Research Topics
| P G NestorSummaryAffiliation: University of Massachusetts Country: USA Publications
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Detail Information
Publications
Dissociable contributions of MRI volume reductions of superior temporal and fusiform gyri to symptoms and neuropsychology in schizophreniaPaul G Nestor
Department of Psychology, University of Massachusetts, Boston, MA 02125 3393, United States
Schizophr Res 91:103-6. 2007..STG and FG volume reductions may each make distinct contributions to symptoms and cognitive deficits of schizophrenia...
Neuropsychological variability, symptoms, and brain imaging in chronic schizophreniaPaul G Nestor
Department of Psychology, University of Massachusetts, Boston, MA, 02125 3393, USA
Brain Imaging Behav 7:68-76. 2013....- Left auditory cortex gamma synchronization and auditory hallucination symptoms in schizophreniaKevin M Spencer
Research Service, Veterans Affairs Boston Healthcare System and Department of Psychiatry, Harvard Medical School, Research 151C, 150 S, Huntington Ave, Boston, MA 02130, USA
BMC Neurosci 10:85. 2009..A 5-dipole model was fit from the HC grand average ASSR, with 2 pairs of superior temporal dipoles and a deep midline dipole. Time-frequency decomposition was performed on the scalp EEG and source data... - Word priming in schizophrenia: associational and semantic influencesPaul G Nestor
Clinical Neuroscience Division, Laboratory of Neuroscience, Boston VA Health Care System Brockton Division, Department of Psychiatry, Harvard Medical School, Boston, MA, USA
Schizophr Res 82:139-42. 2006..Schizophrenic patients may show an associational bias, restricting semantic integration and contributing to their disturbed thinking... - Attentional networks and cingulum bundle in chronic schizophreniaPaul G Nestor
Department of Psychology, University of Massachusetts, Boston, MA 02125 3393, USA
Schizophr Res 90:308-15. 2007..In addition, left CB fractional anisotropy correlated significantly with orienting of attention. Smaller right CB volume also correlated with reduced alertness, but not when covarying for medication and illness duration... - Retrieval-induced forgetting in schizophreniaPaul G Nestor
Clinical Neuroscience Division, Laboratory of Neuroscience, Boston VA Health Care System Brockton Division, MA, USA
Schizophr Res 75:199-209. 2005..Results suggested faulty specificity/distinctiveness for encoding and retrieval, but not abnormal RIF in the associative memory disturbance of SZ... 
Mental disorder and violence: personality dimensions and clinical featuresPaul G Nestor
Psychiatry 116A, Brockton VAMC, 940 Belmont Street, Brockton, MA 02301, USA
Am J Psychiatry 159:1973-8. 2002..This review examines the role of personality dimensions in the greater rates of violence that have now been established to accompany certain classes of mental disorders...- Episodic memory and neuroimaging of hippocampus and fornix in chronic schizophreniaPaul G Nestor
Department of Psychology, University of Massachusetts, Boston, MA 02125 3393, USA
Psychiatry Res 155:21-8. 2007..However, increased hippocampal volume correlated, in the negative direction, with lower scores for executive functioning and IQ in the control subset. Implications of these results are discussed... - Semantic disturbance in schizophrenia and its relationship to the cognitive neuroscience of attentionP G Nestor
Department of Psychiatry, Harvard Medical School, Brockton VAMC 116A, 940 Belmont Street, Brockton, MA 02401, USA
Biol Psychol 57:23-46. 2001..We propose a similar failure of NMDA-mediated recurrent inhibition as a candidate biological substrate for attention and semantic anomalies of schizophrenia... - Neuropsychological disturbance in schizophrenia: a diffusion tensor imaging studyPaul G Nestor
Department of Psychology, University of Massachusetts, Boston, MA 02125 3393, USA
Neuropsychology 22:246-54. 2008..Reduced white matter of the CB and the UF may each make distinct contributions to neuropsychological disturbance in schizophrenia... - Neuropsychological correlates of diffusion tensor imaging in schizophreniaPaul G Nestor
Clinical Neuroscience Division, Laboratory of Neuroscience, Boston Veterans Affairs Health Care System Brockton Division, Brockton, MA 02301, USA
Neuropsychology 18:629-37. 2004..The data suggested abnormal DTI patterns linking declarative-episodic verbal memory deficits to the left UF and executive function deficits to the left CB among patients with schizophrenia... - Distinct contribution of working memory and social comprehension failures in neuropsychological impairment in schizophreniaPaul G Nestor
Department of Psychology, University of Massachusetts, Boston, MA 02125 3393, USA
J Nerv Ment Dis 198:206-12. 2010..Failures in social comprehension and executive attentional control may account for distinct sources of variance in the neuropsychological impairment of schizophrenia... - Comparing prefrontal gray and white matter contributions to intelligence and decision making in schizophrenia and healthy controlsPaul G Nestor
Department of Psychology, University of Massachusetts, Boston and Clinical Neuroscience Division, Laboratory of Neuroscience, Boston VA Healthcare System Brockton Division, Brockton, Massachusetts 02125 3393, USA
Neuropsychology 24:121-9. 2010..These results point to the potentially important role of CB white matter in the neuropsychological disturbance in schizophrenia... - Gaze cueing of attention in schizophrenia: individual differences in neuropsychological functioning and symptomsPaul G Nestor
Department of Psychology, University of Massachusetts, Boston, MA 02125 3393, USA
J Clin Exp Neuropsychol 32:281-8. 2010..Reduced inhibitory aftereffect in RT for eye-gaze cues may reflect disease-related abnormalities in social attention... - Psychosis, psychopathy, and homicide: a preliminary neuropsychological inquiryPaul G Nestor
Department of Psychology, University of Massachusetts, Boston, MA 02125 3393, USA
Am J Psychiatry 159:138-40. 2002..This study attempted to statistically distinguish subgroups of murderers with mental disorders from among 26 hospitalized men (mean age=34 years) who were committed to a maximum security forensic hospital... - Abnormal inhibitory processes in semantic networks in schizophreniaM Niznikiewicz
Boston VA Medical Center, Boston, MA, USA
Int J Psychophysiol 75:133-40. 2010..Furthermore, reduced N400 in the unrelated condition found in this study suggests that the abnormality was related to inefficient early inhibitory processes... - Diffusion tractography of the fornix in schizophreniaJ Fitzsimmons
Psychiatry Neuroimaging Laboratory, Department of Psychiatry, Brigham and Women s Hospital, Harvard Medical School, Boston, MA, USA
Schizophr Res 107:39-46. 2009..We applied these techniques to quantify fornix diffusion anisotropy in schizophrenia... - Identification of neural circuits underlying P300 abnormalities in schizophreniaB F O'Donnell
Department of Psychiatry, Harvard Medical School, Brockton, MA, USA
Psychophysiology 36:388-98. 1999.... - DTI and MTR abnormalities in schizophrenia: analysis of white matter integrityM Kubicki
Clinical Neuroscience Division, Laboratory of Neuroscience, Boston VA Healthcare System Brockton Division, Department of Psychiatry, Harvard Medical School, Brockton, MA 02301, USA
Neuroimage 26:1109-18. 2005.... - ERP assessment of visual and auditory language processing in schizophreniaM A Niznikiewicz
Department of Psychiatry, Harvard Medical School, Massachusetts, USA
J Abnorm Psychol 106:85-94. 1997..These results suggest that language abnormalities in schizophrenia are related to a dysfunction in the language system and not to a general cognitive dysfunction, and may be related to poor use of context in patients with schizophrenia... - Functional neuroimaging of word priming in males with chronic schizophreniaS Duke Han
Department of Psychology, Loyola University Chicago, Chicago, IL 60626, USA
Neuroimage 35:273-82. 2007..This may reflect a disease-related disturbance in functional connectivity of lexical activation, which in turn may be associated with clinical symptomatology... - Shape of caudate nucleus and its cognitive correlates in neuroleptic-naive schizotypal personality disorderJames J Levitt
Department of Psychiatry, Veterans Affairs Boston Healthcare System, Brockton, Massachusetts 02301, USA
Biol Psychiatry 55:177-84. 2004.... - Parametric manipulations of auditory stimuli differentially affect P3 amplitude in schizophrenics and controlsD F Salisbury
Harvard Medical School, Department of Psychiatry, Brockton Veterans Affairs Medical Center
Psychophysiology 31:29-36. 1994.... - Event-related potentials elicited during a context-free homograph task in normal versus schizophrenic subjectsD F Salisbury
Department of Psychiatry, Harvard Medical School, Boston, Massachusetts, USA
Psychophysiology 37:456-63. 2000.... - The role of retrieval inhibition in the associative memory impairment of schizophreniaChristopher G AhnAllen
Department of Psychology, University of Massachusetts Boston, 100 Morrissey Blvd, Boston, MA 02125, USA
Psychiatry Res 150:43-50. 2007..Different patterns of baseline practiced retrieval for weak associate pairs in schizophrenia may explain this finding. The results failed to support faulty RIF in the associative memory impairment of schizophrenia... - Cognitive dysfunction in schizophrenia: unifying basic research and clinical aspectsR W McCarley
Harvard Medical School, Department of Psychiatry, Brockton, MA 02401, USA
Eur Arch Psychiatry Clin Neurosci 249:69-82. 1999..g. cat-dog, a result compatible with behavioral data. Other N400 data strongly and directly suggest that schizophrenics do not efficiently utilize context... - The startle reflex in schizophrenia: habituation and personality correlatesSare J Akdag
Department of Psychology, University of Massachusetts Boston, 100 Morrissey Boulevard, Boston, MA 02125, USA
Schizophr Res 64:165-73. 2003..The relationship of these findings to cognitive disturbances in schizophrenia is considered and directions for future research are discussed... - Cingulate fasciculus integrity disruption in schizophrenia: a magnetic resonance diffusion tensor imaging studyMarek Kubicki
Clinical Neuroscience Division, Laboratory of Neuroscience, Boston VA Healthcare System-Brockton Division, and Department of Psychiatry, Harvard Medical School, Brockton, Massachusetts 02301, USA
Biol Psychiatry 54:1171-80. 2003..These data provide strong evidence for CB disruptions in schizophrenia, which may be related to disease-related attention and working memory abnormalities... - Corpus callosum abnormalities and their association with psychotic symptoms in patients with schizophreniaThomas J Whitford
Psychiatry Neuroimaging Laboratory, Department of Psychiatry, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02215, USA
Biol Psychiatry 68:70-7. 2010.... - A new statistical method for testing hypotheses of neuropsychological/MRI relationships in schizophrenia: partial least squares analysisPaul G Nestor
Harvard Medical School, Boston, MA, USA
Schizophr Res 53:57-66. 2002.... - An fMRI study of semantic processing in men with schizophreniaM Kubicki
Clinical Neuroscience Division, Laboratory of Neuroscience, Boston VA Healthcare System Brockton Division, Department of Psychiatry, Harvard Medical School, Brockton, MA 02301, USA
Neuroimage 20:1923-33. 2003.... - Association between reduced extraversion and right posterior fusiform gyrus gray matter reduction in chronic schizophreniaToshiaki Onitsuka
Department of Psychiatry, Boston VA Healthcare System-Brockton Division, Harvard Medical School, 940 Belmont St, Brockton, MA 02301, USA
Am J Psychiatry 162:599-601. 2005..CONCLUSIONS: Reduced right posterior fusiform gyrus volume may contribute to disease-related social disturbances, characterized by both low extraversion and reduced sensitivity to human faces... - Fusiform gyrus volume reduction and facial recognition in chronic schizophreniaToshiaki Onitsuka
Clinical Neuroscience Division, Laboratory of Neuroscience, Department of Psychiatry, Boston VA Healthcare System, Brockton, MA 02301, USA
Arch Gen Psychiatry 60:349-55. 2003..CONCLUSION: These results suggest that neuroanatomic FG abnormalities underlie at least some of the deficits associated with facial recognition in schizophrenia... - Uncinate fasciculus findings in schizophrenia: a magnetic resonance diffusion tensor imaging studyMarek Kubicki
Department of Psychiatry, Harvard Medical School and VA Boston Healthcare System-Brockton Division, MA 02301, USA
Am J Psychiatry 159:813-20. 2002.... - Fornix integrity and hippocampal volume in male schizophrenic patientsNoriomi Kuroki
Clinical Neuroscience Division, Laboratory of Neuroscience, Department of Psychiatry, Boston VA Healthcare System, Brockton Division, and Harvard Medical School, Brockton, Massachusetts, USA
Biol Psychiatry 60:22-31. 2006..CONCLUSIONS: These findings demonstrate a disruption in fornix integrity in patients with schizophrenia... - IQ subtypes in schizophrenia: distinct symptom and neuropsychological profilesAnya I Potter
University of Massachusetts at Boston, Boston, MA, USA
J Nerv Ment Dis 198:580-5. 2010..Cluster symptom and neuropsychological profiles may help to validate empirically-derived IQ subtypes in schizophrenia... - Associative memory in chronic schizophrenia: a computational modelS Duke Han
University of Massachusetts, Boston, MA, USA
Schizophr Res 61:255-63. 2003..These findings provide support for the use of computational models to investigate dynamics of associative word recall in patients with chronic schizophrenia... - Age-related deficits in fronto-temporal connections in schizophrenia: a diffusion tensor imaging studyGudrun Rosenberger
Psychiatry Neuroimaging Laboratory, Department of Psychiatry and Radiology, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02215, United States
Schizophr Res 102:181-8. 2008..Using diffusion tensor imaging tractography, we investigated the relationship between age and fiber integrity in patients with schizophrenia vs. healthy adults... - Color Stroop and negative priming in schizophrenia: an fMRI studyLida Ungar
Psychiatry Neuroimaging Laboratory, Department of Psychiatry, Brigham and Women s Hospital, Harvard Medical School, 1249 Boylston Street 3rd Floor, Boston, MA 02215, USA
Psychiatry Res 181:24-9. 2010..These different patterns of fMRI activation may reflect faulty interaction in schizophrenia within networks of brain regions that are vital to selective attention... - Orbitofrontal volume deficit in schizophrenia and thought disorderMotoaki Nakamura
Clinical Neuroscience Division, Laboratory of Neuroscience, Department of Psychiatry, Veterans Affairs Boston Healthcare System, Brockton Division, Brockton, MA 02301, USA
Brain 131:180-95. 2008..In HC the finding of a quantitative association between OFC volume and IGT performance constitutes, to our knowledge, the first report of this association... - Neural synchrony indexes disordered perception and cognition in schizophreniaKevin M Spencer
Department of Psychiatry, Veterans Affairs Boston Healthcare System, Harvard Medical School, Psychiatry 116A, 940 Belmont Street, Brockton, MA 02301, USA
Proc Natl Acad Sci U S A 101:17288-93. 2004..These data provide support for linking dysfunctional neural circuitry and the core symptoms of schizophrenia... - Spatial frequency discrimination in schizophreniaBRIAN F O'DONNELL
Department of Psychology, Indiana University, Bloomington 47405, USA
J Abnorm Psychol 111:620-5. 2002..These findings suggest a disturbance of right hemisphere mechanisms involved in spatial perception and attention in schizophrenia... - Altered orbitofrontal sulcogyral pattern in schizophreniaMotoaki Nakamura
Clinical Neuroscience Division, Laboratory of Neuroscience, Department of Psychiatry, Veterans Affairs Boston Healthcare System, Brockton Division, Brockton, MA, USA
Brain 130:693-707. 2007.... - fMRI of lexical-semantic priming in a chronic schizophrenia patientS Duke Han
Department of Psychiatry, University of California San Diego, San Diego, California, USA
Appl Neuropsychol 13:51-7. 2006.... - The P3 auditory event-related brain potential indexes major personality traitsR J Gurrera
Department of Psychiatry, Harvard Medical School and Brockton DVAMC, Brockton, Massachusetts 02301, USA
Biol Psychiatry 49:922-9. 2001..Our results suggest that processes indexed by auditory P3 amplitude are related to these broad personality dimensions in healthy individuals... - Semantic dysfunction in women with schizotypal personality disorderMargaret A Niznikiewicz
Department of Psychiatry, Harvard Medical School, Boston, MA, USA
Am J Psychiatry 159:1767-74. 2002..The N400 component of the EEG event-related potentials was used as a probe of semantic processes... - Auditory P3 indexes personality traits and cognitive function in healthy men and womenRonald J Gurrera
Harvard Medical School, Department of Psychiatry, Boston MA, USA
Psychiatry Res 133:215-28. 2005..The physiological significance of these relationships is not yet clear, but these results suggest that neural assemblies indexed by P3 may subserve both elemental cognition and healthy personality function... - Abnormal neural synchrony in schizophreniaKevin M Spencer
Department of Psychiatry, Harvard Medical School/Veterans Affairs Boston Healthcare System, Brockton, Massachusetts 02301, USA
J Neurosci 23:7407-11. 2003..These findings support the hypothesis that schizophrenia is associated with impaired neural circuitry demonstrated as a failure of gamma band synchronization, especially in the 40 Hz range... - Processing sentence context in women with schizotypal personality disorder: an ERP studyMargaret A Niznikiewicz
Department of Psychiatry, Harvard Medical School, Neuroscience Laboratory, Brockton West Roxbury VAMC, Brockton, Massachusetts 02301, USA
Psychophysiology 41:367-71. 2004..In SPD women, relative to their comparison group, a more negative N400 was found only to auditory congruent sentences... - Personality differences in schizophrenia are related to performance on neuropsychological tasksRonald J Gurrera
VA Boston Healthcare System, Boston and Brockton, Massachusetts 02301, USA
J Nerv Ment Dis 193:714-21. 2005..Longitudinal studies utilizing more comprehensive measures of neurocognitive performance are needed to define further the relationship between neuropsychological function and personality in schizophrenia... - Semantic bias, homograph comprehension, and event-related potentials in schizophreniaDean F Salisbury
Cognitive Neuroscience Laboratory NBG21, Harvard Medical School at McLean Hospital, 115 Mill Street, Belmont, MA 02478, USA
Clin Neurophysiol 113:383-95. 2002..Combined behavioral and event-related potential (ERP) data can indicate the nature and timing of such abnormalities... - Early nicotine withdrawal and transdermal nicotine effects on neurocognitive performance in schizophreniaChristopher G AhnAllen
Center for Alcohol and Addictions Studies, Brown University, 121 South Main St, Providence, RI, 02912, USA
Schizophr Res 100:261-9. 2008.... - Sentence completion test in combat veterans with and without PTSD: preliminary findingsMatthew O Kimble
Boston VA Healthcare Network, Behavioral Science Division, National Center for PTSD, Boston University School of Medicine, MA 02130, USA
Psychiatry Res 113:303-7. 2002..The veterans with PTSD completed sentences with significantly more trauma-relevant final words than those without PTSD. Findings are interpreted with respect to current language models and information-processing theories of PTSD...