Research Topics
| A NewbergSummaryAffiliation: University of Pennsylvania Country: USA Publications
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Detail Information
Publications
The measurement of regional cerebral blood flow during the complex cognitive task of meditation: a preliminary SPECT studyA Newberg
Division of Nuclear Medicine, Department of Radiology, University of Pennsylvania Medical Center, Philadelphia, PA 19104, USA
Psychiatry Res 106:113-22. 2001..The correlation between the DLPFC and the superior parietal lobe may reflect an altered sense of space experienced during meditation. These results suggest a complex rCBF pattern during the task of meditation...
Cerebral blood flow during meditative prayer: preliminary findings and methodological issuesAndrew Newberg
Division of Nuclear Medicine, Hospital of the University of Pennsylvania, Philadelphia 19104, USA
Percept Mot Skills 97:625-30. 2003....
Cerebral metabolic changes associated with Lyme diseaseA Newberg
Division of Nuclear Medicine, Hospital of the University of Pennsylvania, 110 Donner Building, 3400 Spruce Street, Philadelphia, PA 19104, USA
Nucl Med Commun 23:773-7. 2002....
[99mTc]TRODAT-1 SPECT imaging correlates with odor identification in early Parkinson diseaseA Siderowf
Parkinson Disease and Movement Disorders Center, Department of Neurology, University of Pennsylvania, Philadelphia, USA
Neurology 64:1716-20. 2005..In vivo imaging of the dopamine transporter with [99mTc]TRODAT-1 (TRODAT) and olfactory testing have both been proposed as potential biomarkers in Parkinson disease (PD)...
F-18 FDG uptake in the large arteries: a new observationM Yun
Department of Nuclear Medicine, Hospital of the University of Pennsylvania, Philadelphia 19104, USA
Clin Nucl Med 26:314-9. 2001..The relative contribution of these sources needs further investigation...
Brain metabolism in the cerebellum and visual cortex correlates with neuropsychological testing in patients with Alzheimer's diseaseA Newberg
Department of Radiology and Neurology, Hospital of the University of Pennsylvania, Philadelphia, PA 19104, USA
Nucl Med Commun 24:785-90. 2003..This may have important clinical and pathophysiological implications in the study of AD and other illnesses of dementia...
Biomarkers for early detection of Alzheimer pathologyC M Clark
Department of Neurology, University of Pennsylvania, Philadelphia, PA 19104, USA
Neurosignals 16:11-8. 2008..Success will facilitate the ability to reliably diagnose Alzheimer's disease while the symptoms of brain failure are mild and may provide objective measures of disease-modifying treatment efficacy...
Diagnostic accuracy of [99mTc]TRODAT-1 SPECT imaging in early Parkinson's diseaseK L Chou
Parkinson s Disease and Movement Disorders Center, University of Pennsylvania School of Medicine, Pennsylvania Hospital, 330 South Ninth Street, Philadelphia, PA 19107, USA
Parkinsonism Relat Disord 10:375-9. 2004..79, specificity 0.92). These findings show that TRODAT imaging can accurately differentiate early PD patients from controls and has the potential to improve the diagnosis of patients with early signs of PD...
Dopamine transporter binding in smokers and nonsmokersAndrew Newberg
Division of Nuclear Medicine, Department of Radiology, University of Pennsylvania Health System, Philadelphia, PA, USA
Clin Nucl Med 32:452-5. 2007..This study determined whether healthy current smokers and nonsmokers exhibit differences in dopamine transporter (DAT) binding measured by Tc-99m TRODAT SPECT...
Deep venous thrombosis on F-18 FDG PET/CT imagingBrian D Sydow
Division of Nuclear Medicine, Department of Radiology, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
Clin Nucl Med 31:403-4. 2006
Artificial neural network classifier for the diagnosis of Parkinson's disease using [99mTc]TRODAT-1 and SPECTPaul D Acton
Department of Radiology, Thomas Jefferson University, Philadelphia, PA 19107, USA
Phys Med Biol 51:3057-66. 2006..4% total accuracy, 97.5% specificity and 91.4% sensitivity). However, it should be stressed that, as with all applications of an ANN, it was difficult to interpret precisely what triggers in the images were being detected by the network...
Comparison of region-of-interest analysis and human observers in the diagnosis of Parkinson's disease using [99mTc]TRODAT-1 and SPECTPaul D Acton
Department of Radiology, Thomas Jefferson University, Philadelphia, PA 19107, USA
Phys Med Biol 51:575-85. 2006..89, best ROI AUC = 0.90). This suggested that the human observers are visually acquiring similar information from the images that are contained in the semi-quantitative striatal uptake...
Dopamine transporter density may be associated with the depressed affect in healthy subjectsAndrew Newberg
Department of Radiology, Division of Nuclear Medicine, University of Pennsylvania, 3400 Spruce Street, Philadelphia, PA 19104, USA
Nucl Med Commun 28:3-6. 2007..We used the selective DAT radiopharmaceutical Tc-TRODAT-1 and SPECT brain imaging, to examine differences in DAT levels in healthy subjects with and without depressive affect...
Pilot study on the effect of estrogen replacement therapy on brain dopamine transporter availability in healthy, postmenopausal womenSara A Gardiner
ePharmaLearning, Inc
Am J Geriatr Psychiatry 12:621-30. 2004..Authors investigated the association between estrogen replacement therapy (ERT) and dopamine transporter (DAT) availability in women...
Greater availability of brain dopamine transporters in major depression shown by [99m Tc]TRODAT-1 SPECT imagingDavid J Brunswick
Depression Research Unit, Department of Radiology, University of Pennsylvania Medical Center, Philadelphia, PA 19104, USA
Am J Psychiatry 160:1836-41. 2003..The present study was an examination of the availability of brain dopamine transporter sites in patients with major depression and in healthy comparison subjects...
A metabolic imaging severity rating scale for the assessment of cognitive impairmentAndrew Newberg
Division of Nuclear Medicine, Department of Radiology, Hospital of the University of Pennsylvania, Philadelphia, 19104, USA
Clin Nucl Med 28:565-70. 2003..This study was designed to validate a simple scoring system for evaluating fluorodeoxyglucose (FDG) positron emission tomographic (PET) scans that can be used routinely in patients undergoing the clinical assessment of cognitive impairment...
FDG-PET imaging can diagnose periprosthetic infection of the hipTimothy Chryssikos
Department of Nuclear Medicine, University of Pennsylvania, Philadelphia, PA, USA
Clin Orthop Relat Res 466:1338-42. 2008..LEVEL OF EVIDENCE: Level II, diagnostic study. See Guidelines for Authors for a complete description of levels of evidence...
Neuroimaging in traumatic brain imagingBruce Lee
Department of Medicine, University of Pennsylvania Health System, Philadelphia, Pennsylvani 19104, USA
NeuroRx 2:372-83. 2005..Neuroimaging also can be important in the chronic therapy of TBI, identifying chronic sequelae, determining prognosis, and guiding rehabilitation...
Clinical validation of fully 3-D versus 2.5-D RAMLA reconstruction on the Philips-ADAC CPET PET scannerStephen Chiang
Department of Radiology, University of Pennsylvania, USA
Nucl Med Commun 25:1103-7. 2004..CONCLUSION: This study led to the routine use of 3-D RAMLA reconstruction on the CPET scanner at our institution...
Radiologic diagnosis of brain deathAndrew Newberg
JAMA 288:2121-2. 2002
Determination of regional cerebral function with FDG-PET imaging in neuropsychiatric disordersAndrew Newberg
Division of Nuclear Medicine, The Hospital of the University of Pennsylvania, Philadelphia 19104, USA
Semin Nucl Med 32:13-34. 2002..This article will also explore what FDG-PET imaging has revealed in these neuropsychiatric disorders and how these findings relate to both research and clinical applications...
