P G Nestor

Summary

Affiliation: University of Massachusetts
Country: USA

Publications

  1. pmc Dissociable contributions of MRI volume reductions of superior temporal and fusiform gyri to symptoms and neuropsychology in schizophrenia
    Paul G Nestor
    Department of Psychology, University of Massachusetts, Boston, MA 02125 3393, United States
    Schizophr Res 91:103-6. 2007
  2. pmc In search of the functional neuroanatomy of sociality: MRI subdivisions of orbital frontal cortex and social cognition
    Paul G Nestor
    Department of Psychology, University of Massachusetts, Boston, USA
    Soc Cogn Affect Neurosci 8:460-7. 2013
  3. doi request reprint Neuropsychological variability, symptoms, and brain imaging in chronic schizophrenia
    Paul G Nestor
    Department of Psychology, University of Massachusetts, Boston, MA 02125 3393, USA
    Brain Imaging Behav 7:68-76. 2013
  4. pmc Left auditory cortex gamma synchronization and auditory hallucination symptoms in schizophrenia
    Kevin M Spencer
    Research Service, Veterans Affairs Boston Healthcare System and Department of Psychiatry, Harvard Medical School, Research 151C, 150 S, Huntington Ave, Boston, MA 02130, USA
    BMC Neurosci 10:85. 2009
  5. ncbi request reprint Episodic memory and neuroimaging of hippocampus and fornix in chronic schizophrenia
    Paul G Nestor
    Department of Psychology, University of Massachusetts, Boston, MA 02125 3393, USA
    Psychiatry Res 155:21-8. 2007
  6. ncbi request reprint Mental disorder and violence: personality dimensions and clinical features
    Paul G Nestor
    Psychiatry 116A, Brockton VAMC, 940 Belmont Street, Brockton, MA 02301, USA
    Am J Psychiatry 159:1973-8. 2002
  7. pmc Word priming in schizophrenia: associational and semantic influences
    Paul G Nestor
    Clinical Neuroscience Division, Laboratory of Neuroscience, Boston VA Health Care System Brockton Division, Department of Psychiatry, Harvard Medical School, Boston, MA, USA
    Schizophr Res 82:139-42. 2006
  8. pmc Retrieval-induced forgetting in schizophrenia
    Paul G Nestor
    Clinical Neuroscience Division, Laboratory of Neuroscience, Boston VA Health Care System Brockton Division, MA, USA
    Schizophr Res 75:199-209. 2005
  9. pmc Neuropsychological correlates of diffusion tensor imaging in schizophrenia
    Paul G Nestor
    Clinical Neuroscience Division, Laboratory of Neuroscience, Boston Veterans Affairs Health Care System Brockton Division, Brockton, MA 02301, USA
    Neuropsychology 18:629-37. 2004
  10. pmc Semantic disturbance in schizophrenia and its relationship to the cognitive neuroscience of attention
    P G Nestor
    Department of Psychiatry, Harvard Medical School, Brockton VAMC 116A, 940 Belmont Street, Brockton, MA 02401, USA
    Biol Psychol 57:23-46. 2001

Collaborators

Detail Information

Publications54

  1. pmc Dissociable contributions of MRI volume reductions of superior temporal and fusiform gyri to symptoms and neuropsychology in schizophrenia
    Paul G Nestor
    Department of Psychology, University of Massachusetts, Boston, MA 02125 3393, United States
    Schizophr Res 91:103-6. 2007
    ..STG and FG volume reductions may each make distinct contributions to symptoms and cognitive deficits of schizophrenia...
  2. pmc In search of the functional neuroanatomy of sociality: MRI subdivisions of orbital frontal cortex and social cognition
    Paul G Nestor
    Department of Psychology, University of Massachusetts, Boston, USA
    Soc Cogn Affect Neurosci 8:460-7. 2013
    ..To our knowledge, these findings are the first to show evidence linking normal variation in OFC subregions and different aspects of social cognition...
  3. doi request reprint Neuropsychological variability, symptoms, and brain imaging in chronic schizophrenia
    Paul G Nestor
    Department of Psychology, University of Massachusetts, Boston, MA 02125 3393, USA
    Brain Imaging Behav 7:68-76. 2013
    ....
  4. pmc Left auditory cortex gamma synchronization and auditory hallucination symptoms in schizophrenia
    Kevin M Spencer
    Research Service, Veterans Affairs Boston Healthcare System and Department of Psychiatry, Harvard Medical School, Research 151C, 150 S, Huntington Ave, Boston, MA 02130, USA
    BMC Neurosci 10:85. 2009
    ..A 5-dipole model was fit from the HC grand average ASSR, with 2 pairs of superior temporal dipoles and a deep midline dipole. Time-frequency decomposition was performed on the scalp EEG and source data...
  5. ncbi request reprint Episodic memory and neuroimaging of hippocampus and fornix in chronic schizophrenia
    Paul G Nestor
    Department of Psychology, University of Massachusetts, Boston, MA 02125 3393, USA
    Psychiatry Res 155:21-8. 2007
    ..However, increased hippocampal volume correlated, in the negative direction, with lower scores for executive functioning and IQ in the control subset. Implications of these results are discussed...
  6. ncbi request reprint Mental disorder and violence: personality dimensions and clinical features
    Paul G Nestor
    Psychiatry 116A, Brockton VAMC, 940 Belmont Street, Brockton, MA 02301, USA
    Am J Psychiatry 159:1973-8. 2002
    ..This review examines the role of personality dimensions in the greater rates of violence that have now been established to accompany certain classes of mental disorders...
  7. pmc Word priming in schizophrenia: associational and semantic influences
    Paul G Nestor
    Clinical Neuroscience Division, Laboratory of Neuroscience, Boston VA Health Care System Brockton Division, Department of Psychiatry, Harvard Medical School, Boston, MA, USA
    Schizophr Res 82:139-42. 2006
    ..Schizophrenic patients may show an associational bias, restricting semantic integration and contributing to their disturbed thinking...
  8. pmc Retrieval-induced forgetting in schizophrenia
    Paul G Nestor
    Clinical Neuroscience Division, Laboratory of Neuroscience, Boston VA Health Care System Brockton Division, MA, USA
    Schizophr Res 75:199-209. 2005
    ..Results suggested faulty specificity/distinctiveness for encoding and retrieval, but not abnormal RIF in the associative memory disturbance of SZ...
  9. pmc Neuropsychological correlates of diffusion tensor imaging in schizophrenia
    Paul G Nestor
    Clinical Neuroscience Division, Laboratory of Neuroscience, Boston Veterans Affairs Health Care System Brockton Division, Brockton, MA 02301, USA
    Neuropsychology 18:629-37. 2004
    ..The data suggested abnormal DTI patterns linking declarative-episodic verbal memory deficits to the left UF and executive function deficits to the left CB among patients with schizophrenia...
  10. pmc Semantic disturbance in schizophrenia and its relationship to the cognitive neuroscience of attention
    P G Nestor
    Department of Psychiatry, Harvard Medical School, Brockton VAMC 116A, 940 Belmont Street, Brockton, MA 02401, USA
    Biol Psychol 57:23-46. 2001
    ..We propose a similar failure of NMDA-mediated recurrent inhibition as a candidate biological substrate for attention and semantic anomalies of schizophrenia...
  11. pmc Attentional networks and cingulum bundle in chronic schizophrenia
    Paul G Nestor
    Department of Psychology, University of Massachusetts, Boston, MA 02125 3393, USA
    Schizophr Res 90:308-15. 2007
    ..In addition, left CB fractional anisotropy correlated significantly with orienting of attention. Smaller right CB volume also correlated with reduced alertness, but not when covarying for medication and illness duration...
  12. pmc Gaze cueing of attention in schizophrenia: individual differences in neuropsychological functioning and symptoms
    Paul G Nestor
    Department of Psychology, University of Massachusetts, Boston, MA 02125 3393, USA
    J Clin Exp Neuropsychol 32:281-8. 2010
    ..Reduced inhibitory aftereffect in RT for eye-gaze cues may reflect disease-related abnormalities in social attention...
  13. ncbi request reprint Psychosis, psychopathy, and homicide: a preliminary neuropsychological inquiry
    Paul G Nestor
    Department of Psychology, University of Massachusetts, Boston, MA 02125 3393, USA
    Am J Psychiatry 159:138-40. 2002
    ..This study attempted to statistically distinguish subgroups of murderers with mental disorders from among 26 hospitalized men (mean age=34 years) who were committed to a maximum security forensic hospital...
  14. pmc Neuropsychological disturbance in schizophrenia: a diffusion tensor imaging study
    Paul G Nestor
    Department of Psychology, University of Massachusetts, Boston, MA 02125 3393, USA
    Neuropsychology 22:246-54. 2008
    ..Reduced white matter of the CB and the UF may each make distinct contributions to neuropsychological disturbance in schizophrenia...
  15. pmc Comparing prefrontal gray and white matter contributions to intelligence and decision making in schizophrenia and healthy controls
    Paul G Nestor
    Department of Psychology, University of Massachusetts, Boston and Clinical Neuroscience Division, Laboratory of Neuroscience, Boston VA Healthcare System Brockton Division, Brockton, Massachusetts 02125 3393, USA
    Neuropsychology 24:121-9. 2010
    ..These results point to the potentially important role of CB white matter in the neuropsychological disturbance in schizophrenia...
  16. doi request reprint Distinct contribution of working memory and social comprehension failures in neuropsychological impairment in schizophrenia
    Paul G Nestor
    Department of Psychology, University of Massachusetts, Boston, MA 02125 3393, USA
    J Nerv Ment Dis 198:206-12. 2010
    ..Failures in social comprehension and executive attentional control may account for distinct sources of variance in the neuropsychological impairment of schizophrenia...
  17. doi request reprint Abnormal inhibitory processes in semantic networks in schizophrenia
    M Niznikiewicz
    Boston VA Medical Center, Boston, MA, USA
    Int J Psychophysiol 75:133-40. 2010
    ..Furthermore, reduced N400 in the unrelated condition found in this study suggests that the abnormality was related to inefficient early inhibitory processes...
  18. pmc Diffusion tractography of the fornix in schizophrenia
    J Fitzsimmons
    Psychiatry Neuroimaging Laboratory, Department of Psychiatry, Brigham and Women s Hospital, Harvard Medical School, Boston, MA, USA
    Schizophr Res 107:39-46. 2009
    ..We applied these techniques to quantify fornix diffusion anisotropy in schizophrenia...
  19. pmc Identification of neural circuits underlying P300 abnormalities in schizophrenia
    B F O'Donnell
    Department of Psychiatry, Harvard Medical School, Brockton, MA, USA
    Psychophysiology 36:388-98. 1999
    ....
  20. pmc DTI and MTR abnormalities in schizophrenia: analysis of white matter integrity
    M Kubicki
    Clinical Neuroscience Division, Laboratory of Neuroscience, Boston VA Healthcare System Brockton Division, Department of Psychiatry, Harvard Medical School, Brockton, MA 02301, USA
    Neuroimage 26:1109-18. 2005
    ....
  21. ncbi request reprint ERP assessment of visual and auditory language processing in schizophrenia
    M A Niznikiewicz
    Department of Psychiatry, Harvard Medical School, Massachusetts, USA
    J Abnorm Psychol 106:85-94. 1997
    ..These results suggest that language abnormalities in schizophrenia are related to a dysfunction in the language system and not to a general cognitive dysfunction, and may be related to poor use of context in patients with schizophrenia...
  22. pmc Shape of caudate nucleus and its cognitive correlates in neuroleptic-naive schizotypal personality disorder
    James J Levitt
    Department of Psychiatry, Veterans Affairs Boston Healthcare System, Brockton, Massachusetts 02301, USA
    Biol Psychiatry 55:177-84. 2004
    ..We believe MRI shape analysis complements traditional MRI volume measurements...
  23. pmc Functional neuroimaging of word priming in males with chronic schizophrenia
    S Duke Han
    Department of Psychology, Loyola University Chicago, Chicago, IL 60626, USA
    Neuroimage 35:273-82. 2007
    ..This may reflect a disease-related disturbance in functional connectivity of lexical activation, which in turn may be associated with clinical symptomatology...
  24. pmc Parametric manipulations of auditory stimuli differentially affect P3 amplitude in schizophrenics and controls
    D F Salisbury
    Harvard Medical School, Department of Psychiatry, Brockton Veterans Affairs Medical Center
    Psychophysiology 31:29-36. 1994
    ....
  25. pmc Event-related potentials elicited during a context-free homograph task in normal versus schizophrenic subjects
    D F Salisbury
    Department of Psychiatry, Harvard Medical School, Boston, Massachusetts, USA
    Psychophysiology 37:456-63. 2000
    ....
  26. pmc The role of retrieval inhibition in the associative memory impairment of schizophrenia
    Christopher G AhnAllen
    Department of Psychology, University of Massachusetts Boston, 100 Morrissey Blvd, Boston, MA 02125, USA
    Psychiatry Res 150:43-50. 2007
    ..Different patterns of baseline practiced retrieval for weak associate pairs in schizophrenia may explain this finding. The results failed to support faulty RIF in the associative memory impairment of schizophrenia...
  27. pmc An fMRI study of semantic processing in men with schizophrenia
    M Kubicki
    Clinical Neuroscience Division, Laboratory of Neuroscience, Boston VA Healthcare System Brockton Division, Department of Psychiatry, Harvard Medical School, Brockton, MA 02301, USA
    Neuroimage 20:1923-33. 2003
    ....
  28. pmc Cognitive dysfunction in schizophrenia: unifying basic research and clinical aspects
    R W McCarley
    Harvard Medical School, Department of Psychiatry, Brockton, MA 02401, USA
    Eur Arch Psychiatry Clin Neurosci 249:69-82. 1999
    ..g. cat-dog, a result compatible with behavioral data. Other N400 data strongly and directly suggest that schizophrenics do not efficiently utilize context...
  29. pmc Corpus callosum abnormalities and their association with psychotic symptoms in patients with schizophrenia
    Thomas J Whitford
    Psychiatry Neuroimaging Laboratory, Department of Psychiatry, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02215, USA
    Biol Psychiatry 68:70-7. 2010
    ....
  30. pmc The startle reflex in schizophrenia: habituation and personality correlates
    Sare J Akdag
    Department of Psychology, University of Massachusetts Boston, 100 Morrissey Boulevard, Boston, MA 02125, USA
    Schizophr Res 64:165-73. 2003
    ..The relationship of these findings to cognitive disturbances in schizophrenia is considered and directions for future research are discussed...
  31. pmc Cingulate fasciculus integrity disruption in schizophrenia: a magnetic resonance diffusion tensor imaging study
    Marek Kubicki
    Clinical Neuroscience Division, Laboratory of Neuroscience, Boston VA Healthcare System Brockton Division, and Department of Psychiatry, Harvard Medical School, Brockton, Massachusetts 02301, USA
    Biol Psychiatry 54:1171-80. 2003
    ..These data provide strong evidence for CB disruptions in schizophrenia, which may be related to disease-related attention and working memory abnormalities...
  32. pmc A new statistical method for testing hypotheses of neuropsychological/MRI relationships in schizophrenia: partial least squares analysis
    Paul G Nestor
    Harvard Medical School, Boston, MA, USA
    Schizophr Res 53:57-66. 2002
    ....
  33. pmc Uncinate fasciculus findings in schizophrenia: a magnetic resonance diffusion tensor imaging study
    Marek Kubicki
    Department of Psychiatry, Harvard Medical School and VA Boston Healthcare System Brockton Division, MA 02301, USA
    Am J Psychiatry 159:813-20. 2002
    ..Here the authors focus on fiber tracts forming temporal-frontal connections...
  34. pmc Fornix integrity and hippocampal volume in male schizophrenic patients
    Noriomi Kuroki
    Clinical Neuroscience Division, Laboratory of Neuroscience, Department of Psychiatry, Boston VA Healthcare System, Brockton Division, and Harvard Medical School, Brockton, Massachusetts, USA
    Biol Psychiatry 60:22-31. 2006
    ..Few studies have evaluated the fornix in schizophrenia, however. A focus on fornix abnormalities and their association with hippocampal abnormalities might figure importantly in our understanding of the pathophysiology of schizophrenia...
  35. ncbi request reprint Fusiform gyrus volume reduction and facial recognition in chronic schizophrenia
    Toshiaki Onitsuka
    Clinical Neuroscience Division, Laboratory of Neuroscience, Department of Psychiatry, Boston VA Healthcare System, Brockton, MA 02301, USA
    Arch Gen Psychiatry 60:349-55. 2003
    ....
  36. pmc Association between reduced extraversion and right posterior fusiform gyrus gray matter reduction in chronic schizophrenia
    Toshiaki Onitsuka
    Department of Psychiatry, Boston VA Healthcare System Brockton Division, Harvard Medical School, 940 Belmont St, Brockton, MA 02301, USA
    Am J Psychiatry 162:599-601. 2005
    ..The authors examined the association between volume of the fusiform gyrus, a region involved in face processing, and the personality trait of extraversion in patients with schizophrenia...
  37. doi request reprint IQ subtypes in schizophrenia: distinct symptom and neuropsychological profiles
    Anya I Potter
    University of Massachusetts at Boston, Boston, MA, USA
    J Nerv Ment Dis 198:580-5. 2010
    ..Cluster symptom and neuropsychological profiles may help to validate empirically-derived IQ subtypes in schizophrenia...
  38. pmc Associative memory in chronic schizophrenia: a computational model
    S Duke Han
    University of Massachusetts, Boston, MA, USA
    Schizophr Res 61:255-63. 2003
    ..These findings provide support for the use of computational models to investigate dynamics of associative word recall in patients with chronic schizophrenia...
  39. pmc Age-related deficits in fronto-temporal connections in schizophrenia: a diffusion tensor imaging study
    Gudrun Rosenberger
    Psychiatry Neuroimaging Laboratory, Department of Psychiatry and Radiology, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02215, United States
    Schizophr Res 102:181-8. 2008
    ..Using diffusion tensor imaging tractography, we investigated the relationship between age and fiber integrity in patients with schizophrenia vs. healthy adults...
  40. pmc Orbitofrontal volume deficit in schizophrenia and thought disorder
    Motoaki Nakamura
    Clinical Neuroscience Division, Laboratory of Neuroscience, Department of Psychiatry, Veterans Affairs Boston Healthcare System, Brockton Division, Brockton, MA 02301, USA
    Brain 131:180-95. 2008
    ..In HC the finding of a quantitative association between OFC volume and IGT performance constitutes, to our knowledge, the first report of this association...
  41. pmc Color Stroop and negative priming in schizophrenia: an fMRI study
    Lida Ungar
    Psychiatry Neuroimaging Laboratory, Department of Psychiatry, Brigham and Women s Hospital, Harvard Medical School, 1249 Boylston Street 3rd Floor, Boston, MA 02215, USA
    Psychiatry Res 181:24-9. 2010
    ..These different patterns of fMRI activation may reflect faulty interaction in schizophrenia within networks of brain regions that are vital to selective attention...
  42. pmc Neural synchrony indexes disordered perception and cognition in schizophrenia
    Kevin M Spencer
    Department of Psychiatry, Veterans Affairs Boston Healthcare System, Harvard Medical School, Psychiatry 116A, 940 Belmont Street, Brockton, MA 02301, USA
    Proc Natl Acad Sci U S A 101:17288-93. 2004
    ..These data provide support for linking dysfunctional neural circuitry and the core symptoms of schizophrenia...
  43. ncbi request reprint fMRI of lexical-semantic priming in a chronic schizophrenia patient
    S Duke Han
    Department of Psychiatry, University of California San Diego, San Diego, California, USA
    Appl Neuropsychol 13:51-7. 2006
    ....
  44. pmc Altered orbitofrontal sulcogyral pattern in schizophrenia
    Motoaki Nakamura
    Clinical Neuroscience Division, Laboratory of Neuroscience, Department of Psychiatry, Veterans Affairs Boston Healthcare System, Brockton Division, Brockton, MA, USA
    Brain 130:693-707. 2007
    ....
  45. pmc Spatial frequency discrimination in schizophrenia
    BRIAN F O'DONNELL
    Department of Psychology, Indiana University, Bloomington 47405, USA
    J Abnorm Psychol 111:620-5. 2002
    ..These findings suggest a disturbance of right hemisphere mechanisms involved in spatial perception and attention in schizophrenia...
  46. ncbi request reprint The P3 auditory event-related brain potential indexes major personality traits
    R J Gurrera
    Department of Psychiatry, Harvard Medical School and Brockton DVAMC, Brockton, Massachusetts 02301, USA
    Biol Psychiatry 49:922-9. 2001
    ..Our results suggest that processes indexed by auditory P3 amplitude are related to these broad personality dimensions in healthy individuals...
  47. pmc Semantic dysfunction in women with schizotypal personality disorder
    Margaret A Niznikiewicz
    Department of Psychiatry, Harvard Medical School, Boston, MA, USA
    Am J Psychiatry 159:1767-74. 2002
    ..The N400 component of the EEG event-related potentials was used as a probe of semantic processes...
  48. ncbi request reprint Auditory P3 indexes personality traits and cognitive function in healthy men and women
    Ronald J Gurrera
    Harvard Medical School, Department of Psychiatry, Boston MA, USA
    Psychiatry Res 133:215-28. 2005
    ..The physiological significance of these relationships is not yet clear, but these results suggest that neural assemblies indexed by P3 may subserve both elemental cognition and healthy personality function...
  49. pmc Abnormal neural synchrony in schizophrenia
    Kevin M Spencer
    Department of Psychiatry, Harvard Medical School Veterans Affairs Boston Healthcare System, Brockton, Massachusetts 02301, USA
    J Neurosci 23:7407-11. 2003
    ..These findings support the hypothesis that schizophrenia is associated with impaired neural circuitry demonstrated as a failure of gamma band synchronization, especially in the 40 Hz range...
  50. pmc Processing sentence context in women with schizotypal personality disorder: an ERP study
    Margaret A Niznikiewicz
    Department of Psychiatry, Harvard Medical School, Neuroscience Laboratory, Brockton West Roxbury VAMC, Brockton, Massachusetts 02301, USA
    Psychophysiology 41:367-71. 2004
    ..In SPD women, relative to their comparison group, a more negative N400 was found only to auditory congruent sentences...
  51. pmc Semantic bias, homograph comprehension, and event-related potentials in schizophrenia
    Dean F Salisbury
    Cognitive Neuroscience Laboratory NBG21, Harvard Medical School at McLean Hospital, 115 Mill Street, Belmont, MA 02478, USA
    Clin Neurophysiol 113:383-95. 2002
    ..Combined behavioral and event-related potential (ERP) data can indicate the nature and timing of such abnormalities...
  52. ncbi request reprint Personality differences in schizophrenia are related to performance on neuropsychological tasks
    Ronald J Gurrera
    VA Boston Healthcare System, Boston and Brockton, Massachusetts 02301, USA
    J Nerv Ment Dis 193:714-21. 2005
    ..Longitudinal studies utilizing more comprehensive measures of neurocognitive performance are needed to define further the relationship between neuropsychological function and personality in schizophrenia...
  53. ncbi request reprint Sentence completion test in combat veterans with and without PTSD: preliminary findings
    Matthew O Kimble
    Boston VA Healthcare Network, Behavioral Science Division, National Center for PTSD, Boston University School of Medicine, MA 02130, USA
    Psychiatry Res 113:303-7. 2002
    ..The veterans with PTSD completed sentences with significantly more trauma-relevant final words than those without PTSD. Findings are interpreted with respect to current language models and information-processing theories of PTSD...
  54. pmc Early nicotine withdrawal and transdermal nicotine effects on neurocognitive performance in schizophrenia
    Christopher G AhnAllen
    Center for Alcohol and Addictions Studies, Brown University, 121 South Main St, Providence, RI, 02912, USA
    Schizophr Res 100:261-9. 2008
    ....