Anne B Newman

Summary

Affiliation: University of Pittsburgh
Country: USA

Publications

  1. ncbi request reprint Dementia and Alzheimer's disease incidence in relationship to cardiovascular disease in the Cardiovascular Health Study cohort
    Anne B Newman
    Department of Epidemiology, University of Pittsburgh, Pittsburgh, Pennsylvania 15213, USA
    J Am Geriatr Soc 53:1101-7. 2005
  2. pmc Long-term function in an older cohort--the cardiovascular health study all stars study
    Anne B Newman
    Department ofEpidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania 15213, USA
    J Am Geriatr Soc 57:432-40. 2009
  3. pmc Total and cause-specific mortality in the cardiovascular health study
    Anne B Newman
    Departments of Epidemiology and Medicine, University of Pittsburgh, 130 North Bellefield Avenue Room 532, Pittsburgh, PA 15213, USA
    J Gerontol A Biol Sci Med Sci 64:1251-61. 2009
  4. pmc The relationship of reduced peripheral nerve function and diabetes with physical performance in older white and black adults: the Health, Aging, and Body Composition (Health ABC) study
    Elsa S Strotmeyer
    Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
    Diabetes Care 31:1767-72. 2008
  5. ncbi request reprint Weight change and the conservation of lean mass in old age: the Health, Aging and Body Composition Study
    Anne B Newman
    Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA 15213, USA
    Am J Clin Nutr 82:872-8; quiz 915-6. 2005
  6. pmc Sensory and motor peripheral nerve function and lower-extremity quadriceps strength: the health, aging and body composition study
    Elsa S Strotmeyer
    Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania 15213, USA
    J Am Geriatr Soc 57:2004-10. 2009
  7. pmc Central nervous system medication use and incident mobility limitation in community elders: the Health, Aging, and Body Composition study
    Robert M Boudreau
    Department of Epidemiology, University of Pittsburgh, PA 15213, USA
    Pharmacoepidemiol Drug Saf 18:916-22. 2009
  8. pmc Muscle strength, mass, and quality in older men and women with knee osteoarthritis
    Molly B Conroy
    University of Pittsburgh, Pittsburgh, Pennsylvania, USA
    Arthritis Care Res (Hoboken) 64:15-21. 2012
  9. pmc Self-reported napping and duration and quality of sleep in the lifestyle interventions and independence for elders pilot study
    Jennifer L Picarsic
    Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania 15213, USA
    J Am Geriatr Soc 56:1674-80. 2008
  10. pmc Subjective and objective sleep quality in patients on conventional thrice-weekly hemodialysis: comparison with matched controls from the sleep heart health study
    Mark L Unruh
    Renal Electrolyte Division, University of Pittsburgh Medical Center, Pittsburgh, PA 15261, USA
    Am J Kidney Dis 52:305-13. 2008

Collaborators

Detail Information

Publications149 found, 100 shown here

  1. ncbi request reprint Dementia and Alzheimer's disease incidence in relationship to cardiovascular disease in the Cardiovascular Health Study cohort
    Anne B Newman
    Department of Epidemiology, University of Pittsburgh, Pittsburgh, Pennsylvania 15213, USA
    J Am Geriatr Soc 53:1101-7. 2005
    ..To determine whether coronary artery disease, peripheral arterial disease (PAD), or noninvasive markers of cardiovascular disease (CVD) predict the onset of dementia and Alzheimer's disease (AD)...
  2. pmc Long-term function in an older cohort--the cardiovascular health study all stars study
    Anne B Newman
    Department ofEpidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania 15213, USA
    J Am Geriatr Soc 57:432-40. 2009
    ..To evaluate shared and unique risk factors for maintaining physical and cognitive function into the ninth decade and beyond...
  3. pmc Total and cause-specific mortality in the cardiovascular health study
    Anne B Newman
    Departments of Epidemiology and Medicine, University of Pittsburgh, 130 North Bellefield Avenue Room 532, Pittsburgh, PA 15213, USA
    J Gerontol A Biol Sci Med Sci 64:1251-61. 2009
    ..Shared risk factors could be targeted for prevention of premature death and the study of longevity...
  4. pmc The relationship of reduced peripheral nerve function and diabetes with physical performance in older white and black adults: the Health, Aging, and Body Composition (Health ABC) study
    Elsa S Strotmeyer
    Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
    Diabetes Care 31:1767-72. 2008
    ..Poor peripheral nerve function is prevalent in diabetes and older populations, and it has great potential to contribute to poor physical performance...
  5. ncbi request reprint Weight change and the conservation of lean mass in old age: the Health, Aging and Body Composition Study
    Anne B Newman
    Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA 15213, USA
    Am J Clin Nutr 82:872-8; quiz 915-6. 2005
    ..Weight loss may contribute to the loss of lean mass with age...
  6. pmc Sensory and motor peripheral nerve function and lower-extremity quadriceps strength: the health, aging and body composition study
    Elsa S Strotmeyer
    Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania 15213, USA
    J Am Geriatr Soc 57:2004-10. 2009
    ..To determine whether sensory and motor nerve function is associated cross-sectionally with quadriceps or ankle dorsiflexion strength in an older community-based population...
  7. pmc Central nervous system medication use and incident mobility limitation in community elders: the Health, Aging, and Body Composition study
    Robert M Boudreau
    Department of Epidemiology, University of Pittsburgh, PA 15213, USA
    Pharmacoepidemiol Drug Saf 18:916-22. 2009
    ..To evaluate whether CNS medication use in older adults was associated with a higher risk of future incident mobility limitation...
  8. pmc Muscle strength, mass, and quality in older men and women with knee osteoarthritis
    Molly B Conroy
    University of Pittsburgh, Pittsburgh, Pennsylvania, USA
    Arthritis Care Res (Hoboken) 64:15-21. 2012
    ..To examine the relationship between knee osteoarthritis (OA) and muscle parameters in a biracial cohort of older adults...
  9. pmc Self-reported napping and duration and quality of sleep in the lifestyle interventions and independence for elders pilot study
    Jennifer L Picarsic
    Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania 15213, USA
    J Am Geriatr Soc 56:1674-80. 2008
    ..To determine the prevalence of self-reported napping and its association with subjective nighttime sleep duration and quality, as measured according to sleep-onset latency and sleep efficiency...
  10. pmc Subjective and objective sleep quality in patients on conventional thrice-weekly hemodialysis: comparison with matched controls from the sleep heart health study
    Mark L Unruh
    Renal Electrolyte Division, University of Pittsburgh Medical Center, Pittsburgh, PA 15261, USA
    Am J Kidney Dis 52:305-13. 2008
    ..It therefore is uncertain whether poor sleep quality in the HD population reflects age, chronic health conditions, or effects of conventional HD therapy...
  11. pmc Gait speed predicts decline in attention and psychomotor speed in older adults: the health aging and body composition study
    Marco Inzitari
    Department of Medicine, Division of Geriatric Medicine, University of Pittsburgh, Pittsburgh, PA 15213, USA
    Neuroepidemiology 29:156-62. 2007
    ..Gait speed is cross-sectionally associated with attention and psychomotor speed in older community dwellers. It is unclear if gait speed predicts decline in these cognitive domains over time...
  12. ncbi request reprint Association of long-distance corridor walk performance with mortality, cardiovascular disease, mobility limitation, and disability
    Anne B Newman
    Department of Epidemiology, Physical Therapy, University of Pittsburgh, Pittsburgh, PA 15213, USA
    JAMA 295:2018-26. 2006
    ..Extended walking tests have been examined as outcome predictors in medically ill populations but not in community-dwelling older adults...
  13. doi request reprint Incident physical disability in people with lower extremity peripheral arterial disease: the role of cardiovascular disease
    Jennifer S Brach
    Department of Physical Therapy, School of Health and Rehabilitation Sciences, University of Pittsburgh, Pittsburgh, PA 15260, USA
    J Am Geriatr Soc 56:1037-44. 2008
    ..To evaluate the risk of incident physical disability and the decline in gait speed over a 6-year follow-up associated with a low ankle-arm index (AAI) in older adults...
  14. pmc Number and dosage of central nervous system medications on recurrent falls in community elders: the Health, Aging and Body Composition study
    Joseph T Hanlon
    Department of Medicine, Geriatrics, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15213, USA
    J Gerontol A Biol Sci Med Sci 64:492-8. 2009
    ..The study objective was to evaluate whether multiple- or high-dose CNS medication use in older adults was associated with a higher risk of recurrent (>or=2) falls...
  15. ncbi request reprint Obesity, regional body fat distribution, and the metabolic syndrome in older men and women
    Bret H Goodpaster
    Department of Medicine, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA
    Arch Intern Med 165:777-83. 2005
    ..We determined whether patterns of regional fat deposition are associated with metabolic syndrome in older adults...
  16. pmc 4G/5G plasminogen activator inhibitor-1 polymorphisms and haplotypes are associated with pneumonia
    Sachin Yende
    CRISMA Laboratory Clinical Research, Investigation, and Systems Modeling of Acute Illness, Department of Critical Care Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
    Am J Respir Crit Care Med 176:1129-37. 2007
    ..Whether variation within the PAI-1 gene is associated with increased susceptibility to infection is unknown...
  17. pmc Poor sleep is associated with poorer physical performance and greater functional limitations in older women
    Suzanne E Goldman
    Department of Epidemiology, University ofPittsburgh, Pittsburgh, PA, USA
    Sleep 30:1317-24. 2007
    ..This study examined the association between disturbed sleep and poorer daytime function in older women...
  18. ncbi request reprint Kidney function predicts the rate of bone loss in older individuals: the Cardiovascular Health Study
    Linda F Fried
    VA Pittsburgh Healthcare System, Pittsburgh, PA 15240, USA
    J Gerontol A Biol Sci Med Sci 61:743-8. 2006
    ....
  19. ncbi request reprint Reduced peripheral nerve function is related to lower hip BMD and calcaneal QUS in older white and black adults: the Health, Aging, and Body Composition Study
    Elsa S Strotmeyer
    Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania 15213, USA
    J Bone Miner Res 21:1803-10. 2006
    ..Poor peripheral nerve function may directly affect bone...
  20. ncbi request reprint Multitasking: association between poorer performance and a history of recurrent falls
    Kimberly A Faulkner
    Department of Epidemiology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
    J Am Geriatr Soc 55:570-6. 2007
    ..To examine the association between poorer performance on concurrent walking and reaction time and recurrent falls...
  21. ncbi request reprint Association between infant birth weight and maternal cardiovascular risk factors in the health, aging, and body composition study
    Janet M Catov
    Department of Epidemiology, University of Pittsburgh Graduate School of Public Health, Pittsburgh, PA 15261, USA
    Ann Epidemiol 17:36-43. 2007
    ....
  22. pmc Association of a Modified Physiologic Index with mortality and incident disability: the Health, Aging, and Body Composition study
    Jason L Sanders
    Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Bellefield Professional Building 4th Floor, 130 North Bellefield Avenue, Pittsburgh, PA 15213, USA
    J Gerontol A Biol Sci Med Sci 67:1439-46. 2012
    ..We studied the associations of a Modified Physiologic Index (systolic blood pressure, forced vital capacity, Digit Symbol Substitution Test score, serum cystatin-C, serum fasting glucose) with mortality and incident disability...
  23. pmc Association between lower digit symbol substitution test score and slower gait and greater risk of mortality and of developing incident disability in well-functioning older adults
    Caterina Rosano
    Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennylvania, USA
    J Am Geriatr Soc 56:1618-25. 2008
    ....
  24. pmc Long-term retention of older adults in the Cardiovascular Health Study: implications for studies of the oldest old
    Elsa S Strotmeyer
    Center for Aging and Population Health, Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Room 515, Pittsburgh, Pennsylvania 15213, USA
    J Am Geriatr Soc 58:696-701. 2010
    ..To describe retention according to age and visit type (clinic, home, telephone) and to determine characteristics associated with visit types for a longitudinal epidemiological study in older adults...
  25. ncbi request reprint Nontraumatic fracture risk with diabetes mellitus and impaired fasting glucose in older white and black adults: the health, aging, and body composition study
    Elsa S Strotmeyer
    Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA 15213, USA
    Arch Intern Med 165:1612-7. 2005
    ..Diabetes mellitus (DM) and related complications may increase clinical fracture risk in older adults...
  26. pmc Psychomotor speed and functional brain MRI 2 years after completing a physical activity treatment
    Caterina Rosano
    Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, 130 North Bellefield Street, Room 512, Pittsburgh, PA 15213, USA
    J Gerontol A Biol Sci Med Sci 65:639-47. 2010
    ..It is not known whether these associations are also significant for longer-term adherence to moderate-intensity activities...
  27. ncbi request reprint Inflammatory markers and incident fracture risk in older men and women: the Health Aging and Body Composition Study
    Jane A Cauley
    Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania 15261, USA
    J Bone Miner Res 22:1088-95. 2007
    ..We tested this hypothesis in relationship to fractures in 2985 men and women enrolled in the Health ABC study. Results showed that subjects with the greatest number of inflammatory markers have the highest risk of fracture...
  28. ncbi request reprint Periodontal disease and weight loss in older adults
    Robert J Weyant
    Department of Dental Public Health, University of Pittsburgh, Pittsburgh, Pennsylvannia 15261, USA
    J Am Geriatr Soc 52:547-53. 2004
    ..To determine the association between periodontal disease and weight loss in an elderly cohort...
  29. pmc Aortic pulse wave velocity predicts focal white matter hyperintensities in a biracial cohort of older adults
    Caterina Rosano
    Department of Epidemiology, University of Pittsburgh, Pittsburgh, PA, USA
    Hypertension 61:160-5. 2013
    ....
  30. pmc Relationship between vitamin B12 and sensory and motor peripheral nerve function in older adults
    Kira Leishear
    Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
    J Am Geriatr Soc 60:1057-63. 2012
    ..To examine whether deficient B12 status or low serum B12 levels are associated with worse sensory and motor peripheral nerve function in older adults...
  31. ncbi request reprint Geographic variations in stroke incidence and mortality among older populations in four US communities
    Aiman El-Saed
    Department of Epidemiology, University of Pittsburgh, 130 N Bellefield Ave, Rm 405, Pittsburgh, PA 15213, USA
    Stroke 37:1975-9. 2006
    ..The purpose of this study was to compare stroke incidence and mortality rates in 4 US communities...
  32. pmc Effect of central nervous system medication use on decline in cognition in community-dwelling older adults: findings from the Health, Aging And Body Composition Study
    Rollin M Wright
    Department of Medicine, University of Pittsburgh, Pennsylvania 15213, USA
    J Am Geriatr Soc 57:243-50. 2009
    ..To evaluate whether combined use of multiple central nervous system (CNS) medications over time is associated with cognitive change...
  33. ncbi request reprint Short-term weight changes in community-dwelling older adults: the Health, Aging, and Body Composition Weight Change Substudy
    Jung Sun Lee
    University of Pittsburgh, Pittsburgh, PA 15213, USA
    Am J Clin Nutr 82:644-50. 2005
    ..The frequency and short-term natural history of weight loss in community-dwelling older adults have not been described. Unintentional weight loss may be more likely to continue than intentional weight loss...
  34. ncbi request reprint Ethnic differences in the frequency and circumstances of falling in older community-dwelling women
    Kimberly A Faulkner
    Department of Epidemiology, University of Pittsburgh, Pittsburgh, Pennsylvania 15261, USA
    J Am Geriatr Soc 53:1774-9. 2005
    ..To examine ethnic differences in fall rates and fall circumstances in older community-dwelling Caucasian and African-American women...
  35. ncbi request reprint Systemic inflammatory markers, periodontal diseases, and periodontal infections in an elderly population
    Walter A Bretz
    Division of Pediatric and Developmental Science, University of Pittsburgh, PA 15261, USA
    J Am Geriatr Soc 53:1532-7. 2005
    ..To study the levels of systemic markers for inflammation with parameters of periodontal diseases in older people...
  36. ncbi request reprint White matter grade and ventricular volume on brain MRI as markers of longevity in the cardiovascular health study
    Lewis H Kuller
    Department of Epidemiology, University of Pittsburgh Graduate School of Public Health, 130 N Bellefield Ave, Rm 550, Pittsburgh, PA 15213, United States
    Neurobiol Aging 28:1307-15. 2007
    ..Low WMG and VG on MRI is a powerful determinant of long-term survival among older individuals...
  37. ncbi request reprint The association between physical function and lifestyle activity and exercise in the health, aging and body composition study
    Jennifer S Brach
    Department of Physical Therapy, School of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvannia 15260, USA
    J Am Geriatr Soc 52:502-9. 2004
    ..To determine whether older adults who exercise demonstrate higher levels of physical function than those who do not exercise but are physically active throughout the day...
  38. ncbi request reprint Race and sex differences in age-related hearing loss: the Health, Aging and Body Composition Study
    Elizabeth P Helzner
    Department of Epidemiology, University of Pittsburgh, Pittsburgh, Pennsylvania 15261, USA
    J Am Geriatr Soc 53:2119-27. 2005
    ..To determine the prevalence of and risk factors for hearing loss in a sample of 2,052 older adults (aged 73-84; 46.9% male, 37.3% black) enrolled in the Health, Aging and Body Composition (Health ABC) Study...
  39. ncbi request reprint Sleep apnea in patients on conventional thrice-weekly hemodialysis: comparison with matched controls from the Sleep Heart Health Study
    Mark L Unruh
    University of Pittsburgh Medical Center, Renal Electrolyte Division, 3550 Terrace Street, A909 Scaife Hall, Pittsburgh, PA 15261, USA
    J Am Soc Nephrol 17:3503-9. 2006
    ..The potential mechanisms for the higher likelihood of SDB in the HD population must be identified to provide specific prevention and therapy...
  40. ncbi request reprint Sarcopenia: alternative definitions and associations with lower extremity function
    Anne B Newman
    Division of Geriatric Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania 15213, USA
    J Am Geriatr Soc 51:1602-9. 2003
    ....
  41. pmc Change in cardiovascular risk factors with progression of kidney disease
    Linda F Fried
    Renal Section, VA Pittsburgh Healthcare System, Pittsburgh, PA 15240, USA
    Am J Nephrol 29:334-41. 2009
    ..We evaluated the change in lipids, inflammatory and procoagulant biomarkers with decline in kidney function in a nested case-cohort study in the Cardiovascular Health Study, a community-based study of adults aged >65 years...
  42. ncbi request reprint Weight change, weight change intention, and the incidence of mobility limitation in well-functioning community-dwelling older adults
    Jung Sun Lee
    Healthy Aging Research Program, Department of Epidemiology, University of Pittsburgh, PA 15213, USA
    J Gerontol A Biol Sci Med Sci 60:1007-12. 2005
    ..The aim of this study was to determine whether weight, weight change, and weight change intention are associated with risk for mobility limitation in elderly persons...
  43. doi request reprint Association of cystatin C and depression in healthy elders: the health, aging and body composition study
    Evgueni Minev
    Renal Electrolyte Division, University of Pittsburgh School of Medicine, Pittsburgh, PA 15216, USA
    Nephron Clin Pract 116:c241-6. 2010
    ..We evaluated the association between kidney function and depression in the Health, Aging and Body Composition (Health ABC) study...
  44. pmc Parity and cardiovascular disease risk among older women: how do pregnancy complications mediate the association?
    Janet M Catov
    University of Pittsburgh, Department of Obstetrics, Gynecology and Reproductive Sciences, Pittsburgh PA 15213, USA
    Ann Epidemiol 18:873-9. 2008
    ..To determine whether parity is associated with increased risk of cardiovascular disease (CVD) after accounting for perinatal complications...
  45. pmc Slower gait, slower information processing and smaller prefrontal area in older adults
    Caterina Rosano
    Department of Epidemiology, Graduate School of Public Health, 130 N Bellefield Avenue, Pittsburgh, PA 15213, USA
    Age Ageing 41:58-64. 2012
    ..Understanding slowing gait could help improve function in older age. We examine whether the association between smaller PFAv and slower gait is explained by lower performance on numerous neuropsychological tests...
  46. ncbi request reprint Strength, but not muscle mass, is associated with mortality in the health, aging and body composition study cohort
    Anne B Newman
    University of Pittsburgh, Department of Epidemiology, 130 N Bellefield Avenue, Room 532, Pittsburgh, PA 15213, USA
    J Gerontol A Biol Sci Med Sci 61:72-7. 2006
    ..Although muscle strength and mass are highly correlated, the relationship between direct measures of low muscle mass (sarcopenia) and strength in association with mortality has not been examined...
  47. ncbi request reprint Alternative definitions of sarcopenia, lower extremity performance, and functional impairment with aging in older men and women
    Matthew J Delmonico
    Department of Epidemiology, University of Pittsburgh, Pittsburgh, Pennsylvania 15213, USA
    J Am Geriatr Soc 55:769-74. 2007
    ..To compare two methods for classifying an individual as sarcopenic for predicting decline in physical function in the Health, Aging and Body Composition Study...
  48. pmc Diabetes mellitus and gait dysfunction: possible explanatory factors
    Jennifer S Brach
    Department of Physical Therapy, School of Health and Rehabilitation Sciences, University of Pittsburgh, 6035 Forbes Tower, Pittsburgh, PA 15260, USA
    Phys Ther 88:1365-74. 2008
    ..Limited information regarding potential explanatory factors for this association exists. This study examined the association between diabetes and gait characteristics in older adults and explored potential explanatory factors...
  49. pmc Impact of health perception, balance perception, fall history, balance performance, and gait speed on walking activity in older adults
    Jaime B Talkowski
    Department of Physical Therapy, University of Pittsburgh, 6035 Forbes Tower, Pittsburgh, PA 15260, USA
    Phys Ther 88:1474-81. 2008
    ....
  50. pmc Caregiving, mortality, and mobility decline: the Health, Aging, and Body Composition (Health ABC) Study
    Lisa Fredman
    Department of Epidemiology, Boston University School of Public Health, Boston, MA 02118, USA
    Arch Intern Med 168:2154-62. 2008
    ..We hypothesized that caregivers may be more physically active than noncaregivers, which may protect them from health decline...
  51. pmc Gait variability is associated with subclinical brain vascular abnormalities in high-functioning older adults
    Caterina Rosano
    Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA 15213, USA
    Neuroepidemiology 29:193-200. 2007
    ..The brain anatomical correlates of gait variability have not been studied in high-functioning community-dwelling older adults...
  52. ncbi request reprint Skeletal muscle fatigue, strength, and quality in the elderly: the Health ABC Study
    Andreas Katsiaras
    Division of Endocrinology and Metabolism, Department of Medicine, University of Pittsburgh, Pennsylvania, USA
    J Appl Physiol 99:210-6. 2005
    ..In conclusion, older men were more fatigue resistant than women, although in both men and women greater fatigue was not related to muscle weakness...
  53. pmc Health and function of participants in the Long Life Family Study: A comparison with other cohorts
    Anne B Newman
    University of Pittsburgh, Graduate School of Public Health, Department of Epidemiology, Center for Aging and Population Health, PA 15213, USA
    Aging (Albany NY) 3:63-76. 2011
    ..These findings suggest several priority phenotypes for inclusion in future genetic analysis to identify loci contributing to exceptional survival...
  54. pmc The influence of pre-existing diabetes mellitus on the host immune response and outcome of pneumonia: analysis of two multicentre cohort studies
    Sachin Yende
    Clinical Research, Investigation, and Systems Modeling of Acute Illness CRISMA Laboratory, University of Pittsburgh, Pittsburgh, PA, USA
    Thorax 65:870-7. 2010
    ..Although diabetes mellitus is implicated in susceptibility to infection, the association of diabetes with the subsequent course and outcome is unclear...
  55. ncbi request reprint Kidney function as a predictor of noncardiovascular mortality
    Linda F Fried
    VA Pittsburgh Healthcare System and Renal Electrolyte Division, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15240, USA
    J Am Soc Nephrol 16:3728-35. 2005
    ..Kidney function predicts noncardiovascular mortality from multiple causes in the elderly. Further research is needed to understand the mechanisms and evaluate interventions to reduce the high mortality rate in chronic kidney disease...
  56. ncbi request reprint Neck and shoulder pain in 70- to 79-year-old men and women: findings from the Health, Aging and Body Composition Study
    Molly T Vogt
    Department of Orthopaedic Surgery, University of Pittsburgh, Pittsburgh, PA 15213, USA
    Spine J 3:435-41. 2003
    ..Musculoskeletal pain in the cervicobrachial region is considered a major health problem among adults of working age, but little is known about the impact of this pain in the elderly...
  57. pmc Plasma beta amyloid level and depression in older adults
    Andrea L Metti
    Center for Aging and Population Health, Department of Epidemiology, University of Pittsburgh, Pittsburgh, PA 15213, USA
    J Gerontol A Biol Sci Med Sci 68:74-9. 2013
    ..Older adults with depression have an increased risk of developing dementia. Low plasma beta-amyloid 42 (Aβ42) and Aβ42/Aβ40 have emerged as promising biomarkers of dementia. The association between depression and plasma Aβ is unclear...
  58. pmc Leukocyte telomere length is associated with noninvasively measured age-related disease: The Cardiovascular Health Study
    Jason L Sanders
    School of Medicine, University of Pittsburgh, Pittsburgh, PA 15213, USA
    J Gerontol A Biol Sci Med Sci 67:409-16. 2012
    ....
  59. ncbi request reprint Chronic kidney disease and functional limitation in older people: health, aging and body composition study
    Linda F Fried
    Department of Veterans Affairs Pittsburgh Healthcare System, University Drive, Pittsburgh, PA 15240, USA
    J Am Geriatr Soc 54:750-6. 2006
    ..To assess whether chronic kidney disease (CKD) is independently associated with incident physical-function limitation...
  60. pmc Sleep-disordered breathing in the National Football League
    Thomas B Rice
    Department of Medicine, University of Pittsburgh, Pittsburgh, PA, USA
    Sleep 33:819-24. 2010
    ..NFL players have a higher prevalence of hypertension, and we sought to determine the prevalence of SDB among players the NFL and the associations of SDB with anthropometric measures and cardiovascular risk factors...
  61. ncbi request reprint The loss of skeletal muscle strength, mass, and quality in older adults: the health, aging and body composition study
    Bret H Goodpaster
    Department of Medicine, MUH N809, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA
    J Gerontol A Biol Sci Med Sci 61:1059-64. 2006
    ..The loss of muscle mass is considered to be a major determinant of strength loss in aging. However, large-scale longitudinal studies examining the association between the loss of mass and strength in older adults are lacking...
  62. pmc The effects of age on inflammatory and coagulation-fibrinolysis response in patients hospitalized for pneumonia
    Sachin Kale
    The Clinical Research, Investigation, and Systems Modeling of Acute Illness Laboratory, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America
    PLoS ONE 5:e13852. 2010
    ..To determine whether inflammatory and hemostasis response in patients hospitalized for pneumonia varies by age and whether these differences explain higher mortality in the elderly...
  63. pmc Successful skeletal aging: a marker of low fracture risk and longevity. The Study of Osteoporotic Fractures (SOF)
    Jane A Cauley
    University of Pittsburgh, Department of Epidemiology, Pittsburgh, Pennsylvania 15261, USA
    J Bone Miner Res 24:134-43. 2009
    ..These women experienced a lower risk of fractures, disability, and mortality, suggesting that this phenotype may be a marker of successful aging...
  64. ncbi request reprint Association of kidney function with incident hip fracture in older adults
    Linda F Fried
    VA Pittsburgh Healthcare System, Pittsburgh, PA 15240, USA
    J Am Soc Nephrol 18:282-6. 2007
    ..Further studies are needed to evaluate potential mediators of this relationship and to assess whether interventions can decrease this risk...
  65. ncbi request reprint Weight-loss intention in the well-functioning, community-dwelling elderly: associations with diet quality, physical activity, and weight change
    Jung Sun Lee
    Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, 130 North Bellefield Avenue, 5th Floor, Pittsburgh, PA 15213, USA
    Am J Clin Nutr 80:466-74. 2004
    ..Many older adults desire to lose weight, yet the proportion with a health-related weight-loss indication, weight-loss strategies, and success is unknown...
  66. pmc Longitudinal study of muscle strength, quality, and adipose tissue infiltration
    Matthew J Delmonico
    Department of Epidemiology and Medicine, University of Pittsburgh, Pittsburgh, PA, USA
    Am J Clin Nutr 90:1579-85. 2009
    ..Sarcopenia is thought to be accompanied by increased muscle fat infiltration. However, no longitudinal studies have examined concomitant changes in muscle mass, strength, or fat infiltration in older adults...
  67. ncbi request reprint Preterm delivery and later maternal cardiovascular disease risk
    Janet M Catov
    Department of Epidemiology, University of Pittsburgh Graduate School of Public Health, Pittsburgh, PA 15261, USA
    Epidemiology 18:733-9. 2007
    ..Women who have delivered a preterm infant are at elevated risk for cardiovascular disease (CVD), but mechanisms for this association are not understood...
  68. doi request reprint Subjective and objective sleep quality and aging in the sleep heart health study
    Mark L Unruh
    Renal Electrolyte Division, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania 15261, USA
    J Am Geriatr Soc 56:1218-27. 2008
    ..To examine the extent to which subjective and objective sleep quality are related to age independent of chronic health conditions...
  69. ncbi request reprint Relationship between coronary artery calcification and other measures of subclinical cardiovascular disease in older adults
    Anne B Newman
    Division of Geriatric Medicine, University of Pittsburgh, PA 15213, USA
    Arterioscler Thromb Vasc Biol 22:1674-9. 2002
    ..In the Cardiovascular Health Study, subclinical cardiovascular disease (CVD) predicted CVD events in older adults. The extent to which this measure or its components reflect calcified coronary disease is unknown...
  70. pmc High blood pressure accelerates gait slowing in well-functioning older adults over 18-years of follow-up
    Caterina Rosano
    Department of Epidemiology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
    J Am Geriatr Soc 59:390-7. 2011
    ..To examine whether the association between hypertension and decline in gait speed is significant in well-functioning older adults and whether other health-related factors, such as brain, kidney, and heart function, can explain it...
  71. ncbi request reprint Focal atrophy and cerebrovascular disease increase dementia risk among cognitively normal older adults
    Caterina Rosano
    School of Public Health, Department of Epidemiology, University of Pittsburgh, Pennysylvania, USA
    J Neuroimaging 17:148-55. 2007
    ....
  72. ncbi request reprint The clock drawing test is an independent predictor of incident use of 24-hour care in a retirement community
    Laurie L Lavery
    Division of Geriatric Medicine, University of Pittsburgh, 3471 Fifth Ave, Suite 500, Pittsburgh, PA 15213, USA
    J Gerontol A Biol Sci Med Sci 60:928-32. 2005
    ..We examined the relationship between executive function, measured with a clock drawing protocol (CLOX1) designed to capture executive impairment, and incident need for increased level of care and total mortality...
  73. ncbi request reprint Common promoter polymorphisms of inflammation and thrombosis genes and longevity in older adults: the cardiovascular health study
    Alexander P Reiner
    Department of Epidemiology, University of Washington, Seattle, WA 98101, USA
    Atherosclerosis 181:175-83. 2005
    ..These findings suggest that modulators of fibrinolytic activity may have a generalized influence on aging, and merit further investigation in studies of genetic determinants of human longevity...
  74. ncbi request reprint Diabetes is associated independently of body composition with BMD and bone volume in older white and black men and women: The Health, Aging, and Body Composition Study
    Elsa S Strotmeyer
    Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania 15213, USA
    J Bone Miner Res 19:1084-91. 2004
    ..Diabetes predicted higher hip, whole body, and volumetric spine BMD, and lower spine bone volume, independent of body composition and fasting insulin...
  75. pmc Event-related functional magnetic resonance imaging investigation of executive control in very old individuals with mild cognitive impairment
    Caterina Rosano
    School of Public Health, Department of Epidemiology, University of Pittsburgh, Pittsburgh, Pennsylvania 15213, USA
    Biol Psychiatry 57:761-7. 2005
    ....
  76. pmc The burden of cardiovascular disease in the elderly: morbidity, mortality, and costs
    Ali Yazdanyar
    Center for Aging and Population Health, Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, 130 North Bellefield Avenue, Pittsburgh, PA 15213, USA
    Clin Geriatr Med 25:563-77, vii. 2009
    ..This article provides an overview of the epidemiology of CVD in older adults, including an assessment of the impact of CVD on mortality, morbidity, and health care costs...
  77. ncbi request reprint Strength and muscle quality in a well-functioning cohort of older adults: the Health, Aging and Body Composition Study
    Anne B Newman
    Department of Medicine, Division of Geriatric Medicine, University of Pittsburgh School of Medicine, 3520 5th Avenue, Suite 300, Pittsburgh, PA 15213, USA
    J Am Geriatr Soc 51:323-30. 2003
    ..To determine whether lower lean mass and higher fat mass have independent effects on the loss of strength and muscle quality in older adults and might explain part of the effect of age...
  78. pmc Stance time and step width variability have unique contributing impairments in older persons
    Jennifer S Brach
    Department of Physical Therapy, School of Health and Rehabilitation Sciences, University of Pittsburgh, Pittsburgh, PA 15260, United States
    Gait Posture 27:431-9. 2008
    ..Specific patterns of gait variability may imply different underlying causes. Types of gait variability should be specified. Interventions may be targeted at specific types of gait variability...
  79. ncbi request reprint Coronary artery calcium and physical function in older adults: the Cardiovascular Health Study
    Marco Inzitari
    Department of Medicine, Division of Geriatric Medicine, University of Pittsburgh, 130 N Bellefield St, Room 518, Pittsburgh, PA, USA
    J Gerontol A Biol Sci Med Sci 63:1112-8. 2008
    ..However, the association between CAC and physical function is unstudied...
  80. pmc Coronary artery calcium, carotid artery wall thickness, and cardiovascular disease outcomes in adults 70 to 99 years old
    Anne B Newman
    Department of Epidemiology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
    Am J Cardiol 101:186-92. 2008
    ..The CCA-IMT was more strongly related to stroke than CAC, but CAC was also a predictor of stroke...
  81. ncbi request reprint Walking performance and cardiovascular response: associations with age and morbidity--the Health, Aging and Body Composition Study
    Anne B Newman
    Division of Geriatric Medicine, Department of Medicine, University of Pittsburgh, Pennsylvania 15213, USA
    J Gerontol A Biol Sci Med Sci 58:715-20. 2003
    ..The long-distance corridor walk is a timed 400-meter walk test used to assess walking endurance in well-functioning men and women aged 70-79 in the Health, Aging and Body Composition Study...
  82. pmc Gait variability and the risk of incident mobility disability in community-dwelling older adults
    Jennifer S Brach
    Department of Physical Therapy, University of Pittsburgh, Division of Geriatric Medicine, Department of Epidemiology, Pittsburgh, PA 15260, USA
    J Gerontol A Biol Sci Med Sci 62:983-8. 2007
    ..Gait speed is a strong predictor of incident walking disability. The objective was to determine if gait variability adds to the prediction of incident mobility disability independent of gait speed...
  83. pmc Magnetization transfer imaging, white matter hyperintensities, brain atrophy and slower gait in older men and women
    Caterina Rosano
    University of Pittsburgh, Graduate School of Public Health, Pittsburgh, PA, USA
    Neurobiol Aging 31:1197-204. 2010
    ....
  84. ncbi request reprint Influence of marital status on physical activity levels among older adults
    Kelley K Pettee
    University of Pittsburgh, Pittsburgh, PA, USA
    Med Sci Sports Exerc 38:541-6. 2006
    ....
  85. ncbi request reprint Reciprocal influence of concurrent walking and cognitive testing on performance in older adults
    Kimberly A Faulkner
    University of Pittsburgh, 130 DeSoto Street, Parran 509, Pittsburgh, PA 15261, USA
    Gait Posture 24:182-9. 2006
    ..062). Findings suggest that walking requires significant cognitive resources among older adults and slower-walking adults and weaker adults may require higher cognitive loading while walking...
  86. pmc Leukocyte Telomere Length Is Not Associated With BMD, Osteoporosis, or Fracture in Older Adults: Results From the Health, Aging and Body Composition Study
    Jason L Sanders
    Medical Scientist Training Program, School of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
    J Bone Miner Res 24:1531-6. 2009
    ..TL is not associated with BMD, osteoporosis, or fracture in older men or women in this sample...
  87. pmc Cardiovascular disease is associated with greater incident dehydroepiandrosterone sulfate decline in the oldest old: the cardiovascular health study all stars study
    Jason L Sanders
    Department of Medicine, School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA
    J Am Geriatr Soc 58:421-6. 2010
    ..To describe cross-sectional and longitudinal associations with dehydroepiandrosterone sulfate (DHEAS) and change in DHEAS with age...
  88. pmc Special article: gait measures indicate underlying focal gray matter atrophy in the brain of older adults
    Caterina Rosano
    Department of Epidemiology, University of Pittsburgh, Pittsburgh, PA, USA
    J Gerontol A Biol Sci Med Sci 63:1380-8. 2008
    ..Our objective was to identify the spatial distribution of focal atrophy within mobility-related brain regions in relationship with quantitative gait characteristics...
  89. ncbi request reprint Decreased muscle strength and quality in older adults with type 2 diabetes: the health, aging, and body composition study
    Seok Won Park
    Department of Internal Medicine, Pochon CHA University, Pochon, Korea
    Diabetes 55:1813-8. 2006
    ..In conclusion, diabetes is associated with lower skeletal muscle strength and quality. These characteristics may contribute to the development of physical disability in older adults with diabetes...
  90. ncbi request reprint Factors associated with geographic variations in stroke incidence among older populations in four US communities
    Aiman El-Saed
    Department of Epidemiology, University of Pittsburgh, 130 N Bellefield Ave, Rm 405, Pittsburgh, PA 15213, USA
    Stroke 37:1980-5. 2006
    ..The purpose of this study was to study possible reasons for the lower stroke incidence in Allegheny County...
  91. pmc Physical performance and subsequent disability and survival in older adults with malignancy: results from the health, aging and body composition study
    Heidi D Klepin
    Comprehensive Cancer Center, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
    J Am Geriatr Soc 58:76-82. 2010
    ..To evaluate objective physical performance measures as predictors of survival and subsequent disability in older patients with cancer...
  92. ncbi request reprint Volumetric BMD and vascular calcification in middle-aged women: the Study of Women's Health Across the Nation
    Ghada N Farhat
    Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, PA 15261, USA
    J Bone Miner Res 21:1839-46. 2006
    ..Lower vBMD was related to high AC, but not to CAC, independent of age and shared risk factors between osteoporosis and cardiovascular disease...
  93. pmc The reliability and validity of measures of gait variability in community-dwelling older adults
    Jennifer S Brach
    Department of Physical Therapy, University of Pittsburgh, Pittsburgh, PA 15260, USA
    Arch Phys Med Rehabil 89:2293-6. 2008
    ..To examine the test-retest reliability and concurrent validity of variability of gait characteristics...
  94. ncbi request reprint Hearing sensitivity and bone mineral density in older adults: the Health, Aging and Body Composition Study
    Elizabeth P Helzner
    Department of Epidemiology, University of Pittsburgh, Pittsburgh, PA, USA
    Osteoporos Int 16:1675-82. 2005
    ..These results suggest that axial and appendicular bone parameters may be modestly associated with hearing loss in older men, but not in women...
  95. ncbi request reprint Coronary artery calcium: associations with brain magnetic resonance imaging abnormalities and cognitive status
    Caterina Rosano
    Department of Epidemiology, School of Public Health, University of Pittsburgh, 130 N Bellefield Avenue, Pittsburgh, PA 15260, USA
    J Am Geriatr Soc 53:609-15. 2005
    ..To evaluate the association between coronary atherosclerosis and subclinical brain magnetic resonance imaging (MRI) abnormalities and between coronary atherosclerosis and abnormal cognitive function (dementia/mild cognitive impairment)...
  96. ncbi request reprint Cardiovascular disease and risk of Alzheimer's disease
    Caterina Rosano
    Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA 15213, USA
    Neurol Res 28:612-20. 2006
    ..This review will examine the evidence for these associations and possible pathogenetic pathways. Clinical relevance and implications of these associations will also be discussed...
  97. pmc An overview of the design, implementation, and analyses of longitudinal studies on aging
    Anne B Newman
    Center for Aging and Population Health, Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania 15213, USA
    J Am Geriatr Soc 58:S287-91. 2010
    ..Analysis of longitudinal data requires approaches that account for inevitable missing data. New studies should take advantage of the experience obtained from longitudinal studies on aging already conducted...
  98. ncbi request reprint Physical activity and functional status in community-dwelling older women: a 14-year prospective study
    Jennifer S Brach
    Department of Physical Therapy, School of Health and Rehabilitation Sciences, University of Pittsburgh, 6035 Forbes Tower, Pittsburgh, PA 15260, USA
    Arch Intern Med 163:2565-71. 2003
    ..Short-term prospective studies have shown physical activity to be related to functional status. To our knowledge, the association between physical activity levels and functional status over a longer period has not been established...
  99. ncbi request reprint Inflammatory markers and incident mobility limitation in the elderly
    Brenda W J H Penninx
    Sticht Center on Aging, Section on Gerontology and Geriatric Medicine, Wake Forest University School of Medicine, Winston Salem, North Carolina, USA
    J Am Geriatr Soc 52:1105-13. 2004
    ..To examine the relationship between indicators of inflammation and the incidence of mobility limitation in older persons...
  100. pmc Association between nighttime sleep and napping in older adults
    Suzanne E Goldman
    Department of Neurology, Sleep Disorders Program, Vanderbilt University Medical Center, Nashville, TN 37232, USA
    Sleep 31:733-40. 2008
    ..Napping might indicate deficiencies in nighttime sleep, but the relationship is not well defined. We assessed the association of nighttime sleep duration and fragmentation with subsequent daytime sleep...
  101. pmc Fetuin-A and incident diabetes mellitus in older persons
    Joachim H Ix
    Division of Nephrology and Hypertension, Department of Medicine, University of California, San Diego, and San Diego Veterans Affairs Healthcare System, 3350 La Jolla Village Dr, Mail Code 111 H, San Diego, CA 92161, USA
    JAMA 300:182-8. 2008
    ..In prior cross-sectional studies in humans, higher fetuin-A levels were associated with insulin resistance. However, the longitudinal association of fetuin-A with incident type 2 diabetes mellitus is unknown...