A B Newman

Summary

Affiliation: University of Pittsburgh
Country: USA

Publications

  1. ncbi request reprint Ankle-arm index as a predictor of cardiovascular disease and mortality in the Cardiovascular Health Study. The Cardiovascular Health Study Group
    A B Newman
    University of Pittsburgh, Pittsburgh, PA, USA
    Arterioscler Thromb Vasc Biol 19:538-45. 1999
  2. ncbi request reprint Relation of sleep-disordered breathing to cardiovascular disease risk factors: the Sleep Heart Health Study
    A B Newman
    University of Pittsburgh, 3520 Fifth Avenue, Suite 300, Pittsburgh, PA 15213, USA
    Am J Epidemiol 154:50-9. 2001
  3. ncbi request reprint Associations of subclinical cardiovascular disease with frailty
    A B Newman
    The University of Pittsburgh, Pennsylvania, USA
    J Gerontol A Biol Sci Med Sci 56:M158-66. 2001
  4. pmc Self-reported napping and duration and quality of sleep in the lifestyle interventions and independence for elders pilot study
    Jennifer L Picarsic
    Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania 15213, USA
    J Am Geriatr Soc 56:1674-80. 2008
  5. ncbi request reprint Neck and shoulder pain in 70- to 79-year-old men and women: findings from the Health, Aging and Body Composition Study
    Molly T Vogt
    Department of Orthopaedic Surgery, University of Pittsburgh, Pittsburgh, PA 15213, USA
    Spine J 3:435-41. 2003
  6. ncbi request reprint Kidney function as a predictor of noncardiovascular mortality
    Linda F Fried
    VA Pittsburgh Healthcare System and Renal Electrolyte Division, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15240, USA
    J Am Soc Nephrol 16:3728-35. 2005
  7. ncbi request reprint Prevalence and risk factors for abdominal aortic aneurysms in older adults with and without isolated systolic hypertension
    B L Naydeck
    Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pennsylvania 15261, USA
    Am J Cardiol 83:759-64. 1999
  8. pmc Concurrent change in dehydroepiandrosterone sulfate and functional performance in the oldest old: results from the Cardiovascular Health Study All Stars study
    J L Sanders
    Medical Scientist Training Program, School of Medicine, University of Pittsburgh, Pennsylvania, USA
    J Gerontol A Biol Sci Med Sci 65:976-81. 2010
  9. ncbi request reprint The association of bone mineral density measures with incident cardiovascular disease in older adults
    G N Farhat
    Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA 15232, USA
    Osteoporos Int 18:999-1008. 2007
  10. pmc Poor sleep is associated with poorer physical performance and greater functional limitations in older women
    Suzanne E Goldman
    Department of Epidemiology, University ofPittsburgh, Pittsburgh, PA, USA
    Sleep 30:1317-24. 2007

Collaborators

Detail Information

Publications139 found, 100 shown here

  1. ncbi request reprint Ankle-arm index as a predictor of cardiovascular disease and mortality in the Cardiovascular Health Study. The Cardiovascular Health Study Group
    A B Newman
    University of Pittsburgh, Pittsburgh, PA, USA
    Arterioscler Thromb Vasc Biol 19:538-45. 1999
    ..1 decrement in the AAI. An AAI of <0.9 is an independent risk factor for incident CVD, recurrent CVD, and mortality in this group of older adults in the Cardiovascular Health Study...
  2. ncbi request reprint Relation of sleep-disordered breathing to cardiovascular disease risk factors: the Sleep Heart Health Study
    A B Newman
    University of Pittsburgh, 3520 Fifth Avenue, Suite 300, Pittsburgh, PA 15213, USA
    Am J Epidemiol 154:50-9. 2001
    ..If sleep-disordered breathing is shown in future follow-up to increase the risk for incident CVD events, part of the risk is likely to be due to the higher cardiovascular risk factors in those with higher RDI...
  3. ncbi request reprint Associations of subclinical cardiovascular disease with frailty
    A B Newman
    The University of Pittsburgh, Pennsylvania, USA
    J Gerontol A Biol Sci Med Sci 56:M158-66. 2001
    ..Little work has been done to define frailty and describe the underlying pathophysiology...
  4. pmc Self-reported napping and duration and quality of sleep in the lifestyle interventions and independence for elders pilot study
    Jennifer L Picarsic
    Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania 15213, USA
    J Am Geriatr Soc 56:1674-80. 2008
    ..To determine the prevalence of self-reported napping and its association with subjective nighttime sleep duration and quality, as measured according to sleep-onset latency and sleep efficiency...
  5. ncbi request reprint Neck and shoulder pain in 70- to 79-year-old men and women: findings from the Health, Aging and Body Composition Study
    Molly T Vogt
    Department of Orthopaedic Surgery, University of Pittsburgh, Pittsburgh, PA 15213, USA
    Spine J 3:435-41. 2003
    ..Musculoskeletal pain in the cervicobrachial region is considered a major health problem among adults of working age, but little is known about the impact of this pain in the elderly...
  6. ncbi request reprint Kidney function as a predictor of noncardiovascular mortality
    Linda F Fried
    VA Pittsburgh Healthcare System and Renal Electrolyte Division, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15240, USA
    J Am Soc Nephrol 16:3728-35. 2005
    ..Kidney function predicts noncardiovascular mortality from multiple causes in the elderly. Further research is needed to understand the mechanisms and evaluate interventions to reduce the high mortality rate in chronic kidney disease...
  7. ncbi request reprint Prevalence and risk factors for abdominal aortic aneurysms in older adults with and without isolated systolic hypertension
    B L Naydeck
    Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pennsylvania 15261, USA
    Am J Cardiol 83:759-64. 1999
    ..Patients with AAA also had greater wall thickness and greater diameter of the iliac arteries, which are probably associated with the underlying disease process...
  8. pmc Concurrent change in dehydroepiandrosterone sulfate and functional performance in the oldest old: results from the Cardiovascular Health Study All Stars study
    J L Sanders
    Medical Scientist Training Program, School of Medicine, University of Pittsburgh, Pennsylvania, USA
    J Gerontol A Biol Sci Med Sci 65:976-81. 2010
    ..We evaluated concurrent DHEAS and functional decline in a very old cohort to test if DHEAS change tracks with functional change during aging...
  9. ncbi request reprint The association of bone mineral density measures with incident cardiovascular disease in older adults
    G N Farhat
    Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA 15232, USA
    Osteoporos Int 18:999-1008. 2007
    ..BMD measures were inversely related to CVD in women and white men, independent of age and shared risk factors for osteoporosis and CVD...
  10. pmc Poor sleep is associated with poorer physical performance and greater functional limitations in older women
    Suzanne E Goldman
    Department of Epidemiology, University ofPittsburgh, Pittsburgh, PA, USA
    Sleep 30:1317-24. 2007
    ..This study examined the association between disturbed sleep and poorer daytime function in older women...
  11. ncbi request reprint Weight change, weight change intention, and the incidence of mobility limitation in well-functioning community-dwelling older adults
    Jung Sun Lee
    Healthy Aging Research Program, Department of Epidemiology, University of Pittsburgh, PA 15213, USA
    J Gerontol A Biol Sci Med Sci 60:1007-12. 2005
    ..The aim of this study was to determine whether weight, weight change, and weight change intention are associated with risk for mobility limitation in elderly persons...
  12. pmc Physical activity predicts gray matter volume in late adulthood: the Cardiovascular Health Study
    K I Erickson
    Department of Psychology, University of Pittsburgh, PA, USA
    Neurology 75:1415-22. 2010
    ....
  13. pmc Executive function, memory, and gait speed decline in well-functioning older adults
    N L Watson
    Department of Epidemiology, University of Pittsburgh, Pennsylvania, Pittsburgh, PA 15213 3545, USA
    J Gerontol A Biol Sci Med Sci 65:1093-100. 2010
    ..In community-dwelling older adults, global cognitive function predicts longitudinal gait speed decline. Few prospective studies have evaluated whether specific executive cognitive deficits in aging may account for gait slowing over time...
  14. ncbi request reprint The role of comorbidity in the assessment of intermittent claudication in older adults
    A B Newman
    Department of Medicine, Division of Geriatric Medicine, University of Pittsburgh School of Medicine, Keystone Blds, Suite 300, 3529 First Avenue, Pittsburgh, PA 15213 3313, USA
    J Clin Epidemiol 54:294-300. 2001
    ..The Rose Questionnaire for IC is specific for PAD, but a negative questionnaire does not indicate a lack of symptoms, rather the presence of PAD along with other conditions that can cause pain...
  15. pmc Central nervous system medication use and incident mobility limitation in community elders: the Health, Aging, and Body Composition study
    Robert M Boudreau
    Department of Epidemiology, University of Pittsburgh, PA 15213, USA
    Pharmacoepidemiol Drug Saf 18:916-22. 2009
    ..To evaluate whether CNS medication use in older adults was associated with a higher risk of future incident mobility limitation...
  16. pmc Sleep-disordered breathing in the National Football League
    Thomas B Rice
    Department of Medicine, University of Pittsburgh, Pittsburgh, PA, USA
    Sleep 33:819-24. 2010
    ..NFL players have a higher prevalence of hypertension, and we sought to determine the prevalence of SDB among players the NFL and the associations of SDB with anthropometric measures and cardiovascular risk factors...
  17. ncbi request reprint Weight change in old age and its association with mortality
    A B Newman
    Division of Geriatric Medicine, University of Pittsburgh, Pennsylvania 15213, USA
    J Am Geriatr Soc 49:1309-18. 2001
    ..CONCLUSIONS: This study confirms that even modest decline in body weight is an important and independent marker of risk of mortality in older adults...
  18. ncbi request reprint Kidney function predicts the rate of bone loss in older individuals: the Cardiovascular Health Study
    Linda F Fried
    VA Pittsburgh Healthcare System, Pittsburgh, PA 15240, USA
    J Gerontol A Biol Sci Med Sci 61:743-8. 2006
    ....
  19. ncbi request reprint The clock drawing test is an independent predictor of incident use of 24-hour care in a retirement community
    Laurie L Lavery
    Division of Geriatric Medicine, University of Pittsburgh, 3471 Fifth Ave, Suite 500, Pittsburgh, PA 15213, USA
    J Gerontol A Biol Sci Med Sci 60:928-32. 2005
    ..We examined the relationship between executive function, measured with a clock drawing protocol (CLOX1) designed to capture executive impairment, and incident need for increased level of care and total mortality...
  20. ncbi request reprint Nontraumatic fracture risk with diabetes mellitus and impaired fasting glucose in older white and black adults: the health, aging, and body composition study
    Elsa S Strotmeyer
    Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA 15213, USA
    Arch Intern Med 165:1612-7. 2005
    ..Diabetes mellitus (DM) and related complications may increase clinical fracture risk in older adults...
  21. ncbi request reprint Coronary artery calcification in older adults to age 99: prevalence and risk factors
    A B Newman
    Division of Geriatric Medicine, Department of Epidemiology, University of Pittsburgh, Pittsburgh, PA, USA
    Circulation 104:2679-84. 2001
    ..However, the prevalence and risk factors for coronary artery calcification in populations >65 years have not been well studied...
  22. ncbi request reprint Cardiovascular disease and mortality in older adults with small abdominal aortic aneurysms detected by ultrasonography: the cardiovascular health study
    A B Newman
    Division of Geriatric Medicine, University of Pittsburgh School of Medicine, 3520 Fifth Avenue, Suite 300, Pittsburgh, PA 15213, USA
    Ann Intern Med 134:182-90. 2001
    ..It is unknown whether these factors explain the high mortality rate associated with abdominal aortic aneurysm...
  23. ncbi request reprint Hormone replacement therapy is associated with higher FEV1 in elderly women
    C L Carlson
    Division of Geriatric Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania 15213, USA
    Am J Respir Crit Care Med 163:423-8. 2001
    ..67 [95% CI 0.48, 0.95]). We conclude that postmenopausal women who use HRT have higher levels of FEV1 and less obstruction, which could not be explained by their lower rates of smoking and other health factors associated with HRT use...
  24. ncbi request reprint Short-term weight changes in community-dwelling older adults: the Health, Aging, and Body Composition Weight Change Substudy
    Jung Sun Lee
    University of Pittsburgh, Pittsburgh, PA 15213, USA
    Am J Clin Nutr 82:644-50. 2005
    ..The frequency and short-term natural history of weight loss in community-dwelling older adults have not been described. Unintentional weight loss may be more likely to continue than intentional weight loss...
  25. ncbi request reprint Skeletal muscle fatigue, strength, and quality in the elderly: the Health ABC Study
    Andreas Katsiaras
    Division of Endocrinology and Metabolism, Department of Medicine, University of Pittsburgh, Pennsylvania, USA
    J Appl Physiol 99:210-6. 2005
    ..In conclusion, older men were more fatigue resistant than women, although in both men and women greater fatigue was not related to muscle weakness...
  26. ncbi request reprint Attenuation of skeletal muscle and strength in the elderly: The Health ABC Study
    B H Goodpaster
    Department of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania 15261, USA
    J Appl Physiol 90:2157-65. 2001
    ..These results demonstrate that the attenuation values of muscle on computed tomography in older persons can account for differences in muscle strength not attributed to muscle quantity...
  27. ncbi request reprint Volumetric and areal bone mineral density measures are associated with cardiovascular disease in older men and women: the health, aging, and body composition study
    G N Farhat
    Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, 130 DeSoto Street, 127 Parran Hall, PA 15261, USA
    Calcif Tissue Int 79:102-11. 2006
    ..In conclusion, our results provide further evidence for an inverse association between BMD and CVD in men and women. Future research should investigate common pathophysiological links for osteoporosis and CVD...
  28. pmc Event-related functional magnetic resonance imaging investigation of executive control in very old individuals with mild cognitive impairment
    Caterina Rosano
    School of Public Health, Department of Epidemiology, University of Pittsburgh, Pittsburgh, Pennsylvania 15213, USA
    Biol Psychiatry 57:761-7. 2005
    ....
  29. pmc 4G/5G plasminogen activator inhibitor-1 polymorphisms and haplotypes are associated with pneumonia
    Sachin Yende
    CRISMA Laboratory Clinical Research, Investigation, and Systems Modeling of Acute Illness, Department of Critical Care Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
    Am J Respir Crit Care Med 176:1129-37. 2007
    ..Whether variation within the PAI-1 gene is associated with increased susceptibility to infection is unknown...
  30. ncbi request reprint Chronic kidney disease and functional limitation in older people: health, aging and body composition study
    Linda F Fried
    Department of Veterans Affairs Pittsburgh Healthcare System, University Drive, Pittsburgh, PA 15240, USA
    J Am Geriatr Soc 54:750-6. 2006
    ..To assess whether chronic kidney disease (CKD) is independently associated with incident physical-function limitation...
  31. pmc Change in cardiovascular risk factors with progression of kidney disease
    Linda F Fried
    Renal Section, VA Pittsburgh Healthcare System, Pittsburgh, PA 15240, USA
    Am J Nephrol 29:334-41. 2009
    ..We evaluated the change in lipids, inflammatory and procoagulant biomarkers with decline in kidney function in a nested case-cohort study in the Cardiovascular Health Study, a community-based study of adults aged >65 years...
  32. ncbi request reprint Diabetes is associated independently of body composition with BMD and bone volume in older white and black men and women: The Health, Aging, and Body Composition Study
    Elsa S Strotmeyer
    Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania 15213, USA
    J Bone Miner Res 19:1084-91. 2004
    ..Diabetes predicted higher hip, whole body, and volumetric spine BMD, and lower spine bone volume, independent of body composition and fasting insulin...
  33. pmc The risk of Parkinson disease associated with urate in a community-based cohort of older adults
    S Jain
    Pittsburgh Institute for Neurodegenerative Diseases, University of Pittsburgh Graduate School of Public Health, Pittsburgh, PA 15213 3232, USA
    Neuroepidemiology 36:223-9. 2011
    ..Studies suggest an inverse association between urate concentration and the risk of Parkinson disease (PD). We investigated this in the Cardiovascular Health Study in an elderly community-based cohort of adults...
  34. pmc Genetic analysis of serum osteocalcin and bone mineral in multigenerational Afro-Caribbean families
    A L Kuipers
    Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, 130 DeSoto Street, Pittsburgh, PA 15261, USA
    Osteoporos Int 23:1521-31. 2012
    ..Osteocalcin is a major component of bone matrix. Concentrations of total, carboxylated, and uncarboxylated osteocalcin, are highly heritable and genetically correlated with bone mineral content (BMC) within African ancestry families...
  35. ncbi request reprint A new approach of measuring muscle impairment during a functional task: quadriceps muscle activity recorded during chair stand
    J S Brach
    Department of Physical Therapy, University of Pittsburgh, Pennsylvania 15260, USA
    J Gerontol A Biol Sci Med Sci 56:M767-70. 2001
    ..The purpose of this study was to describe a new approach of measuring muscle impairment during a functional task...
  36. ncbi request reprint Genetic markers for ancestry are correlated with body composition traits in older African Americans
    J R Shaffer
    Graduate School of Public Health, University of Pittsburgh, PA 15261, USA
    Osteoporos Int 18:733-41. 2007
    ..We found significant correlations between proportion of European ancestry and several musculoskeletal traits, indicating that admixture mapping may be a useful strategy for locating genes affecting these traits...
  37. pmc The burden of cardiovascular disease in the elderly: morbidity, mortality, and costs
    Ali Yazdanyar
    Center for Aging and Population Health, Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, 130 North Bellefield Avenue, Pittsburgh, PA 15213, USA
    Clin Geriatr Med 25:563-77, vii. 2009
    ..This article provides an overview of the epidemiology of CVD in older adults, including an assessment of the impact of CVD on mortality, morbidity, and health care costs...
  38. pmc Parity and cardiovascular disease risk among older women: how do pregnancy complications mediate the association?
    Janet M Catov
    University of Pittsburgh, Department of Obstetrics, Gynecology and Reproductive Sciences, Pittsburgh PA 15213, USA
    Ann Epidemiol 18:873-9. 2008
    ..To determine whether parity is associated with increased risk of cardiovascular disease (CVD) after accounting for perinatal complications...
  39. pmc Obstructive sleep apnea among obese patients with type 2 diabetes
    Gary D Foster
    Temple University, Philadelphia, Pennsylvania, USA
    Diabetes Care 32:1017-9. 2009
    ..To assess the risk factors for the presence and severity of obstructive sleep apnea (OSA) among obese patients with type 2 diabetes...
  40. pmc An overview of the design, implementation, and analyses of longitudinal studies on aging
    Anne B Newman
    Center for Aging and Population Health, Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania 15213, USA
    J Am Geriatr Soc 58:S287-91. 2010
    ..Analysis of longitudinal data requires approaches that account for inevitable missing data. New studies should take advantage of the experience obtained from longitudinal studies on aging already conducted...
  41. ncbi request reprint Volumetric BMD and vascular calcification in middle-aged women: the Study of Women's Health Across the Nation
    Ghada N Farhat
    Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, PA 15261, USA
    J Bone Miner Res 21:1839-46. 2006
    ..Lower vBMD was related to high AC, but not to CAC, independent of age and shared risk factors between osteoporosis and cardiovascular disease...
  42. ncbi request reprint Multitasking: association between poorer performance and a history of recurrent falls
    Kimberly A Faulkner
    Department of Epidemiology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
    J Am Geriatr Soc 55:570-6. 2007
    ..To examine the association between poorer performance on concurrent walking and reaction time and recurrent falls...
  43. ncbi request reprint Cardiovascular disease and risk of Alzheimer's disease
    Caterina Rosano
    Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA 15213, USA
    Neurol Res 28:612-20. 2006
    ..This review will examine the evidence for these associations and possible pathogenetic pathways. Clinical relevance and implications of these associations will also be discussed...
  44. pmc Magnetization transfer imaging, white matter hyperintensities, brain atrophy and slower gait in older men and women
    Caterina Rosano
    University of Pittsburgh, Graduate School of Public Health, Pittsburgh, PA, USA
    Neurobiol Aging 31:1197-204. 2010
    ....
  45. ncbi request reprint Coronary artery calcium and physical function in older adults: the Cardiovascular Health Study
    Marco Inzitari
    Department of Medicine, Division of Geriatric Medicine, University of Pittsburgh, 130 N Bellefield St, Room 518, Pittsburgh, PA, USA
    J Gerontol A Biol Sci Med Sci 63:1112-8. 2008
    ..However, the association between CAC and physical function is unstudied...
  46. ncbi request reprint Association between infant birth weight and maternal cardiovascular risk factors in the health, aging, and body composition study
    Janet M Catov
    Department of Epidemiology, University of Pittsburgh Graduate School of Public Health, Pittsburgh, PA 15261, USA
    Ann Epidemiol 17:36-43. 2007
    ....
  47. ncbi request reprint Geographic variations in stroke incidence and mortality among older populations in four US communities
    Aiman El-Saed
    Department of Epidemiology, University of Pittsburgh, 130 N Bellefield Ave, Rm 405, Pittsburgh, PA 15213, USA
    Stroke 37:1975-9. 2006
    ..The purpose of this study was to compare stroke incidence and mortality rates in 4 US communities...
  48. ncbi request reprint Factors associated with geographic variations in stroke incidence among older populations in four US communities
    Aiman El-Saed
    Department of Epidemiology, University of Pittsburgh, 130 N Bellefield Ave, Rm 405, Pittsburgh, PA 15213, USA
    Stroke 37:1980-5. 2006
    ..The purpose of this study was to study possible reasons for the lower stroke incidence in Allegheny County...
  49. ncbi request reprint Decreased muscle strength and quality in older adults with type 2 diabetes: the health, aging, and body composition study
    Seok Won Park
    Department of Internal Medicine, Pochon CHA University, Pochon, Korea
    Diabetes 55:1813-8. 2006
    ..In conclusion, diabetes is associated with lower skeletal muscle strength and quality. These characteristics may contribute to the development of physical disability in older adults with diabetes...
  50. pmc Special article: gait measures indicate underlying focal gray matter atrophy in the brain of older adults
    Caterina Rosano
    Department of Epidemiology, University of Pittsburgh, Pittsburgh, PA, USA
    J Gerontol A Biol Sci Med Sci 63:1380-8. 2008
    ..Our objective was to identify the spatial distribution of focal atrophy within mobility-related brain regions in relationship with quantitative gait characteristics...
  51. ncbi request reprint Inflammatory markers and incident fracture risk in older men and women: the Health Aging and Body Composition Study
    Jane A Cauley
    Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania 15261, USA
    J Bone Miner Res 22:1088-95. 2007
    ..We tested this hypothesis in relationship to fractures in 2985 men and women enrolled in the Health ABC study. Results showed that subjects with the greatest number of inflammatory markers have the highest risk of fracture...
  52. pmc Cardiovascular disease is associated with greater incident dehydroepiandrosterone sulfate decline in the oldest old: the cardiovascular health study all stars study
    Jason L Sanders
    Department of Medicine, School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA
    J Am Geriatr Soc 58:421-6. 2010
    ..To describe cross-sectional and longitudinal associations with dehydroepiandrosterone sulfate (DHEAS) and change in DHEAS with age...
  53. pmc Diabetes mellitus and gait dysfunction: possible explanatory factors
    Jennifer S Brach
    Department of Physical Therapy, School of Health and Rehabilitation Sciences, University of Pittsburgh, 6035 Forbes Tower, Pittsburgh, PA 15260, USA
    Phys Ther 88:1365-74. 2008
    ..Limited information regarding potential explanatory factors for this association exists. This study examined the association between diabetes and gait characteristics in older adults and explored potential explanatory factors...
  54. pmc Successful skeletal aging: a marker of low fracture risk and longevity. The Study of Osteoporotic Fractures (SOF)
    Jane A Cauley
    University of Pittsburgh, Department of Epidemiology, Pittsburgh, Pennsylvania 15261, USA
    J Bone Miner Res 24:134-43. 2009
    ..These women experienced a lower risk of fractures, disability, and mortality, suggesting that this phenotype may be a marker of successful aging...
  55. pmc The reliability and validity of measures of gait variability in community-dwelling older adults
    Jennifer S Brach
    Department of Physical Therapy, University of Pittsburgh, Pittsburgh, PA 15260, USA
    Arch Phys Med Rehabil 89:2293-6. 2008
    ..To examine the test-retest reliability and concurrent validity of variability of gait characteristics...
  56. doi request reprint Incident physical disability in people with lower extremity peripheral arterial disease: the role of cardiovascular disease
    Jennifer S Brach
    Department of Physical Therapy, School of Health and Rehabilitation Sciences, University of Pittsburgh, Pittsburgh, PA 15260, USA
    J Am Geriatr Soc 56:1037-44. 2008
    ..To evaluate the risk of incident physical disability and the decline in gait speed over a 6-year follow-up associated with a low ankle-arm index (AAI) in older adults...
  57. pmc Long-term function in an older cohort--the cardiovascular health study all stars study
    Anne B Newman
    Department ofEpidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania 15213, USA
    J Am Geriatr Soc 57:432-40. 2009
    ..To evaluate shared and unique risk factors for maintaining physical and cognitive function into the ninth decade and beyond...
  58. pmc Coronary artery calcium, carotid artery wall thickness, and cardiovascular disease outcomes in adults 70 to 99 years old
    Anne B Newman
    Department of Epidemiology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
    Am J Cardiol 101:186-92. 2008
    ..The CCA-IMT was more strongly related to stroke than CAC, but CAC was also a predictor of stroke...
  59. pmc Gait variability is associated with subclinical brain vascular abnormalities in high-functioning older adults
    Caterina Rosano
    Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA 15213, USA
    Neuroepidemiology 29:193-200. 2007
    ..The brain anatomical correlates of gait variability have not been studied in high-functioning community-dwelling older adults...
  60. pmc Effect of central nervous system medication use on decline in cognition in community-dwelling older adults: findings from the Health, Aging And Body Composition Study
    Rollin M Wright
    Department of Medicine, University of Pittsburgh, Pennsylvania 15213, USA
    J Am Geriatr Soc 57:243-50. 2009
    ..To evaluate whether combined use of multiple central nervous system (CNS) medications over time is associated with cognitive change...
  61. pmc Leukocyte Telomere Length Is Not Associated With BMD, Osteoporosis, or Fracture in Older Adults: Results From the Health, Aging and Body Composition Study
    Jason L Sanders
    Medical Scientist Training Program, School of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
    J Bone Miner Res 24:1531-6. 2009
    ..TL is not associated with BMD, osteoporosis, or fracture in older men or women in this sample...
  62. pmc Gait variability and the risk of incident mobility disability in community-dwelling older adults
    Jennifer S Brach
    Department of Physical Therapy, University of Pittsburgh, Division of Geriatric Medicine, Department of Epidemiology, Pittsburgh, PA 15260, USA
    J Gerontol A Biol Sci Med Sci 62:983-8. 2007
    ..Gait speed is a strong predictor of incident walking disability. The objective was to determine if gait variability adds to the prediction of incident mobility disability independent of gait speed...
  63. pmc Total and cause-specific mortality in the cardiovascular health study
    Anne B Newman
    Departments of Epidemiology and Medicine, University of Pittsburgh, 130 North Bellefield Avenue Room 532, Pittsburgh, PA 15213, USA
    J Gerontol A Biol Sci Med Sci 64:1251-61. 2009
    ..Shared risk factors could be targeted for prevention of premature death and the study of longevity...
  64. pmc Stance time and step width variability have unique contributing impairments in older persons
    Jennifer S Brach
    Department of Physical Therapy, School of Health and Rehabilitation Sciences, University of Pittsburgh, Pittsburgh, PA 15260, United States
    Gait Posture 27:431-9. 2008
    ..Specific patterns of gait variability may imply different underlying causes. Types of gait variability should be specified. Interventions may be targeted at specific types of gait variability...
  65. pmc Physical performance and subsequent disability and survival in older adults with malignancy: results from the health, aging and body composition study
    Heidi D Klepin
    Comprehensive Cancer Center, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
    J Am Geriatr Soc 58:76-82. 2010
    ..To evaluate objective physical performance measures as predictors of survival and subsequent disability in older patients with cancer...
  66. ncbi request reprint Focal atrophy and cerebrovascular disease increase dementia risk among cognitively normal older adults
    Caterina Rosano
    School of Public Health, Department of Epidemiology, University of Pittsburgh, Pennysylvania, USA
    J Neuroimaging 17:148-55. 2007
    ....
  67. ncbi request reprint Association of long-distance corridor walk performance with mortality, cardiovascular disease, mobility limitation, and disability
    Anne B Newman
    Department of Epidemiology, Physical Therapy, University of Pittsburgh, Pittsburgh, PA 15213, USA
    JAMA 295:2018-26. 2006
    ..Extended walking tests have been examined as outcome predictors in medically ill populations but not in community-dwelling older adults...
  68. ncbi request reprint Sarcopenia: alternative definitions and associations with lower extremity function
    Anne B Newman
    Division of Geriatric Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania 15213, USA
    J Am Geriatr Soc 51:1602-9. 2003
    ....
  69. ncbi request reprint Strength and muscle quality in a well-functioning cohort of older adults: the Health, Aging and Body Composition Study
    Anne B Newman
    Department of Medicine, Division of Geriatric Medicine, University of Pittsburgh School of Medicine, 3520 5th Avenue, Suite 300, Pittsburgh, PA 15213, USA
    J Am Geriatr Soc 51:323-30. 2003
    ..To determine whether lower lean mass and higher fat mass have independent effects on the loss of strength and muscle quality in older adults and might explain part of the effect of age...
  70. ncbi request reprint Weight-loss intention in the well-functioning, community-dwelling elderly: associations with diet quality, physical activity, and weight change
    Jung Sun Lee
    Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, 130 North Bellefield Avenue, 5th Floor, Pittsburgh, PA 15213, USA
    Am J Clin Nutr 80:466-74. 2004
    ..Many older adults desire to lose weight, yet the proportion with a health-related weight-loss indication, weight-loss strategies, and success is unknown...
  71. ncbi request reprint Walking performance and cardiovascular response: associations with age and morbidity--the Health, Aging and Body Composition Study
    Anne B Newman
    Division of Geriatric Medicine, Department of Medicine, University of Pittsburgh, Pennsylvania 15213, USA
    J Gerontol A Biol Sci Med Sci 58:715-20. 2003
    ..The long-distance corridor walk is a timed 400-meter walk test used to assess walking endurance in well-functioning men and women aged 70-79 in the Health, Aging and Body Composition Study...
  72. ncbi request reprint Dementia and Alzheimer's disease incidence in relationship to cardiovascular disease in the Cardiovascular Health Study cohort
    Anne B Newman
    Department of Epidemiology, University of Pittsburgh, Pittsburgh, Pennsylvania 15213, USA
    J Am Geriatr Soc 53:1101-7. 2005
    ..To determine whether coronary artery disease, peripheral arterial disease (PAD), or noninvasive markers of cardiovascular disease (CVD) predict the onset of dementia and Alzheimer's disease (AD)...
  73. ncbi request reprint Physical activity and functional status in community-dwelling older women: a 14-year prospective study
    Jennifer S Brach
    Department of Physical Therapy, School of Health and Rehabilitation Sciences, University of Pittsburgh, 6035 Forbes Tower, Pittsburgh, PA 15260, USA
    Arch Intern Med 163:2565-71. 2003
    ..Short-term prospective studies have shown physical activity to be related to functional status. To our knowledge, the association between physical activity levels and functional status over a longer period has not been established...
  74. ncbi request reprint The association between physical function and lifestyle activity and exercise in the health, aging and body composition study
    Jennifer S Brach
    Department of Physical Therapy, School of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvannia 15260, USA
    J Am Geriatr Soc 52:502-9. 2004
    ..To determine whether older adults who exercise demonstrate higher levels of physical function than those who do not exercise but are physically active throughout the day...
  75. ncbi request reprint Reciprocal influence of concurrent walking and cognitive testing on performance in older adults
    Kimberly A Faulkner
    University of Pittsburgh, 130 DeSoto Street, Parran 509, Pittsburgh, PA 15261, USA
    Gait Posture 24:182-9. 2006
    ..062). Findings suggest that walking requires significant cognitive resources among older adults and slower-walking adults and weaker adults may require higher cognitive loading while walking...
  76. ncbi request reprint Systemic inflammatory markers, periodontal diseases, and periodontal infections in an elderly population
    Walter A Bretz
    Division of Pediatric and Developmental Science, University of Pittsburgh, PA 15261, USA
    J Am Geriatr Soc 53:1532-7. 2005
    ..To study the levels of systemic markers for inflammation with parameters of periodontal diseases in older people...
  77. ncbi request reprint Relationship between coronary artery calcification and other measures of subclinical cardiovascular disease in older adults
    Anne B Newman
    Division of Geriatric Medicine, University of Pittsburgh, PA 15213, USA
    Arterioscler Thromb Vasc Biol 22:1674-9. 2002
    ..In the Cardiovascular Health Study, subclinical cardiovascular disease (CVD) predicted CVD events in older adults. The extent to which this measure or its components reflect calcified coronary disease is unknown...
  78. ncbi request reprint Coronary artery calcium: associations with brain magnetic resonance imaging abnormalities and cognitive status
    Caterina Rosano
    Department of Epidemiology, School of Public Health, University of Pittsburgh, 130 N Bellefield Avenue, Pittsburgh, PA 15260, USA
    J Am Geriatr Soc 53:609-15. 2005
    ..To evaluate the association between coronary atherosclerosis and subclinical brain magnetic resonance imaging (MRI) abnormalities and between coronary atherosclerosis and abnormal cognitive function (dementia/mild cognitive impairment)...
  79. ncbi request reprint Influence of marital status on physical activity levels among older adults
    Kelley K Pettee
    University of Pittsburgh, Pittsburgh, PA, USA
    Med Sci Sports Exerc 38:541-6. 2006
    ....
  80. ncbi request reprint Hearing sensitivity and bone mineral density in older adults: the Health, Aging and Body Composition Study
    Elizabeth P Helzner
    Department of Epidemiology, University of Pittsburgh, Pittsburgh, PA, USA
    Osteoporos Int 16:1675-82. 2005
    ..These results suggest that axial and appendicular bone parameters may be modestly associated with hearing loss in older men, but not in women...
  81. ncbi request reprint Race and sex differences in age-related hearing loss: the Health, Aging and Body Composition Study
    Elizabeth P Helzner
    Department of Epidemiology, University of Pittsburgh, Pittsburgh, Pennsylvania 15261, USA
    J Am Geriatr Soc 53:2119-27. 2005
    ..To determine the prevalence of and risk factors for hearing loss in a sample of 2,052 older adults (aged 73-84; 46.9% male, 37.3% black) enrolled in the Health, Aging and Body Composition (Health ABC) Study...
  82. pmc The association of osteoarthritis risk factors with localized, regional and diffuse knee pain
    L R Thompson
    Department of Medicine, University of Pittsburgh, School of Medicine, Pittsburgh, PA, United States
    Osteoarthritis Cartilage 18:1244-9. 2010
    ..To identify determinants of different patterns of knee pain with a focus on risk factors for knee osteoarthritis (OA)...
  83. ncbi request reprint Preclinical Alzheimer disease: neuropsychological test performance 1.5 to 8 years prior to onset
    J Saxton
    University of Pittsburgh, Oxford Building, Room 738, Pittsburgh, PA 15213, USA
    Neurology 63:2341-7. 2004
    ..To determine if individuals ultimately diagnosed with Alzheimer disease (AD) exhibited evidence of cognitive impairment on neuropsychological tests administered between 1.5 years and 8.1 years before dementia onset...
  84. ncbi request reprint Gait variability in community-dwelling older adults
    J S Brach
    Department of Physical Therapy, School of Health and Rehabilitation Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania 15260, USA
    J Am Geriatr Soc 49:1646-50. 2001
    ..Improvement in step-length and step-width variability with attempted acceleration might be a key factor to examine in future studies of disability risk and therapeutic interventions...
  85. ncbi request reprint Functional neuroimaging indicators of successful executive control in the oldest old
    C Rosano
    School of Public Health, Department of Epidemiology, University of Pittsburgh, PA 15260, USA
    Neuroimage 28:881-9. 2005
    ..Older adults who are able to perform executive control tasks as well as young adults, also seem to implement speed-accuracy trade-off strategies which may rely on increased parietal activation...
  86. ncbi request reprint Higher 1,25-dihydroxyvitamin D3 concentrations associated with lower fall rates in older community-dwelling women
    K A Faulkner
    University of Pittsburgh, 130 DeSoto Street, Parran 509, Pittsburgh, PA 15261, USA
    Osteoporos Int 17:1318-28. 2006
    ..The purpose of this study was to examine the relationships of vitamin D supplementation and serum concentrations of vitamin D metabolites and parathyroid hormone (PTH) with neuromuscular function and falls in older community-dwelling women...
  87. pmc Inflammatory markers are associated with ventilatory limitation and muscle dysfunction in obstructive lung disease in well functioning elderly subjects
    S Yende
    CRISMA Laboratory Clinical Research, Investigation, and Systems Modeling of Acute Illness, Department of Critical Care Medicine, University of Pittsburgh, PA 15238, USA
    Thorax 61:10-6. 2006
    ..Inflammatory markers are increased in chronic obstructive pulmonary disease (COPD) and are hypothesised to play an important part in muscle dysfunction and exercise intolerance...
  88. ncbi request reprint Predicting the development of diabetes in older adults: the derivation and validation of a prediction rule
    Alka M Kanaya
    Department of Medicine and Epidemiology and Biostatics, University of California, San Francisco, California 94115, USA
    Diabetes Care 28:404-8. 2005
    ..We created a prediction rule in one sample and prospectively validated it for incident diabetes in a separate cohort...
  89. ncbi request reprint Physical activity in prefrail older adults: confidence and satisfaction related to physical function
    W Jack Rejeski
    Department of Health and Exercise Science, Box 7868, Wake Forest University, Winston Salem, NC 27109, USA
    J Gerontol B Psychol Sci Soc Sci 63:P19-26. 2008
    ..This is an important finding in light of the importance of these process variables in behavior change and quality of life...
  90. ncbi request reprint The association between lipid levels and the risks of incident myocardial infarction, stroke, and total mortality: The Cardiovascular Health Study
    Bruce M Psaty
    Cardiovascular Health Research Unit, Departments of Medicine, Epidemiology and Health Services, University of Washington, Seattle, Washington 98101, USA
    J Am Geriatr Soc 52:1639-47. 2004
    ..To assess the association between lipid levels and cardiovascular events in older adults...
  91. ncbi request reprint Association of visceral adipose tissue with incident myocardial infarction in older men and women: the Health, Aging and Body Composition Study
    Barbara J Nicklas
    Section on Gerontology and Geriatric Medicine, Sticht Center on Aging, Wake Forest University School of Medicine, Winston Salem, NC, USA
    Am J Epidemiol 160:741-9. 2004
    ..79, 95% confidence interval: 1.24, 2.58 per standard-deviation increase; p < 0.01). The amount of adipose tissue stored in the intraabdominal cavity is an important, independent risk factor for MI in well-functioning, elderly women...
  92. pmc Association between nighttime sleep and napping in older adults
    Suzanne E Goldman
    Department of Neurology, Sleep Disorders Program, Vanderbilt University Medical Center, Nashville, TN 37232, USA
    Sleep 31:733-40. 2008
    ..Napping might indicate deficiencies in nighttime sleep, but the relationship is not well defined. We assessed the association of nighttime sleep duration and fragmentation with subsequent daytime sleep...
  93. pmc Black and white differences in cognitive function test scores: what explains the difference?
    Kala M Mehta
    Division of Geriatrics, University of California at San Francisco, 94121, USA
    J Am Geriatr Soc 52:2120-7. 2004
    ..This study evaluates whether differences in health and socioeconomic indicators, including literacy level, can explain differences in cognitive function test scores between older black and white adults...
  94. pmc Fetuin-A and incident diabetes mellitus in older persons
    Joachim H Ix
    Division of Nephrology and Hypertension, Department of Medicine, University of California, San Diego, and San Diego Veterans Affairs Healthcare System, 3350 La Jolla Village Dr, Mail Code 111 H, San Diego, CA 92161, USA
    JAMA 300:182-8. 2008
    ..In prior cross-sectional studies in humans, higher fetuin-A levels were associated with insulin resistance. However, the longitudinal association of fetuin-A with incident type 2 diabetes mellitus is unknown...
  95. ncbi request reprint Inflammatory markers and incident mobility limitation in the elderly
    Brenda W J H Penninx
    Sticht Center on Aging, Section on Gerontology and Geriatric Medicine, Wake Forest University School of Medicine, Winston Salem, North Carolina, USA
    J Am Geriatr Soc 52:1105-13. 2004
    ..To examine the relationship between indicators of inflammation and the incidence of mobility limitation in older persons...
  96. ncbi request reprint Predictors of sleep-disordered breathing in community-dwelling adults: the Sleep Heart Health Study
    Terry Young
    Department of Population Health Sciences, University of Wisconsin, Madison, WI, USA
    Arch Intern Med 162:893-900. 2002
    ..Information on demographic patterns of SDB occurrence and its predictive factors in the general population is needed to target high-risk groups that may benefit from diagnosis...
  97. ncbi request reprint Relationship of interleukin-6 and tumor necrosis factor-alpha with muscle mass and muscle strength in elderly men and women: the Health ABC Study
    Marjolein Visser
    Institute for Research in Extramural Medicine, VU University Medical Center, Amsterdam, The Netherlands
    J Gerontol A Biol Sci Med Sci 57:M326-32. 2002
    ....
  98. ncbi request reprint Leg muscle mass and composition in relation to lower extremity performance in men and women aged 70 to 79: the health, aging and body composition study
    Marjolein Visser
    Institute for Research in Extramural Medicine, Faculty of Medicine, Vrije Universiteit, Amsterdam, The Netherlands
    J Am Geriatr Soc 50:897-904. 2002
    ..Our aim was to determine whether low leg muscle mass and greater fat infiltration in the muscle were associated with poor lower extremity performance (LEP)...
  99. ncbi request reprint The 6-min walk test: a quick measure of functional status in elderly adults
    Paul L Enright
    University of Arizona, USA
    Chest 123:387-98. 2003
    ..To determine the correlates of the total 6-min walk distance (6MWD) in a population sample of adults > or = 68 years old...
  100. ncbi request reprint One- and two-year change in body composition as measured by DXA in a population-based cohort of older men and women
    Marjolein Visser
    Institute for Research in Extramural Medicine, Vrije University Medical Center, 1081 BT Amsterdam, The Netherlands
    J Appl Physiol 94:2368-74. 2003
    ..Loss of ALST was greater in men compared with women, and greater in blacks compared with whites, suggesting that men and blacks may be more prone to muscle loss...
  101. ncbi request reprint Association of high coronary heart disease risk status with circulating oxidized LDL in the well-functioning elderly: findings from the Health, Aging, and Body Composition study
    Paul Holvoet
    Center for Experimental Surgery and Anesthesiology, Katholieke Universiteit, Leuven, Belgium
    Arterioscler Thromb Vasc Biol 23:1444-8. 2003
    ..Therefore, we studied the association between high, predicted CHD risk and oxLDL in the Health ABC cohort...