Research Topics
| K M NeuzilSummaryAffiliation: University of Washington Country: USA Publications
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Publications
The effect of influenza on hospitalizations, outpatient visits, and courses of antibiotics in childrenK M Neuzil
Department of Medicine, University of Washington School of Medicine, Seattle, USA
N Engl J Med 342:225-31. 2000..We measured the disease burden of influenza in a large cohort of healthy children in the Tennessee Medicaid program who were younger than 15 years of age...
Cardiopulmonary hospitalizations during influenza season in adults and adolescents with advanced HIV infectionKathleen M Neuzil
Department of Medicine, University of Washington and the Veterans Affairs Puget Sound Health Care System, Seattle, WA, USA
J Acquir Immune Defic Syndr 34:304-7. 2003..Influenza-associated hospitalizations have declined in patients with HIV infection in the post-HAART era. Rates remain comparable to rates in other high-risk groups for which annual influenza vaccination is recommended, however...
Recognizing influenza in older patients with chronic obstructive pulmonary disease who have received influenza vaccineKathleen M Neuzil
Department of Veterans Affairs Puget Sound Health Care System and University of Washington School of Medicine, Seattle, Washington 98108, USA
Clin Infect Dis 36:169-74. 2003..Additional studies are warranted to define optimal methods for the diagnosis of influenza among older persons with chronic obstructive pulmonary disease...
Illness among schoolchildren during influenza season: effect on school absenteeism, parental absenteeism from work, and secondary illness in familiesKathleen M Neuzil
University of Washington School of Medicine, Veterans Affairs Puget Sound Health Care System, 1660 S Columbian Way, Seattle, WA 98108, USA
Arch Pediatr Adolesc Med 156:986-91. 2002..High attack rates of Influenzavirus among school-aged children tend to be expected to cause significant disruption of usual activities at school and at home...
Burden of interpandemic influenza in children younger than 5 years: a 25-year prospective studyKathleen M Neuzil
Division of Infectious Diseases, Department of Medicine, University of Washington School of Medicine, Seattle, Washington, USA
J Infect Dis 185:147-52. 2002..Hospitalizations associated with culture-positive influenza occurred at an annual rate of 3-4 per 1000 children aged <2 years. Influenza is associated with substantial morbidity in otherwise healthy children aged <5 years...
Winter respiratory viruses and health care use: a population-based study in the northwest United StatesKathleen M Neuzil
Department of Medicine, University of Washington School of Medicine, Seattle, USA
Clin Infect Dis 37:201-7. 2003..1-1.5) per 1000 low-risk individuals aged 18-49 years, to 10.6 (95% CI, 7.5-13.6) per 1000 high-risk individuals aged >or=65 years. Each year, circulation of influenza and RSV coincide with predictable increases in medical care use...
Effectiveness of pneumococcal polysaccharide vaccine in older adultsLisa A Jackson
Center for Health Studies, Group Health Cooperative, Seattle, WA 98101, USA
N Engl J Med 348:1747-55. 2003..In a large population of older adults, we assessed the effectiveness of the pneumococcal vaccine...
Immunogenicity and reactogenicity of 1 versus 2 doses of trivalent inactivated influenza vaccine in vaccine-naive 5-8-year-old childrenKathleen M Neuzil
Program for Appropriate Technology in Health, School of Medicine, University of Washington, Seattle, Seattle, WA 98107, USA
J Infect Dis 194:1032-9. 2006..This study assessed the need for a second dose of TIV in this age group...
Efficacy of inactivated and cold-adapted vaccines against influenza A infection, 1985 to 1990: the pediatric experienceK M Neuzil
Department of Medicine, University of Washington School of Medicine, Seattle, WA 98108, USA
Pediatr Infect Dis J 20:733-40. 2001..Although there is interest in broadening the use of influenza vaccine in healthy children, there are few large, randomized, controlled trials that evaluate the safety and efficacy of inactivated vaccine in the pediatric population...
Characteristics and outcomes of older adults with community-acquired pneumococcal bacteremiaRu Chien Chi
Division of Gerontology and Geriatric Medicine, Department of Medicine, School of Medicine, University of Washington, Seattle, Washington, USA
J Am Geriatr Soc 54:115-20. 2006..To describe baseline characteristics and clinical outcomes of older adults with pneumococcal bacteremia, compare the frequency of serious outcomes according to pneumococcal vaccination status, and assess factors associated with mortality...
The association of sociodemographic factors and patient attitudes on influenza vaccination rates in older personsRu Chien Chi
Department of Medicine, School of Medicine, University of Washington and the VA Puget Sound Health Care System, Seattle, Washington, USA
Am J Med Sci 327:113-7. 2004..To determine how patient attitudes, beliefs, knowledge, and sociodemographic characteristics relate to influenza vaccine acceptance in an older patient population...
Influenza and pneumococcal vaccination in older veterans: results from the behavioral risk factor surveillance systemRu Chien Chi
Division of Gerontology and Geriatric Medicine, Department of Medicine, School of Medicine, University of Washington, Seattle, Washington, USA
J Am Geriatr Soc 54:217-23. 2006..S. Department of Veterans Affairs (VA) medical centers with those of veterans who do not...
Predictors of influenza vaccination in the Cystic Fibrosis Foundation patient registry, 2006 through 2007Justin R Ortiz
Division of Pulmonary and Critical Care Medicine, University of Washington Medical Center, Seattle, WA 98195 6522, USA
Chest 138:1448-55. 2010..Influenza vaccination is recommended for all persons with cystic fibrosis (CF). Despite this recommendation, no study has been performed to determine factors associated with receipt of influenza vaccination among persons with CF...
Influenza-associated cystic fibrosis pulmonary exacerbationsJustin R Ortiz
Division of Pulmonary and Critical Care Medicine, University of Washington Medical Center, Box 356522, 1959 NE Pacific St, Seattle, WA 98195 6522, USA
Chest 137:852-60. 2010..Although cystic fibrosis (CF) is the most common inherited respiratory disease, the burden of influenza among individuals with CF is not well characterized...
Influenza vaccination rates of children in households with high-risk adultsRu Chien Chi
Veterans Administration Puget Sound Health Care System, Seattle, WA, USA
Public Health Rep 125:192-8. 2010..We evaluated influenza vaccine coverage among children to determine whether or not living with a high-risk adult predicts the likelihood of being vaccinated...
Immunogenicity and safety of intradermal influenza vaccination in healthy older adultsRu Chien Chi
University of Washington, Seattle, Washington, USA
Clin Infect Dis 50:1331-8. 2010..Influenza vaccine immunogenicity is suboptimal in older persons. Intradermal (ID) vaccination may be a promising alternative to intramuscular (IM) vaccination...
Evidence of bias in estimates of influenza vaccine effectiveness in seniorsLisa A Jackson
Center for Health Studies, Group Health Cooperative, Seattle, WA 98101, USA
Int J Epidemiol 35:337-44. 2006..Since a protective effect of vaccination should be specific to influenza season, evaluation of non-influenza periods could indicate the possible contribution of bias to the estimates observed during influenza season...
Burden of community-onset Escherichia coli bacteremia in seniorsLisa A Jackson
Center for Health Studies, Group Health Cooperative, and Department of Epidemiology, University of Washington, Seattle, Washington 98101, USA
J Infect Dis 191:1523-9. 2005..Although Escherichia coli is a well-recognized cause of urinary tract infection in seniors, little is known about the burden of invasive E. coli infection in this population...
Influenza vaccine: issues and opportunitiesK M Neuzil
Division of Infectious Diseases, University of Washington School of Medicine, Seattle, USA
Infect Dis Clin North Am 15:123-41, ix. 2001..This includes pregnant women who are in their second or third trimesters during influenza season...
Immunization with trivalent inactivated influenza vaccine in partially immunized toddlersJanet A Englund
Pediatric ID, Children s Hospital and Regional Medical Center, 4800 Sand Point Way, NE W8851, Seattle, Washington 98105, USA
Pediatrics 118:e579-85. 2006....
Functional status is a confounder of the association of influenza vaccine and risk of all cause mortality in seniorsLisa A Jackson
Center for Health Studies, Group Health Cooperative, Seattle, WA 98101, USA
Int J Epidemiol 35:345-52. 2006....
Influenza vaccination and risk of community-acquired pneumonia in immunocompetent elderly people: a population-based, nested case-control studyMichael L Jackson
Group Health Center for Health Studies, Seattle, WA 98101 1448, USA
Lancet 372:398-405. 2008..We therefore assessed whether influenza vaccination is associated with a reduced risk of community-acquired pneumonia in immunocompetent elderly people after controlling for health status indicators...
Influenza vaccines in childrenKathleen M Neuzil
Division of Allergy and Infectious Diseases, University of Washington School of Medicine, Seattle, USA
Semin Pediatr Infect Dis 13:174-81. 2002....
A comparison of 2 influenza vaccine schedules in 6- to 23-month-old childrenJanet A Englund
Division of Pediatric Infectious Diseases, Allergy, and Rheumatology, University of Washington and Children s Hospital and Regional Medical Center, Seattle, Washington 98105, USA
Pediatrics 115:1039-47. 2005..Trivalent inactivated influenza vaccine (TIV) is recommended for all children ages 6 to 23 months. Delivering 2 doses of TIV at least 4 weeks apart to young children receiving this vaccine for the first time is challenging...
Maternal morbidity and perinatal outcomes among pregnant women with respiratory hospitalizations during influenza seasonTina V Hartert
Department of Medicine, Division of General Internal Medicine, Vanderbilt University School of Medicine, Nashville, TN 37232 2650, USA
Am J Obstet Gynecol 189:1705-12. 2003..The objectives of this investigation were to describe and quantify the impact of respiratory hospitalization during pregnancy on serious maternal and perinatal morbidity...
Comparison of the safety and immunogenicity of 2 respiratory syncytial virus (rsv) vaccines--nonadjuvanted vaccine or vaccine adjuvanted with alum--given concomitantly with influenza vaccine to high-risk elderly individualsAnn R Falsey
Department of Medicine, Rochester General Hospital, and University of Rochester School of Medicine, Rochester, NY 14621, USA
J Infect Dis 198:1317-26. 2008..Respiratory syncytial virus (RSV) has been recognized recently as an important adult pathogen...
The burden of community-acquired pneumonia in seniors: results of a population-based studyMichael L Jackson
Center for Health Studies, Group Health Cooperative, University of Washington, Seattle, USA
Clin Infect Dis 39:1642-50. 2004....
Compliance with the recommendations for 2 doses of trivalent inactivated influenza vaccine in children less than 9 years of age receiving influenza vaccine for the first time: a Vaccine Safety Datalink studyLisa A Jackson
Group Health Center for Health Studies, Seattle, Washington, USA
Pediatrics 118:2032-7. 2006..We conducted a population-based retrospective cohort study to evaluate compliance with the 2-dose trivalent inactivated influenza vaccine recommendations...
Safety of varying dosages of 7-valent pneumococcal protein conjugate vaccine in seniors previously vaccinated with 23-valent pneumococcal polysaccharide vaccineLisa A Jackson
Center for Health Studies, Group Health Cooperative, 1730 Minor Ave, Ste 1600, Seattle, WA 98101, USA
Vaccine 23:3697-703. 2005..Fever was uncommon and did not vary by study group. The rate of local reactions increased with higher volumes of PCV and the rate following 2.0 ml of PCV was comparable to that following 0.5 ml PPV...
Immunogenicity of varying dosages of 7-valent pneumococcal polysaccharide-protein conjugate vaccine in seniors previously vaccinated with 23-valent pneumococcal polysaccharide vaccineLisa A Jackson
Group Health Center for Health Studies, 1730 Minor Ave, Ste 1600, Seattle, WA 98101, USA
Vaccine 25:4029-37. 2007..A booster response to the challenge vaccination was not observed. Administration of a 1 ml dose of PnC vaccine is more immunogenic than 0.5 ml of PnPS vaccine in elderly adults previously vaccinated with PnPS vaccine...
Assessment of the safety of a third dose of pneumococcal polysaccharide vaccine in the Vaccine Safety Datalink populationLisa A Jackson
Center for Health Studies, 1730 Minor Ave, Ste 1600, Seattle, WA 98101, USA
Vaccine 24:151-6. 2006..5 for both comparisons with the third PPV group). These findings do not suggest that a third PPV dose is associated with an increased risk of medically attended injection site reactions compared with a first or second PPV dose...
Impact of a winter respiratory virus season on patients with COPD and association with influenza vaccinationGeoffrey J Gorse
Division of Infectious Diseases and Immunology, Saint Louis University Health Sciences Center, 3635 Vista Ave FDT 8N, St Louis, MO 63110, USA
Chest 130:1109-16. 2006....
An economic analysis of annual influenza vaccination of childrenMartin I Meltzer
Mailstop D 59, OS OD NCID CDC, 1600 Clifton Road, Atlanta, GA 30333, USA
Vaccine 23:1004-14. 2005..The probability of death, though rare, was the most influential distribution in the model. The number of high-risk children that receive influenza vaccine should be maximized to achieve improved health outcomes as well as cost savings...
Winter viruses: influenza- and respiratory syncytial virus-related morbidity in chronic lung diseaseMarie R Griffin
Vanderbilt University School of Medicine, Department of Preventive Medicine, A 1124 MCN, Nashville, TN 37232, USA
Arch Intern Med 162:1229-36. 2002..While respiratory syncytial virus (RSV) is recognized as an important target of vaccine development for infants, its impact on adults is underappreciated...
The global implications of influenza in Hong KongMarie R Griffin
N Engl J Med 347:2159-62. 2002
Influenza vaccine immunogenicity in 6- to 23-month-old children: are identical antigens necessary for priming?Emmanuel B Walter
Duke Clinical Research Institute, Department of Pediatrics, Duke University Medical Center, Durham, North Carolina, USA
Pediatrics 118:e570-8. 2006....
Efficacy trial of live, cold-adapted and inactivated influenza virus vaccines in older adults with chronic obstructive pulmonary disease: a VA cooperative studyGeoffrey J Gorse
Department of Veterans Affairs, Medical Center, Saint Louis University, St Louis, MO, USA
Vaccine 21:2133-44. 2003..17, 0.53), and -0.05 for type B virus (95% CL: -1.13, 0.48). However, there was a possible advantage for TC over TP in reducing respiratory consequences of an influenza season measured by pulmonary function and symptoms at end of study...
Vaccine safety--achieving the proper balanceKathleen M Neuzil
JAMA 294:2763-5. 2005
Prevention of herpes zoster: recommendations of the Advisory Committee on Immunization Practices (ACIP)Rafael Harpaz
Division of Viral Diseases, National Center for Immunization and Respiratory Diseases, USA
MMWR Recomm Rep 57:1-30; quiz CE2-4. 2008..Before administration of zoster vaccine, patients do not need to be asked about their history of varicella (chickenpox) or to have serologic testing conducted to determine varicella immunity...
Prevention of pertussis, tetanus, and diphtheria among pregnant and postpartum women and their infants recommendations of the Advisory Committee on Immunization Practices (ACIP)Trudy V Murphy
Division of Bacterial Diseases, National Center for Immunization and Respiratory Diseases, Atlanta, GA 30333, USA
MMWR Recomm Rep 57:1-51. 2008....
Where high-risk adults receive influenza vaccine during a shortageRu-Chien Chi
Arch Intern Med 167:2366-8. 2007
Influenza vaccine for childrenKathleen M Neuzil
Clin Infect Dis 38:689-91. 2004
Annual universal influenza vaccination: ready or not?Jon S Abramson
Department of Pediatrics, Wake Forest University School of Medicine, Winston Salem, NC 27157, USA
Clin Infect Dis 42:132-5. 2006..The 5-year experience of a free influenza vaccination program for everyone > or =6 months of age in the Canadian province of Ontario is reviewed...
