosis 181:175-83. 2005..These findings suggest that modulators of fibrinolytic activity may have a generalized influence on aging, and merit further investigation in studies of genetic determinants of human longevity... - Total and regional adiposity and cognitive change in older adults: The Health, Aging and Body Composition (ABC) studyAlka M Kanaya
Department of Medicine, University of California San Francisco, 94115, USA
Arch Neurol 66:329-35. 2009.... - Short-term weight changes in community-dwelling older adults: the Health, Aging, and Body Composition Weight Change SubstudyJung Sun Lee
University of Pittsburgh, Pittsburgh, PA 15213, USA
Am J Clin Nutr 82:644-50. 2005..The frequency and short-term natural history of weight loss in community-dwelling older adults have not been described. Unintentional weight loss may be more likely to continue than intentional weight loss... - Skeletal muscle fatigue, strength, and quality in the elderly: the Health ABC StudyAndreas Katsiaras
Division of Endocrinology and Metabolism, Department of Medicine, University of Pittsburgh, Pennsylvania, USA
J Appl Physiol 99:210-6. 2005..In conclusion, older men were more fatigue resistant than women, although in both men and women greater fatigue was not related to muscle weakness... - Renin angiotensin system gene polymorphisms modify angiotensin-converting enzyme inhibitors' effect on cognitive function: the health, aging and body composition studyIhab Hajjar
Division of Gerontology, Department of Medicine, Beth Israel Deaconess Medical Center, Boston, Massachusetts 02131, USA
J Am Geriatr Soc 58:1035-42. 2010.... - Serum insulin-like growth factor-1 binding proteins 1 and 2 and mortality in older adults: the Health, Aging, and Body Composition StudyDonglei Hu
Department of Medicine, University of California at San Francisco, San Francisco, California, USA
J Am Geriatr Soc 57:1213-8. 2009..To evaluate the relationship between serum insulin-like growth factor 1 (IGF-1), IGF-1 binding protein 1 (IGFBP-1), and IGF-1 binding protein 2 (IGFBP-2) and fasting insulin, fasting glucose, adiposity, and mortality in older adults... - Risk factors for dementia in the cardiovascular health cognition studyLewis H Kuller
Department of Epidemiology, University of Pittsburgh Graduate School of Public Health, PA 15261, USA
Neuroepidemiology 22:13-22. 2003..The Cardiovascular Health Cognition Study has evaluated the determinants of dementia among 3,608 participants that had a magnetic resonance imaging (MRI) of the brain in 1991 and were followed to 1998-1999... - CRP gene variation and risk of community-acquired pneumoniaKenneth J Mukamal
Department of Medicine, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA
Respirology 15:160-4. 2010..Whether this variation influences risk of infection, and hence whether CRP has anti-infective activity in humans, is uncertain... - Mortality and cardiovascular risk across the ankle-arm index spectrum: results from the Cardiovascular Health StudyANN M O'HARE
Nephrology Division, Department of Medicine, VA Medical Center San Francisco, University of California, San Francisco, CA, USA
Circulation 113:388-93. 2006..A high AAI also appears to be associated with higher mortality risk in select populations. However, mortality and cardiovascular risk across the AAI spectrum have not been described in a more broadly defined population... - Change in cardiovascular risk factors with progression of kidney diseaseLinda F Fried
Renal Section, VA Pittsburgh Healthcare System, Pittsburgh, PA 15240, USA
Am J Nephrol 29:334-41. 2009..We evaluated the change in lipids, inflammatory and procoagulant biomarkers with decline in kidney function in a nested case-cohort study in the Cardiovascular Health Study, a community-based study of adults aged >65 years... - Diabetes is associated independently of body composition with BMD and bone volume in older white and black men and women: The Health, Aging, and Body Composition StudyElsa S Strotmeyer
Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania 15213, USA
J Bone Miner Res 19:1084-91. 2004..01) and higher hip BMD for each race-gender group (p < or = 0.01). Type 2 diabetes was associated with a 4-5% higher total hip BMD in all race-gender groups of elderly adults, independent of body composition and fasting insulin levels... - Fetuin-A and incident diabetes mellitus in older personsJoachim H Ix
Division of Nephrology and Hypertension, Department of Medicine, University of California, San Diego, and San Diego Veterans Affairs Healthcare System, 3350 La Jolla Village Dr, Mail Code 111 H, San Diego, CA 92161, USA
JAMA 300:182-8. 2008..In prior cross-sectional studies in humans, higher fetuin-A levels were associated with insulin resistance. However, the longitudinal association of fetuin-A with incident type 2 diabetes mellitus is unknown... - Chronic kidney disease and functional limitation in older people: health, aging and body composition studyLinda F Fried
Department of Veterans Affairs Pittsburgh Healthcare System, University Drive, Pittsburgh, PA 15240, USA
J Am Geriatr Soc 54:750-6. 2006..To assess whether chronic kidney disease (CKD) is independently associated with incident physical-function limitation... - The relationship between chronically disrupted sleep and healthcare useVishesh K Kapur
Department of Medicine, University of Washington, Seattle 98104, USA
Sleep 25:289-96. 2002..To determine whether chronic sleep deprivation, sleep disruption, sleepiness, insomnia, and OSA are associated with increased healthcare use in a community-based population... - Event-related functional magnetic resonance imaging investigation of executive control in very old individuals with mild cognitive impairmentCaterina Rosano
School of Public Health, Department of Epidemiology, University of Pittsburgh, Pittsburgh, Pennsylvania 15213, USA
Biol Psychiatry 57:761-7. 2005..76, p = .02) but not with changes in accuracy rates. CONCLUSIONS: PPC and dlPFC may show early functional changes associated with MCI... - 4G/5G plasminogen activator inhibitor-1 polymorphisms and haplotypes are associated with pneumoniaSachin Yende
CRISMA Laboratory Clinical Research, Investigation, and Systems Modeling of Acute Illness, Department of Critical Care Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
Am J Respir Crit Care Med 176:1129-37. 2007..Whether variation within the PAI-1 gene is associated with increased susceptibility to infection is unknown... - Obstructive sleep apnea among obese patients with type 2 diabetesGary D Foster
Temple University, Philadelphia, Pennsylvania, USA
Diabetes Care 32:1017-9. 2009..To assess the risk factors for the presence and severity of obstructive sleep apnea (OSA) among obese patients with type 2 diabetes... - Caregiving, mortality, and mobility decline: the Health, Aging, and Body Composition (Health ABC) StudyLisa Fredman
Department of Epidemiology, Boston University School of Public Health, Boston, MA 02118, USA
Arch Intern Med 168:2154-62. 2008..We hypothesized that caregivers may be more physically active than noncaregivers, which may protect them from health decline... - Cystatin C and incident peripheral arterial disease events in the elderly: results from the Cardiovascular Health StudyANN M O'HARE
Nephrology Division, Department of Medicine, and General Internal Medicine Section, Veterans Affairs Medical Center San Francisco, 4150 Clement Street, San Faancisco, CA 94121, USA
Arch Intern Med 165:2666-70. 2005..The association of cystatin C, a novel marker of renal function, with risk for developing complications related to peripheral arterial disease (PAD) has not been examined... - The burden of cardiovascular disease in the elderly: morbidity, mortality, and costsAli Yazdanyar
Center for Aging and Population Health, Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, 130 North Bellefield Avenue, Pittsburgh, PA 15213, USA
Clin Geriatr Med 25:563-77, vii. 2009..This article provides an overview of the epidemiology of CVD in older adults, including an assessment of the impact of CVD on mortality, morbidity, and health care costs... - Parity and cardiovascular disease risk among older women: how do pregnancy complications mediate the association?Janet M Catov
University of Pittsburgh, Department of Obstetrics, Gynecology and Reproductive Sciences, Pittsburgh PA 15213, USA
Ann Epidemiol 18:873-9. 2008..To determine whether parity is associated with increased risk of cardiovascular disease (CVD) after accounting for perinatal complications... - Extent of cardiovascular risk reduction associated with treatment of isolated systolic hypertensionKim Sutton-Tyrrell
Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA 15261, USA
Arch Intern Med 163:2728-31. 2003..However, nearly 20% of older adults remain at high risk of heart disease and stroke from untreated ISH... - Inflammatory and prothrombotic markers and the progression of renal disease in elderly individualsLinda Fried
Renal Section, VA Pittsburgh Healthcare System, University Drive C, Mailstop 111F U, Pittsburgh, PA 15240, USA
J Am Soc Nephrol 15:3184-91. 2004..Inflammatory and prothrombotic markers are predictors for a change in kidney function in elderly individuals. Interventions that reduce inflammation might confer significant cardiovascular and renal benefits... - Focal atrophy and cerebrovascular disease increase dementia risk among cognitively normal older adultsCaterina Rosano
School of Public Health, Department of Epidemiology, University of Pittsburgh, Pennysylvania, USA
J Neuroimaging 17:148-55. 2007.... - Leukocyte Telomere Length Is Not Associated With BMD, Osteoporosis, or Fracture in Older Adults: Results From the Health, Aging and Body Composition StudyJason L Sanders
Medical Scientist Training Program, School of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
J Bone Miner Res 24:1531-6. 2009..TL is not associated with BMD, osteoporosis, or fracture in older men or women in this sample... - Physical activity and functional status in community-dwelling older women: a 14-year prospective studyJennifer S Brach
Department of Physical Therapy, School of Health and Rehabilitation Sciences, University of Pittsburgh, 6035 Forbes Tower, Pittsburgh, PA 15260, USA
Arch Intern Med 163:2565-71. 2003..Short-term prospective studies have shown physical activity to be related to functional status. To our knowledge, the association between physical activity levels and functional status over a longer period has not been established... - Special article: gait measures indicate underlying focal gray matter atrophy in the brain of older adultsCaterina Rosano
Department of Epidemiology, University of Pittsburgh, Pittsburgh, PA, USA
J Gerontol A Biol Sci Med Sci 63:1380-8. 2008..Our objective was to identify the spatial distribution of focal atrophy within mobility-related brain regions in relationship with quantitative gait characteristics... - Cardiovascular disease is associated with greater incident dehydroepiandrosterone sulfate decline in the oldest old: the cardiovascular health study all stars studyJason L Sanders
Department of Medicine, School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA
J Am Geriatr Soc 58:421-6. 2010..To describe cross-sectional and longitudinal associations with dehydroepiandrosterone sulfate (DHEAS) and change in DHEAS with age... - Diabetes mellitus and gait dysfunction: possible explanatory factorsJennifer S Brach
Department of Physical Therapy, School of Health and Rehabilitation Sciences, University of Pittsburgh, 6035 Forbes Tower, Pittsburgh, PA 15260, USA
Phys Ther 88:1365-74. 2008..Limited information regarding potential explanatory factors for this association exists. This study examined the association between diabetes and gait characteristics in older adults and explored potential explanatory factors... - Inflammatory markers and incident fracture risk in older men and women: the Health Aging and Body Composition StudyJane A Cauley
Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania 15261, USA
J Bone Miner Res 22:1088-95. 2007..We tested this hypothesis in relationship to fractures in 2985 men and women enrolled in the Health ABC study. Results showed that subjects with the greatest number of inflammatory markers have the highest risk of fracture... - Multitasking: association between poorer performance and a history of recurrent fallsKimberly A Faulkner
Department of Epidemiology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
J Am Geriatr Soc 55:570-6. 2007..To examine the association between poorer performance on concurrent walking and reaction time and recurrent falls... - Geographic variations in stroke incidence and mortality among older populations in four US communitiesAiman El-Saed
Department of Epidemiology, University of Pittsburgh, 130 N Bellefield Ave, Rm 405, Pittsburgh, PA 15213, USA
Stroke 37:1975-9. 2006..The purpose of this study was to compare stroke incidence and mortality rates in 4 US communities... - Strength and muscle quality in a well-functioning cohort of older adults: the Health, Aging and Body Composition StudyAnne B Newman
Department of Medicine, Division of Geriatric Medicine, University of Pittsburgh School of Medicine, 3520 5th Avenue, Suite 300, Pittsburgh, PA 15213, USA
J Am Geriatr Soc 51:323-30. 2003..To determine whether lower lean mass and higher fat mass have independent effects on the loss of strength and muscle quality in older adults and might explain part of the effect of age... - Influence of marital status on physical activity levels among older adultsKelley K Pettee
University of Pittsburgh, Pittsburgh, PA, USA
Med Sci Sports Exerc 38:541-6. 2006.... - Subclinical atherosclerosis in multiple vascular beds: an index of atherosclerotic burden evaluated in postmenopausal womenKim Sutton-Tyrrell
Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, 130 DeSoto Street, Pittsburgh, PA 15261, USA
Atherosclerosis 160:407-16. 2002..Women with lower premenopausal risk factors did not develop high levels of subclinical atherosclerosis, suggesting that atherosclerosis is a preventable disease in women... - Hearing sensitivity and the risk of incident falls and fracture in older women: the study of osteoporotic fracturesElizabeth L Purchase-Helzner
Department of Epidemiology, University of Pittsburgh, Pittsburgh, PA 15261, USA
Ann Epidemiol 14:311-8. 2004..We further hypothesized that decreased bone mineral density would be associated with hearing loss... - Black and white differences in cognitive function test scores: what explains the difference?Kala M Mehta
Division of Geriatrics, University of California at San Francisco, 94121, USA
J Am Geriatr Soc 52:2120-7. 2004..This study evaluates whether differences in health and socioeconomic indicators, including literacy level, can explain differences in cognitive function test scores between older black and white adults... - Predicting the development of diabetes in older adults: the derivation and validation of a prediction ruleAlka M Kanaya
Department of Medicine and Epidemiology and Biostatics, University of California, San Francisco, California 94115, USA
Diabetes Care 28:404-8. 2005..We created a prediction rule in one sample and prospectively validated it for incident diabetes in a separate cohort... - Is there a biomedical explanation for socioeconomic differences in incident mobility limitation?Annemarie Koster
Department of Health Care Studies, Section Medical Sociology, Universiteit Maastricht, Maastricht, The Netherlands
J Gerontol A Biol Sci Med Sci 60:1022-7. 2005..This study examines the association between socioeconomic status and incident mobility limitation in well-functioning older adults, and seeks to determine whether this link could be explained by biomedical factors... - Muscle mass, muscle strength, and muscle fat infiltration as predictors of incident mobility limitations in well-functioning older personsMarjolein Visser
Institute for Research in Extramural Medicine, VU University Medical Center, Van der Boechorststraat 7, 1081 BT Amsterdam, The Netherlands
J Gerontol A Biol Sci Med Sci 60:324-33. 2005..This study aims to investigate whether low muscle mass, low muscle strength, and greater fat infiltration into the muscle predict incident mobility limitation... - Prognostic value of usual gait speed in well-functioning older people--results from the Health, Aging and Body Composition StudyMatteo Cesari
Department of Aging and Geriatric Research, College of Medicine, Institute on Aging, University of Florida, Gainesville, Florida 32608, USA
J Am Geriatr Soc 53:1675-80. 2005..To define clinically relevant cutpoints for usual gait speed and to investigate their predictive value for health-related events in older persons... - Cross-sectional associations between trunk muscle composition, back pain, and physical function in the health, aging and body composition studyGregory E Hicks
Clinical Research Branch, National Institute on Aging, Baltimore, MD 21201, USA
J Gerontol A Biol Sci Med Sci 60:882-7. 2005..We hypothesized that lower trunk muscle area and attenuation (higher fat infiltration) are associated with decreased functional capacity... - Association of visceral adipose tissue with incident myocardial infarction in older men and women: the Health, Aging and Body Composition StudyBarbara J Nicklas
Section on Gerontology and Geriatric Medicine, Sticht Center on Aging, Wake Forest University School of Medicine, Winston Salem, NC, USA
Am J Epidemiol 160:741-9. 2004..79, 95% confidence interval: 1.24, 2.58 per standard-deviation increase; p < 0.01). The amount of adipose tissue stored in the intraabdominal cavity is an important, independent risk factor for MI in well-functioning, elderly women... - The association between lipid levels and the risks of incident myocardial infarction, stroke, and total mortality: The Cardiovascular Health StudyBruce M Psaty
Cardiovascular Health Research Unit, Departments of Medicine, Epidemiology and Health Services, University of Washington, Seattle, Washington 98101, USA
J Am Geriatr Soc 52:1639-47. 2004..To assess the association between lipid levels and cardiovascular events in older adults... - Relationship of interleukin-6 and tumor necrosis factor-alpha with muscle mass and muscle strength in elderly men and women: the Health ABC StudyMarjolein Visser
Institute for Research in Extramural Medicine, VU University Medical Center, Amsterdam, The Netherlands
J Gerontol A Biol Sci Med Sci 57:M326-32. 2002.... - Leg muscle mass and composition in relation to lower extremity performance in men and women aged 70 to 79: the health, aging and body composition studyMarjolein Visser
Institute for Research in Extramural Medicine, Faculty of Medicine, Vrije Universiteit, Amsterdam, The Netherlands
J Am Geriatr Soc 50:897-904. 2002..Our aim was to determine whether low leg muscle mass and greater fat infiltration in the muscle were associated with poor lower extremity performance (LEP)... - The 6-min walk test: a quick measure of functional status in elderly adultsPaul L Enright
University of Arizona, USA
Chest 123:387-98. 2003..To determine the correlates of the total 6-min walk distance (6MWD) in a population sample of adults > or = 68 years old... - One- and two-year change in body composition as measured by DXA in a population-based cohort of older men and womenMarjolein Visser
Institute for Research in Extramural Medicine, Vrije University Medical Center, 1081 BT Amsterdam, The Netherlands
J Appl Physiol 94:2368-74. 2003..Loss of ALST was greater in men compared with women, and greater in blacks compared with whites, suggesting that men and blacks may be more prone to muscle loss... - Association of high coronary heart disease risk status with circulating oxidized LDL in the well-functioning elderly: findings from the Health, Aging, and Body Composition studyPaul Holvoet
Center for Experimental Surgery and Anesthesiology, Katholieke Universiteit, Leuven, Belgium
Arterioscler Thromb Vasc Biol 23:1444-8. 2003..Therefore, we studied the association between high, predicted CHD risk and oxLDL in the Health ABC cohort... - Inflammatory markers and cardiovascular disease (The Health, Aging and Body Composition [Health ABC] Study)Matteo Cesari
Sticht Center on Aging, Wake Forest University Health Sciences, Winston Salem, North Carolina 27157, USA
Am J Cardiol 92:522-8. 2003..Thus, our findings suggest an important role for IL-6 and TNF-alpha in clinical as well as subclinical cardiovascular disease. In this study, CRP had a weaker association with cardiovascular disease than the cytokines... - Inflammatory markers and onset of cardiovascular events: results from the Health ABC studyMatteo Cesari
Sticht Center on Aging, Wake Forest University School of Medicine, Medical Center Blvd, Winston Salem, NC 27157, USA
Circulation 108:2317-22. 2003..CONCLUSIONS: Findings suggest that inflammatory markers are independent predictors of cardiovascular events in older persons... - Physical activity, exercise, and inflammatory markers in older adults: findings from the Health, Aging and Body Composition StudyLisa H Colbert
Laboratory of Epidemiology, Demography, and Biometry, National Institute on Aging, Bethesda, Maryland, USA
J Am Geriatr Soc 52:1098-104. 2004..To examine the association between physical activity and inflammatory markers, with consideration for body fatness and antioxidant use... - Inflammatory markers and incident mobility limitation in the elderlyBrenda W J H Penninx
Sticht Center on Aging, Section on Gerontology and Geriatric Medicine, Wake Forest University School of Medicine, Winston Salem, North Carolina, USA
J Am Geriatr Soc 52:1105-13. 2004..To examine the relationship between indicators of inflammation and the incidence of mobility limitation in older persons... - Lipoprotein peroxidation and mobility limitation: results from the Health, Aging, and Body Composition StudyMatteo Cesari
Department of Aging and Geriatric Research, College of Medicine, Institute on Aging, University of Florida, Gainesville 32608, USA
Arch Intern Med 165:2148-54. 2005..The aim of this study was to assess the predictive value of a lipoprotein peroxidation marker, oxidized low-density lipoprotein (oxLDL) for incident mobility limitation (ML)... - Cystatin C and mortality risk in the elderly: the health, aging, and body composition studyMichael G Shlipak
University of San Francisco, General Internal Medicine Section, VA Medical Center (111A1, 4150 Clement Street, San Francisco, CA 94121, USA
J Am Soc Nephrol 17:254-61. 2006..39], 0.95 [0.68 to 1.32], 1.11 [0.79 to 1.57], 1.16 [0.86 to 1.58]). Cystatin C is a strong, independent risk factor for mortality in the elderly. Future studies should investigate whether cystatin C has a role in clinical medicine... - Dietary protein intake is associated with lean mass change in older, community-dwelling adults: the Health, Aging, and Body Composition (Health ABC) StudyDenise K Houston
Sticht Center on Aging, Wake Forest University School of Medicine, Winston Salem, NC 27157 1207, USA
Am J Clin Nutr 87:150-5. 2008..Dietary surveys suggest that many older, community-dwelling adults consume insufficient dietary protein, which may contribute to the age-related loss of lean mass (LM)... - Kidney dysfunction and fatal cardiovascular disease--an association independent of atherosclerotic events: results from the Health, Aging, and Body Composition (Health ABC) studyRajat Deo
Division of Cardiology, Johns Hopkins Hospital, Baltimore, MD, USA
Am Heart J 155:62-8. 2008..We evaluated whether impaired kidney function predicted risk of fatal cardiovascular disease independent of prevalent and incident cardiovascular events... - Association of usual sleep duration with hypertension: the Sleep Heart Health StudyDaniel J Gottlieb
The Pulmonary Center, Boston University School of Medicine, 715 Albany Street, R 304, Boston, MA 02118 2394, USA
Sleep 29:1009-14. 2006..This study assesses the relationship between usual sleep duration and hypertension in a community-based cohort... - Kidney function as a predictor of loss of lean mass in older adults: health, aging and body composition studyLinda F Fried
Renal Section, Veterans Affairs Pittsburgh Healthcare System Pittsburgh, Pennsylvania 15240, USA
J Am Geriatr Soc 55:1578-84. 2007..To assess the association between kidney function and change in body composition in older individuals... - Factors associated with impaired appetite in well-functioning community-dwelling older adultsJung Sun Lee
Department of Foods and Nutrition, University of Georgia, Athens, GA 30602, USA
J Nutr Elder 26:27-43. 2006..5 (1.6- 4.1)), poor self-reported health (2.4 (1.7-3.2)), current smoking, chewing problems, reported visual impairment, weight loss since age 50, and log (TNF-alpha) were significantly related to impaired appetite... - Anxiety symptoms and decline in physical function over 5 years in the health, aging and body composition studyKala M Mehta
Division of Geriatrics, Department of Psychiatry, University of California at San Francisco, San Francisco, California, USA
J Am Geriatr Soc 55:265-70. 2007..To examine the relationship between anxiety and functional decline... - Cognitive function, gait speed decline, and comorbidities: the health, aging and body composition studyHal H Atkinson
Department of Internal Medicine, Section on Gerontology and Geriatric Medicine, Claude D Pepper Older Americans Independence Center, Wake Forest University School of Medicine, Winston Salem, North Carolina 27157, USA
J Gerontol A Biol Sci Med Sci 62:844-50. 2007..This study examines the relationship between cognitive function and subsequent gait speed decline among high-functioning older adults... - Psychosocial risk factors and the metabolic syndrome in elderly persons: findings from the Health, Aging and Body Composition studyNicole Vogelzangs
Department of Psychiatry and Institute for Research in Extramural Medicine, VU University Medical Center, Amsterdam, The Netherlands
J Gerontol A Biol Sci Med Sci 62:563-9. 2007..This study investigated the cross-sectional relationship between psychosocial risk factors and the metabolic syndrome in a community-based sample of older persons... - Limited literacy and mortality in the elderly: the health, aging, and body composition studyRebecca L Sudore
University of California, San Francisco, CA 94121, USA
J Gen Intern Med 21:806-12. 2006..While limited literacy is common and its prevalence increases with age, no prospective study has assessed whether limited literacy is associated with mortality in older adults... - Enhanced risk for Alzheimer disease in persons with type 2 diabetes and APOE epsilon4: the Cardiovascular Health Study Cognition StudyFumiko Irie
Laboratory of Epidemiology, Demography, and Biometry, National Institute on Aging, 7201 Wisconsin Ave, Bethesda, MD, USA
Arch Neurol 65:89-93. 2008..Diabetes and the apolipoprotein E epsilon4 allele (APOE epsilon4) increase the risk for Alzheimer disease (AD). We hypothesize that APOE epsilon4 may modify the risk for AD in individuals with diabetes... - Lifestyle factors and incident mobility limitation in obese and non-obese older adultsAnnemarie Koster
Department of Health Care Studies, Medical Sociology Section, Universiteit Maastricht, Maastricht, The Netherlands
Obesity (Silver Spring) 15:3122-32. 2007..This study examines the association between incident mobility limitation and 4 lifestyle factors: smoking, alcohol intake, physical activity, and diet in well-functioning obese (n = 667) and non-obese (n = 2027) older adults...
Research Grants
- Exceptional aging: 12 year trajectories to functionAnne Newman; Fiscal Year: 2007..This study is a critical step towards the identification of the targets and the time points for intervention to preserve function in old age. ..
- THE SLEEP HEART HEALTH STUDYAnne Newman; Fiscal Year: 2007..Accomplishing these goals will provide important information concerning the public health impact of SDB. ..
- Families of cohort survivors over 90 - Study CenterAnne Newman; Fiscal Year: 2007....
- EPIDEMIOLOGY OF CORONARY CALCIFICATION IN THE ELDERLYAnne Newman; Fiscal Year: 2005..abstract_text> ..